Supplementary Table S1. Supplement categories
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1 Supplementary Table S1. Supplement categories 28 categories 1 Multivitamin and/or multimineral 2 Multivitamin and/or multimineral, with herbal extracts 3 Calcium supplements 4 Magnesium supplements 5 Zinc supplements 6 Other single mineral supplements 7 Vitamin C supplements 8 Vitamin E supplements 9 Folic acid supplements 10 Vitamin D supplements 11 Other single vitamin supplements 12 Fish oil supplements 13 Fish oil supplements with added nutrients 14 Cod liver oil supplements 15 Evening primrose oil supplements 16 Other lipid supplements 17 Herbal supplements 18 Herbal supplements containing caffeine 19 Fibre supplements 20 Protein or amino acid supplements 21 Probiotic supplements 22 Sports or weight control supplements 23 Homoeopathic supplements 24 Herbal medicines, topical or inhalation 25 Propolis or other bee product supplements 26 Glucosamine and/or chondroitin based 27 Coenzyme Q10 supplements 28 Other supplements
2 Supplementary Table S2. Characteristics of supplement users and non-users among adults aged 18 years participating in the National Health Survey (n=14,560) Supplement user Supplement non-user Row Row n (95 CI) 1 n (95 CI) 1 Sex (42, 44) (56, 58) Male (34, 36) (64, 66) Female (49, 52) (48, 51) Age group years (34, 38) (62, 66) years (39, 42) (58, 61) years (45, 48) (52, 55) 70 years (47, 52) (48, 53) Region of birth Australia (41, 44) (56, 59) Main English-speaking countries (41, 47) (53, 59) Other (43, 48) (52, 57) State/Territory New South Wales (41, 45) (55, 59) Victoria (41, 45) (55, 59) Queensland (42, 46) (54, 58) South Australia (41, 46) (54, 59) Western Australia (42, 46) (54, 58) Tasmania (40, 45) (55, 60) Northern Territory (31, 38) (62, 69) Australian Capital Territory (44, 49) (51, 56) Socioeconomic status Lowest quintile (38, 43) (57, 62) Second quintile (40, 44) (56, 60) Third quintile (42, 46) (54, 58) Fourth quintile (42, 46) (54, 58) Highest quintile (44, 49) (51, 56) Education Postgraduate (44, 50) (50, 56) Bachelor/Diploma (47, 51) (49, 53) Certificate (39, 43) (57, 61) None after school (38, 41) (59, 62) BMI category Underweight (37, 53) (47, 63) Normal weight (44, 47) (53, 56) Overweight (41, 44) (56, 59) Obese (39, 43) (57, 61) Physical activity
3 Low (41, 43) (57, 59) Moderate (43, 46) (54, 57) High (44, 49) (51, 56) Smoking Current smoker (30, 35) (65, 70) Past smoker (44, 47) (53, 56) Never smoked (44, 46) (54, 56) Self-assessed health Excellent (42, 46) (54, 58) Very good (43, 46) (54, 57) Good (41, 44) (56, 59) Fair (39, 45) (55, 61) Poor (38, 46) (54, 62) Health condition Yes (43, 45) (55, 57) No (31, 45) (55, 69) 1 Percentages weighted to the Australian population in 2014/2015
4 Supplementary Table S3. Characteristics of supplement users and non-users among adolescents aged years participating in the National Health Survey (n=1,964) Supplement user Supplement non-user Row Row n (95 CI) 1 n (95 CI) 1 Sex (18, 22) (78, 82) Male (17, 23) (77, 83) Female (18, 24) (76, 82) Region of birth Australia (18, 22) (78, 82) Main English-speaking countries (14, 32) (68, 86) Other (14, 29) (71, 86) State/Territory New South Wales (15, 23) (77, 85) Victoria (16, 25) (75, 84) Queensland (14, 22) (78, 86) South Australia (12, 21) (79, 88) Western Australia (21, 32) (68, 79) Tasmania 5 25 (19, 32) (68, 81) Northern Territory (6, 18) (82, 94) Australian Capital Territory (17, 30) (70, 83) Socioeconomic status Lowest quintile (11, 21) (79, 89) Second quintile (15, 24) (76, 85) Third quintile (14, 23) (77, 86) Fourth quintile (17, 26) (74, 83) Highest quintile (19, 29) (71, 81) BMI category Underweight (9, 25) (75, 91) Normal weight (19, 24) (76, 81) Overweight (13, 20) (80, 87) Obese (15, 31) (69, 85) Health condition Yes (20, 26) (74, 80) No (6, 23) (77, 94) 1 Percentages weighted to the Australian population in 2014/2015
5 Supplementary Table S4. Characteristics of supplement users and non-users among children aged 9 years participating in the National Health Survey (n=2,733) Supplement user Supplement non-user Row Row n (95 CI) 1 n (95 CI) 1 Sex (22, 25) (75, 78) Male (22, 27) (73, 78) Female (20, 25) (75, 80) State/Territory New South Wales (21, 29) (71, 79) Victoria (20, 28) (72, 80) Queensland (20, 28) (72, 80) South Australia (11, 19) (81, 89) Western Australia (20, 29) (71, 80) Tasmania (15, 25) (75, 85) Northern Territory (14, 26) (74, 86) Australian Capital Territory (10, 19) (81, 90) Socioeconomic status Lowest quintile (19, 28) (72, 81) Second quintile (19, 28) (72, 81) Third quintile (15, 23) (77, 85) Fourth quintile (21, 29) (71, 79) Highest quintile (22, 31) (69, 78) 1 Percentages weighted to the Australian population in 2014/2015
6 Supplementary Table S5. Prevalence of use of different supplement types by participants in the National Health Survey (n=19,257) Age (years) n All Total (95 CI) 1 (95 CI) 1 (95 CI) 1 (95 CI) 1 (95 CI) 1 (95 CI) 1 (95 CI) 1 All supplements 23.5 (2, 25.4) 2 (18.1, 22.2) 36.1 (33.8, 38.5) 4 (39.0, 42.1) 46.8 (45.1, 48.4) 49.5 (47.1, 51.9) 38.0 (37.2, 38.8) Multivitamin/mineral 12.4 (1, 13.9) 1 (8.5, 1) 19.0 (17.1, 2) 22.3 (2, 23.6) 18.3 (17.0, 19.5) 16.7 (14.9, 18.5) 17.5 (16.9, 18.2) Multivitamin/mineral, with herbal extracts (, ) (, ) 1.9 (, 2.6) (, 2.1) (, 2.2) (, 2.3) 1.5 (, ) Calcium (, ) (0.02, ) (, 1.9) 2.5 (2.0, 3.0) 6.2 (5.4, 6.9) 9.6 (8.2, 1) 3.6 (3.3, 3.9) Magnesium (0.03, ) (, ) 2.3 (, 3.0) 3.3 (2.8, 4.0) 6.0 (5.2, 6.7) 6.9 (5.6, 8.1) 3.6 (3.3, 3.9) Zinc (0.000, ) (0.000, ) (, ) (, ) (, ) (0.003, ) (, ) Other single mineral (0.000, ) (0.000, ) (, ) (, ) (, ) (, 2.5) (, ) Vitamin C 3.2 (2.4, 3.9) 5.0 (3.9, 6.2) 6.5 (5.3, 7.7) 5.2 (4.5, 5.9) 5.1 (4.4, 5.8) 3.7 (2.8, 4.6) 4.9 (4.5, 5.2) Vitamin E (0.000, ) - (0.000, ) (, ) (, 1.5) (, 1.9) (, ) Folic acid - - (, ) (, ) (, ) (, ) (, ) Vitamin D (, ) (, 1.9) 3.4 (2.6, 4.3) 6.3 (5.5, 7.0) 1 (1, 12.2) 16.2 (14.5, 18.0) 7.1 (6.6, 7.5) Other single vitamin (0.002, ) Fish oil 5.2 (4.2, 6.2) (, ) 4.1 (3.1, 5.1) (, ) 6.0 (4.9, 7.2) (, 2.0) 7.2 (6.5, 8.0) (, 2.8) 14.8 (13.6, 15.9) (, 2.8) 14.3 (12.6, 16.0) (, ) 9.2 (8.7, 9.6)
7 Fish oil with added nutrients (, ) (, ) (, ) Cod liver oil (0.000, ) (0.000, ) (0.000, ) Evening primrose oil - (0.03, ) (0.03, ) Other lipid (0.000, ) (0.05, ) (, ) Herbal (, 1.9) (1.5, 3.0) (3.7, 5.7) Herbal containing - - caffeine (0.000, ) Homeopathic (, ) (0.000, ) (0.02, ) Herbal medicines, topical or inhalation (, ) (0.000, ) (, ) Fibre (0.000, ) (0.000, ) (0.04, ) Protein or amino acid 2.0 (0.000, ) (, ) (, 2.7) Sports or weight control 2.0 (0.000, ) (0.000, ) (, 2.6) Probiotic (2.1, 3.6) (, ) (, 3.1) Propolis or other bee - product (0.000, ) (0.000, ) Glucosamine and/or 0.01 chondroitin (0.000, 0.02) (0.000, ) (, ) Coenzyme Q (, ) Other (0.000, ) (0.000, ) (0.05, ) (, ) (, ) (, ) (, ) 7.0 (6.2, 7.8) (0.04, ) (, ) (, ) (, ) 1.5 (, 1.9) (, ) 2.5 (2.0, 3.0) (, ) 2.0 (, 2.4) (, ) (, ) (, ) (, ) (, ) 3.7 (3.1, 4.3) 8.4 (7.5, 9.3) (0.01, ) (0.03, ) (, ) (, ) (, ) (, ) 2.1 (, 2.6) (, ) 7.4 (6.6, 8.3) (, 2.2) (, ) (, ) (, ) (0.000, ) 2.6 (1.9, 3.4) 7.0 (5.8, 8.3) (0.000, ) 0.04 (0.000, ) (0.000, ) (, ) (0.03, ) (0.000, ) (, 2.2) (0.000, ) 8.1 (6.8, 9.4) 2.0 (, 2.7) (, ) (, ) (, ) (, ) (1.5, 1.9) 5.8 (5.4, 6.2) (0.04, ) (, ) (, ) (, ) (, ) (, ) 2.2 (1.9, 2.4) (, ) 3.4 (3.1, 3.7) (, ) (, ) Males
8 n (95 CI) (95 CI) (95 CI) (95 CI) (95 CI) (95 CI) (95 CI) All supplements 24.4 (2, 27.1) 19.7 (16.8, 22.5) 29.3 (26.2, 32.4) 33.3 (3, 35.5) 37.2 (34.8, 39.5) 39.7 (36.1, 43.3) 3 (3, 32.6) Multivitamin/mineral 13.2 (1, 15.3) 9.3 (7.3, 1) 14.5 (12.1, 16.8) 17.8 (16.0, 19.5) 13.4 (1, 15.0) 11.9 (9.5, 14.3) 13.9 (13.1, 14.7) Multivitamin/mineral, with herbal extracts (, ) (0.01, ) (, 2.0) (, ) (, 1.5) (, ) (, ) Calcium (, ) (0.000, ) (, 2.1) (, 2.0) 2.6 (, 3.4) 5.4 (3.6, 7.1) (1.5, 2.2) Magnesium (0.000, ) (0.04, ) (, 2.6) 2.4 (, 3.2) 4.1 (3.1, 5.1) 5.4 (3.7, 7.1) 2.5 (2.1, 2.9) Zinc (0.000, ) (0.000, ) (, ) (, ) (, ) (0.000, ) (, ) Other single mineral (0.000, ) (0.000, ) (0.000, ) (0.000, ) (, ) (, 2.4) (, ) Vitamin C 3.6 (2.4, 4.7) 5.2 (3.6, 6.9) 6.3 (4.7, 8.0) 5.1 (4.0, 6.1) 4.2 (3.2, 5.2) 3.4 (2.0, 4.7) 4.6 (4.1, 5.1) Vitamin E (0.000, ) - (0.000, ) (0.01, ) (, 1.5) (, 1.5) (, ) Folic acid - - (0.000, ) (0.000, ) (0.003, ) (0.02, ) (, ) Vitamin D (, 2.1) (0.03, ) (, 2.7) 4.0 (3.1, 4.9) 5.5 (4.4, 6.6) 9.3 (7.3, 1) 3.8 (3.4, 4.3) Other single vitamin (0.000, ) (0.000, ) (, ) (, ) (, 2.4) 2.4 (, 3.5) (, ) Fish oil 6.4 (4.9, 7.9) 5.0 (3.5, 6.5) 5.9 (4.3, 7.5) 7.0 (5.8, 8.1) 13.2 (1, 14.8) 1 (8.8, 13.2) 8.5 (7.8, 9.2) Fish oil with added nutrients (, 1.5) (0.02, ) 0.02 (0.000, 0.05) (0.01, ) (, ) (, ) (, ) Cod liver oil (0.000, ) (0.000, ) - (0.000, ) (0.02, ) (0.000, ) (, ) Evening primrose oil
9 (0.000, ) (0.000, ) (0.000, 0.01) (0.01, ) (0.000, ) (0.03, ) Other lipid (0.000, ) (0.000, ) (, ) (, ) 2.5 (, 3.3) 2.2 (, 3.3) (, ) Herbal (, 2.1) (, 2.5) 3.4 (2.2, 4.5) 4.7 (3.7, 5.6) 5.2 (4.1, 6.3) 6.7 (4.8, 8.5) 4.0 (3.5, 4.4) Herbal containing caffeine - - (0.000, ) (0.000, ) (0.000, ) - (0.02, ) Homeopathic (, ) (0.000, ) (0.000, ) (0.000, ) 0.03 (0.000, ) - (, ) Herbal medicines, topical or inhalation (, ) (0.000, ) (0.000, ) (0.000, ) (, ) (0.000, ) (, ) Fibre (0.000, ) (0.000, ) (0.000, ) (, ) (, ) - (, ) Protein or amino acid (0.000, ) (, ) 2.9 (, 4.0) (, 2.2) (, ) (0.000, ) (, ) Sports or weight control (0.000, ) (0.000, ) 3.1 (1.9, 4.2) (, ) (0.03, ) (0.000, ) (, ) Probiotic 2.7 (, 3.7) (, ) (, 2.5) (, ) (, ) (, 2.6) (, ) Propolis or other bee product (0.000, ) - - (0.000, ) (0.000, ) (0.000, ) (, ) Glucosamine and/or chondroitin 0.01 (0.000, 0.04) (0.000, ) (, ) 2.5 (, 3.2) 6.1 (5.0, 7.3) 6.4 (4.6, 8.2) 2.9 (2.5, 3.3) Coenzyme Q (0.000, ) (, ) 1.5 (, 2.1) (, 2.6) (, ) Other - - (0.000, ) (, ) (, ) (, 2.0) (, ) Females n (95 CI) (95 CI) (95 CI) (95 CI) (95 CI) (95 CI) (95 CI) All supplements 22.5 (19.9, 25.2) 2 (17.6, 23.6) 42.5 (39.2, 45.9) 46.1 (44.0, 48.2) 55.2 (53.0, 57.5) 57.5 (54.3, 6) 43.9 (42.7, 45.1)
10 Multivitamin/mineral 11.5 (9.5, 13.5) 1 (8.5, 13.2) 23.2 (2, 26.0) Multivitamin/mineral, 2.6 with herbal extracts (, ) (, ) (1.5, 3.7) Calcium (, ) (0.000, ) (, 2.2) Magnesium 2.9 (0.000, ) (, ) (, 4.0) Zinc (0.000, ) (0.000, ) (0.03, ) Other single mineral 0.03 (0.000, ) (0.000, ) (, 2.1) Vitamin C (, 3.7) (3.2, 6.4) (5.0, 8.4) Vitamin E - (0.000, ) (0.000, ) Folic acid - - (, 2.0) Vitamin D (, 1.9) (, 3.3) (3.5, 6.5) Other single vitamin (0.000, ) (0.002, ) (, 1.5) Fish oil (2.7, 5.1) (1.9, 4.4) (4.6, 7.8) Fish oil with added 1.5 nutrients (, 2.3) (, ) (, 2.2) Cod liver oil - - (0.000, ) Evening primrose oil - (0.01, ) (0.01, ) Other lipid - (0.000, ) (, ) Herbal (, 2.1) (, 4.2) (4.4, 7.5) 25.8 (24.0, 27.6) 2.4 (, 3.0) 3.4 (2.6, 4.1) 4.1 (3.3, 5.0) (, ) (, ) 5.3 (4.3, 6.2) (, ) (, ) 8.0 (6.9, 9.1) 2.2 (1.5, 2.8) 7.5 (6.4, 8.5) 1.5 (, 2.0) (, ) (, ) (, ) 8.7 (7.6, 9.9) 22.6 (2, 24.4) 2.4 (, 3.1) 9.3 (8.0, 1) 7.6 (6.4, 8.7) (, ) (, 2.2) 5.9 (4.8, 6.9) (, ) (, ) 16.2 (14.6, 17.9) 2.8 (2.0, 3.6) 16.1 (14.5, 17.7) (, ) (, ) (, ) 4.7 (3.8, 5.7) 1 (9.8, 12.7) 2 (18.0, 23.2) 2.1 (, 3.1) 13.0 (1, 15.2) 8.1 (6.3, 9.8) (0.000, ) 2.1 (, 3.1) 4.0 (2.7, 5.3) (, 2.7) (, ) 2 (19.2, 24.5) 1.9 (, 2.7) 17.0 (14.5, 19.4) (, ) (, ) (0.000, ) 3.0 (1.9, 4.0) 7.3 (5.7, 9.0) 2 (19.9, 2) 2.0 (, 2.3) 5.1 (4.6, 5.6) 4.5 (4.0, 5.0) (, ) (, ) 5.1 (4.6, 5.6) (, ) (, ) 10.0 (9.3, 1) (, 2.1) 9.8 (9.1, 1) (, ) (, ) (, ) 2.0 (, 2.3) 7.4 (6.8, 8.0)
11 Herbal containing caffeine (0.000, 0.05) Homeopathic - (, ) (0.000, ) Herbal medicines, topical - or inhalation (0.000, ) (0.000, ) Fibre - (0.000, ) (0.000, ) Protein or amino acid 0.03 (0.000, ) (0.000, ) (, 2.0) Sports or weight control - - (, ) Probiotic (2.0, 4.1) (, 1.5) (1.9, 4.3) Propolis or other bee - - product (0.000, ) Glucosamine and/or - - chondroitin (, ) Coenzyme Q (, ) Other (0.000, ) (0.000, ) (0.000, ) (0.004, ) (, ) (, ) (, ) (, 1.9) (, ) 3.6 (2.8, 4.4) (0.002, ) (, 2.1) (, ) (, ) (0.000, ) (0.03, ) (, ) (, ) (, ) (, ) 3.3 (2.5, 4.0) (, ) 8.6 (7.3, 9.8) 1.9 (, 2.6) (, ) (0.000, ) (0.000, ) (0.000, ) (, ) (0.000, ) (0.000, ) (, 2.3) (0.000, ) 9.4 (7.5, 1) 2.2 (, 3.3) (, ) (0.03, ) (, ) (, ) (, ) (, ) (, ) 2.9 (2.5, 3.2) (, ) 3.8 (3.4, 4.3) (, ) (, ) 1 Percentages weighted to the Australian population in 2014/2015
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