UNIVERSITY OF ZAGREB SCHOOL OF MEDICINE. Plan of the course. Physiology. Academic year 2017/2018. doc. dr. sc. Vladiana Crljen

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1 UNIVERSITY OF ZGRE SCHOOL OF MEDICINE Plan of the course Physiology cademic year 2017/2018

2 I. COURSE IMS The overall aim of the Physiology course is to increase understanding of the fundamental mechanisms of how cells, and organ systems function and are regulated under normal physiological conditions but also in how their function is changed in pathological conditions, since some diseases could arise directly from abnormalities in their regulation. Lecture hours: 24 hours: 96 Practical hours: 50 Total hours: 170 ECTS 21.0 II. COURSE STRUCTURE Course hours: Lectures: 24 : 96 Practicum: 50 Total hours: 170 Physiology curriculum is organized into learning units based on major body systems and functions as: Cell, muscle physiology, cardiovascular physiology, respiratory physiology, physiology of flying and diving, renal physiology, gastrointestinal physiology, metabolism and thermoregulation, physiology of the endocrine system, physiology of the pregnancy and lactation, fetal and newborn physiology, physiology of the sport. III. PLN OF THE COURSE ND COURSE SCHEDULE LOCKS OF THE COURSE Number of blocks: 1 lock number Start End LOCKS OF THE COURSE Number of blocks: 1 lock number Start End LOCKS OF THE COURSE SHEME lock 1

3 Date Time Group Course hours type Theme 09:00-15:00; Nova Exam EXM vijećnica Monday Wednesday Friday Monday :00-08:45; 08:45-10:15; 10:15-12:30; 12:45-15:00; 08:30-10:45; Kompjutorska učionica 11:15-13:30; 14:00-16:15; Kompjutorska učionica 08:30-10:45; 11:00-13:15; Kompjutorska učionica 14:00-16:15; Kompjutorska učionica 08:00-08:45; 09:00-11:15; 11:30-13:45; Kompjutorska učionica Kompjutorska učionica Exam INTRODUCING THE PHYSIOLOGY COURSE Lectures S1 - CELL S1 - CELL L1 - INTORDUC TION and MEMRNE TRNSPORT Practicum P1 - MEMRNE POTENTIL part 1 S2 - MUSC LE Practicum P1 - MEMRNE POTENTIL part 1 S2 - MUSC LE Practicum P1 - MEMRNE POTENTIL part 2 Practicum P1 - MEMRNE POTENTIL part 2 Lectures S3 - HERT I S3 - HERT I S4 - HERT II L2 - INTORDUCING CRDIOVSCULR SYSTEM Teaching staff Kelava dr. sc. lan Šućur, Nikola Habek, dr. med., doc. dr. sc. Tomislav Kelava dr. sc. Hrvoje Lalić, Darja Flegar, dr. med., izv. prof. dr. sc. Kelava, dr. sc. Hrvoje Lalić, Darja Flegar, dr. med., dr. sc. lan Šućur, Nikola Habek, dr. med. S4 - HERT II dr. sc. Hrvoje Lalić S5 - ECG S5 - ECG

4 Date Time Group Course hours type Theme Wednesday Friday Monday :30-13:30; I 13:30-16:30; I 08:30-10:00; 10:15-12:30; 12:45-15:00; 13:00-16:00; 15:15-17:30; 10:30-11:15; 11:30-13:45; 09:00-11:15; 11:30-13:45; 14:30-17:30; Practicum P2 - ECG, RR Practicum P2 - ECG, RR Lectures L3 - INTRODUCING CIRCULTION; LPLCE LW S6 - CIRCULTION I- rterial pressure and circulation S6 - CIRCULTION I- rterial pressure and circulation S7 - MIC ROC IRC ULTION Practicum P5 - PLETISMOGRPHY, POLYGRPHY S7 - MIC ROC IRC ULTION S8 - CIRCULTION III-CO & venous return, spec.org. circulation Lectures L4 - UTONOMIC NERVOUS SYSTEM S8 - CIRCULTION III - CO & venous return, spec.org. circulation S9 - CIRCULTION II Regulation of arterial pressure S9 - CIRCULTION II Regulation of arterial pressure Practicum P5 - PLETISMOGRPHY, POLYGRPHY 10:30-12:00; Lectures L5 - LOOD C LOTTING 12:15-14:30; I Practicum P4 - LOOD C LOTTING 14:45-17:00; I 08:30-10:00; Practicum P4 - LOOD C LOTTING S10 - INTEGRTION I Teaching staff leksandra, Nikola Habek, dr. med., Kelava Darja Flegar, dr. med., Nikola Habek, dr. med., dr. sc. Vilma Dembitz Kelava Kelava leksandra dr. sc. Hrvoje Lalić, Kelava, Nikola Habek, dr. med. leksandra doc. dr. sc. Marija Renić Kelava, dr. sc. lan Šućur, Darja Flegar, dr. med., dr. sc. Vilma Dembitz, Nikola Habek, dr. med. dr. sc. Vilma Dembitz, dr. sc. lan Šućur, Darja Flegar, dr. med.

5 Date Time Group Course hours type Theme Wednesday Friday Wednesday Friday Monday :30-12:00; 08:30-12:15; S10 - INTEGRTION I Practicum P3 - ERYTHROCYTE COUNT, Ht, Hb 13:00-16:45; Practicum P3 - ERYTHROC YTE C OUNT, Ht, Hb 13:00-13:45; Č ačković 13:00-13:45; 08:30-09:30; Č ačković 08:30-09:30; Nova vijećnica 11:00-12:30; 08:30-10:45; Mašek 11:00-13:15; S10 - INTEGRTION I (CELL and CVS)/TEST S10 - INTEGRTION I (CELL ND CVS)/TEST Exam C OLLOQUIUM P1 Exam C OLLOQUIUM P1 Lectures L6 - INTRODUC TION RESPIRTORY SYSTEM S11 - RESPIRTION I - Pulmonary ventilation and circulation S11 - RESPIRTION I - Pulmonary ventilation and circulation 14:00-17:00; Practicum P6 - SPIROMETRY 11:45-14:00; 14:30-17:30; Practicum P6 - SPIROMETRY 08:30-10:45; 11:00-12:30; 12:45-15:00; 08:30-10:00; 12:00-13:30; S12 - RESPIRTION II - Principles of gas exchange; CO2 & O2 transport S12 - RESPIRTION II - Principles of gas exchange; CO2 & O2 transport S13 - RESPIRTION III - Regulation of respiration Lectures L7 - FLYING ND DIVING S13 - RESPIRTION III - Regulation of respiration S14 - INTEGRTION II S14 - INTEGRTION II Teaching staff leksandra, doc. dr. sc. Tomislav Kelava, Nikola Habek, dr. med., Kelava, Darja Flegar, dr. med. dr. sc. lan Šućur Kelava, dr. sc. Hrvoje Lalić, Darja Flegar, dr. med., Kelava, Nikola Habek, dr. med. leksandra

6 Date Time Group Course hours type Theme Wednesday Friday Monday Wednesday :15-09:00; iološka 08:15-09:00; 12:00-13:30; 10:30-13:30; I 14:00-16:15; 08:00-11:00; I 11:15-13:30; 14:00-16:15; 09:00-10:30; Mašek 10:45-12:15; Mašek 10:00-10:45; Č ačković 10:00-10:45; Nova vijećnica 13:00-14:30; Č ačković 13:00-14:30; Nova vijećnica 15:00-16:30; Č ačković S14 - INTEGRTION II (Respiratory system)/test S14 - INTEGRTION II (Respiratory system)/test Lectures L9 - INTRODUC ING RENL SYSTEM S15 - ODY FLUIDS S15 - ODY FLUIDS S16 - KIDNEY I - Structure, GFR, Clearance S16 - KIDNEY I - Structure, GFR, Clearance S17 - KIDNEY II-Tub trans.&proc.,reg.of K,C a,hpo4&mg Practicum P7 - PROLEM SOLVING S17 - KIDNEY II-Tub trans.&proc.,reg.of K,C a,hpo4&mg Practicum P7 - PROLEM SOLVING S18 - KIDNEYIII-Regulation of ECV & osmolarity, Urine concetration S18 - KIDNEYIII-Regulation of ECV & osmolarity, Urine concentration S19 - CID SE LNCE S19 - CID SE LNCE S20 - INTEGRTION III S20 - INTEGRTION III S20 - INTEGRTION III (Renal system)/test S20 - INTEGRTION III (Renal system)/test Exam C OLLOQUIUM P2, dr. sc. lan Šućur, dr. sc. Vilma Dembitz, dr. sc. lan Šućur, dr. sc. Vilma Dembitz dr. sc. Vilma Dembitz dr. sc. lan Šućur Darja Flegar, dr. med. Exam C OLLOQUIUM P2 dr. sc. lan Šućur Lectures L9 - INTRODUC ING GSTROINTESTINL PHYSIOLOGY Teaching staff

7 Date Time Group Course hours type Theme Wednesday Friday Monday Wednesday Friday Monday :00-13:15; Nova vijećnica 13:30-15:45; Nova vijećnica Kompjutorska učionica (C) - Šercer 09:30-11:00; (C) - Šercer 11:15-12:45; (C) - Šercer 12:45-15:45; I 16:00-19:00; I 08:15-09:00; Č ačković 08:15-09:00; Nova vijećnica 09:30-11:00; Č ačković S21 - GI I - Principles of GI function, motility, nervous control, circulation S21 - GI I Principles of GI function, motility, nervous control, circulation S22 - GI II - Secretory functions, digestion and absorption S22 - GI II - Secretory functions, digestion and absorption S23 - GI III - Metab. of carbohydrates, lipids and proteins S23 - GI III - Metab. of carbohydrates, lipids and proteins S24 - TERMOREGULTION, METOLISM S24 - TERMOREGULTION, METOLISM S25 - INTEGRTION IV S25 - INTEGRTION IV Practicum P8 - SL METOLISM Practicum P8 - SL METOLISM S25 - INTEGRTION IV (GI PHYSIOLOGY)/TEST S25 - INTEGRTION IV (GI PHYSIOLOGY)/TEST, dr. sc. Hrvoje Lalić, dr. sc. lan Šućur, dr. sc. Vilma Dembitz, dr. sc. lan Šućur Darja Flegar, dr. med. Lectures L10 - INTRODUCING ENDOCRINE SYSTEM S26 - PITUITRY GLND leksandra S26 - PITUITRY GLND leksandra S27 - THYROID GLND S27 - THYROID GLND S31 - REPRODUC TIVE PHYSIOLOGY S31 - REPRODUC TIVE PHYSIOLOGY Teaching staff leksandra leksandra

8 Date Time Group Course hours type Theme Wednesday 12:00-14:15; S29 - C LC IUM, PHOSPHTE LNC E 14:30-16:45; S29 - C LC IUM, PHOSPHTE LNC E 17:00-20:00; I Practicum P10 - THORN Friday Monday Wednesday :00-14:15; 14:30-16:45; 17:00-20:00; 09:00-12:00; I 13:00-16:00; I 13:15-15:30; 16:00-19:00; I 13:15-15:30; 16:00-19:00; I 08:00-09:30; 09:45-11:15; 12:00-15:00; 15:15-18:15; 08:00-09:30; 09:45-11:15; 11:30-13:00; S28 - DRENL GLND S28 - DRENL GLND Practicum P10 - THORN Practicum Practicum Practicum P11 - OGTT Practicum P11 - OGTT P9 - THYROID HORMONE & O2 C ONSUMPTION IN RTS P9 - THYROID HORMONE & O2 C ONSUMPTION IN RTS S30 - LOOD GLUCOSE, INSULIN, GLUC GON S30 - LOOD GLUCOSE, INSULIN, GLUC GON Lectures L11 - PREGNNC Y ND LC TTION Lectures L12 - FETL ND NEWORN PHYSIOLOGY Practicum P12 - ÅSTRND Practicum P12 - ÅSTRND S32 - INTEGRTION V Lectures L13 - SPORTS PHYSIOLOGY S32 - INTEGRTION V Teaching staff dr. sc. Vilma Dembitz, dr. sc. lan Šućur, dr. sc. Hrvoje Lalić leksandra leksandra, dr. sc. lan Šućur, dr. sc. Hrvoje Lalić dr. sc. lan Šućur, dr. sc. Hrvoje Lalić, dr. sc. Vilma Dembitz dr. sc. Hrvoje Lalić, dr. sc. Vilma Dembitz, doc. dr. sc. Vladiana C rljen dr. sc. Hrvoje Lalić, dr. sc. Vilma Dembitz, dr. sc. lan Šućur dr. sc. Hrvoje Lalić, dr. sc. Vilma Dembitz, dr. sc. lan Šućur Kelava Kelava, dr. sc. Vilma Dembitz, dr. sc. Hrvoje Lalić Kelava, dr. sc. lan Šućur, dr. sc. Hrvoje Lalić leksandra leksandra

9 Date Time Group Course hours type Theme Teaching staff Friday Friday Monday :00-10:45; Č ačković 10:00-10:45; Nova vijećnica 10:00-11:00; iološka 10:00-11:00; Nova vijećnica 13:00-16:45; Č ačković 08:30-13:45; 08:30-13:45; 08:30-13:45; 08:30-13:45; 08:30-13:45; 08:30-13:45; 08:30-13:45; 08:30-13:45; SVI SVI Exam C OLLOQUIUM P3 Exam C OLLOQUIUM P3 S32 - INTEGR V (End.S.;Preg.Lac.; Fet.New; Spor.) /TEST S32 - INTEGR V (End.S.;Preg.Lac.; Fet.New; Spor.) /TEST Exam C OLLOQUIUM P1 OR P2 Exam Provjera znanja Exam Provjera znanja Exam Provjera znanja Exam Provjera znanja Exam Provjera znanja Exam Provjera znanja leksandra Nikola Habek, dr. med. Nikola Habek, dr. med. Kelava, dr. sc. lan Šućur Darja Flegar, dr. med., doc. dr. sc. Vladiana C rljen Kelava, dr. sc. lan Šućur Darja Flegar, dr. med., doc. dr. sc. Vladiana C rljen Kelava Nikola Habek, dr. med. Exam Provjera znanja dr. sc. lan Šućur Exam Provjera znanja dr. sc. Hrvoje Lalić LIST OF LECTURERS ND TECHING STFF Prof. Hrvoje, Head of the Departement Prof. Dora ssoc. Prof. ssoc. Prof. leksandra Sinđić ssist. Prof. Vladiana ssist. Prof. Vesna Lukinović Škudar ssist. Prof. Tomislav Kelava ssist Prof Marija Renić Senior Instructor Hrvoje Lalić, MD, PhD Senior Instructor lan Šućur, MD; PhD Senior Instructor Vilma Dembitz, MD, PhD

10 Instructor Darja Flegar, MD Instructor Nikola Habek, MD LIST OF EXMINERS Prof. Hrvoje Prof. Dora ssoc. Prof. ssoc. Prof. leksandra Sinđić ssist. Prof. Vladiana ssist. Prof. Vesna Lukinović Škudar ssist. Prof. Tomislav Kelava CONSULTTIONS Prof. Hrvoje Consultations: TUESDY 16,00-18,00 ssist. Prof. Vladiana Consultaions: WEDNESDY 13,00-15,00 Prof. Dora Consultations: MONDY 14,00-16,00 ssoc. Prof. Konzultacije: prema dogovoru ssoc. Prof. leksandra Sinđić Consultations: MONDY 15,00-17,00 ssis. Prof. Vesna Consultations: FRIDY 12,00-14,00

11 ssis. Prof. Marija Renić Consultations: MONDY 14,00-16,00 doc. dr. Tomislav Kelava Consultations: THURSDY 12,00-14,00 Senior Instructor Hrvoje Lalić, MD, PhD Consultations: TUESDY 14,00-16,00 Senior Instructor lan Šućur, MD, PhD Consultations: THURSDY 13,00-15,00 Senior Instructor Vilma Dembitz, MD, PhD Consultations: WEDNESDY 14,00-16,00 Instructor Darja Flegar, MD Consultations: WEDNESDY 14,00-16,00 Instructor Nikola Habek, MD Consultations: THURSDY 12,00-14,00 Lectures: 1. Introducing membrane transport (2) 2. Introducing cardiovascular system (1) 3. Introducing circulation; Laplace law (2) 4. utonomic nervous system (1)

12 5. lood clotting (2) 6. Introducing respiratory system (2) 7. Flying and diving (2) 8. Introducing renal system (2) 9. Introducing gastrointestinal physiology (2) 10. Introducing endocrine system (2) 11. Pregnancy and lactation (2) 12. Fetal and Newborn Physiology (2) 13. Sports Physiology (2) topics: S SEMINR TITLE Theme Chapter 1 CELL (3) Cell & membrane potential 4, 5 2 MUSCLE (3) Structure of skeletal, smooth muscle, mechanism of contraction, control of skeletal muscle contraction excitation contraction coupling, neuromuscular transmission, mechanics and energetic of skeletal muscle contraction, smooth muscle 6,7,8 3 HERT I (3) Cardiac muscle characteristic; Electrophysiology of heart 9 (p ), 10 4 HERT II (3) Cardiac function, cardiac cycle, cardiac defects (heart sounds) 9, 23 (p ) 5 ECG, VECTOR NLYSIS Electrocardiogram (ECG); (3) Vector analysis 11, 12 6 CIRCULTION I (3) rterial pressure and circulation 14, 15 Fluid dynamics, the microcirculation and lymphatic; 7 MICROCIRCULTION (3) Local control of blood flow 16, 17 8 CIRCULTION II (3) Regulation of arterial pressure, 18, 19 9 CIRCULTION III (3) Cardiac output and venous return; Coronary circulation, skeletal muscle circulation 20, 21 (p )

13 10 INTEGRTION I (3) Case: Hypovolemic shock* Case: cute myocardial infarction* TEST RESPIRTION I (3) Pulmonary ventilation; Pulmonary circulation 38, RESPIRTION II (3) Principles of gas exchange; Oxygen and carbon dioxide transport 40, RESPIRTION III (3) Regulation of respiration INTEGRTION II (3) Case: Obstructive lung disease* TEST 31, 38-42; 43 (p ) 15 ODY FLUIDS ND ELECTROLYTES (3) Edema, hyperhidration, dehydration KIDNEY I (3) Structure of kidney and nephrons, glomerular filtration rate; Renal hemodynamics; Renal clearance 26, (p ) 17 KIDNEY II (3) Transport and processing properties of tubular segments; Regulation of potassium, calcium, phosphate and magnesium 28 (p ), 30 (p ) 18 KIDNEY III (3) Regulation of extracellular fluid volume and osmolarity; Urine concentration and dilution; Micturation; Dialysis 29, 30 (p ), 32 (p , p ) 19 CID SE LNCE (3) cid-ase alance 31 Case: cute glomerulonephritis* 20 INTEGRTION III (3) Case: Secondary arterial hypertension* TEST (32) 21 GSTROINTESTINL SYSTEM I (3) Principles of gastrointestinal function: motility, nervous control, blood circulation; Reflexes, Propulsion and mixing of food 63, GSTROINTESTINL SYSTEM II (3) Secretory functions; Digestion and absorption 65, 66

14 23 GSTROINTESTINL SYSTEM III (3) Metabolism of carbohydrates, lipids, and proteins; ilirubin, bile secretion, carbohydrate, nitrogen, lipid and protein metabolism, conjugation and detoxification; Liver 68, 69, 70, TERMOREGULTION ND METOLISM (3) Dietary balances, regulation of feeding; Metabolic rate; Regulation of body temperature 72, 73, INTEGRTION IV (3) Case: Gastrointestinal system* TEST PITUITRY GLND HORMONES (3) Pituitary hormones THYROID GLND HORMONES (3) Thyroid metabolic hormones DRENOCORTICL HORMONES (3) Mineralocorticoids; Glucocorticoids CLCIUM ND PHOSPHTE LNCE (3) Calcium and phosphate metabolism, vitamin D; PTH and Calcitonin REGULTION OF LOOD GLUCOSE CONCENTRTION (3) Insulin, glucagon, liver, skeletal muscle, cortisol, catecholamine, growth hormone, tyrosine REPRODUCTIVE PHYSIOLOGY (3) Male hormone; Female hormone 81, INTEGRTION V (3) Cardiovascular changes, respiratory changes, kidney response, insulin sensitivity and glucose uptake, health benefits, endocrine changes PRCTICL WORK: Students will be introduced through practical work to diagnostic tests that are routinely used in medicine. Due to ethical reasons some of the exercises will be performed on animals (laboratory rats). In that way we will also show our students how to work with laboratory animals, what can be helpful in their future scientific work. lso some of the exercises are designed as scientific experiments. In line with that, some practicals are designed as scintific experiments. When it is possible, the animal experiments are replaced with computer simulation.

15 Practical work topics: 1. MEMRNE POTENTIL - PRT 1 and 2 (6) - LMS, Gu. 4, 5 2. ECG. MESURING RTERIL LOOD PRESSURE. (4) - LMS, Gu 11, 12, 14 (p ), 15 ( ) 3. ERYTROCYTE COUNT. HEMOGLOIN. HEMTOCRIT. SEDIMENTTION RTE. (5) - LMS, Gu LOOD CLOTTING TESTS (3) - LMS, Gu PLETISMOGRPHY, POLIGRPHY (4) - LMS 6. SPIROMETRY (4) - LMS, Gu 38 (p ); 43 (p ) 7. PROLEM SOLVING (model KIDNEY); ERYTROCYTE - MEMRNE RESISTNCY (4) - LMS, Gu 26, 27, 28, MESURING THE RTE OF SL METOLISM IN HUMN. (4) - LMS, Gu 73 (p ) 9. EFFECT OF THYROID HORMONE ON OXYGEN CONSUMPTION IN RT (4) - LMS, Gu 77 (p ) 10. THORN TEST. INDUCING THE HYPOCLCIEMIC TETNY IN RT. (4) - LMS, Gu 80 (p ) 11. GLUCOSE TOLERNS TEST. INSULIN INDUCED HYPOGLYCEMI IN RT (4) - LMS, Gu 79 (p ) 12. CHNGES IN CRDIOVSCULR SYSTEM INDUCED Y MUSCLE WORK. STRND. EMG (4)- LMS

16 Students should come prepared to practicals. Description of each practical is given on the LMS. lso, students should read textbook (Guyton) to get ready for practical. Next to each practical listed above is given chapter(s) from textbook that should be prepared in advance. Šalata 3 Departement of Physiology Lecture room (PL) and practical room (PP, PP2) Lectures will take place in hall: Physiology lecture room (PL) or available lecture room (L) in main building according to schedule s will take place in hall: Physiology lecture room (PL) or available lecture room (L) in main building according to schedule IV. EXMINTIONS IV.a. EXM POLICY: Exam questions will include material presented in lecture, assigned chapter readings and case studies distributed during class or posted on the course web site. Questions are multiple choice with only one correct answer. Each question accounts for one point and there are no negative points. Major colloquium quizzes Three major colloquium quizzes will be held during the course. These quizzes are named Ph-1, Ph-2 and Ph-3 colloquium. Each quiz is made up of 60 multiple choice questions equally distributed through textbook obligatory chapters. Ph1 colloquium - includes general physiology, muscle physiology and the cardiovascular system (topics covered in lectures 1-5, seminars 1-10 and practical work 1-5), Ph2 colloquium - includes physiology of kidney and respiratory system (topics covered in lectures 6-8, seminars and practical work 6-7), Ph3 colloquium - includes physiology of digestive system, metabolism and endocrinology (topics covered inlectures 9-13, seminars and practical work 8-12) Students are given 90 minutes to complete each colloquium quiz. The score of each colloquium (P1-P3) contributes 33.3% to the final grade at the end of the course.

17 IMPORTNT! The Physiology department strongly encourages students to take and pass the major colloquium quizzes since it gives the students a great opportunity to carry the passing grades, achieved on each of three colloquium quizzes, from one to another final exam. (e.g. if student passed the Ph1 colloquium quiz he does not need to retake the Ph1 part of the final exam again during current academic year 2017./18) onus points (points earned on the small integration quizzes) During the course students have obligation to take integration tests. There are five integration tests (after each physiology functional unit there is integration test). Passing these tests gives our students opportunity to earn bonus points. The bonus points earned during the course will be added to the total score of each of the corresponding colloquium quizzes (P1- P3). The bonus points will be added only if student earned 55% or more of the total score on the corresponding colloquium quizzes Final exam The Final Exam is composed from two parts: written test and oral exam. To qualify for the oral exam student must pass the written exam. Written test is composed of three parts: P1 + P2 + P3. Exam writers are given 90 minutes to complete each test part with 30 min break between each part. Written part of exam has the elimination threshold. Student need to have average score 55% or more on each part of the written exam for passing level. Oral exam is obligatory for the students who earned 55% and 85% of the total score on the written exam. Students who earned 85% and more of the total score on the written exam are exempt from taking oral exam. The final grade will depend on a grade given at the end of oral exam. IV.b. GRDING CRITERI For passing the colloquiums and exams it is necessary to achieve a positive assessment of written part. Grades will be determined on the basis of an objective standard of absolute difficulty of the test (called MPR) at: 85% of the total score on the test for excellence, 75% of the total score on the test for very good, 65% of the total score on the test for good, 55% of the total score on the test for satisfactory.

18 IV.c. EXM RESULTS: Exam results will be posted on the Department of Physiology LMS page. IV.d. CDEMIC HONESTY ll students are expected to help to maintain an environment of academic honesty. The following behaviors are strictly forbidden during the administration of the exam: talking, cell phone use, and passing of papers or notes. ll backpacks, coats, cell phones, etc. are to be placed in the front of the room. ll students are required to hand-in the packet of exam questions with their name clearly indicated on first page of the exam. It is the responsibility of the student to make sure that the answers he/she wants graded are clearly marked on the scantron sheet with a #2 lead pencil.. Types of examination and examination dates Mandatory written small colloquiums: Integration I ; Integration II ; Integration III ; integration IV ; Integration V Mandatory written big colloquiums: Colloquium P ; Colloquium P ; Colloquium P Eligibility Criteria The criteria for application to take the final exam are as follows: For the final exam can apply: students who attended classes (seminars and practical) regularly, students who passed colloquium (for seminars and practical that were unattended) students who have signature in index for Physiology course Colloquium for seminars and practical that were unattended is held by teachers who lead the seminar or practical that student did not attend. The policy for colloquium: to be able to take colloquium student need to have the colloquium application sheet (student can get it in the room beside the practicum room) the teacher s signature in the colloquium application sheet is necessary to confirm that student successfully passed the colloquium.

19 To get index signed student must regularly attend classes and pass all colloquiums for classes unattended. Examination dates Regular terms Date Winter (Final exam for ac. year 2016./17. generation) Summer utumn V./I. LIST OF LECTURERS ND TECHING STFF leksandra Kelava 8. dr. sc. Hrvoje Lalić 9. dr. sc. lan Šućur 10. dr. sc. Vilma Dembitz 11. Darja Flegar, dr. med. 12. Nikola Habek, dr. med. 13. doc. dr. sc. Marija Renić V./II EXTERNL SSOCITES:

20 V./III UNTENURED LECTURERS: VI. LITERTURE. Obligatory Guyton C, Hall JE: Textbook Of Medical Physiology, 13th Edition, dditional (in alphabetical order): W. oron and E. oulpaep. Medical Physiology 3rd Edition, ISN: R.M. erne and M.N. Levy. Physiology 6th Edition, Mosby, D.R. ell. Core Concepts in Physiology. Lippincott-Raven, ISN: Linda S. Costanzo Physiology: oard Review Series, Lippincott, Williams & Wilkins; 2nd edition Chapters from Guyton Textbook for exam: Ph-1 includes chapters 4, 5,6, 7, 8, 9,10,11, 12, 14, 15, 16, 17, 18, 19, 20, 21, 23 (pages untill "Valvular Leasions"), 33, 34, 37, 61 Ph-2 includes chapters; 25, 26, 27, 28, 29, 30, 31, 38, 39, 40, 41, 42, 43 (pages untill "Pathophysiology of Specific Pulmonary bnormalities"), 44, 45 Ph-3 includes chapters: 63, 64, 65, 66, 68,69, 70, 71,72, 73, 74,75, 76, 77, 78, 79, 80, 81, 82, 83, 84,85 Reading ssignments: Students are expected to read the assigned chapters prior to coming to class. The exams will draw heavily upon material discussed during lectures; however, students are still expected to master the material in the assigned chapters NOTE: -Learning management System (-LMS) -LMS is a platform designed to support teaching and learning at School of Medicine University of Zagreb. -LMS is used for the administration and delivery of the course materials, communication between students and teachers, students self assessments

21 Physiology course materials will be available on the Physiology LMS page Intellectual Property We ask you to respect the intellectual property of the authors of the course content. Course materials posted on the physiology LMS page is copyrighted, by virtue of its publication on the internet, under the Millennium ct. s such, students are reminded that it is illegal to copy or distribute any of these materials unless it is for personal use, or you have obtained the consent of the authors of the copyrighted materials.