1.5T HIGH FIELD SMALL ANIMAL MRI

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1 1.5T HIGH FIELD SMALL ANIMAL MRI Designed Specifically for Veterinarians TECHNICAL GUIDE

2 ADVANCING THE ART AND SCIENCE OF VETERINARY MRI The PetVet is the only high-field MRI system designed specifically for veterinarians. The Hallmarq MRI scientists are solely dedicated to making sure that its MRI machines meet the needs of veterinarians and their patients.

3 WORLD LEADERS IN VETERINARY SPECIFIC MRI SYSTEMS SUPERIOR IMAGES State-of-the-art veterinary specific 1.5T high field system V-shaped spine coil for 20-percent better signal to noise ratio Veterinary image protocols designed by MRI experts Dual coil capability for imaging difficult areas Transverse FLAIR FSE Canine Brain Sagittal T2 Canine T-L Spine LOW TOTAL COST OF OWNERSHIP No RF shielded room required Designed to be energy efficient Purchased outright or financed through a Pay-As-You-Go model to minimise a large capital investment Zero boil off cold head which means no routine helium refills EASY TO USE Does not require an MRI technologist Initial and ongoing training and support Each system is monitored every five minutes for proactive diagnosis Standardised protocols in a drop-down menu for quick selection (breed, spine, etc.) Remotely maintained by Hallmarq support team Patient monitoring via video camera 3

4 HEAD COIL V-SHAPED PATIENT BED AND COIL PetVet s unique veterinary head coil uses an elongated design to give greater coverage than a typical human head coil. The three sizes of head coils each make maximum use of the 50-cm imaging volume, giving better anatomical coverage in each scan. The head coil is particularly effective acquiring excellent images of cat spines. The V-shaped patient bed and spine coil is designed to facilitate imaging in dorsal recumbency and optimise SNR. Human spine coils are flat which is a poor fit for a dog s anatomy. FLAT PATIENT BED AND FLEX COILS INTEGRATED RF SHIELD The Hallmarq patient bed can be fitted with in-filler cushions to give a flat surface for lateral recumbency. The door closes while scans are in progress to complete the RF shield. Monitoring leads and anaesthetic tubing exit via waveguides. 4

5 WORLD LEADERS IN VETERINARY SPECIFIC MRI SYSTEMS SPECIFICATIONS OF THE PETVET 1.5T MRI FOR SMALL ANIMALS Superconducting magnet Actively shielded superconducting magnet with integrated closed cycle refrigerator system Field strength: Homogeneity (shimmed over 50cm DSV): Patient bore diameter: 1.5 Tesla (+/ Tesla) < +/- 12ppm (peak to peak) >59cm RF Filter Panel RF filter panel integrated with the magnet RF shielding Simplified coil selection box (MUX) located at the rear of the magnet RF transmit/receive switch and quadrature hybrid located at the rear of magnet RF Subsystem Helium boil-off rate: Stray field: Zero boil-off (when cryocooler is running normally) < 3.9 m (Axial), < 2.6 m (Radial) Resonant frequency: RF preamplifier: Quad combiners: 63.75MHz (+/- 0.75MHz) Integral to each coil element Integral to each coil quad pair RF amplifier power: Max. 9KW Patient Handling Manually operated dockable patient table for dorsal and lateral scanning Maximum Patient Weight: Patient Positioning: Patient table: Table height: Patient cradle: Bore lighting and ventilation Video patient monitoring 100kg Markers on patient bed and bore Dockable with v-shaped cradle Fixed with mechanical lateral movement Removable v-shaped cradle with closed ends and handles Gradient Subsystem High performance actively shielded whole body gradient coil system with integrated magnet shims Maximum amplitude: Maximum slew rate: Eddy currents 30mT/m 110mT/m/ms <0.5% at 50cm DSV (without pre-emphasis) Acoustic dampening material within the gradient assembly Gradient cooling from heat exchanger located within the cooling cabinet RF Shielding Local RF screening on the magnet RF noise attenuation >85dB RF viewing window on front and rear of magnet Lockable door on front with simple catch for door release 4 waveguides integrated on the front RF shield, each waveguide 40mm diameter CONTINUOUS ONLINE AND LIVE SUPPORT

6 RF Coils Standard coils 2 channel, transmit and receive body RF coil (>590mm internal diameter) 4 channel, large flexible RF coil (500mm x 220mm) 8 channel, medium head RF coil (360mm x 180mm, open ended) 16 channel, spine array to fit within V-shaped patient cradle (1,000mm length) 8 channel, small head coil/orthopaedic coil (140mm x 280mm, open ended) Optional coils (not included in standard contract) 8 channel flex torso coil (500mm x 440mm) 8 channel, large head RF coil (240mm x 440mm, open ended) The system is designed to allow the use of two coils simultaneously for imaging hard-to-reach locations Equipment room subsystem Four main system cabinets located within the equipment room System cabinet, including: 4 channel MRI spectrometer System computer RF amplifier Equipment room computer Magnet monitoring unit Ethernet switch Gradient amplifier cabinet Power distribution cabinet Water cooler cabinet, including: Compressor Heat exchanger Data Processing and Imaging Display (System Computer) OS: Memory: Hard disk storage: Monitor: DICOM support: Image Archival: USB keyboard and mouse Standard Software Package Windows O/S 64bit 6 GB 500GB dual drive non-raid Colour LCD flat panel DICOM 3.0, PACS USB compatible archive device Scan Sequences Spin Echo 2D FSE 2D (Single and Multiple echo) FSE Dual Echo Fast IR Gradient Echo and fast spoiled Gradient echo 2D / 3D FLAIR / STIR FLASH Fat saturation and suppression for SE, FSE and GRE DWI HASTE PDW User Selectable Options Workstation software with clinical user interface Graphically prescribed sat pulses Phase direction selection and swapping Double and Triple oblique Offset FOV Post Processing Image Subtraction Image Filtering Multi-channel image summing with intensity correction MIP Spectrometer Input frequency range: 15-64MHz Maximum RF receiver channels: 8 Transmitter: 14bit digital Receiver: 16bit digital Max sampling rate: 400 khz per channel Minimum slice thickness: 0.3mm Maximum Matrix: 1024x1024

7 WORLD LEADERS IN VETERINARY SPECIFIC MRI SYSTEMS CUSTOMISED MRI ROOM LAYOUT Hallmarq supports you through every step of the room planning and building process. Here is an example of how your MRI room could look. Call us today for a feasibility study. We will be happy to draw up a personalised room plan to show how the PetVet could fit into your practice. Standard Room '-6 10" '-7 10" '-0" '- 5" MRI Chiller Unit ( EU) Service area '-10 2" 1 Heat Exchanger System Cab AC Unit 2.6m x 2.8m high ( 8'-5" x ( 9'-2 1/4") opening in the external wall for system delivery 150 6" '-2" '- 9 2" 1 Hallmarq Pen Panel Ceiling height 3.1m (10'-2") Fire Exit Large Vehicle Exclusion zone Small Vehicle Exclusion zone Total internal area 63.5 msq (683.5sq ft) Siting and Installation Power type 3 Phase + PE + N AC Chiller unit PDU Gradient Amplifier EQUIPMENT ROOM Quench pipe runs vertically to roof '- 4 10" '-11 Main line transformer capacity Minimum 100kVA 5G MRI ROOM Coil Rack 6" 150 Voltage 380/400/415/440/ 480V AC +/- 5% AC Viewing window CONTROL ROOM '-6 10" 7 Frequency 50/60 +/- 1Hz '-0 2" '-4" '-4 10" 8 TOTAL INTERNAL AREA 63.5msq ( 683.5sq ft) Instantaneous voltage In 200ms, any one phase of voltage should be no higher or lower than 10% of the total voltage Phase equilibrium < 2% Park Ind. Est LOCATION DESCRIPTION PETVET Note: Final specifications all subject to contract. 7

8 Hallmarq Veterinary Imaging, Inc. 20 Main Street, Acton, MA 01720, USA Hallmarq Veterinary Imaging, Ltd. Unit 5, Bridge Park, Guildford, Surrey, GU4 7BF, UK +44 (0) hallmarq.net Hallmarq Veterinary Imaging Version 1.2