Discovery. Returns. INVESTOR PROSPECTUS FORUM ACCELERATE AMPLIFY SALES. October 22-23, #BIF19 bio.org/investorforum

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1 INVESTOR FORUM October 22-23, 2019 The Westin St. Francis San Francisco, CA ACCELERATE Discovery. AMPLIFY Returns. #BIF19 bio.org/investorforum SALES PROSPECTUS

2 The BIO Investor Forum is an international biotech investor conference focused on investment trends and opportunities in life sciences, with unbiased emphasis on venture-stage growth and emerging public companies as well as those poised to join the growth watch list in BIO Investor Forum features include: Public and venture-stage company presentations. Expert-led workshops on the latest market and investment opportunities with emphasis on drug and technology development. BIO One-on-One Partnering meetings. Premier opportunity to network with industry executives and investors focused exclusively on life sciences. 1,000+ ATTENDEES 3,000+ PARTNERING MEETINGS SCHEDULED 170 PRESENTING COMPANIES Audience Demographics Like being at JPM without the crowds. TARGET AUDIENCE Private equity and public investors, research analysts, and industry executives focused on investment and business development opportunities in the life sciences. 25% 33% c Biopharma c Investor c Other Companies by Type 42% Musculoskeletal disease Genetic disorder Psychiatric disorder Ocular disease Genitourinary disease Respiratory disease Metabolic disorder Hematological disease Degeneration Endocrine disease 3% 2%2% 3% 3% 4% 4% 4% 4% 5% Dermatological disease 1% Investor (buy-side or sell-side research) 1% Endowment/Foundation Investment Bank Other Royalty/Debt Financing Hedge/Mutual Fund (PM, Buy-Side Research) Family Office Angel Investing 6% 7% 4% 3% 5% 9% All Others 7% Companies by Primary Therapeautic Area 5% 6% Immune disorder Investors by Investor Type 14% 6% Neoplasm 6% 8% 7% 7% Gastrointestinal disease 1% Venture Philanthropy 1% Sell-Side Research 62% Neurological disease Infectious disease Inflammatory disease Cardiovascular disease VC/Corporate VC 2

3 Back to Benefits Breakdown Why Companies Attend Meet one-on-one with new and current investors, analysts, and partnering companies. Get the pulse on the latest life sciences investment trends from sophisticated investment and company executives. Showcase your company story in presentations to qualified investors. Network with peers, investors and potential partners BIO Investor Forum Why Investors Attend Hear from and meet with executives at the top life sciences growth companies. Evaluate fresh investment opportunities including compatible, complementary and competitive companies. Benefit from candid panel discussions with leading clinical experts and investigators with insights on pipeline research and clinical practice. Get a big picture overview of the industry and the issues affecting product innovation, capitalization, and commercialization TOP THERAPEUTIC AREAS FOR SCHEDULED MEETINGS Ocular Disease Diabetes mellitus Prostate tumor Advanced solid tumor Genetic disorder Multiple myeloma Metabolic disorder Hematological disease Immune disorder Breast tumor Autoimmune disease Alzheimers disease Pain Cardiovascular disease Gastrointestinal disease Leukemia Dermatological disease Lymphoma Rheumatoid arthritis Solid tumor Neurological disease Inflammatory disease Infectious disease Neoplasm Cancer The investors were great. I don t know what similar access I ll have to such a collection again. Excellent forum for meeting investors or alliance partners for biotech deals. 3

4 2018 BIO Investor Forum Recap The two-day event hosted over 1,000 Attendees Leaders from six companies at the forefront of microbiome innovation assembled to discuss the latest developments in microbiome-based approaches to improve patient outcomes, including microbiome transplants, bioengineered probiotics, next-generation antibiotics, and microbiome-based drug discovery platforms during Wednesday morning s panel, Using Microbiome-Based Therapies to Improve Patient Outcomes. BIO s CEO Jim Greenwood reflected on the past 25 years of BIO history and highlighted where the industry is headed before Wednesday s Fireside Chat featuring Ed Hurwitz, JD, of MPM Capital and Susanne Mulligan of BMO Capital Markets. During View from the Board: Responding to an Acquisition Offer, panelists were presented with a real-world developing scenario involving an acquisition offer. They responded with practical advice, outlined the sometimes complicated implications of certain situations, and discussed how they would react. Day 1 of the event wrapped up with a networking reception for all attendees on the top floor of the Tower Building at the Westin St. Francis. The panel, Digiceuticals as a New Class of FDA-Approved Therapeutics: Investment & Partnering Opportunities, explored the expansion of this biotech that enables fundamental changes in managing interactions with patients to understand and treat disease. 3,010 BIO One-on-One Partnering TM meetings took place during the 2-day event! Thursday s Plenary Luncheon Fireside Chat featured two industry leaders: Rowan Chapman, PhD., head of Johnson & Johnson Innovation, California, and moderator Deepa Pakianathan, PhD., managing partner of Delphi Ventures. Their diverse experiences provided unique insights into how big and small companies approach partnering and investing and the different points of view that they bring to decision making. #BIF18 featured 177 Presenting Companies spread across 25 different therapeutic focuses. 4

5 2018 BIO Investor Forum Advisory Committee Mahima Agochiya, PhD Business Development & Program Manager, SPARK Translational Research Program, Stanford University Janice Bourque Managing Director, Life Sciences, Hercules Technology Growth Capital Katherine Andersen Senior Market Manager, Head of East Coast & Central, Life Science & Healthcare, Silicon Valley Bank (SVB) Jason Camm Chief Medical Officer, Thiel Capital LLC Vinay Bhaskar, PhD Principal, MPM Capital John Chambers President and Head of Investment Banking, H.C. Wainwright & Co. Alice Chen, PhD Vice President, Accelerator Life Science Partners Jung Choi Chief Business & Strategy Officer, Global Blood Therapeutics Shelley Chu, MD, PhD Partner, Abingworth Douglas Crawford, PhD Partner, BioInnovation Capital Rajeev Dadoo, PhD Partner, S.R. One Limited Jie D Elia, PhD Executive Director, Business Development Transactions, Bristol-Myers Squibb Gini Deshpande, PhD Founder & Chief Executive Officer, NuMedii Tao Huang, PhD, JD Venture Partner, Cenova Capital Charlotte Hubbert, PhD Partner, Gates Foundation Venture Capital Margaret Kim Executive Director, Life Sciences, JPMorgan Chase & Co. Ravi Kiron, PhD Head, BioPharma External Innovation, EMD Serono Jennifer Landress Senior Vice President and Chief Operating Officer, Biocom Sabrina Johnson President and Chief Executive Officer, Daré Bioscience Carolyn Ng, PhD Principal, Vertex Ventures HC Sara Radcliffe President and Chief Executive Officer, California Life Science Association (CLSA) Stephen Ritoch Chairman & Chief Executive Officer, Blaise Group International Mahendra Shah, PhD Managing Director, Vivo Capital Komathi Stem Founder & Chief Executive Officer, monarc Bionetworks Alex de Winter, PhD Managing Director, GE Ventures Samuel Wu, MD, PhD Managing Director, Acuris Partners Asish Xavier, PhD Vice President, Venture Investments, Johnson & Johnson Innovation JJDC, Inc. Matthew Yates, PhD Vice President, Corporate Business Development, Eli Lilly and Company 5

6 Sponsorship Opportunities & Benefits Breakdown Program Sponsorship Program Sponsor Price (USD) 25,000-30,000 Number of Registrations Recognition on Conference Website, Materials and Signage Advertisement in Conference Program Acces to BIO One-on-One Partnering Partnering Suite and Priority Scheduling of Meetings Guaranteed Speaking Opportunity 3 Company Presentations Sponsor 20,000 3 Networking Opportunities Welcome Reception Sponsor 17,500 2 Hospitality Sponsor 15,000 2 Closing Reception Sponsor 12,500 2 BIO SPARK Showcase Reception Sponsor 12,500 2 Tabletop Exhibit Sponsor 7,500 1 Partnering & Social Media BIO One-on-One Partnering System Sponsor 20,000 3 Partnering Suite Package 17,500 2 Buzz of BIO Contest Sponsor 7,500 1 Social Media Sponsor 7,500 1 Promotional Opportunities Conference Bag Sponsor 17,500 2 Conference Program Sponsor 15,000 2 Lanyard Sponsor 15,000 2 WiFi Sponsor 12,500 2 Digital Daily Sponsor 7,500 1 Advertising Opportunities Branding Package 5,000 0 Conference Program Advertisement Conference Bag Insert 1, ,500 0 For more information, contact Matt Lowe, Vice President, Sales & Sponsorship at sponsor@bio.org 6

7 Back to Benefits Breakdown Program Sponsorship PROGRAM SPONSOR Subject to Availability...$25,000 - $30,000 USD Three (3) complimentary registrations One (1) guaranteed speaking opportunity on program (to be determined based on program development) One (1) dedicated partnering suite to be used for BIO One-on-One Partnering meetings Dedicated BIO staff to provide support and optimize scheduling of BIO One-on-One Partnering meetings Access to BIO One-on-One Partnering COMPANY PRESENTATIONS SPONSOR Exclusive...$20,000 USD Sponsor recognition on company presentation signage and materials Ability to introduce up to fifteen (15) company presentations Access to BIO One-on-One Partnering 7

8 Back to Benefits Breakdown Networking Opportunities WELCOME RECEPTION SPONSOR Exclusive... $17,500 USD Sponsor recognition at Welcome Reception Five (5) tickets for guests to attend the Welcome Reception Access to BIO One-on-One Partnering HOSPITALITY SPONSOR Exclusive...$15,000 USD Sponsor recognition during breakfasts, lunches and breaks Access to BIO One-on-One Partnering CLOSING RECEPTION SPONSOR Exclusive...$12,500 USD Sponsor recognition at Closing Reception Three (3) tickets for guests to attend the Closing Reception Access to BIO One-on-One Partnering BIO SPARK SHOWCASE RECEPTION SPONSOR Exclusive...$12,500 USD for the BIO Investor Forum Note: Registration to BIO Investor Forum provides complimentary access to BIO SPARK Showcase Sponsor recognition at BIO SPARK Showcase Reception Three (3) tickets for guests to attend the BIO SPARK Showcase Reception Access to BIO One-on-One Partnering TABLETOP EXHIBIT SPONSOR Three (3) Available...$7,500 USD One (1) complimentary registration One (1) dedicated 6 tabletop exhibit space within the main congregating area of the conference (Includes table and two chairs. Tablecloth and promotional materials to be provided by the sponsor.) 8

9 Back to Benefits Breakdown Partnering & Social Media BIO ONE-ON-ONE PARTNERING SYSTEM SPONSOR Exclusive...$20,000 USD Three (3) complimentary registrations Sponsor recognition on BIO One-on-One Partnering system, partnering terminals and printed partnering schedules One (1) dedicated partnering suite to be used for BIO One-on-One Partnering meetings Dedicated BIO staff to provide support and optimize scheduling of BIO One-on-One Partnering meetings Access to BIO One-on-One Partnering PARTNERING SUITE PACKAGE Subject to Availability... $17,500 USD One (1) dedicated partnering suite to be used for BIO One-on-One Partnering meetings Dedicated BIO staff to provide support and optimize scheduling of BIO One-on-One Partnering meetings Access to BIO One-on-One Partnering BUZZ OF BIO CONTEST SPONSOR Exclusive...$7,500 USD Sponsor recognition on Buzz of BIO webpage and on all contest materials BIO to recognize sponsor in two (2) dedicated Buzz of BIO tweets and in promotion for the contest Ability to introduce Buzz of BIO winner during their company presentation SOCIAL MEDIA SPONSOR Exclusive...$7,500 USD One (1) complimentary registration Pre-conference social media collaborations and co-promotion with BIO (content to be developed by BIO and sponsor) Dedicated tweets during the conference with links to sponsor s website with visibility to 2,800 followers 9

10 Back to Benefits Breakdown Promotional Opportunities CONFERENCE BAG SPONSOR Exclusive... $17,500 USD SOLD Sponsor recognition on conference bags (conference and/or BIO logo also included); conference bags distributed to conference attendees Access to BIO One-on-One Partnering CONFERENCE PROGRAM SPONSOR Exclusive...$15,000 USD Sponsor recognition on front cover of conference program One (1) full-page advertisement on inside front cover of conference program Access to BIO One-on-One Partnering LANYARD SPONSOR Exclusive...$15,000 USD SOLD Sponsor recognition on lanyards; lanyards distributed to conference attendees Access to BIO One-on-One Partnering WIFI SPONSOR Exclusive...$12,500 USD Sponsor recognition on the WiFi login page and custom redirect to URL of sponsor s choosing Sponsor recognition and WiFi login information placed on the back of attendee registration badges Access to BIO One-on-One Partnering DIGITAL DAILY SPONSOR Exclusive...$7,500 USD Sponsor recognition on Digital Daily, an e-newsletter sent to 30,000 event prospects, including all conference registrants and media, covering the event highlighting buzz-worthy news, videos, and photos each day of the conference 10

11 Back to Benefits Breakdown Advertising Opportunities BRANDING PACKAGE Multiple Available... $5,000 USD One (1) full-page corporate promotional flyer to be included in all conference bags (flyer to be provided by sponsor and at the cost of the sponsor) CONFERENCE BAG INSERT Multiple Available...$1,500 USD One (1) full-page corporate promotional flyer to be included in all conference bags (flyer to be provided by sponsor and at the cost of the sponsor) CONFERENCE PROGRAM ADVERTISEMENT Multiple Available...$1,500 USD For more information, contact Matt Lowe, Vice President, Sales & Sponsorship at 11

12 2018 Sponsors DOUBLE HELIX SPONSORS HELIX SPONSOR SUPPORTING BANK SPONSORS CONFERENCE SPONSORS LOCAL CO-HOST REGIONAL CO-HOSTS 12

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