Welcome and Introductions

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2 Welcome and Introductions Jeffrey I. Mechanick, MD, FACP, FACE, FACN, ECNU AACE President Clinical Professor of Medicine Director, Metabolic Support Division of Endocrinology, Diabetes, and Bone Disease Icahn School of Medicine at Mount Sinai

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4 Conference Mission To build an evidence base for comprehensive action to combat obesity in the United States Context Premise Structure Deliverable Future

5 Context Obesity as a disease U.S. Obesity Epidemic Definitions Therapeutic options Complexity Multiple drivers Transcultural differences Inadequate current management strategy Individual Population Need a new management paradigm

6 Premise New strategic paradigm Composite model of obesity Biomedical model Public health Preventive care Cost-effective management Process Build evidence (information) base Translate into actionable recommendations Implementation logistics

7 SUNDAY, MARCH :00 AM - 8:00 AM 8:00 AM - 8:10 AM NETWORKING Continental Breakfast Welcome and Introductions Dr. Jeffrey I. Mechanick, AACE President and Co-Chair 8:10 AM - 8:20 AM AACE Perspective - Obesity as a Disease Dr. W. Timothy Garvey, Chair GENERAL SESSION KEYNOTE SPEAKERS MODERATOR: DR. W. TIMOTHY GARVEY 8:20 AM - 9:05 AM Dr. John Foreyt, Director, Behavioral Medicine Research Center at Baylor College of Medicine 9:05 AM - 9:50 AM Making the Healthy Choice the Easy Choice: Working with Mr. Lawrence Soler, CEO of the Industry to Reduce Childhood Obesity Partnership for a Healthier America 9:50 AM - 10: 00 AM Break 10:00 AM -10:45 AM Senator Tom Harkin, (D-IA) INTRODUCTIONS Context Perspective Introduce pillars KEYNOTES LECTURES Detailed information Expert opinions Structure (Tentative) 10:45 AM - 11:30 AM 11:30 PM - 11:45 AM Summary 11:45 AM - 1 PM Lunch PILLAR BREAKOUT SESSIONS 1:00 PM - 5 PM Biomedical Government/Regulatory Health Industry/Economics Society/Education/Research 5:30 PM - 6:30 PM 6:30 PM Reception Dinner on your own 7:00 AM - 8:00 PM 8:00 AM - 8:05 AM 8:05 AM - 8:35 AM Continental Breakfast Welcome Question 1: What is Obesity? 8:35 AM - 8:45 AM 8:45 AM - 9:15 AM Q&A Question 2: What Options are Available for Obesity Management? 9:15 AM - 9:25 AM 9:25 AM - 9:40 AM 9:40 AM - 10:10 AM Q&A Break Question 3: What is the Optimal Use of Therapeutic Modalities? 10:10 AM - 10:20 AM 10:20 AM - 10:50 AM Q&A Question 4: Can the Optimal Framework be Cost-Effective? Dr. Patrice Harris, American Medical Association Board of Trustees Dr. W. Timothy Garvey, Chair Moderators: Dr. W. Timothy Garvey, Chair Dr. Alan J. Garber, Co-Chair Dr. Jeffrey I. Mechanick, Co-Chair Dr. Janet B. McGill Dr. George Grunberger MONDAY, MARCH 24, 2014 Dr. Timothy Garvey, Chair Dr. Alan J. Garber, Co-Chair N WITHIN PILLAR BREAKOUT SESSIONS 1. Biomedical N 2. Government &Regulatory 3. Industry& Economics 4. Organizations, Education & Research Critical process Formalize pillar responses to 5 questions 1. What is obesity 2. Available options 3. Optimal tx 4. Cost-effectiveness 5. Knowledge gaps Dr. W. Timothy Garvey, Chair Dr. W. Timothy Garvey, Chair AMONG PILLAR BREAKOUT SESSIONS Critical process Interactive discussion by question Evidence base created/vetted Dr. Jeffrey I. Mechanick, Co-Chair Q&A 10:50 AM - 11:00 AM N WRITING COMMITTEE Conference transcripts AACE/ACE primary writers Medical writer Executive Summary Structured by questions MEDIA EVENT Present executive summary to media EMERGENT PROCESS

8 Deliverable Structured evidence base Written document with executive summary Introduction Question-oriented evidence base and conclusions Future activities Media event Complete full paper by April 14 Submit for publication in Endocrine Practice

9 Conference Participants Conference Task Force Pillars (to be introduced during program) Writing Committee Staff Sponsors

10 Conference Task Force Dr. W. Timothy Garvey, Chair Dr. Alan J. Garber, Co-Chair Dr. Jeffrey I. Mechanick, Co-Chair Dr. Daniel Einhorn Dr. George Grunberger Dr. Yehuda Handelsman Dr. Jonathan D. Leffert Dr. Janet B. McGill

11 Writing Committee Dr. W. Timothy Garvey, Chair Dr. Alan J. Garber, Co-Chair Dr. Jeffrey I. Mechanick, Co-Chair Dr. George A. Bray Dr. Samuel Dagogo-Jack Dr. Daniel Einhorn Dr. George Grunberger Dr. Yehuda Handelsman Dr. Charles H. Hennekens Dr. Daniel L. Hurley Dr. Janet B. McGill Dr. Pasquale J. Palumbo Dr. Steven R. Smith Dr. Guillermo E. Umpierrez

12 AACE Staff Don Jones, CEO Dan Kelsey, Deputy CEO Glenn Sebold, Director of Public & Media Relations Amy Johnson, Public & Media Relations Project Coordinator Sissy Horn, Special Project Coordinator

13 Corporate Support Platinum Gold Silver Bronze Takeda Covidien Ethicon

14 Professor of Medicine First Speaker: W. Timothy Garvey, MD Chair of Department of Nutrition Sciences University of Alabama at Birmingham International recognition for research in diabetes, nutrition, and obesity