Cell wall deformation and Staphylococcus aureus surface sensing Harapanahalli, Akshay

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1 University of Groningen Cell wall deformation and Staphylococcus aureus surface sensing Harapanahalli, Akshay IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below. Document Version Publisher's PDF, also known as Version of record Publication date: 2015 Link to publication in University of Groningen/UMCG research database Citation for published version (APA): Harapanahalli, A. (2015). Cell wall deformation and Staphylococcus aureus surface sensing [Groningen]: University of Groningen Copyright Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons). Take-down policy If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. Downloaded from the University of Groningen/UMCG research database (Pure): For technical reasons the number of authors shown on this cover page is limited to 10 maximum. Download date:

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3 I feel really lucky and happy to have done my PhD in a diversified group like Biomedical Engineering. In the last 4-5 years of my stay at BME, I also had the opportunity to meet people from different countries, cultures and backgrounds which have broadened my thinking and understanding of the world. Not only did I get to know you all, it was also very interesting to discussed science. Some of them are engineers, chemists and life-science scientists, there was always something interesting to learn from each other and do better as a scientist. Now the time has come for me to say good bye to all of you. Although we will not see eachother on a day-to-day basis, I believe we may cross into eachother someday. During this fascinating journey, I have had help from many people in doing science and arranging administrative things, without which completing my thesis was not possible. Therefore I would like to convay my sincere thanks to you all and share my experiences with each of you. Dear Henk and Henny, You both are like two strong and great pillers of the department overseeing all the PhDs. I have always wondered, how you managed so many projects, wrote grants, assisted PhDs and make successful collaborations across the world. I admire you for this and have learned a lot. Also, I enjoyed the scientific independence to design and execute projects duing my PhD and I appreciate your support in every aspect to bring these projects to a conclusion. Thank you for sharing your expertise and enthusiasm for science and constructive discussions in guiding me in the right direction. Prof. Jan Maarten van Dijl, Prof. Jan Kok and Prof. Yves Durene, thank you for agreeing to be the reading committee for my thesis and suggesting valuable inputs. Bastiaan, thank you for recognizing my research skills and hiring me for the PhD position. Although you moved to Amsterdam after few months I joined, you had already laid the foundation required for my project, and your feedfack during the initial days was very helpful and allowed me to settle down quickly and do the right things required for the project. Prashant, thank you for informing me about the vacancy at BME and forwarding my CV, I will always remember your help which has given me the opportunity to achieve my goal. Also, thank you for interesting discussions during the coffee breaks and for hosting all the BBQ parties during summer. Also, Spoorthi and I really enjoyed the Biryani party during the last New Year s Eve. Thanks you for inviting. 146

4 Jelmer, our discussions regarding two different projects were very interesting. I am also happy that, of those two projects one is accepted and published, in which I am a co-author. Thank you for giving me the opportunity to collaborate. Wya, Ina and Willy, Thank you all for all the help with respect to paper work, financial matters and arranging important things when I joined the department Ed the IT guru of BME, thank you for all the technical support and for arranging a wonderful PC which never gave any problems in the last 5 years. Yun, Juiyi, Deepak and Jessica, thank you all for you collaboration in my PhD. Importantly, I believe each of us have unique expertise which has helped to solve biophysical aspects of Implant-infection relationships in this thesis. Katya and Moijtaba, thank you for giving me the opportunity to contribute to your work and at the same time broaden the understanding of bacterial interactions with its environment. It was great knowing you all and working with. Joop, Willy and Rene, It goes without saying that all you three were very helpful in introducing me to AFM/ DNA lab/ IVIS. Thank you for always being there to help whenever I ran into trouble during the experiments. Joop, thanks for organizing the virtual Word CUP football competition, it was really fun and of course I was more happy when I won. Rene, I appreciate your simplicity and willingness to help all PhD students, thank you for desigining a wonderful cover page for my thesis. Also, discussions during the coffee breaks, lunch breaks or in the corridor were always great. It was good to know you. Present fellows of room number 1265 and former occupants of brain center Deepak, Agnieszka, Otto, Gene, Meyul and Willem, it was great sharing office space with you all, lot of fun and memories. Deepak and Agnieszka, thank you for being such a nice host, we have had many parties and n number of dinners (never had Polish dinner though) at your place. Otto, Gene and Willem, thank you for being a good company at office. Willem and Deepak, special thanks to you both for being my support as paranimphs and for taking responsibility of arranging important things on my defense. Jan, Barbra, Phillip and Jessica, It was fun knowing you guys and thank you for inviting me and Spoorthi to all the birthday parties and house warming parties, it was a nice way to 147

5 catch up outside work. Most of you are not at BME anymore or will finish very soon; I wish you all the success in your careers and life. I also would like to acknowledge all other colleagues Theo, Roel, Danialle, Arina, Stefan, Steven, Vera, Helen, Anna, Song, Joana, Sara, Rebecca, Hilde, Edward, Brian, Brandon, Katya, Rene, Adhi, Das, Marja, Mini, Marianne, Betsy, Chris, Niar, Jelly, Gesinda and Victor, thank you for a pleasant and memorable time at BME. Fortunately, I also have a lot of friends outside BME to balance my work and personal life. My neighbours Rajender and Shilpa, you are almost like a family to us, never needed an appointment to meet up and in numerable dinners, parties and vacations together. We truly enjoyed your company and thank you for being there for us all the time. Shilpa, good luck for your new job and I hope you both will find a balance between work and personal life. Raja babu and Saisri, although you live far away from Groningen (in your village Hoornsemeer) you made it to a point to visit us often for most of the get togethers. Thanks for being there for us and for your kind help to drop us home after late night parties. Apart from general stuff, I found that our discussions were intense and most of the time head on to prove eachother wrong, but I think that s a best way to debate facts. Saisri, when I met you for the first time you were very shy and reserved, but after seeing you at Saritha s party I know you can burn the dance floor, very significant improvement after coming to Europe. Good luck for your new job and I hope you both will find a balance between work and personal life, because travelling is always tyring and time consuming. Shiva and Ananya, Shiva you are the most funny and witty person I have ever met, your presence itself makes me laugh. Thanks for all the fun during our parties and get togethers. Good luck with your PostDoc in Norway. Hope to see you in Netherlands soon. Gopi and Saritha, you both are good friends since long, but I never had a clue that you both were together. I am happy for you both; your couple is unique in our friends circle because you re the first, and may the only doctor couple. My best wishes for your wedding and all the best in life. Kabir Hussain and Julian, we have known each other for not so long but you are very friendly and helping, it was good to know you. Thank you for inviting us to visit your place at 148

6 Stadskanaal, we enjoyed the stay and the tasty food that Julian made. I wish you both and to be born baby all the success and happiness in life. Kiran and Shruthi, Ganesh and Subha, Vikram and Oksana, Eshwar and Mounika Sridhar and Richa, It was very good to meet you all at some point of time in Groningen, thank you all for making my stay in Groningen a memorable one. I am sure we will keep in contact where ever we are and share our experiences in life. Goutam, Pranav, Praneeth, Suresh Vijay, Khayum, Sai Krishna, Arun, Sodhan, Chaitnaya, Shanti, Sunil and Smitha, Tushar, Jasmin, Neha, Pallavi, Amol, Sneha, Abhishek, Veena, Arun Patil and Suchita, It was fun to enjoy Diwali, holi, Bolluwood nights and GISA events with you all. I will always cherish those Groningen moments. All the best in your future endeavors. Meena aunty and Vinod uncle, you both are like guardian angels, always ready to help and take care like a family, very kind and down to earth. I admire you both for your qualities and values. Thank you for all the help Uncle and Aunty. Vinesh, Vinay and Nawina, it was good to know you guys, enjoyed the movie nights and dinners we had to gether, success to you all in your endeavors. Bhaskar Reddy uncle, thank you for helping me during difficult times, it is because of you I was able to pursue my Masters in The Netherlands. I wish you and you family all the success and happiness. Niveditha (Sister) and Kalyan bava (Brother-in-law), thank you so much for your immense support and advice at the end of my PhD days. It is always fun to catch up with you guys, we should meet more frequently. I will miss you both on my defense and party. Love you both. Sahitya / Sali, you r my darling, fun loving and a lovely girl. Very happy to have you as my Sali, but you should keep our secrets a secret and not tell them to your sister. Good luck with your Masters in Belgium. Janardhan Mamayya (Father-in-law) and Bramara attamma (Mother-in-law), your support and encouragement has always helped me during my PhD. Thank you for your love and care. 149

7 Amma (Mother) and Nana (Father), I do not know how to say thank you for all the things you have done for me. It is because of your teachings and values imbibed in me; I have reached this happy day in my life. Nana, thank you for all your efforts and hardships to provide me with good education. This is the biggest asset that you can ever give me. I will miss you on my defense. I wish you all the happiness in life. Last but not the least; Dear wife Spoorthi, thank you for being my greatest support during good and bad times; your words always filled confidence in me. I am very happy to have you in my life. 150