Application of Breakthrough

Transcription

1 Application of Breakthrough Sensor Technology to Medical Diagnostic Equipment 21 August 2011 Levon P. Thorose PSI CEO Precision Instrumentation Inc. (PSI)

2 Content Breakthrough Sensor Technology Differentiating Advantages Technology Readiness Applications in Medical Diagnostics The New Spectrum of visibility Entirely New Class of Medical Diagnostic Equipment (MDE) is borne The Next Step Summary Conclusion

3 Penetration depth [ m] Penetration depth [ m] Frequency shift, F [khz] Power [W] Frequency shift, ( F) [khz] History of the Technology Super-Conductivity R&D Normal-to-Superconductive TEMPERATURE TRANSITION CURVES Y 1 Ba 2 Cu 3 O 7- Film 8mm T abs =84.9K Power [W] T 0 =85.6K Kyushu Univ., JAPAN New Marketing And Systems Applications GSC PSI T C =89.0K Temperature [K] Frequency [Hz] "Paramagnetic" Effect: (real shape of Normal-to-Superconductive transition curve) New Physical Effects & Principles T 0 = 85.6K A PE 8mm Temperature [K] Temperature [K] YBaCuO Film T C = 89.0K Prototype Seismic Sensor Birth of New Class of Products Early Warning Systems (EWS) Border / Port Security Systems Military and Civilian Applications Medical Diagnostics Instrum.(MDI) Probes, Monitoring, Intelligence Portable MRI Many New MDI New Industrial Products (NIP)

4 Introduction to SFCO Technology: Reasons for High Resolution Sample World Standard High-T c Superconductors (SC) m; l 0.15 m PSI Offer: 10 4 x enhanced Huge change of Flat-coil Inductance l Cylindrical Coil Low-T c SC 2 5 m; 4 l m 4

5 Sensitivity Comparing World Class Seismic Sensors New Sensor Freq~1Hz New Sensor Russian: SM-3 Simultaneous sensors tests responding to the same excitation Russian: SM-3 Swiss: STS-2 USA: KS F r e q u e n c y Disruptive Competitive Advantage times more sensitive than the American KS-54000, 30 times more sensitive than Swiss STS-2, 100 times more sensitive than the Russian SM-3 Near 0 Hz

6 S e n s I t I v I t y Resonant frequency shift δ F [MHz] Sensitivity Relationship Position vs Frequency Shift d 0 G~0.7A /Hz 1 Angstrom/Hz G W ~0.9A /Hz (optimal work point) 2 Angstrom/Hz G~1.7A /Hz δ F=δ1 Angstrom F 0 +Aexp [- (d-d 0 )/t ] δ F 0 =0.167 resolution MHz measured d 0 =200 μat m liquid-helium A=6.8 temperatures MHz t=500 (4K); Fitting μ m G -δ d/δ F 1 G~4.5A /Hz G~73.6A /Hz 5 Angstrom/Hz 0 coil plane distance d [ m] Distance d+do 0 [μ m] Position ( microns) 6

7 Discriminating Advantages Mission Critical to Medical Diagnostics 1. Absolute Position Sensing Absolute Position shift resolution: ( d 10 Å at room temp) Most discriminating advantage One Nanometer resolution 2. Super wide frequency bandwidth Starting from zero to 100 KHz Huge discriminating advantage 3. Relative resolution d /d 10-6, Superior to Superconductive Quantum Interference Device (SQUID) 4. Wide dynamic range 1 Nanometer to 1 milliliter, also Superior to SQUID 5. Sensitivity (10-10,000) times better than the best in same class 6. High magnetic fields Superior to SQUID 7. Power Absorption P 10 9 to-10 W Superior to SQUID Passive, Remote, Sensors For Medical Diagnostics

8 Global Security Challenge Technology Competitions In 2008 PSI Achieved the Top Six Finalist World Finalists: Semi-finalists: Top 5 Top 5 Top 5 * Washington DC London * * Singapore 8

9 Best in Class for Reference 100 To Compare with Best in Class Frequency Response SM 24 ST world class Geo sensor - Reference Sensitivity / V/m/s Frequency (Hz)

10 Discriminating Advantage 100 Comparisons in Frequency Response Sensitivity / V/m/s Extraordinary Advantage Over Other Sensors In Low frequencies Sensitivity / V/m/s 10 1 SM 24 ST world class Geo sensor Very Slow Movements Frequency (Hz)

11 Measures Ground Movements Caused by the Moon or the Sun on Earth, When Passing Over Measuring The movement of Moon Measuring Earth Quake in Manila Measuring Movements Caused by Moon on Earth Lab Data Friday Evening March

12 Additional Spectrum Sheds New Light for New Class of Medical Diagnostic Equipment 100 Comparisons in Frequency Response Sensitivity / V/m/s Sensing Vital Body Functions With High Resolution Sensitivity / V/m/s 10 1 SM 24 ST world class Geo sensor Frequency (Hz) Monitoring vital body functions in ICU, or during surgical operations 0.8 to 3 Hz, Monitoring Heart Regulations 0.13 to 0.53 Hz, Monitoring Respiratory System Regulations to 0.05 Hz Many vital body functions can be monitored

13 Limited laboratory tests shows sensors flexibility and potential applicability Laboratory Tests Performed The quick tests provided adequate data to show that testing of body internal activities can be measured/recorded as the SFCO sensor is placed on various locations on the body. Nano meter resolution Low frequency Sensitivity Ultra wide frequency provides for automatic recognition Force Mode Relax mode Figure 2. Remote measurements of the isotonic activities as a result of finger flexure Figure 1. shows the isometric activity of musculus biceps brachii. Kludge sensor placed on the skin

14 The SFCO sensor has clearly recorded two super-imposed separate organ activities; the vocal cords pronouncing the English alphabet, and the heart related motions.

15 Lung Monitoring and Diagnostics Made Possible with More Resolution Senses and records the air vibrations taking place in the air paths all the way to and including vibrations in alveoli Emphysema Asthma, Voice vocalization disturbances Given sensor s 1 nm resolution, the significant information is processed via pattern recognition and spectra Fourier transformation conversion of native data reveals about health of the organ/body system Printout the lung status in minutes

16 General Diagnostics Made Easier Sensors can record the spontaneous or evoked vibrations and acoustic phenomena from heart, lung, vessels, bones, and other vital organs Sensors can monitor intracranial pressure (ICP) Signal information is processed via pattern recognition of native data, and spectra after Fourier transformation conversion reveals significant information about health SFCO Sensor Resonator of evoked, or spontaneous acoustic phenomena from heart, lungs, vessels, bones, etc.

17 Internal Pressure Monitoring and Diagnostics The New Technology sensors: Sense and record Intra abdominal Pressure (IAP), Direct arterial and venous pressures: Monitor Esophagus swallowing functions/activities. Monitor Intestinal slow motions activities. Monitor Urinal tract and bladder slow motions activities.

18 Potential for Portable MRI Development Magnetic imaging by 100 fold sensitivity improvement Simplification of the magnetic scanning mechanism Improvement to MRI resolution PSI Lab Test Data Differentiating SFCO Technology Advantages that can contribute to MRI technology Differentiating Parameter Absorption Scanning Mechanism S t a n d a r d Te c h n o l o g y 10-6 to 10-7 W Standard Resolution Complex magnetic Gradient Shaping S F C O Te c h n o l o g y 10-9 to 10 W X10 Improved Resolution Eliminate Gradient Coil, much simpler mechanism Size and Cost Industry Standards Reduced in Size And Less in Costs

19 Potential for Portable MRI Development Magnetic imaging by 100 fold sensitivity improvement Simplification of the magnetic scanning mechanism Improvement to MRI resolution T e c h - n o l o g y Differentiating SFCO Technology Advantages S pecification Standard conventional MRI Absorption resolution [ Watt ] 10 6 to 10 7 Watt Scanning mechanism ( s l i c i n g a n d d i c i n g ) 2D skin shaped tumor study 3 gradient magnets X, Y and Z, axis 3D spatial, volume tumor study 3 gradient magnets X, Y Z axis SFCO technology based MRI much better 10 9 to10 10 Watt One SFCO scans 2D tumor by its needle-type testing RF-field (X Y) plane (flat scan) Three SFCO scan 3D tumor by their needle-type testing RF-fields (volume scan)

20 Plenty of Opportunities for New Medical Instruments The next steps Study body functions in the new spectrum, Classify the measurements with relations to specific health issues Design instruments for monitoring and diagnostic purposes Sensor sizes starting from 2mm to 40 cm in Diameter Sensor sensitivity can be tuned to specific frequency of vital organ activities Sensors are producible and can be custom designed Leave it to Human Ingenuity to determine what kind of medical need can be satisfied with these inherent sensor advantages. Contact PSI when you are ready. addresses: Phone numbers:

21 Summary and Conclusion Introduced to Inherent Advantages of SFCO sensors Breakthrough in sensor performance specification Discriminating advantages Ultra wide dynamic range New Spectrum Ultra High Sensitivity Absorption Power Frequency Response Comparisons Frequency (Hz) Ideal for new medical monitoring and diagnosis in the new spectrum Examples of New Medical Monitoring and Diagnostic Equipment Lung and respiratory system diagnostics prototype level Potential for Portable MRI development Many Other MDI opportunities No limit to human ingenuity to satisfy the need for New class of MDI Sensitivity / V/m/s Application of This Extraordinary Advantage To Medical Diagnostic Field

22 Questions?