Web-based Remote Human Pulse Monitoring System with Intelligent Data Analysis for Home Healthcare

Transcription

1 We-sed Remote Humn Pulse Montorng System wth Intellgent Dt Anlyss for Home Helthcre Chh-Mng Chen Grdute Insttute of Lrry, Informton nd Archvl Studes, Ntonl Chengch Unversty, Tpe 6, Twn, R.O.C. Chn-Mng Hong Grdute Insttute of Appled Electronc Technology, Ntonl Twn Norml Unversty, Tpe 6, Twn, R.O.C. Ch-Meng Hung Grdute Insttute of Industrl Educton, Ntonl Twn Norml Unversty, Tpe 6, Twn, R.O.C. T-Hung Lee Grdute Insttute of Lernng Technology, Ntonl Hulen Unversty of Educton, Hulen 97, Twn, R.O.C. Astrct Mny studes hd ndcted tht pplyng ntellgent systems wth physology sgnl montorng for e-helth cre s current developng trend. A physology sgnl montorng system cn help medcl stffs to montor nd nlyze humn s physology sgnl effectvely, such tht they cn not only montor the ptents physology sttes mmedtely, ut lso reduce medcl cost nd sve lot of tme of ptents to vst hosptl s doctors. Therefore, the study employed system on chp (SOC) technques to develop n emedded humn pulse montorng system wth ntellgent dt nlyss mechnsm for dsese detecton nd long-term helth cre, whch cn e ppled to montor nd nlyze humn s pulse sgnl n dly lfe. Menwhle, the proposed system lso developed frendly we-sed nterfce tht s convenent to the oservton of mmedte humn physologcl sgnls. Moreover, ths study lso proposes n ntellgent dt nlyss scheme sed on the modfed cosne smlrty mesure to dgnose norml humn pulses for explorng potentl chronc dseses. Therefore, the proposed system provdes enefts n terms of dng long-dstnce medcl tretment, explorng trends of potentl chronc dseses, nd urgent stuton nformng for sudden dseses. Keywords pulse physology sgnl montorng system, emedded system, e-helth cre, sequence dt nlyss I. INTRODUCTION Wth progress of medcl technologes nd development of newer nd etter medcnes, mny countres re grdully comng nto gertrc socetes due to rpd growth of the gng populton, such tht the requrement of home helth montorng hs een ncresngly rsed for securng ndependent lves of elder or ged ptents []. Prtculrly, dvncements of physologcl sensors, wreless communctons, nd nformton technologes hve resulted n the rpd development of vrous wellness or dsese montorng systems, whch enle extended ndependent lvng t home nd mprovement of qulty of lfe for ndvduls [2]. Mny studes [2] [3][4] hd ndcted tht montorng humn physologcl nformton n rel-lfe condtons s especlly useful n mngement of chronc dsorders or helthcre prolems. Importntly, performng long-term montorng process s helpful to provde follow-up dt to oserve long-term trends n the wellness or helth sttus. In the pst yers, mny reserches pd much ttenton on developng long-term helth-cre montorng systems [5][6], whch re requred to e compct, lghtweght, low power consumpton, low-cost nd comfortle to e used t nytme. Furthermore, they must e le to detect physologcl sgnls relly nd stly n vrous dsturnces. Most of the reserches for helth-cre montorng n out-of-hosptl envronment hve concentrted on helth montorng t home [2][3][5][6][7][8]. Furthermore, there re reserch trends towrds developng werle physologcl montorng systems tht cn mesure vrous o-sgnls nd provde helthcre servces to user usng e-helth technology [7][8]. Moreover, the concept of remote montorng vtl sgnl y we-sed nterfce [9][], whch s helpful to trnsmt mmedte physologcl prmeters to physcns who re cple of nterpretng the mesurements for ndvduls, s lso key ssue for physologcl sgnl montorng systems. It s not only convenent to ndvduls who re ctvely wllng to receve feedck regrdng hs/her wellness or dsese sttus nd to prtcpte n hs/her own cre, ut lso provdes the eneft of dstnce tretment. Among humn vtl sgnls, ssessment of humn pulse hs long een reserch re of nterest n the physology feld ecuse the stutons of humn pulse reflect mny helth sttes [][2]. Humn pulse s the rte t whch humn hert ets. Therefore, humn pulse s usully clled hert rte, whch s the numer of tmes your hert ets ech mnute. However, the rhythm nd strength of the hertet cn lso e noted, s well s whether the lood vessel feels hrd or soft. Chnges n your hert rte or rhythm, wek pulse, or hrd lood vessel my e cused y hert dsese or nother prolem. Bsed on the mportnce of montorng humn pulse, the study med to develop novel we-sed remote humn pulse montorng system wth ntellgent dt nlyss sed on physologcl sensor, SOC (system on chp), wreless communcton, World Wde We, nd ntellgent dt nlyss technologes, for wellness montorng nd homecre. The mn emphss ws on uldng hndheld SOC-sed humn pulse montorng system, whch ntegrted wth wred home Internet network to trnsmt physologcl sgnls to remote physologcl nformton dtse through wreless communcton nterfce on SOC pltform. The proposed system lso developed frendly we-sed nterfce tht s convenent to the oservton of mmedte humn /8 /$ IEEE CIS 28

2 physologcl sgnls to support dstnce tretment. In ddton, ths study lso proposes n ntellgent dt nlyss scheme sed on the modfed cosne smlrty mesure to dentfy the smlrtes etween ny two humn pulse sequences. The proposed scheme s helpful to dgnose norml humn pulses for explorng potentl chronc dseses. II. SYSTEM DESIGN Ths secton ntroduces the system desgn sed on physologcl sensor, sgnl preprocessng, emedded system, wreless communcton, nd World Wde We technologes. A.. System Archtecture Ths study presents we-sed remote humn pulse montorng system whch s composed of three prts ncludng the pulse sgnl mesurng module, the ARM emedded system pltform nd the remote server. Fgure presents the system rchtecture of the proposed system. The pulse sgnl mesurng module ms to sense the humn pulse sgnls v the pezoelectrc sensor nd to perform the sgnl preprocessng process for flterng out nosy sgnl. To trnsfer humn pulse sgnls to the emedded system, the nlog humn pulse sgnls re frst trnsferred nto dgtl sgnls y nlog-dgtl converter, nd then trnsmt to the emedded system through serl trnsmsson devce under predefned ud rte. When the collected humn pulse dt meet the predetermned mount, the emedded system trnsmts the humn pulse dt to the remote server y wreless communcton. Fnlly, the remote server stores the sensng humn pulse sgnls nto humn physology dtse s well s shows the physology sgnls to medcl personnel through we nterfce. The we-sed nterfce provdes eneft n terms of on-lne remote medcl dgnoss for home-helth cre. Furthermore, ths study presents n ntellgent dt nlyss scheme sed on symolc-sed hmmng dstnce smlrty mesure to detect norml humn pulse for home-helth cre. B. The Employed Scheme for Computng the Humn Pulse Rte Snce the humn pulse sgnl s smlr to the electrocrdogrm (ECG) sgnl, the rel-tme QRS detecton lgorthm [3] ws ppled to compute the humn pulse rte n ths study. The lgorthm cn detect the poston of R-wve, nd then use the ntervl tme etween ny two R-wves to compute the humn pulse rte. Fgure 2 llustrtes the detled procedures of estmtng humn pulse rte. The computng procedures nclude dfferenttng, squrng, movng-wndow ntegrton, flterng out the sgnl elements tht ther voltge levels re 2/3 low thn the hghest voltge level, computng ntervl tme etween ny two R-wves, nd estmtng humn pulse rte. Next, ths study gves n exmple to expln how to estmte humn pulse rte y the employed rel-tme QRS detecton lgorthm. Frst, Fg. 3 shows the orgnl pulse sgnl otned from the sgnl preprocessng crcut. Bsed on the rel-tme QRS detecton lgorthm, the orgnl humn pulse sgnl must e frst dfferentted to otn the slope nformton. Fgure 4 depcts the dfferentted result of the humn pulse sgnl. After performng dfferentton operton, the humn pulse sgnl s squred to emphsze the slope of the R-wve. Fgure 5 shows the humn pulse sgnl fter performng squrng operton. The next process s to perform the movng-wndow ntegrton operton. The movng-wndow ntegrton ms to flter out the nose ner the R-wve. Fgure 6 revels the humn pulse sgnl fter performng movng-wndow ntegrton operton. To preserve useful sgnl elements for computng humn pulse rte, the other sgnl elements should e fltered out excludng R-wve. Fgure 7 shows the humn pulse sgnl tht flters out the sgnl elements tht ther voltge levels re 2/3 low thn the hghest voltge level. Fnlly, the humn pulse rte cn e computed ccordng to the tme ntervl etween ny two R-wves. The humn pulse rte cn e estmted y the followng formul: f h = 6 () td where f h s the humn pulse rte, nd t d s the ntervl tme etween ny two turnng ponts. Fg.. System rchtecture of the proposed we-sed remote humn pulse montorng system Orgnl humn pulse sgn Dfferenttng humn pulse sgnl Squrng humn pulse sgnl Performng movng-wndow ntegrton operton Computng hert rte Fg. 2. The computng procedure of humn pulse rte Flterng out the voltge level s 2/3 low thn the hghest voltge level Computng the tme ntervl etween ny two R-wves

3 Fg. 3. The orgnl humn pulse sgnl Fg. 5. The humn pulse sgnl fter performng squre operton Fg. 4. The humn pulse sgnl fter performng dfferentton operton Fg. 6. The humn pulse sgnl fter performng movng-wndow ntegrton operton Fg. 7. The humn pulse sgnl tht flters out the sgnl tht ts voltge level s 2/3 low thn the hghest voltge level C. The Proposed Modfed Cosne Smlrty Mesure for Identfyng Anorml Humn Pulse Sequence Frst, n order to dentfy norml humn pulse sequence usng the proposed modfed cosne smlrty mesure, the symolc trnsformton ws used to represent humn pulse sgnl n ths study. The mjor concept s to trnsfer the humn pulse sgnl wth numercl dt type nto the humn pulse sgnl wth symolc dt type y ssgnng correspondng symol to ech smplng humn pulse sgnl. The prmry dvntge of the symolc trnsformton s to reduce the computtonl complexty of dentfyng norml humn pulse sequence, ut ths trnsformton could lose the orgnl chrcter of humn pulse sgnl. Therefore, ths study employs the slope trnsformton to dentfy the orgnl fetures of humn pulse sgnl efore performng the symolc trnsformton. After trnsformng the humn pulse sgnl nto the symolc dt sequence, the proposed modfed cosne smlrty mesure s ppled to estmte the smlrty degree etween ny two symolc sequences for dentfyng norml humn pulse sequences. Next, the slope nd symolc trnsformtons re detled s follows: (A) Slope trnsformton In order to dentfy the fetures of humn pulse sgnl for trnsferrng n orgnl humn pulse sgnl nto symolc dt sequence, the slope trnsformton s frst operted efore performng symolc trnsformton n the study. Suppose tht the sequence S = { s, s2,..., s,..., s m } represents m smplng humn pulse sgnl ponts, nd the sequence T = { t, t2, t3,..., t,..., t m } s ech correspondng smplng tme. The slope trnsformton cn e performed y the followng mthemtcl formul: s s + S =, m (2) t+ t where S = { s, s 2, s 3,..., s,..., s m } stnds for the trnsformed humn pulse sequence, s s the th smplng humn pulse sgnl pont, t s the correspondng smplng tme of the th humn pulse sgnl pont, nd m represents the totl numer of smplng humn pulse sgnl ponts. (B) Symolc trnsformton After performng the slope trnsformton, the vred sttuses of humn pulse sgnl re successfully extrcted for symolc trnsformton. There re two fctors tht need to e consdered when performng symolc trnsformton: one s how mny symolc chrcters should e used, nd nother s how much nformton of the humn pulse sgnl could e lost under usng lmted symolc chrcters for symolc trnsformton. Actully, these two consdertons re trde-off ssue. More symolc chrcters hve to e used f more complete humn pulse nformton need to e preserved, ut such symolc trnsformton wll ncrese the computtonl complexty of dentfyng norml humn pulse sgnls. Conversely, usng less symolc chrcters wll lose some humn pulse nformton, ut t cn reduce the computtonl complexty of dentfyng norml humn pulse sgnls. To mke ll smplng ponts of humn pulse sgnl tht hve performed the slope trnsformton ecomng comprtve sequences to ech other, the z-score normlzton must e frst conducted efore performng the symolc trnsformton. The z-score normlzton s formulted s follows: s s s = ' σ (3) where s stnds for the th humn pulse sgnl wth z-score th normlzton, s s the humn pulse sgnl wth ngulr trnsformton, s s the men of the humn pulse sgnls wth ngulr trnsformton, nd σ ' s the stndrd devton of the humn pulse sgnls wth ngulr trnsformton. The humn pulse sequence tht performs the z-score normlzton hs three propertes: the men s zero, the stndrd devton s one, nd ll humn pulse dt form norml dstruton. TABLE I dsplys the cut-pont of the norml dstruton sed on vrous trnsformton symols. In

4 TABLE I, the cut-ponts prtton the norml dstruton functon s severl non-overlpped res wth equl prolty. For exmple, two cut-ponts.43 nd.43 prtton the norml dstruton functon nto three non-overlpped res, nd ech re hs /3 occurrence prolty. TABLE I THE CUT-POINT OF THE NORMAL DISTRIBUTION BASED ON VARIOUS TRANSFERRED SYMBOLS The numer of Cut-pont trnsformton symols 3 (-.43,.43) 4 (-.67,,.67) 5 (-.84, -.25,.25,.84) 6 (-.97, -.43,,.43,.97) 7 (-.7, -.57, -.8,.8, -.57, -.7) 8 (-.5, -.67, -.32, -.4,.4,.32,.67,.5) 9 (-.22, -.76, -.43, -.4,.4,.43,.76,.22) (-.28, -.84, -.52, -.25,,.25,.52,.84,.28) (C) The proposed modfed cosne smlrty mesure for dentfyng norml humn pulse sgnl To dentfy norml humn pulse sgnl, ths study employs the cosne smlrty mesure to compute the smlrty degree etween ny two humn pulse sequences. Suppose tht the unon symols set otned from the humn pulse sequence P nd the humn pulse sequence P contns totl of k symolc terms. The smlrty degree etween two humn pulse sequences mesured y the cosne mesure cn e formulted s k s s Sm( P, P ) = (4) 2 s = k k 2 s = = where P = ( s s s,..., s ) nd P = ( s s s,..., s ),,..., 2 k, 2,..., represent respectvely the symol vectors of the humn pulse sequence P nd the humn pulse sequence P, s nd s stnd for the symol weghts of the th symol n the humn pulse sequence P nd the humn pulse sequence P, respectvely. In Eq. (4), the correspondng symol weght n the symol vector s computed sed on the symol frequency tht ppers n humn pulse sequence. However, the cosne smlrty mesure cnnot dentfy the smlrty degree etween ny two humn pulse sequences well, ecuse t cnnot completely revel humn pulse symolc semntcs. For exmple, the smlrty degree of the humn pulse sequence ABCD nd DCBA mesured y cosne mesure s equl to snce oth the humn pulse sequences nclude the sme set of symolc terms. Ths smlrty degree evluted y cosne mesure mples tht oth humn pulse sequences re completely dentcl n terms of semntcs, ut they hve completely dfferent menngs from the perspectve of humn pulse sgnl. In other words, the humn pulse symol tht ppers t dfferent postons represents dfferent menng. k To consder symol s poston for promotng the ccurcy when dentfyng norml humn pulse sequences, the proposed hmmng dstnce ws ppled to modfy the cosne mesure for mesurng the smlrty degree etween two humn pulse sequences wth ncresed precson. The proposed hmmng dstnce for oth the humn pulse sequences cn e computed usng the followng formul: H m P P = where L ( s ) nd ( s ) ( s ) L( s ) = L (5), L represents respectvely the trnsformed locton ndex vlues of the th symol tht ppers smultneously n the symol sequences of oth the humn pulse sequence P nd humn pulse sequence P, m s the totl numer of symols tht pper smetneously n the symol sequences of oth the humn pulse sequence P nd the humn pulse sequence P. To consder oth smlrty degree nd symol sequence semntcs smultneously when dentfyng norml humn pulse sequences, the modfed cosne mesure s expressed s H P, P Msm( P, P ) = ( ) Sm( P, P ) Mx( H ) (6) where Mx (H ) represents the mxmum hmmng dstnce mong the humn pulse sequence P wth ll dentfyng humn pulse sequences. Next, ths study gves n exmple to expln how to compute the hmmng dstnce etween two humn pulse sequences. Suppose tht the humn pulse sequence P contns four symolc terms fter performng symolc trnsformton, nd the symolc term set of the humn pulse sequence P s represented s P = { s, s2, s4}. To compute hmmng dstnce, term set P must e trnsformed nto locton vector sed on the order n whch symols pper. For exmple, the trnsformed locton vector of symolc term set P s represented s L ( P ) = (,2,3,4 ) for the correspondng symolc term set P = { s, s2, s4}. Moreover, suppose tht the symolc term sets of nother two humn pulse sequences P nd P re c P = { s, s5} nd P c = { s, s5, s3}, respectvely. Smlrly, the trnsformed locton vectors for oth P nd P re c L( P ) = (,2,3) for symolc term sets P = { s, s5}, s well s L( P c ) = (,2,3 ) for symolc term set P c = s, s, }. Therefore, the hmmng dstnces { 5 s3 etween the humn pulse sequence events P nd P c cn e computed s P H, = = P P wth the news

5 H, = = P P c III. EXPERIMENTS Currently, the proposed we-sed remote humn pulse montorng system ws mplemented on n emedded system wth Lnux operton system. The Apche we server, PHP lnguge, nd MySQL dtse were employed to develop the server sde system. Ths secton revels the mplemented we-sed remote humn pulse montorng system nd demonstrtes the performnce of the proposed modfed cosne smlrty for explorng norml humn pulses. A. The Implemented We-sed Remote Humn Pulse Montorng Fgure 8 shows the mplemented we-sed remote humn pulse montorng system, whch ncludes the pulse trnsducer pezoelectrc sensor for sensng humn pulse sgnl, sgnl preprocessng crcut for flterng our nosy sgnl nd mplfyng wek humn pulse, ARM emedded system wth Lnux operton system for trnsmttng humn pulse nto we server y wreless networks, we server wth humn physology dtse for collectng mmedte humn pulse sgnl, osclloscope for verfyng the qulty of sensng humn pulse sgnl, nd power supply. Usng ths system, medcl stffs cn drectly oserve humn pulse sgnl y we rowser from ny plce. Ths provdes enefts n terms of long-dstnce medcl tretment, explorng trends of potentl chronc dseses, nd urgent stuton nformng for sudden dseses. To verfy the mplemented system cn correctly mesure humn pulse sgnls, Fg. 9 smultneously shows humn pulse sgnl on oth the we nterfce nd osclloscope. Except dsplyng mmedte humn pulse sgnl, the we nterfce cn lso dsply the correspondng hert rte. Ths study confrmed tht the humn pulse sgnl dsplyed on the osclloscope s the sme wth the humn pulse sgnl dsplyed on the we rowser. Fg. 8. The mplemented we-sed remote humn pulse montorng system Fg. 9. The humn pulse sgnl smultneously dsplyed on oth the we nterfce nd osclloscope B. Explorng Anorml Humn Pulse y the Proposed Modfed Cosne Smlrty Mesure To demonstrte whether the proposed modfed cosne smlrty mesure cn correctly explore norml humn pulses, ths study mesured fve ctul humn pulse sgnls from fve dfferent persons to compre ther smlrtes to ech other y the cosne smlrty mesure nd the proposed modfed cosne smlrty mesure. Ths experment ms to demonstrte tht the proposed modfed cosne smlrty mesure cn correctly explore two most smlr humn pulse ptterns to ech other from humn pulse physologcl dtse. Ths wll e helpful to judge whether sensng humn pulse s smlr to ny norml humn pulses stored n humn pulse physologcl dtse. Fg. shows fve humn pulse sgnls sensed from fve dfferent persons. To compute smlrtes etween ny two humn pulses, the symolc trnsformton must e frst performed. Ths study dopted ten symolc chrcters to represent the orgnl humn pulse s symolc dt sequence y the proposed symolc trnsformton process. TABLE II shows the result of symolc trnsformton. TABLE III nd IV show the smlrtes mesured y the cosne mesure nd the proposed modfed cosne mesure, respectvely. The expermentl result lsted n TABLE III ndctes tht the humn pulse (.e. dt ) s most smlr to the humn pulse 4 (.e. dt 4). However, Fg. ovously shows tht the humn pulse s most smlr to the humn pulse 3 (.e. dt 3) n ths cse, not the humn pulse 4. The expermentl result lsted n TABLE IV confrms tht the proposed modfed cosne smlrty mesure cn correctly dentfy ths prolem ecuse the poston semntcs of humn pulse sequence nd symolc ppernce frequency re smultneously consdered. IV. CONCLUSIONS Ths study presents We-sed remote humn pulse montorng system wth ntellgent dt nlyss sed on physologcl sensor, SOC (system on chp), wreless communcton, World Wde We, nd ntellgent dt nlyss technologes for home helthcre n dly lves. The proposed system not only cn correctly sense nd trnsmt humn pulse

6 sgnls to humn physologcl dtse n server sde, ut lso provde frendly we-sed nterfce tht s convenent to the oservton of mmedte humn physologcl sgnls nd hert rte to support dstnce tretment n clent sde. In ddton, ths study lso presents modfed cosne smlrty mesure, whch cn dentfy norml humn pulse sequences, to support explorng potentl chronc dseses. More mportntly, the proposed system ws successfully mplemented y emedded system technology. Ths provdes enefts n terms of developng compct, lghtweght, low-cost nd hnd-held physology montorng system dt dt2 dt3 dt4 dt Fg.. T The humn pulse sgnls sensed from fve persons TABLE II. THE SYMBOLIC TRANSFORMATION RESULTS OF THE HUMAN PULSE DISPLAYED IN FIG. Elements Dt A G J J J J H E F G E E C B C B F G G G F E Dt2 B J I J J J I E H B E I B E B C E H E E E E Dt3 A G J J J I G E D E F C C B C C D D F F E E Dt4 E J J J J I H F H H E C B B C D E F E F E E Dt5 B I J J J H G E E H G D B D D D E E G D E G Elements Dt D D D D E E E E F E E E E E F E D C A A B I Dt2 E E H C C C H C E E C E H I C C C C A A A E Dt3 F D D E D D E E E E F E E E E F D C A A B I Dt4 E E F F E D F E F G E F F F F F F E D A A A Dt5 E B D E E E D D G G D E E E E E E D A A B J TABLE III. THE SIMILARITIES MEASURED BY THE COSINE MEASURE Dt Dt(R) TABLE IV. THE SIMILARITIES MEASURED BY THE MODIFIED COSINE MEASURE Dt Dt(R) REFERENCES [] Stefnov D.H., Zeungnm Ben, Won-Chul Bng, The Smrt House for Older Persons nd Persons Wth Physcl Dsltes: Structure, Technology Arrngements, nd Perspectves, IEEE Trnsctons on Neurl Systems nd Rehltton Engneerng, vol. 2, ssue 2, pp , 24. [2] Korhonen I., Prkk J., Vn Gls M., Helth Montorng n the Home of the Future, IEEE Engneerng n Medcne nd Bology Mgzne, vol. 22, ssue 3, pp , 23. [3] Mlln J., Prk S.-E., Kefer S. nd Meyer J-U., TOPCARE-Implementton of Telemtc Homecre Pltform n Coopertve Helth Cre Provder Networks, The Second Jont EMBS/BMES Conference, pp , 22. [4] Vrshney U., Mngng Wreless Helth Montorng for Ptents wth Dsltes, IT Professonl, vol. 8, Issue 6, pp. 2-6, 26. [5] Yu Y., Ou J., Desgn of Wreless Intellgent Sensor for Structurl Helth Montorng, Interntonl Conference on Intellgent Sensors, Sensor Networks nd Informton Processng, pp. -5, 4-7 Dec. 24. [6] Srovnl Vlem, nd Penhker Mrek, Helth Mntennce Emedded Systems n Home Cre Applctons, The Second Interntonl Conference on Systems (ICONS), pp. 7-7, 27. [7] Brnes G. & Wrren S., A Werle, Bluetooth-Enled System for Home Helth Cre, Proceedngs of the Second Jont EMBS/BMES Conference, vol. 3, pp , 22. [8] Jnchu Yo, Schmtz R., nd Wrren, S., A Werle -of-cre System for Home Use Tht Incorportes Plug-nd-Ply nd Wreless Stndrds, IEEE Trnsctons on Informton Technology n Bomedcne, vol. 9, no. 3, pp , 25. [9] Kong K.Y., Ng, C.Y., Ong, K., We-Bsed Montor of Rel-Tme ECG Dt, Computers n Crdology, pp , 2. [] Drs P., Bechtss D.K., Strntzs M.G., A We/WAP-sed System for Remote Montorng Ptents wth Dt Mnng Support, The 6th Semnr on Neurl Network Applctons n Electrcl Engneerng, 22. [] Lu O. nd Chwng A., Reltonshp etween Wrst-Pulse Chrcterstcs nd Body Condtons, In Proc. of the 4th Engneerng Mechncs Conf., 2. [2] Josh A.J., Kulkrn A. V., Chndrn S., Jyrmn V. K., Kulkrn B. D., Nd Trngn: A Pulse Bsed Dgnostc System, The 29th IEEE-EMBC Conf., pp , 27. [3] Pn J. & Tompkns W.J., A Rel-Tme QRS Detecton Algorthm, IEEE Trnsctons on Bomedcl Engneerng, vol. 32, no. 3, pp , 985.