Q-value Adjusted Ablation PRK PRK. Allegretto Randomized control trial : .(Corneal asphericity) (PRK) Photo refractive keratectomy

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1 89/8/16 : 89/6/14 : 1389 /115 / Q-value Adjusted Ablation PRK PRK Allegretto Q-value adjusted PRK (PRK) Standard Photorefractive Keratectomy :. Allegretto Eye-Q 75. Randomized control trial : Allegretto Eye-Q Q-value adjusted PRK PRK /51 ± 1/22 10/48 ± 1/38 Q-value adjusted : Q-value adjusted 0 ± 0/37. -3/98 ± 1/66. 0/05 ± 0/ /86 ± 2/1.. Allegretto Eye-Q Q-value adjusted PRK :.. Photorefractive keratectomy :.(Corneal asphericity) Q = 0 Q-value Q >0 Q < 0 Oblate Prolate. Prolate Spherical aberration (PRK) Photo refractive keratectomy.. Sphericity amin1827@yahoo.co.nz : 909

2 3. 1 Contrast sensitivity (Low frequency) 6 cycle/s 10 (High frequency) 18 cycle/s Subjective refraction /3 86/ /2 ± 3/87 PRK. 36 Q-value adjusted. PRK PRK 10/21 ± 0/87 (BCVA) 10/48 ± 1/38 (UCVA).(P = 0/24) Q-value adjusted Oblate Steep.(1) Myopic PRK Oblate Corneal asphericity Optical. Q-value adjusted PRK Q-value Photoablation Q-value.(2-3) Q-value adjusted PRK PRK. Allegretto Eye-Q Randomized control trial 75. Anisometropia Myopic PRK. PRK. Qvalue adjusted PRK Allegretto eye- Q.. Wave Light 910

3 4/52 ± 0/98 Q-value.(P < 0/0001) 3/76 ± 1/17 adjusted 4/48 ± 0/78.(P < 0/0001) 6 cycle/sd Contrast sensitivity 18 cycle/s. Contrast sensitivity Contrast sensitivity PRK 4/22 ± 1/08 3/59 ± 1/14.(P < 0/0001) 18 Q value adjusted PRK 4/28 ± 0/99 4/03 ± 1/07.(P < 0/0001) Contrast sensitivity 18 cycles/s /04 ± 0/96 PRK 3/77 ± 1/77 2.(P = 0/13) 10/26 ± 0/92 10/51 ± 1/22 (UCVA).(P = 0/16) PRK 0/21 ± 1/59 Q-value adjusted PRK 0/24 ± 1/48 2.(P = 0/9) (BCVA) (P = 0/71) (UCVA).(P = 0/7) Subjective refraction PRK 0 ± 0/37-3/98 ± 1/66.(P < 0/0001) Subjective refraction Q-value adjusted PRK -3/86 ± 2/1 0/05 ± 0/3.(P < 0/0001) Subjective refraction. Contrast sensitivity Contrast sensitivity 6cycle/s 4/00 ± 1/64 911

4 Asphaic profile (High myopia) PRK Customized aspheric transition Zone.(7) (CATz) ablation algorithm Aspheric profile Conventional PRK. PRK Aspheric profile PRK Conventional Prolateness 6.(8) RPK Higher-order Aspheric profile. Spherical aberration aberration.(8) PRK Qvalue adjusted PRK Contrast sensitivity. Subjective refraction. PRK. Q-value adjusted PRK.. PRK (Safety).(4) Phtorefractive Glare PRK. Ghost image Haloes Ablation zone PRK. (3 6) Spherical aberration Higher-order aberration Spherical aberration Mid peripheral.(3 6) cornea Prolate Myopic PRK Spherical Oblate Q-. aberration Asphericity value adjusted PRK Sperical aberration PRK. 912

5 . PRK Allegretto. Q-value adjusted PRK.. Wave front guided PRK Aspheric profile PRK (9-10) -6-2/5.(9) Q-value 5 adjusted.(11) References 1. Bennett AG, Rabetts RB. Bennett and Rabbett's Clinical Visual Optics. 2 nd ed. London: Butter worths; MacRae S, Krueger R, Applegate RA, Editors. Customized Corneal Ablation: The Quest for SuperVision. 1 st ed. Thorofare, NJ: Slack Incorporated; Atebara NH, Editor Basic and Clinical Science Course Section 13: Refractive Surgery. San Francisco, LA: American Academy of Ophthalmology; Bricola G, Scotto R, Mete M, Cerruti S, Traverso CE. A 14-year follow-up of photorefractive keratectomy. J Refract Surg 2009; 25(6): Schallhorn SC, Blanton CL, Kaupp SE, Sutphin J, Gordon M, Goforth H Jr, et al. Preliminary results of photorefractive keratectomy in activeduty United States Navy personnel. Ophthalmology 1996; 103(1): Niesen UM, Businger U, Schipper I. Disability glare after excimer laser photorefractive keratectomy for myopi. J Refract Surg 1996; 12(2): S Vinciguerra P, Camesasca FI, Bains HS, Trazza S, Albè E. Photorefractive keratectomy for primary myopia using NIDEK topography-guided customized aspheric transition zone. J Refract Surg 2009; 25(1 Suppl): S Mastropasqua L, Toto L, Zuppardi E, Nubile M, Carpineto P, Di Nicola M, et al. Photorefractive keratectomy with aspheric profile of ablation versus conventional photorefractive keratectomy for myopia correction: six-month controlled clinical trial. J Cataract Refract Surg 2006; 32(1): Ghoreishi SM, Naderibeni A, Peyman A, Rismanchian A, Eslami F. Aspheric profile versus wavefront-guided ablation photorefractive keratectomy for the correction of myopia using the Allegretto Eye Q. Eur J Ophthalmol. 2009; 19(4): Stojanovic A, Wang L, Jankov MR, Nitter TA, Wang Q. Wavefront optimized versus custom-q treatments in surface ablation for myopic astigmatism with the WaveLight ALLEGRETTO laser. J Refract Surg 2008; 24(8): Koller T, Iseli HP, Hafezi F, Mrochen M, Seiler T. Q-factor customized ablation profile for the correction of myopic astigmatism. J Cataract Refract Surg 2006; 32(4):

6 Journal of Isfahan Medical School Original Article Vol 28, No 115, 3 rd week, January 2011 Received: Accepted: Standard PRK Versus Q-value Adjusted Ablation PRK in Refractive Errors Abstract Kobra Nasrollahi MD 1, Hossein Attarzadeh MD 1, Amin Masjedi MD 2, Keyvan Jenab MD 3, Morvarid Kavosh MD 4 Background: This study aimed to evaluate the difference between the effect of standard photorefractive keratectomy (PRK) and Q-value adjusted ablation PRK with Allegretto Eye-Q on the ocular refraction. Methods: In this clinical trial study performed in Parsian clinic of Isfahan, 75 candidates for photorefractive surgery were included. All of these patients underwent standard PRK in one eye and Q-value adjusted ablation PRK in the other eye. The efficacy of therapy was measured by visual acuity, contrast sensitivity, subjective refraction and patients satisfaction, 3 months after the surgery. Finding: The mean score of postoperative visual acuity in standard PRK group and Q-value adjusted group was ± 1.38 and ± 1.22 respectively without correction. The mean postoperative refraction of standard PRK and Q-value adjusted PRK was 0 ± 0.37 and 0.05 ± 0.3 respectively. There was no significant statistical difference in visual acuity, refraction, contrast sensitivity and postoperative satisfaction between the two groups. Conclusion: There is no significant difference between efficacy of standard PRK and Q-value adjusted PRK in optimizing visual acuity, subjective refraction, contrast sensitivity and patient satisfaction. Key words: Ocular refraction, Photorefractive keratectomy, Contrast sensitivity, Patient satisfaction. 1 Associate Professor, Department of Ophthalmology, Feyz Hospital, Isfahan University of Medical Sciences, Isfahan, Iran. 2 Resident, Department of Ophthalmology, Feyz Hospital, Isfahan University of Medical Sciences, Isfahan, Iran. 3 Ophthalmologist, Isfahan University of Medical Sciences, Isfahan, Iran. 4 General Practitioner, Isfahan University of Medical Sciences, Isfahan, Iran. Corresponding Author: Amin Masjedi MD, amin1827@yahoo.co.nz 914

Surgical data reveals that Q-Factor is important for good surgical outcome

Surgical data reveals that Q-Factor is important for good surgical outcome Michael Mrochen, PhD Michael Bueeler, PhD Tobias Koller, MD Theo Seiler, MD, PhD IROC AG Institut für Refraktive und Ophthalmo-Chirurgie