Xin Liu. Missouri University of Science and Technology, Rolla, MO Assistant Professor Nuclear Engineering Program

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1 Xin Liu Assistant Professor Nuclear Engineering Missouri University of Science and Technology 223 Fulton Hall 301 W 14 th St. Rolla, MO (573) (phone) xinliu@mst.edu EDUCATION University of Wisconsin, Madison, WI PhD in Nuclear Engineering & Engineering Physics 2003 Dissertation: Flow Visualization and Void Fraction Measurement i n Liquid- Metal/Water Direct Contact Heat Exchange by X-ray Attenuation Technique Advisor: Michael L. Corradini Committee: James P. Blanchard, Riccardo Bonazza, Charles A. Mistretta, Tim Shedd Jiaotong University, Xi an, China MS in Nuclear Engineering 1997 Thesis: Design of Neutron-Neutron Well Logging Numerical Simulation Integrate System and Research on the Neutron-Gamma Well Logging Advisor: Banghua Yin Committee: Zhongsheng Xie, Hongchun Wu, Jizhou Zhu, Jianmin Zhang Jiaotong University, Xi an, China BS in Nuclear Engineering 1994 Minor: Computer Science Honors Thesis: In-Core Fuel Management Software Transportation from UNIX Workstation to Desktop PC WORK EXPERIENCE Missouri University of Science and Technology, Rolla, MO Assistant Professor Nuclear Engineering Program GE Healthcare, Waukesha, WI Scientist Advanced Science and Engineering Mayo Clinic, Rochester, MN Research Fellow 2007 Senior Research Fellow 2008 Research Associate 2009 CT Clinical Innovation Center, Department of Radiology Argonne National Laboratory, Argonne, IL Postdoctoral Fellow Advanced Photon Source Division 2011-present

2 RESEARCH INTEREST Quantitative X-ray/Neutron Imaging, Advanced Computed Tomography Reconstruction (Fourier transform based and statistical methods), Image Processing. Radiation Detection, Dosimetry, and Biology Monte Carlo Simulation Nuclear Well Logging PATENT US 7,885,373 B2 System and Method for Quantitative Imaging of Chemical Composition to Decompose Multiple Materials BOOK CHAPTER C.H. McCollough, B. Schmidt, X. Liu, L. Yu, S. Leng, Dual energy algorithms and post processing techniques, In: Dual Energy CT in Clinical Practice, T. Johnson et al. (Eds.), Springer PEER-REVIEWED AND INVITED PUBLICATION 1. Hua Li, Lifeng Yu, Xin Liu, Joel G. Fletcher, Cynthia H. McCollough, Metal Artifact Suppression from Reformatted Projections in Multi-slice Helical CT using Dual-front Active Contours, Medical Physics, vol , Xin Liu, Andrew N. Primak, James D. Krier, Lifeng Yu, Lilach O. Lerman, Cynthia H. McCollough, Accurate, In Vivo Determination of Renal Perfusion and Hemodynamics using a Ten-Fold Decrease in Radiation Dose and HYPR Noise Reduction, Radiology, 253:98-105, Xin Liu, Lifeng Yu, Andrew N. Primak, Cynthia H. McCollough, Quantitative imaging of element composition and mass fraction using dual-energy CT: Three material decomposition, Medical Physics, vol. 36(5): , Xin Liu, Kyoung-Su Im, Yujie Wang, Jin Wang, Mark W. Tate, Alper Ercan, Daniel R. Schuette, Sol M. Gruner, Four Dimensional Visualization of Highly Transient Fuel Sprays by Microsecond Quantitative X-ray Tomography, Applied Physics Letter, 94, , Lifeng Yu, Xin Liu, Shuai Leng, et al. Radiation dose reduction in CT: Techniques and future perspective, (Invited review article), Imaging in Medicine, Vol , Hua Li, Lifeng Yu, Xin Liu, Cynthia H. McCollough, Metal Artifact Suppression from Reformatted Projections in Multi-slice Helical CT using Dual-front Active Contours, (Invited session paper), 31 st IEEE EMBS Conference, Lifeng Yu, Andrew N. Primak, Xin Liu, Cynthia H. McCollough, Image Quality Optimization and Evaluation of Linearly-Mixed Images in Dual-

3 Source, Dual-Energy CT, Medical Physics, vol. (36)3: , Andrew N. Primak, J.C. Ramirez Giraldo, Xin Liu, Lifeng Yu, Cynthia H. McCollough, Optimal Spectral Filtration for Dual-Energy and Dual-Source CT, Medical Physics, vol. (36)4: , Kyoung-Su Im, Seong-Kyun Cheong, Xin Liu, Jin Wang, M.-C. Lai, Mark W. Tate, Alper Ercan, Matt J. Renzi, Daniel R. Schuette, Sol M. Gruner, Interaction between supersonic disintegrating liquid jets and their shock waves, Physical Review Letters, 102, , Lifeng Yu, Hua Li, Jan Muller, James M. Kofler, Xin Liu, Andrew N. Primak, Joel G. Fletcher, Thanila Macedo, Cynthia H. McCollough, Metal artifact reduction from reformatted projections in multi-slice helical CT: Techniques and initial clinical results, Investigative Radiology, vol , Yujie Wang, Xin Liu, Kyoung-Su Im, Wak-Keat Lee, Jin Wang, Kamel Fezzaa, David L.S. Hung, James R. Winkelman, Ultrafast X-ray Study of Dense- Liquid-Jet Flow Dynamics using Structure-Tracking Velocimetry, Nature Physics, 4, , Alan Kastengren, Christopher F. Powell, Thomas Riedel, Seong-Kyun Cheong, Kyoung-Su Im, Xin Liu, Yujie Wang, Jin Wang, Nozzle Geometry and Injection Duration Effects on Diesel Sprays Measured by X-Ray Radiography, J. of Fluids Engineering, Vol 130, , Xin Liu, Kyoung-Su Im, Yujie Wang, Jin Wang, Makr W. Tate, Alper Ercan, Daniel R. Schuette, Sol M. Gruner, Ultrafast and Quantitative X- Tomography and Simulation of Hollow-Cone Gasoline Direct-Injection Sprays, SAE Transactions J. of Fuels and Lubricants, Vol 116, p309, Kyoung-Su Im, Kamel Fezzaa, Yujie Wang, Xin Liu, Jin Wang, Particle Tracking Velocimetry using Fast X-ray Phase-Contrast Imaging, Applied Physics Letter, 90, , Alan Kastengren, Christopher F. Powell, Thomas Riedel, Seong-Kyun Cheong, Yujie Wang, Kyoung-Su Im, Xin Liu, Jin Wang, Determination of Diesel Spray Axial Velocity Using X-ray Radiography, SAE Special Publication Diesel Fuel Injection and Sprays, , Xin Liu, Kyoung-Su Im, Yujie Wang, Jin Wang, David L.S. Hung, James R. Winkelman, Mark W. Tate, Alper Ercan, Lucas J. Koerner, Thomas Caswell, Darol Chamberlain, Daniel R. Schuette, Hugh Philipp, Detlef M. Smilgies, Sol M. Gruner, Quantitative Characterization of Near-Field Fuel Sprays by Multi- Orifice Direct Injection Using Ultrafast X-Tomography Techniques, SAE Transactions J. of Engine, Vol 115, P576, Sherif Abdulla, Xin Liu, Mark H. Anderson, Riccardo Bonazza, Michael L. Corradini, Dae Cho, Richard Page, Liquid-Metal/Water Direct Contact Heat Exchange: Flow Visualization, Flow Stability, and Heat Transfer Using Real - Time X-Ray Imaging, Nuclear Science and Engineering 150, P , 2005.

4 18. Xin Liu, Jinyuan Liu, Xuefa Li, Seong-Kyun Cheong, Deming Shu, Jin Wang, Mark W. Tate, Alper Ercan, Daniel R. Schuette, Matt J. Renzi, Arthur Woll, Sol M. Gruner, Development of Ultrafast Computed Tomography of Highly Transient Fuel Sprays, (Invited Paper) Proceedings of SPIE Vol. 5535, SPIE 49 th Annual Meeting, Denver, Xin Liu, Hongchun Wu, Aizhong Yue, Zhenqian Zhong, Neutron-Neutron Logging Numerical Simulation Integrated System, Well Logging Technology, 22(4), P , CONFERENCE PROCEEDING, PAPER, AND ABSTRACT Xin Liu, Lifeng Yu, Armando Manduca, Erik L. Ritman, Cynthia H. McCollough, A super resolution technique for clinical multislice CT, SPIE Medical Imaging, Vol. 7622, Xin Liu, Andrew N. Primak, Lifeng Yu, Hua Li, Cynthia H. McCollough, James D. Krier, Lilach O. Lerman, Quantitative evaluation of noise reduction algorithms for very low dose renal CT perfusion imaging, SPIE Medical Imaging, Vol. 7258, Lifeng Yu, Xin Liu, Cynthia H. McCollough, Pre-reconstruction threematerial decomposition in dual-energy CT, SPIE Medical Imaging, Vol. 7258, Shuai Leng, Xin Liu, Lifeng Yu, Thomas D. Atwell, Cynthia H. McCollough, Radiation dose reduction in CT guided cryoablation using HYPR-LR AAPM, Hua Li, Lifeng Yu, Xin Liu, Cynthia H. McCollough, A novel boundary tracking method for metal artifact suppression in helical CT imaging AAPM, Xin Liu, Lifeng Yu, Andrew N. Primak, Cynthia H. McCollough, Experimental Validation of Three-Material Mass-Fraction Decomposition RSNA, Xin Liu, Andrew N. Primak, James D. Krier, Lifeng Yu, Lilach O. Lerman, Cynthia H. McCollough, Accurate, In Vivo Determination of Renal Perfusion and Hemodynamics Using HYPR Noise Reduction and Ten-Fold Decrease in Radiation Dose, RSNA, Xin Liu, Lifeng Yu, Andrew N. Primak, Cynthia H. McCollough, A General Three-Material Quantification Method using Dual-Energy CT Imaging, AAPM, Xin Liu, Andrew N. Primak, Vanessa Zavaletta, Lifeng Yu, Cynthia H. McCollough, Evaluation of Noise Reduction Methods On Very Low Dose CT Renal Perfusion Imaging, AAPM, Xin Liu, Andrew N. Primak, Lifeng Yu, Cynthia H. McCollough, Richard L.

5 Morin, Quantitative Imaging of Chemical Composition using Dual-Energy, dual-source CT, SPIE Medical Imaging, , Juan C. Ramirez Giraldo, Andrew N. Primak, Xin Liu, Lifeng Yu, Cynthia H. McCollough, Optimal Spectral Filtration Can Improve Dual-Energy Material Discrimination Using Dual-Source CT, RSNA, Lifeng Yu, James M. Kofler, Xin Liu, Andrew N. Primak, Cynthia H. McCollough, Automatic Metal Artifact Reduction from Reformatted Projections in Multi-Slice Helical CT, AAPM, Juan C. Ramirez Giraldo, Andrew N. Primak, Xin Liu, Cynthia H. McCollough, X-ray Spectra Optimization for Dual-Energy Imaging using Dual-Source CT, AAPM, R. Raupach, H. Bruder, A.N. Primak, X. Liu, C.H. McCollough, B. Schmidt, T.G. Flohr, Dose Reduction Strategies for CT Cardiac Imaging, SCCT, E.E. Williamson, J. Kirsch, A. Primak, X. Liu, P.A. Araoz, C.H. McCollough, Optimizing Image Quality Based on Body Mass Index and Heart Rates: A Novel Technique for Variable Temporal Resolution Reconstructions Using Cardiac Dual Source CT (DSCT), RSNA, L. Yu, A.N. Primak, O.P. Dzyubak, X. Liu, C.H. McCollough, Dual-Source Dual-Energy CT (DECT) Combined Images Can Provide Improved Image Quality Relative to Single-Energy CT with No Increase in Patient Dose, RSNA Kyoung-Su Im, Seong-Kyun Cheong, Xin Liu, Jin Wang, M.-C. Lai, Dynamics of the Shock Waves Generated by High-Speed Liquid Jets, Proceedings of ILASS Americas, 20 th Annual Conference, Chicago, Alan Kastengren, Christopher F. Powell, Yujie Wang, Kyoung-Su Im, Xin Liu, Seong-Kyun Cheong, Jin Wang, Thomas Riedel, Improved Method to Determine Spray Axial Velocity using X-ray Radiography, Proceedings of ILASS Americas, 20 th Annual Conference, Chicago, Xin Liu, Kyoung-Su Im, Yujie Wang, Jin Wang, David L.S. Hung, James R. Winkelman, Mark W. Tate, Sol M. Gruner, A Comparison of Three Direct- Injection High-Turbulence Multi-Orifice Nozzles by an Ultrafast X- Tomography Technique, Proceedings of ILASS Americas, 19 th Annual Conference, Toronto, Canada Seong-Kyun Cheong, Christopher F. Powell, Kyoung-Su Im, Xin Liu, Jin Wang, Effects of Nozzle Geometry on Cone Angles of High-Pressure Diesel Spray in Near-Nozzle Region, Proceedings of ILASS Americas, 19 th Annual Conference, Toronto, Canada Xin Liu, Seong-Kyun Cheong, Christopher F. Powell, Jin Wang, David L.S. Hung, James R. Winkelman, Mark W. Tate, Alper Ercan, Daniel R. Schuette,

6 Lucas J. Koerner, Sol M. Gruner, Near-Field Characterization of Direct Injection Gasoline Sprays from Multi-Hole Injector Using Ultrafast X- Tomography, Proceedings of ILASS Americas, 18 th Annual Conference, Irvine Corradini, Dae Cho, Richard Page Interfacial Transport Phenomena and Stability in Liquid-Metal/Water, Proceedings of 12 th International Heat Transfer Conference (IHTC-12), Volume 4, , won 2 nd prize, Grenoble, France, Corradini, Dae Cho, Richard Page Direct Contact Heat Exchange Interfacial Phenomena for Liquid-Metal Reactors, Proceedings of 10 th International Conference on Nuclear Engineering, (ICONE-10), Arlington, VA, Corradini, Dae Cho, Richard Page Interfacial Transport Phenomena and Stability in Liquid-Metal/Water Systems: Scaling Considerations, Proceedings of 9 th International Conference on Nuclear Engineering (ICONE- 9), Nice, France, Corradini, Dae Cho, Richard Page Local Heat Transfer Coefficient in Liquid Metal/Metal Bubbly Flow, Transactions of American Nuclear Society, 48, P , November, Corradini, Dae Cho, Richard Page Interfacial Transport Phenomena and Stability in Liquid-Metal/Water Systems: Visualization and Measurements of Void Fraction, Transactions of American Nuclear Society, 8, P46-48, November, 2001.

Research Support. Dual-Source CT: What is it and How Do I Test it? Cynthia H. McCollough, Ph.D.

Research Support. Dual-Source CT: What is it and How Do I Test it? Cynthia H. McCollough, Ph.D. Dual-Source CT: What is it and How Do I Test it? Cynthia H. McCollough, Ph.D. CT Clinical Innovation Center Department of Radiology Mayo Clinic College of Medicine Rochester, MN Research Support National