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1 ()*+ 387! "#! ".,, / ( ")*+, (-. / "# "$% $& 2! :" 23"4 3 2 ;3< 2 2 ;3< (-8 " 7J!M 67. K!6 B A!? !?79 < 4M 6 :9-! :, _. O9 7J " (K ^L A B8M N!M. K7 HI! ;6 [\# 74 ]7? A4 479 (S4c A 6 A7 49 G. K ab# 97 S.` G4 6)! 97B 93 e9m A 46M < SP7 < O9 )# *+# S.` W4 S.` G4 :& 5 O W4 2 ;7 9!9M A78 f 79 T f (<7.2 _8 3< O"479 < 23 Sb? 7U 79 T %77/5 7* 39 Sb? 79 T %22/5 7* 9 S.` G4 :! $. A * 9 7R 6. 7* 5.9 ( C i h 7* 29 +g h O"479 7* 298 +g h 7U 7* 3 27< * 9.. G " 4 Sb? A f %43 7* %3/8 7* 5 A 6 * 9 2< 6 %4/5 7* 8 (Intrauterine Device) IUD 6 %5/8 7* 63. (Oral Contraceptive Pill) OCP 6 %32/9 +g h 7U O"479.9 (C i h A 6 A7 A f 6 * 9 G A<!6M.27<.2! A 3S ab# (p = / ) (p = / 8) e#7 (@ 479 G B. h fh S4c) 3S ab# +g h 7U O"479.9 (Ci h A 6 A7 A f 6 * 9 G :% ;$.(p = / ) (p = / 8) P A A 6 479!?79 79 T :-&! (< 86/6/27 : E7! 79 T A7.7U.[] O9 Q4 N< %45 %99 6!?79 479!?79 OS 67 < 6 79 W4 87 < 23 " A7Q <!?79 G G473.[2] # 47M!46!6 Z.< (ACS) 47M 7R 6 < 6 # 79 T C9 N46M 7< G " SQ "3P 86/3/9 :3.,-7,!6 B A!? !?79 E C9 479!?79 2) (C4. HI!.[] 2!6 H4!?79 7J (K L A B8M N!M. K7 A7 I!?79 G4 OBP G.[2] O9 A 7 SQ A7P. Q78 7R American Cancer Society

2 387! "# 79 T v 6 3"K 47 S.` e#7# < 23 Sb?7U 79 T 7* 665 7* 425 +g h 7U O"479 7* 5 A6i 7* 72 +g h O" * 9 l 7R 6. 7* 8 A6i A7 9 %39/2 A 6 A7 T.L,IUD,OCP l e#7# L 23 2 IUD 6 * 9 G G3s DMPA 2< P A 3S 479 (S4c 2< * 9!6 2+ A < P 7 S.`.O IU t 97 R3 IUD 6 233<.[8] 2478 f8 O*!6 G4 %/5 2 vc G47# H4 S.`.[9] O9 (%38) O* A47h 6 2S IUD 3 W4 N 7< 7Q "47< S.` G!6 342 A ( ) A A6i IUD 6 * 9.O2 P A 3S ab# 79 T A ab# IUD yc ` < * B3# G3s 4! G..[] < O 479 A6i! * 2. OCP 233< ]7g!6 G4 7* < G4 L 2< 6 * 9 7* 4 IUD 6 * 9.[] 27< A7 Sb? vl47?!6 A7 v9 G47# H4 q O* S.` S.`.[2] %85 O9 (LD) r7i A 6 A f 6 * 9 <! 47 7"< " i N< p A 6 A7 233< 29 < 7< 479!?79? A 6 A7 m \ A 479 4z C9 e#7 5! { S.` G3s.[3] 278 7I A7 A f G < 2 lc G4 P ab# 79 T Sb? 7U Z4 5!?79 A7.7U A 7 A7P 23k 7.O9 A li!. O9 Q7 G 479 K7 A G4 O9 Q4 N< PB# 7 G4 < A? [\# A7#6.[] O9 2 A7 B AL 73 O.h K!78 (S4c 67 < C K < 2! (S.`.23 " l3 2 l 67 A 6 A7 m \ A f 479 B. h fh h2 (S4c A (2 C? ]7g 4`.23 " < A7Q "4L ( ) n97 3< ^i 7`h K 2 7 ]7g n9 7 3< Z4.[] 2 479!?79 2 9! W4 o9# A 479!?79 6 A7 A f G Q4 ]2 A 6 A7 A f <! 2 (S4c i W"4 N4Q p IUD.[2] 479!?79 O4B 479!6!3S 63 K!78 h fh (S4c. 2 Q78 7I Gq 479!?79 (LL)#.[43] O9 2 24# 87 BM G ab# 7`h N4Q IUD 6 * 9 O9! 7h 7 9 ih rg\ G. B. A O* 2 C? (2 78 O9 6 * 9 G3s.[5] < 4BM rg\ A78P A7 233< 29 A f 4 ORQ) l 7 6?\ <.2 479!?79 7`h 23 " t7s G Q78 7I N< O C K <.[] O9 *!s##?q o9# < A S.` 2S#!M 6 7 < 9 9 u6 G9 G 2 3S 479 (S4c 4 6 N A!46.[6]O9 P A 3 Christopher Cram 4 Wallin 5 Mark Mike 2 Intrauterine Device

3 5! K 8 7 <... l G ab# GS# u6 G9 < (*# G O9 2 Qc 397 G4 (C9 e9m A 46M!7 R3 G4 Z4 S.` SP7 7B 93 7Q bkg 233< SP7!6 79 T A. 2 7< # 397 6M G 7 B v"4l A7 AM 479 (S4c A 6 A7 A f h!6m 6 * LQ# 2P Q 7 o9# AM )# 4#.OQ78 7I SPSS AM! $.!6 6 %45/4 7* 8 <! N Z4 7~< u6 G9 23 7I ) %75/4 7* 28!8233< SP7 7* 322!6 O47~<!46 2S#..9-9 A7 f %3/8 7* 5.!46-3 %82/8 A7 f %96/2 7* A 6.2 A 6 < 27< * 9 r7i 6 %32/9 7* 3 r7i 6 2S.O 7Q G47 LD l * 9 (DMPA) nm 2< IUD e#7#.( 2P) OQ78 7I B 5 ()$ "@ ". ". A. =-> (-::& >, C 2+ 2S# A7 f l /8 3 HD 3/8 /3 5/8 4/5 43 3/ LD W4 6Q A7# 7 IUD 2< nm ( <6 # Sb? ) 7U A 6 A7 f 6 * 9 2 HP 6 79 T 97 HI 24 O"4z.# H` N46M 7Q A 6 A7 f.[4] 2 7R 479!?79 AC M P# A f!?79 G4. K v` BP HP S.` W4 6 A 6 A78P l A 6 A7 49 ab# 479 (h 2 h fh)(s4c R3 < A7Q A7 # P 79 T 234 SP7 OBP 49 G4 6 * Q 4 t 6C (i? 8M ` f G47# e93 # 4 A7. 78 \ 7Q o9# 6 * 9 l 97 ]2 }Q N GS# G3s!6 A 6 A7 49 (S4c A 6 A7 v9 l G ab#! GS# 79 T T 479 (S4c l.o9 2 & 5 < O9 )# *+# S.` W4 S.` G4 46M 233< SP7!6!M AM SP 9 6 7B 93 e9m A # 79 T v G Q78 R M 7* 4 <_ AM SP 6 2 l 6!9M A78 f 6 * 9 N K b. 22 \ ; A 97 < 2478 GS# 7* 382 p+ /5.OQ78 7* * 9 bkg f 6 (i? AM HP A AM HP ih 2. O * 9 bkg A3!3 (6 2 B# 397 d7? G4 397 T v36 f6m! O2B

4 387! "# 79 T IUD 6 * 9 %9/2 7* 5 ]7g.K O ASCUS (S4c 2 24 ASCUS (S4c % 6/5 7* 5 2<.O9 G 2478 [\ h!6m 6 * 9.9 (Ci h A 6 A7 f 6 * 9 P A 3S AM ab#.(3 2P) (p=/8) B LB) B ",B$ "E MN$D ". A.3 =-> HP S4c!2 ASCUS ASCUS OCP 2< 4 IUD 7U HP OP G47 7cK S.` 2M O92 Z4 b? 78 A7.7U OBP 233< SP7!6 7Q G9 G O9 9 (26-35) 39 ibi < ` O9 2 P #C.9 479!?79 o9 G9 2 *8 W4 ) (< ) bimodal 39 H46# O9 6 _. ( I W I A7.7U AC < 2+ < 6 %25 2 A G4 A O E7 AL!?79 G4 li N< A7 OBP G AC G39 24 A7.7U SQ A 7 7 B!6 ep 6 bl 9 N< # 7cK S.` 79 T 6 7#C G39!6 G4 Q< (i? G 2 BP#. 6!M! A7 I!?79 G4 G9 S.` G T A7.7U 47? 7Q G Ä2) u6 OB!s## S.` v G4 < O.[5] 52 fh S4c G47 < 2! Q4 OCP (+g h 7U O"479) G B. h %4/5 7* 3 2< G47 < %42 7* 25 7* 59 IUD 6 * 9 S4c G4 O G " 4 Sb? f 6 * 9 (+ %2.O %33/5 7* G 2478 [\ A<!6M 6 * 9 fh (S4c A 6 A7 f 6 * 9 ab# (+g h 7U O"479) G B. h.(2)2p (p =/) P A 3S AM "B$E FBD 5BD "@ ". ". A.2 =-> L) ("I+$D J 3@ ),G, G B. 9 l A7 A /5 33/ OCP IUD 2< 7U HP 39 2 Q S.` G4. S4c! S4c S4c!2 A7 f!2 5 v).(2 7U O"479) G B. S4c * S4c 29 -( +g h.9 (Ci h 5 (+g h O"479) g h 7U O" ! G4 (Ci h -+g h O"479) 74 (S4c 7 O" O9 (.9.9 (Ci h 7 +g h.23 S4c 9 7 7* 4.O9 G47 < 23! Q4.O9 %39/7 7* 3 OCP ]7g ASCUS Atypical Squamuse Cell of Undetermined Signification

5 53! K 8 7 <... l G ab# GS# nm 6 * 9 Ob"!6 ep 6 bl 9 6 o47 4!M b2 82I i h. 2#.2 4# A7 rh l! 97 7cK S.` ]2 6 4 G4 79 T 479 (S4c 7U O"479) G B. h fh S4c S.` (S.` < O9 l G47 (+g h h fh S4c. OB 3"K!s## W4 K O)# 4 K O"479) 7 * G (+g h O"479-rh "87!s## (S.` Z4 < O9 H4 S4c Ob" (S4c G4!. OB 3"K A7#C l <_ S.` (S4c l S.` G4.9 (Ci h.o9 "4L. bi S4c Ob" A7# G4 24 < O9 A7#C l <_ S.` G4 9-9 u6 G9 AC l..2 S.` 6 A7 A f G 7cK S.` A 3S ab#.9 (Ci h A (Ci h 2S# G47 7cK S.` P.O9 OCP ]7g `.9! S4c G47!LL) S.`!78.9 (Ci h OCP 233< ]7g G47# H4 G. S.` G3s.O9 K!4i b 2 ]7g A 6 A7 9 2 * 9 9 G47 < 479 A6i 7cK S.` Z4 < O9 2<. OB B. h fh S4c G 7cK S.` (+g h 7U O"479-G O"479) G A 3S ab# A 6 A7 A f T 2 24 S4c G47 4`. P O" S OCP 233< ]7g 7Q 79 < O9.9 (Ci h +g h 7U 49 6 * 9 l 7cK S.` ]2 6 4 S.` G4 b? < O9 A 6 A e#7# l <6 4 # 4 Sb? A f 6 * 9- (%43) (% 32/9) OCP -2 (% 5/8) IUD -3 (% 4/5) 2< -4 (% ) nm -5 7 h R3# A 7 O2B (6 7R 4` O9 B 3 r7i ]7g 4 7 %6r7I 6 A o47 2P!6 % 49 O9 G " 47? 6 %2 2< o9# %3 IUD o9#.[]278 7I N O)# %5 r7i ]7g 3"K S.` %85 r7i ]7g q S.` 7 S.` G4 OCP ]7g O9 2 f8 74 A7 49 Ob" A7#C 7Q 23k S.` 6 G4 ]7g l 7R 6 q S.` 6 7#C y`9 3"K G4.. O9 Q78 7I A7# G4 y`9 O9 297 O2B (6 o9# 2 GS# S ]7g 6 ` t O 2# < S A f8 OS 4 r7i r7i (7Å rgh < 2 7h 9 2?.[7] O9 S.` Ob" S.` G4 2< 6 * 9 G4 G3s. 7I A7# G4 y`9 3"K A46 +Q O2B (6 2 GS# S 24 2< 6 L`3 G4!6 bl 9 2 O G4!9M ) 2 9 G4 AC O".( AM HP A 6 W4 Ç S.` G4 S.`.O2 P nm 6 * G4 " nm 6 * 9 3"K

6 387! "# 6 A7 49 A 3S ab# +g h.2 A : < * 9!6 +# 23k 4 W4!6 [hc A 6 A7 A W47 2S# 479!?79 A7 7`h O*.HSV-HPV O* u6 G4 G9 "3P -(< 2-HIV) 34 "9 msc 7 A y)+ (i? 7 " # A-9 A 6 A7 A f. K (7`h A6 A7 9 6M 8M # 23 i 7`h t7s!6 A7 233< \ h S eb9 O* < 6 4 K!78!?79 n. A)!4!2.7< +# 2< 6 * 9!# (@ OB! G S.` G4.[3] S.` Ob" IUD 7 O*! P 7 S.` Ob" 7 < O9 G4 7 L 34 P# O9 7 <!M A_4P!6 IUD " A O* I ]i h G4 [7] < 7 2M 7*K IUD(W n9m 4 W n9) A_4P )!#. Ob" % ;$ G4 G39 u6! 7cK S.` Z4 A7! 7Q ( # G4) 7# 2 7I.9 (Ci h i t7s 7U O"479.9 (Ci h BBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBB A:, OK 6 W# A67? b47q A7? 2K A4 2S9 l A4 P7# - O974. 2P. Tk.É*!6 AB4 4 É* P7#.A7B !.2 # ()* ( :!7B#. 2- Mike F, Janicek MD, Hervey E. Cervical cancer: prevention, diagnosis and therapeutics. cancer J clin 2: 5:92-4. :P7#. B OS47 c7 67B 7B Ki+ 2K 24Ñ *`g U 7I 7B BP ci -3.4 # 3 ()*+ 996 } 7!7B#. 2P. {!6 A A (.!7B# 7. 2P.9 Tk.-!"4.!46!6 AB4: K7#. A # 562 ()* il!< 7B 479 (S4c!46 2S# u6 G9 ab# Q!s## !< A7 < g)#! B 2P.Bk Tk ( m.)238{-u (!6 A A P7# :76. A2) P!6 fh # 78 ()*+.373*+ (!7B#. A79 T 479 (S4c A 6 A7 9 l G ab# 97. 3"K A7 < g)#!4 -!< Az.# AB46M !7B# (;) e346 (7ÅK! 9 233< SP7 A h IUD t 97. -P ()*+ 378! " ! !6

7 55! K 8 7 <... l G ab# GS# # 77 7B 6!26 <7 N O)# A h IUD t l !26 A7 < Ä g)#! B - Barwijuk AJ, Czekanowski R. A case of pelvic actionomycosis in a woman as a complication of long- term IUD use, Ginekol Pol, 994; 65(4): MF Mitchell, WN Hittelman, WK Hong, R Lotan and D Schottenfeld. The natural history of cervical intraepithelial neoplasia: an argument for intermediate endpoint biomarkers. Cancer Epidemiology Biomarkers & Prevention, 999. Vol 3, Issue 7: B G<9 K 2c A r7i 233< ]7g # 5!6 "P o47 97.l L? ()*+ B B.! !6 ) Schwarz EB, Saint M, Gildengorin G, Weitz TA, Stewart FH, Sawaya GF. Cervical cancer screening continues to limit provision of contraception. Contraception. 25 Sep; 72(3): Saint M, Gildengorin G, Sawaya GF. Current cervical neoplasia screening practices of obstetrician/gynecologists in the US Am J Obstet Gynecolog. 25 Feb; 92(2):44-2.