bms bio molecular systems Mic qpcr Ultimate Performance for Real-Time PCR Fast. Accurate. Compact. Speed Accuracy Size Connectivity

Transcription

1 bms bi mlecular systems Mic qpcr Ultimate Perfrmance fr Real-Time PCR Fast. Accurate. Cmpact. Speed Accuracy Size Cnnectivity

2 Hardware Style meets substance - ultimate perfrmance, beautiful design. Fast results withut cmprmise Speed Mic uses a patented magnetic inductin technlgy t heat samples and fan frced air fr cling. This means fast qpcr results in less than 25 min fr 35 cycles*. Back that up with a rbust ptical system that reads all channels simultaneusly and running multichannel assays has never been quicker. The Mic qpcr cycler is available in either 2 r 4 channel mdels. Each channel uses an independent high intensity LED, phtdetectr and filter set cmbining tgether t give unparalleled detectin perfrmance. Mic Vendr A Vendr B Vendr Q Run Time With a fixed ptical path and n mving parts there is never any ptical alignment r calibratin required. Even better is that n reference dyes r crsstalk cmpensatin is required. *Assays designed tward cdna targets with shrt amplicn sizes and using fast cycling cmpatible Taq plymerases Multi-run, multi-instrument, anytime Accuracy Why wait t run 384 samples? Get yur results nw and have the cnfidence yur datasets can be seamlessly cmbined using ur Prject analysis sftware at anytime. Cmparing samples between multiple runs r even multiple instruments is nw effrtless. Reprducibility acrss multiple runs n Mic is better than within a single 96 r 384 well run n many cyclers T achieve this level f precisin, the Mic real-time cycler incrprates a unique spinning aluminium rtr which has unsurpassed temperature unifrmity during bth dynamic and static peratins. All ther blck-based real-time cyclers nly prmise static unifrmity, which culd lead t variability as samples aren t heated and cled at the same rate. Yu might think this level f accuracy requires cnstant calibratin, but Mic's gd t g right ut f the bx. Yu dn't need t calibrate ever.

3 Mdern persnal design Size Mic takes up less space n the bench than yur lab bk. And weighing in at just 2 kg, this is the mst prtable, cmpact, qpcr cycler n the market. Even fur Mic's stacked tgether take up less bench space than yur current cycler. Only magnetic inductin technlgy by way f its elegant simplicity makes it pssible t achieve such a small ftprint. The custm tube frmat uses 0.1 ml strips f fur tubes and matching caps, supprting vlumes frm 5µL t 30µL. Ultra thin walls designed fr fast cycling times, pre-laded with an il verlay and in huse manufacturing guarantees the maximum pssible perfrmance fr yur applicatin. All tubes cme pre-racked fr easy lading and crrect rientatin is ensured with a tab n the first tube. Wireless rbust cmmunicatins Cnnectivity Multiple Mic s can be perated frm ne wrkstatin s 48 becmes 96, and 96 becmes 192. Bluetth technlgy means fewer cables t. Instruments can cmmunicate via Bluetth r USB cable and yu can cnnect as many as ten instruments t ne PC. This means up t 480 samples can be analysed simultaneusly. Never lse data thrugh discnnectins again. Every Mic has built in data strage t keep yur data safe even if the PC is discnnected. Recvery is autmatic as sn as the cnnectin is restred. Naturally yu want t be up and running as quickly as pssible s installatin has been made plug-and-play. It's as simple as installing the sftware and starting yur first run.

4 Sftware Simplicity with pwer - cmplex algrithms applied at the tuch f a buttn. Prj Prjects Prject based analysis lets yu cmbine multiple runs int ne analysis. With Mic s unrivalled reprducibility yu n lnger need t wrry abut batching yur experiments int ne large 96 r 384 well run. Simply cmbine yur runs int ne analysis fr any type f applicatin. By autmating the analysis prcess we eliminate the need t exprt data t third party sftware. All f the statistics are included ready fr publicatin. RQ Relative Quantificatin Mic's RQ sftware uses up-t-date mathematical mdels and well-funded statistical analysis, allwing yu t cmpare gene expressin levels fr different targets acrss multiple grups. All the necessary calculatins and statistics are carried ut within the sftware. Data is reprted bth numerically and graphically. With Mic's superir temperature unifrmity yu can easily detect differences between samples as little as 0.2 fld. AQ Abslute Quantificatin Using a standard curve, AQ allws yu t determine the abslute amunt f a genetic target. This five pint, tw fld dilutin series prduced an efficiency f 98%. The percentage variatin between the given and calculated cncentratin was n greater than 5% allwing fr accurate quantificatin f the unknwn sample.

5 Gen Melt / Allelic Discriminatin Use differentiated melt curves frm varius types f chemistries, including quenched FRET dual hybridizatin prbes, beacn prbes r Plexr t characterize a sample's gentype. Melt peaks can be inverted t accmmdate the different chemistry types. Alternatively, use hybridisatin prbes t determine gentypes thrugh Allelic Discriminatin. HRM High Reslutin Melting Mic's ptinal HRM sftware characterises DNA samples accrding t their melt behaviur s yu can identify mutatins, including difficult Class IV SNPs. HRM is the perfect tl fr applicatins including determining allele prevalence, screening fr lss f heterzygsity, DNA fingerprinting, DNA methylatin, species identificatin and calculating the rati f smatic acquired mutatins.

6 Speci catins 130 mm (265 mm lid pen) 150 mm 150 mm Electrical AC Input VAC, 50/60 Hz Thermal Perfrmance Temperature Accuracy Temperature Unifrmity Ramp Rates ± 0.25 C ± 0.05 C Heating: 4 C/s (sample) Cling: 3 C/s (sample) Optical Detectrs Excitatin Surces Channels Acquisitin Time Phtdide per channel High energy LED per channel Green: Ex. 465 nm; Em. 510 nm Yellw: Ex. 540 nm; Em. 570 nm Orange: Ex. 585 nm; Em. 618 nm Red: Ex. 635 nm; Em. 675 nm 1 s Reactin Vessels Samples per Instrument 48 Reactin Vlume Range 5-30 ml Operating Envirnment Temperature Relative Humidity C 20-80% Designed and manufactured in Australia by bms bi mlecular systems sales@bimlecularsystems.cm Head Office Unit 5/3 Nrthward St. Upper Cmera QLD 4209 AUSTRALIA T. +61 (07) Sales & Supprt Suite 504, Springfield Ave. Ptts Pint NSW 2011 AUSTRALIA T. +61 (02)