Jay Ash Secretary of Housing & Economic Development, Commonwealth of Massachusetts

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1 8:00-9:00 am Breakfast and Registration Foyer 9:00-9:30 am Welcome Remarks, Overview of Meeting & MassBio Board Elections Robert K. Coughlin President & Chief Executive Officer, MassBio Glenn Batchelder Founder & Board Member, Civitas Therapeutics Chairman, MassBio Board of Directors Jay Ash Secretary of Housing & Economic Development, Commonwealth of Massachusetts 9:30-10:15 am Opening Keynote, introduced by David Lucchino, MassBio Board of Directors Kathy Guisti Founder & Executive Chairman, Multiple Myeloma Research Foundation

2 10:15 10:30 am Coffee Break 10:30-11:30 am Breakout Sessions It s Not Your Grandfather s Manufacturing David Smith Head, Cell Therapy Manufacturing, Lonza Bayan Takizawa Co-Founder & Chief Business Officer, CONTINUUS Pharma Gary Welch Plant Manager, AbbVie BioResearch Center Geoffrey Hodge Bioprocess Technology Leader, GE Healthcare Life Sciences From Bioterrorism to Superorganisms: Perils, Pitfalls & Promise Chris Garabedian President & Chief Executive Officer, Sarepta Therapeutics Tim Hunt Senior Vice President, Public Affairs, Cubist Pharmaceuticals David Lubner Chief Financial Officer, Tetraphase Pharmaceuticals Kendall Hoyt Assistant Professor, Medicine, The Geisel School of Medicine at Dartmouth Author, Long Shot: Vaccines for National Defense Steven C. Gilman MassBio Board of Directors 11:45 am -1:30 pm The MassBio Annual Awards Luncheon 2014 Joshua Boger Innovative School of the Year Award Presented to Barnstable High School, by Genzyme Corporation 2014 Henri A. Termeer Innovative Leadership Award Presented to Mark Levin, Co-Founder, Third Rock Ventures 2015 MassBio Leading Impact Award Presented to Michael F. Collins, MD, FACP, Chancellor, University of Massachusetts Medical School

3 1:30 2:20 pm Precision Medicine: What s the Opportunity? David Altshuler Executive Vice President, Global Research & Chief Scientific Officer, Vertex Pharmaceuticals Walter Carney Chief Scientific Officer & General Manager, Nuclea Diagnostics Susan Hager Vice President, Communications & Government Affairs, Foundation Medicine Jeff Elton Managing Director, Life Sciences, Accenture 2:25 3:15 pm Breakout Sessions II Externalizing Pharma R&D Ashish Dugar Head, External Development Group, Roche Thomas Luby Senior Director, New Ventures, Johnson & Johnson Innovation John Orloff Global Head, Research & Development, Baxter BioSciences Lisa Warren Managing Partner, Morse, Barnes-Brown & Pendleton, PC Tacye Connolly Owner, Regulatory Resources Group, a VCLS Company Trends in Healthcare Technology Zen Chu Senior Lecturer, Healthcare Innovation, MIT Sloan School of Management Peter Covitz Senior Director, Information Strategy & Analytics, Pfizer David Dore Vice President & Principal Epidemiologist, Optum Adjunct Professor, Brown University School of Public Health

4 3:15 3:30 pm Afternoon Break 3:30 4:20 pm Breakout Sessions III Technology Transfer: Status Quo, Evolution, or Revolution? Julia Gershkovich Head, US R&D Alliance Management, Sanofi Erik Halvorson Senior Director, Technology Transfer & Industry Collaborations, Tufts University Monique Yoakim-Turk Associate Director, Technology & Innovation Development Office, Boston Children s Hospital Fred Ledley Professor & Director, Center for Integration of Science and Industry, Bentley University Immunotherapy: Oncology & Beyond Mani Mohindru Vice President, Corporate Strategy & Investor Relations, Curis, Inc. Anna Protopapas President & Chief Executive Officer, Mersana Therapeutics Leslie Williams President & Chief Executive Officer, ImmusanT, Inc. Philip G. Vanek General Manager, Cell Therapy Technologies, GE Healthcare Life Sciences 4:20 6:30 pm Networking Reception Foyer

5 Friday, March 27th 8:00-8:40 am Breakfast Foyer 8:40-9:30 am Breakout Sessions IV Innovative Ways to Fund Your Early-Stage Company Navroze Alphonse Managing Member, Crossover Capital Management LLC Ellen Baron Managing Director, Healthios Capital Markets, LLC Walter Capone President & Chief Executive Officer, The Multiple Myeloma Research Foundation Yuval Cohen Chief Executive Officer, Corbus Pharmaceuticals Rick Jones Director, Broadview Ventures William Whelan Co-Chair, Life Sciences Practice, Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, PC Current & Future Impact of Editing, CART & Gene Therapy Nessan Bermingham Chief Executive Officer & Founder, Intellia Therapeutics Kevin Bitterman Partner, Polaris Katrine Bosley Chief Executive Officer, Editas Medicine Nick Leschly chief bluebird, bluebird bio

6 Friday, March 27th 9:40-10:30 am Breakout Sessions V Reimbursement & Market Access: It s a Changing World Steve Hass Vice President, Patient Outcomes & Medical Economics, Genzyme Corporation Meridith Johnson Director, Health Economics & Outcomes Research, GE Healthcare Life Sciences Steve Miller Senior Vice President & Chief Medical Officer, Express Scripts Lowell Schnipper Chief, Division of Hematology & Oncology, Beth Israel Deaconess Medical Center Leora Schiff Principal, Altius Strategy Consulting Neuroscience Therapeutics Development: Challenges, Opportunities & the Road Ahead Richard Mohs Vice President, Neuroscience Clinical Development, Eli Lilly Jonathan Solomon Chief Executive Officer, NeuroPhage Pharmaceuticals Rudolph Tanzi Vice-Chair, Neurology & Director, Genetics & Aging Research Unit, Harvard Medical School Rajesh Ranganathan Director, Office of Translational Research, National Institute of Neurological Disorders & Stroke, National Institutes of Health 10:30 11:00 am Coffee Break

7 Friday, March 27th 11:00 am - 12 pm Defining Value 12:00-12:45 pm Buffet Lunch Speakers: Sarah Emond Chief Operating Officer, Institute for Clinical and Economic Review Christopher Hansen President, American Cancer Society Cancer Action Network, Inc. William Sibold Senior Vice President, Head of Multiple Sclerosis, Genzyme Corporation 12:45 1:30 pm Keynote: Andrew Lo Charles E. and Susan T. Harris Professor Director, MIT Laboratory for Financial Engineering 1:30 2:00 pm Dessert Buffet & Networking Reception Foyer

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