Wireless Implantable Micro Sensors and Systems for Ambulatory Monitoring and Control of Therapeutic Products

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1 Wireless Implantable Micro Sensors and Systems for Ambulatory Monitoring and Control of Therapeutic Products Matthias Wenzel Campus Micro Technologies GmbH Dr. Diana Hodgins European Technology for Business Ltd IST International Workshop on Wearable and Implantable Body Sensor Networks BSN2005, London CMT 1

2 IP Healthy Aims under EC 6 FP Case Study: Implantable Pressure Sensor System Summary Conclusion & Outlook BSN2005, London CMT 2

3 IP Healthy Aims under EC 6 FP Case Study: Implantable Pressure Sensor System Summary Conclusion & Outlook BSN2005, London CMT 3

4 IP Healthy Aims Integrated Project of the 6th FP, Priority 2 (IST) 1st Call Project Period: 01/12/ /11/2007 Total Budget: 26 Mio. Euro EC-Funding: 15 Mio. Euro 26 contractors Including 8 SMEs Coordinator: ETB Ltd, Realisation of Next Generation Intelligent Medical Implants 15 work packages Cochlear implant Glaucoma sensor Artificial urinary sphincter Sphincter sensor Drop foot implant Intracranial pressure monitor Retina implant Stent-graft monitor BSN2005, London CMT 4

5 Core Technologies Body Area Network (BAN) RF Communication Micro Electrodes Micro Packaging & Assembly Biomaterials & Functional Biointerfaces Implantable Power Sources Sensors & Actuators BSN2005, London CMT 5

6 Medical Products Intracranial Pressure Implant Stent-graft Sensor Cochlear Implant Retina Implant Glaucoma Sensor Upper Limb Movement Control System Artificial Urinary Sphincter Sphincter Sensor BSN2005, London CMT 6

7 IP Healthy Aims under EC 6 FP Case Study: Implantable Pressure Sensor System Summary Conclusion & Outlook BSN2005, London CMT 7

8 Demands on Implantable Pressure Monitors Sensor System for Continuous Monitoring of Intracranial Pressure (ICP) Miniaturized and Flexible for Minimal Invasive Delivery Wireless Communication No Battery or Internal Power Source Highly Biocompatible Electrically and Mechanically Long-term Stable Easy Measurement at Home BSN2005, London CMT 8

9 Telemetric Pressure Sensor System Reader/writer unit Transceiver unit Body Area Network Interface Interface Power RF-transponder Demodulation AC DC Modulation Voltage regulator Interface Energy Data Pressure sensing unit Interface Signal processing Pressure Pressure sensor Reference capacitance Wireless data and power transmission BSN2005, London CMT 9

10 Applications: Intracranial Pressure (1) Monitoring Pressure within the Head under Common Conditions Types of Patient that Potentially Suffer from High Intra Cranial Pressure (ICP): Hydrocephalus Head Injury Cerebral Oedema Benign Intracranial Hypertension BSN2005, London CMT 10

11 Applications: Intracranial Pressure (2) Hydrocephalus Describes State of Excessive Accumulation of CSF within the Fluid System of the Head Causing High Intracranial Pressure Therapy: Draining CSF by Shunts Shunt Failure Approx 40 per 100,000 Individuals have Shunts in Place 125,000 p.a. in USA 3,400 p.a. in There is Currently no Practical Way to Measure Shunt Performance in vivo! BSN2005, London CMT 11

12 Implant Prototype Flip Chip & Surface Mounted Devices on Flexible Circuitry Transmission Frequency MHz Power Consumption V Transmission Distance 2 cm mm 2.20 mm CAPS & Interface IC Telemetry Unit Planar Antenna Coil BSN2005, London CMT 12

13 IP Healthy Aims under EC 6 FP Case Study: Implantable Pressure Sensor System Summary Conclusion & Outlook BSN2005, London CMT 13

14 Summary Conclusion & Outlook New emerging technologies such as micro systems, nanotechnology and biomaterials raising opportunities for developing new medical implants Healthy Aims Consortium will be able to accelerate the introduction of innovative electrically driven implants by high integration of technology experts, manufacturers and clinicians in the development and production chain Implantable telemetric sensor systems will be of significant value for cost-effective continuous monitoring of therapeutic procedures even under everyday life conditions BSN2005, London CMT 14

15 Healthy Aims Consortium Partner Country Partner Country European Technology for Business Ltd Mediplus Ltd Assuta Medical Centers Ltd Israel Mediuniversity of Graz Austria Campus Micro Technologies GmbH Germany microtec Gesellschaft für Mikrotechnologie mbh Germany CEA/Liten France The NEXUS Association France Cochlear Technology Centre Europe Belgium North Bristol NHS Trust Ecole Polytechnique Federale de Lausanne Switzerland Queen Mary and Westfield College, University of London Universitat Rovira I Virgili Spain Saft SA France Finetech Medical Ltd Salisbury District Hospital NHS Trust Hahn-Schickard-Gesellschaft für Angewandte Forschung E.V. Germany TWI Ltd IIP-Technologies GmbH Germany University of Newcastle upon Tyne IMTEK - Institute of Microsystem Technology Germany University of Salford Instytut Technologii Elektronowej Poland VDI/VDE Technologiezentrum Informationstechnik GmbH Germany Interuniversitaire Micro-Elektronica Centrum vzw Belgium Zarlink Semiconductor Ltd BSN2005, London CMT 15

16 Thank You for Your Attention Your Sensor System Integrator Campus Micro Technologies GmbH Universitätsallee 29 D Bremen, Germany Tel: +49 (0) Fax: +49 (0) BSN2005, London CMT 16

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