Pablo Artal. Adaptive Optics visual simulator ( and depth of focus) LABORATORIO DE OPTICA UNIVERSIDAD DE MURCIA, SPAIN

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1 Adaptive Optics visual simulator ( and depth of focus) Pablo Artal LABORATORIO DE OPTICA UNIVERSIDAD DE MURCIA, SPAIN 8th International Wavefront Congress, Santa Fe, USA, February

2 New LO UM building!

3 Diego Ayala Pedro Prieto Silvestre Manzanera Joe Lindacher Supported by: &

4 Aberration correction with Adaptive Optics Active element Aberrated eye Corrected eye + = + =

5 Phase manipulation with AO Visual simulation Active element Original eye Modified eye + = + =

6 Using the AO visual simulator to search for sxiii defocus better solutions for presbyopia using phase masks

7 Adding phase mask NO accommodation Strehl Defocus (D) Strehl Defocus (D)

8 Adaptive optics Spectra of Zernike modes with and without paralyzed accommodation for 4.7 mm pupil VISUAL SIMULATOR Interactive design/testing of new ophthalmic devices

9 Presbyopic corrector design procedure Phase profile design Prototype implementation Clinical testing Mass production

10 Presbyopic corrector design Phase profile design procedure Prototype implementation Adaptive optics visual simulator Clinical testing Mass production

11 Visual testin Stimuli g E generator? Subject Spatial light modulator H-S Induced phase

12 Active element: Liquid crystal programmable phase modulator Hamamatsu X8627 Advantages against deformable mirrors: _ High fidelity: no need of close-loop operation _ No continuity constrains: steep phase changes allowed _ High phase range (ideal for presbyopic zones)

13 Adaptive Optics Visual Simulator Cold mirror Hartmann-Shack Modulator Pupil Induced phase Polarizer CCD camera LASER 633 nm Spatial filter Pupil Focus / vergence control Diode laser 780 nm Beam splitter E Stimuli Generator Subject

14 Aberration measurement and coupling studies Cold mirror Hartmann-Shack Modulator Pupil Induced phase Polarizer CCD camera LASER 633 nm Spatial filter Pupil Focus / vergence control Diode laser 780 nm Beam splitter E Stimuli Generator Subject

15 Objective estimation of depth of focus Cold mirror Hartmann-Shack Modulator Pupil Induced phase Polarizer CCD camera LASER 633 nm Spatial filter Focus / vergence control Pupil Beam splitter Subject 0 Dp 1.4 Dp 2.8 Dp

16 Strehl Objective estimation of depth of focus Induced phase Bifocal profile LASER 633 nm Spatial filter Pupil Modulator Theoretical Experimental Defocus (Dp) Focus / vergence control Beam splitter Subject Polarizer Cold mirror Strehl Pupil Hartmann-Shack CCD camera Trifocal profile Dp Dp Dp Defocus (Dp) Theoretical Experimental

17 LO UM_AO_visual PHASE DESIGN SOFTWARE simulator GRAY-LEVEL IMAGE VISUAL TESTING e l i sm RELAYOPTICS SLM

18 Subjective depth of focus Cold mirror Hartmann-Shack Modulator Pupil Induced phase Polarizer CCD camera LASER 633 nm Spatial filter Pupil Focus / vergence control Diode laser 780 nm Beam splitter E Stimuli Generator Subject

19 Depth of focus with different phase 'x' size (min) no phase phase A phase B profiles Defocus (D) E

20 The best phases can be manufactured as contact lenses

21 Prototype checking E AOVS ON E AOVS OFF

22 Prototype checking (1/min) Readin mm pupil 3.6 mm pupil Subject: PA Estimulus vergence (D) Phase on actual contact lens Phase produced by the PPM in the AO system Subject: PA Stimulus vergence (Dp) agreement! Good

23 Conclusions Adaptive Optics used as simulator is a powerful tool to better understand how optics affects vision and to develop new and improved ophthalmic solutions In particular, we have demonstrated its potential to evaluate the depth of focus of

24 Conclusions The performance predicted with the AO system and that obtained with actual lenses were in quite a good agreement This AO approach can save several steps in current procedures for contact lens design and eventually lead to improved visual solutions

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