Worldwide practice of breast MRI: insights from the MIPA study applications - the MIPA study group

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1 Worldwide practice of breast MRI: insights from the MIPA study applications - the MIPA study group Poster No.: B-0757 Congress: ECR 2015 Type: Scientific Paper Authors: G. Di Leo, R. M. Trimboli, I. Ioan, L. A. Carbonaro, T. H Helbich, F. Gilbert, N. Houssami, F. Sardanelli ; San Donato Milanese/IT, Milan/IT, Vienna/AT, Rotterdam/NL, Sydney/AU Keywords: Breast, MR, Statistics DOI: /ecr2015/B-0757 Any information contained in this pdf file is automatically generated from digital material submitted to EPOS by third parties in the form of scientific presentations. References to any names, marks, products, or services of third parties or hypertext links to thirdparty sites or information are provided solely as a convenience to you and do not in any way constitute or imply ECR's endorsement, sponsorship or recommendation of the third party, information, product or service. ECR is not responsible for the content of these pages and does not make any representations regarding the content or accuracy of material in this file. As per copyright regulations, any unauthorised use of the material or parts thereof as well as commercial reproduction or multiple distribution by any traditional or electronically based reproduction/publication method ist strictly prohibited. You agree to defend, indemnify, and hold ECR harmless from and against any and all claims, damages, costs, and expenses, including attorneys' fees, arising from or related to your use of these pages. Please note: Links to movies, ppt slideshows and any other multimedia files are not available in the pdf version of presentations. Page 1 of 28

2 Purpose Preoperative Breast MRI in Clinical Practice: Multicenter International Prospective Meta-Analysis (MIPA) of Individual Woman Data An EIBIR-EuroAIM/EUSOBI Study The MIPA study is an ongoing observational individual-patient data meta-analysis. We present data provided during the initial phase for center selection. Fig. 1: 1 References: Unit of Radiology, IRCCS Policlinico San Donato - San Donato Milanese/ IT Page 2 of 28

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16 Methods and materials Managing structure: European Institute for Biomedical Imaging Research (EIBIR) / European Network for Assessment of Imaging in Medicine (EuroAIM) - A structure of the European Society of Radiology Principal Investigator: Francesco Sardanelli, University of Milan - IRCCS Policlinico San Donato, EuroAIM Director Data manager at the Central Unit in Milan: Giovanni Di Leo, Rubina Manuela Trimboli, IRCCS Policlinico San Donato Scientific Advisor: Nehmat Houssami, University of Sydney Steering Committee: Francesco Sardanelli, Thomas Helbich, Fiona J. Gilbert, Nehmat Houssami, Giovanni Di Leo The MIPA study is an independent research, endorsed by the European Society of Breast Imaging (EUSOBI). All data will be property of the EIBIR/EuroAIM. The project is supported by a research grant by Bayer Healthcare#Medical Care#Radiology and Interventional In 2012, an international call was open for application. Centers described their breast MRI practice, including magnetic field strength, use of T2-weighted or DWI sequences, technical details, number of MRI examinations and number of MRI-guided biopsies performed yearly, and indications. Data were presented as median and percentiles. Page 16 of 28

17 Fig. 2: 2 References: Unit of Radiology, IRCCS Policlinico San Donato - San Donato Milanese/ IT Results We received 97 applications from Europe (n=71), Asia (n=13), South America (n=7), North America (n=2), Australia (n=2), and Africa (n=2). Magnetic field strength was 1 T in one center (1%), 1.5 T in 52 (55%), 3.0 T in 15 (16%), 1.5 T plus 3.0 T in 26 (27%), and 7 T in one (1%). All centers use a T2-weighted sequence, 16 of these (17%) STIR; 2 65/92 (71%) add DWI. Spatial resolution of dynamic study (pixel, mm ) 0.80 (0.64#1.00); #2.25 in only 4 centers (7%). Slice thickness (mm) was 1.5 ( ); #3 in nine centers (10%). Time resolution (s) was 67 (58-89). Number of breast MRI performed yearly 439 ( ); #1000 in 17 centers (18%). Centers offered MR-guided biopsy and performed 12 (2-24) procedures per year. Page 17 of 28

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26 Fig. 11: 11 References: Unit of Radiology, IRCCS Policlinico San Donato - San Donato Milanese/ IT Conclusion Most applications came from high-volume state-of-art centers using standardized hightemporal and spatial resolution dynamic technique; more than 70% add DWI. More than 40% of centers have 3-T magnets. Page 26 of 28

27 Fig. 12: 12 References: Unit of Radiology, IRCCS Policlinico San Donato - San Donato Milanese/ IT Personal information References Sardanelli F, Boetes C, Borisch B, Decker T, Federico M, Gilbert FJ, Helbich T, Heywang#Köbrunner SH, Kaiser WA, Kerin MJ, Mansel RE, Marotti L, Martincich L, Mauriac L, Meijers#Heijboer H, Orecchia R, Panizza P, Ponti A, Purushotham AD, Regitnig P, Del Turco MR, Thibault F, Wilson R. Magnetic resonance imaging of the breast: recommendations from the EUSOMA working group. Eur J Cancer May;46(8):1296# Page 27 of 28

28 Preoperative Breast MRI in Clinical Practice: Multicenter International Prospective Meta-Analysis (MIPA) of Individual Woman Data An EIBIR-EuroAIM/EUSOBI Study Page 28 of 28