SCHWIND eye-tech-solutions International Distributor Meeting Friday, 16th September 2011, 3:00 6:00 p.m. Hotel Sofitel Vienna Stephansdom
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1 Trust your eyes.
2 SCHWIND eye-tech-solutions International Distributor Meeting Friday, 16th September 2011, 3:00 6:00 p.m. Hotel Sofitel Vienna Stephansdom Room: Niemeyer & Lloyd Wright
3 Rethinking Corneal Surgery The innovative SmartTech Laser
4 How the SmartTech Laser works? The SmartTech Laser works with a nanosecond pulse technology. for the cornea it makes no difference who created this plasma Equal to femtosecond lasers, the SmartTech Laser produces laserinduced plasma to separate the corneal tissue by using photodisruption. Instead of the highly complex femto laser source, an innovative ultraviolett semiconductive microchip laser is used.
5 f1 The SmartTech Laser offers a new laser technology using ultraviolet nano pulses Wavelength: SmartTech Laser UV λ~ 355nm Femto Laser IR λ~ 1040nm Pulse duration: Short pulses (< 0.8 ns = 800 ps) Ultra short pulses (< 800 fs = 0.8 ps) Pulse energy Mean Power = Pulse energy Pulse duration < 1.5 µj ~ MW µj ~ 2 MW (@1,5µJ/ 800fs)
6 Diapositiva 5 f1 pulse energy < 1,5 µj!!! (depends also on spot distance;-)) faustse1; 18/02/2011
7 The SmartTech Laser offers a new laser technology using ultraviolet nano pulses SmartTech Laser Femto Laser Tissue depth resolution: 3 times shorter wavelenght means 3 times better resolution Repetition rate: ~150 khz ~ 60 khz, 150 khz to MHz
8 The SmartTech Laser yields *NA= Numerical Aperture
9 The SmartTech Laser yields *NA= Numerical Aperture
10 The SmartTech Laser yields Simulated for same puls energy, same puls rate and for the same high NA* *NA= Numerical Aperture
11 The SmartTech Laser offers no collateral damage due to no filamentation SmartTech (UV) Standard fs-laser (IR) Too much energy destroys the tissue which is passed by Self-focusing Defocusing Plasma Self-focusing A Heisterkamp Dissertation, Univ. Hannover(2002) and C.L. Arnold et al., Appl Phys B 90, (2005)
12 The SmartTech Laser offers higher accuracy in depth due to no self-focusing effect SmartTech (UV) Ultra short pulses in gelatine with equal settings for depth, but different energies Standard fs-laser (IR) 1 µj 2 µj 3 µj LASER Self-focusing Uncontrolled Optical breakdown 3 µj Self-focusing Uncontrolled Optical breakdown 2 µj Controlled Optical breakdown 1 µj Intended tissue section
13 The SmartTech Laser offers - multiple settings and informations - optimized flap placement by an integrated pupil detection
14 The SmartTech Laser offers an innovative UV microchip laser. These lasers are compact, rugged and turnkey ready.
15 The SmartTech Laser Patient interface
16 The perfect duo The electrically swiveling patient bed offers a high comfort to the patient together with a ergonomic workplace for the surgeon
17 The perfect duo The swiveling laser arms of the SmartTech Laser and the SCHWIND AMARIS 750S minimize space requirements
18 The SmartTech Laser First cuts in porcine corneas Video
19 The SmartTech Laser First cuts in porcine corneas results flap thickness measured values nominal values 146 ± 6 µm ( ) 177 ± 6 µm ( ) 190 central flap thickn ness [µm] ± 5 µm (73-87) 122 ± 8 µm ( ) N = 1 13 N = 2 32 N = 3 8 N 4= 5
20 The SmartTech Laser First cuts in porcine corneas linearity of cutting depth measure value [µm] y = 0,9528x - 7,9548 R 2 = 0, nominal value [µm]
21 The SmartTech Laser Cuts in porcine corneas REM imaging Flap interface Prof. Dr. Alfred Vogel Side cut * A. Vogel, N. Linz, S. Freidank; Institute of Biomedical Optics UNIVERSITY OF LUEBECK
22 The SmartTech Laser Chinchilla bastard rabbit University clinic for Ophthalmology and Optometry Salzburg Experimental Ophthalmology Prim. Univ.-Prof. Dr. Günther Grabner OA Univ.-Prof. Dr. Herbert Reitsamer For the detection of morphological changes in standard histology, immunohistochemistry, electron microscopy and TUNEL assay (detection of apoptotic and necrotic cells) were performed. For the investigation of aqueous humor on inflammatory parameters were "High Sensitivity ELISA" kit used with signal amplification.
23 The SmartTech Laser Chinchilla bastard rabbit Flap creation was 100% possible RA TUNEL vertical cut vertical cut
24 The SmartTech Laser Chinchilla bastard rabbit Endothelium: closed cell structure, no chromatin condensation, no apoptosis cells Complete cornea Border of Descement and Endothelium
25 The SmartTech Laser Chinchilla bastard rabbit Lens: connection between epithelium and lens capsule and lens stroma fine, no signs for Apoptosis or Nekrosis aqueous Lens Iris Lensepithelium
26 The SmartTech Laser Chinchilla bastard rabbit Retina: all cell structures intact, no abnormalities between treated and untreated eyes Retina
27 The SmartTech Laser First cuts in human corneas results flap thickness measured values nominal values ± 8 µm ( ) central flap thickne ess [µm] ± 8 µm (83-102) N = 17 N = 2 4
28 The SmartTech Laser First cuts in human donor corneas SEM imaging Flap interface Side cut * Mr Arun Brahma, B.Sc (Hons), MB ChB (Hons), MD, FRCOphth; Manchester Centre for Vision at Manchester Royal Eye Hospital
29 f3 The SmartTech Laser Benefits at a glance No higher risk for the patient than with femto Higher resolution by using ultraviolet instead of infrared Higher precision due to no self-focusing and no filamentation Pupil detection for optimized flap placement according to excimer treatment Less collateral damage due to lower total energy Robust and mobile laser The treatment with the SmartTech Laser is a save and tissue-protecting procedure Laser is designed for corneal surgeries (starting with Flap, later more applications available by changing the software) FAQ are separately available
30 Diapositiva 28 f3 Higher precision..genau genommen noch unbekannt und wenn ist aus die Kombination aus allem (Die beugungsbegrenzte Optik mit hoher NA, die kürzerer Wellenlänge und das low density Plasma sowie unsere Algorhythmen werden zu einer hohen Präzision führen:-)!!! => Higher precision due to e.g. a diffracted limeted optic system with a high numerical apeture and also no self focusing effects!?! Less collateral damage due to lower (1000x) peak power or peak intensity!!! faustse1; 18/02/2011
31 Thank you very much for your attention Vielen Dank für Ihre Aufmerksamkeit SCHWIND eye-tech-solutions fon: +49(0)6027 / fax: +49(0)6027 / info@eye-tech.net Internet: SCHWIND eye-tech-solutions GmbH & Co. KG Mainparkstrasse Kleinostheim Germany
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