DNA Haplogroups Report

Transcription

1 DNA Haplogroups Report for Matthew Mayberry Generated and printed on Sep , 01:59 pm X This is a mtdna Haplogroup Report This is a mtdna Subclade Report Search criteria used in this report: HVR-1 markers This report contains the following sections: Section 1. Distribution Section 2. Description Section 3. mtdna Phylogenetic Tree Section 4. Further Studies Powered by Genebase Systems. 1 of 10 9/25/11 5:02 PM

2 DNA Haplogroups Report generated by Genebase Systems and printed on Sep , 01:59 pm mtdna Haplogroup of Matthew Mayberry Based on the SNP marker pattern found in Matthew Mayberry's HVR-1 markers, Matthew Mayberry's mtdna Haplogroup can be predicted. The top five mtdna haplogroup predictions are as follows: (1) B, (2) H, (3) HV, (4) R0, (5) R. Section 1: Distribution of Matthew Mayberry's Haplogroup Timeline of mtdna Haplogroup B Matthew Mayberry's predicted maternal haplogroup, B, arose from 10 key detectable genetic events over the past 150,000 years. This timeline illustrates how Haplogroup B arose and shows the genetic changes that occurred over time, resulting in its present day form. You can confirm Matthew Mayberry's membership in haplogroup B through Backbone SNP testing to see if Matthew Mayberry is positive for the defining SNPs for haplogroup B. L(origin) (4312 (??)) L1-6 L2-6 L2,3,4,6 L3,4,6 (3594 (??)) L3,L4 L3 (10873 (??)) N (12705 (??)) R (11719 (??)) R11,B B Migration Map of mtdna Haplogroup B The location where each of the key genetic markers is found in the world can be plotted on a map to reconstruct the ancient migration patterns of Matthew Mayberry's ancestors. This migration map indicates the migration pattern of Matthew's maternal ancestors based on Matthew's predicted mtdna haplogroup. * Please note that this is Matthew's predicted haplogroup based on mtdna markers. Matthew's mtdna haplogroup can be confirmed through mtdna SNP Backbone Testing which will confirm the presence or absence of Haplogroup specific SNP markers in Matthew's mtdna. Order the mtdna SNP Backbone Test to confirm Matthew's mtdna haplogroup. How is Matthew's mtdna Haplogroup predicted? Map data 2011 Geocentre Consulting, MapLink, Tele Atlas - Matthew's mtdna results are compared to people in the database who have already confirmed their mtdna Haplogroup through SNP testing. The prediction strength indicates how closely Matthew's mtdna profile (haplotype) matches the profiles of people with confirmed mtdna Haplogroups. The higher the prediction strength, the more closely Matthew's haplotype matches the haplotype of other individuals with a known Haplogroup. Please note that STR markers can only be used to generate a mtdna Haplogroup prediction. Matthew's mtdna Haplogroup can be confirmed through mtdna SNP Backbone testing. 2 of 10 9/25/11 5:02 PM

3 About the Haplogroup Migration Map Researchers are able to plot the migration path of our ancient maternal ancestors by examining the pattern of mtdna SNP markers found in "indigenous" populations from around the world. By determining the location where key mtdna SNP markers first arose and the approximate time that each mtdna SNP marker arose, researchers have been able to successfully plot the ancient migration patterns of man based on the pattern of SNPs found in their mtdna. SNP markers are often referred to as "time and date stamps" because each marker can be traced back to a particular time and place in history. By testing the SNP markers in Matthew's mtdna, you can determine Matthew's unique pattern of SNP markers. Matthew's mtdna SNP markers allow you to confirm Matthew's mtdna Haplogroup and view the migration patterns of Matthew's own maternal ancestors. Understanding the Haplogroup Migration Map The mtdna Haplogroup migration map shows the place of origin of Matthew's maternal ancestors and the arrows in the map indicate the subsequent migration patterns of ensuing generations based on the unique pattern of SNPs found in Matthew's mtdna. Click here to download a copy of the mtdna phylogenetic tree which shows in detail how each SNP marker in the mtdna is associated with various haplogroups. Get More Information To refine or confirm the mtdna haplogroup of Matthew Mayberry, you may consider ordering the mtdna HVR-2 Upgrade Test and mtdna Backbone SNP Test. Click here to find out more about the mtdna Full Sequencing Test. Recommended Reading The more you understand about the role of mtdna in maternal ancestry, the more you will get out of your genetic genealogy experience. For those who are interested in understanding the science behind the technology, we recommend reading our lesson series entitled "The role of mtdna in Ancestry" for helpful core background information. Click here to explore the phylogenetic tree of human mtdna and see how Matthew Mayberry's predicted mtdna haplogroup is connected to other major haplogroups. Click here to read more about Matthew Mayberry's predicted mtdna haplogroup. 3 of 10 9/25/11 5:02 PM

4 Section 2: Description of Matthew Mayberry's Haplogroup Haplogroup B Time: Emerged approx 60,000 years ago Place: Originated in Asia Facts: The woman who founded Haplogroup B lived approximately 50,000 years ago in Asia. Descendents of the Haplogroup B migrated throughout Asia and into the Americas approximately 20,000 years ago. Haplogroup B is one of five haplogroups found in indigenous peoples of the Americas (others are A, C, D, and X). Native American Ancestry Today, descendents of Haplogroup B can be found throughout Asia, including China, Korea and Japan and Southeast Asia. It is also found in a significant proportion of Native Americans. Unlike other haplogroups that were migrated into the New World, haplogroup B is the only one that is not found in today's North Siberian populations. Facts The woman who founded the Haplogroup B line is the direct female descendent of a woman belonging to the Haplogroup R line. Haplogroup R is Near/Middle Eastern and Caucasus in origin. 4 of 10 9/25/11 5:02 PM

5 Section 3: Matthew Mayberry's Placement in the mtdna Phylogenetic Tree Location of mtdna Haplogroup B in Phylogenetic Tree DNA studies have shown that all people living today descended from common ancestors who lived in Africa over 100,000 years ago. This genetic association can be plotted into a worldwide "family tree of mankind" called a "phylogenetic" tree. The phylogenetic tree below is based on the Human mtdna and shows how all human maternal lineages (mtdna haplogroups) are connected to each other. Scroll down the tree to see where Matthew Mayberry's predicted mtdna haplogroup, B, is located. SNP marker tested by Genebase = 1048, 4312, 6185, 11914, L0 3516A, 5442, 9042, 9347, 10589, 10664, 10915, 12720, 13276, L0a,b,f,k 189, 4586, 9818, , 6815, 8113A, 8152, 8251, 12121, 15466, 15930, 15941, L , 2758, 2885, 7146, 8468 L1 3666, 7055, 7389, 13789, 14178, L1b 185T, 357, 709, 1738, 2352, 3308, 3693, 5036, 5046, 5655, 6548, 6827, 6989, 7867, 8248, 12519, 13880A, 14203, 14769, 15115, 16264, L1b L1c 151, 186A, 189C, 316, 2395d, 5951, 6071, 8027, 9072, 10586, 12810, 13485, 14000A, 14911, 16294, L , 247, d, 825A, 8655, 10688, 10810, 13105, 16129, 16187, L2,3,4,6 4104, 7521 L2 146, 150, 152, 2416, 8206, 9221, 10115, L2a-d 195, L2e 479, 719, 1211, 3537, 4562, 5069T, 6014, 8383, 9377, 9971, 11935, 12189, 13708, 14299, 15697, 15734, 15889, 16111A, 16145, 16184, 16239, 16292, 16355, 16399, L3,4,6 182, 3594, 7256, 13650, L3,L4 769, 1018, L3 8701, 9540, 10398, 10873, L3a 152, d, 12816, L3b-d,j d, L3b 3450, 5773, 6221, 9449, 10086, 13914A, 15311, 15824, 15944d, 16124, 16278, L3b L3b2 3420, 16183C, L3c,d,j 152 L3c 195, 498.1C, 678, 3582, 4491, 5393, 7394, 9337, 9682, 12373, 14221, 14371, 14560, 14587, 16111, L3d 5147, 7424, 8618, 13886, 14284, L3d L3j 5821, 6182, 6722, 8676, 9365, 9731A, 12280, 12534, 14260, 15314, 15479, L3e,i,k,x 150, L3e 2352, L3e1 189, 200, 6221, 6587, 14152, 15670, 15942, L3e2 195, 14905, L3e3-5 L3i 7645 L3k 235, 494, 3918, 6620G, 9467, 13135, 13992, L3x 3483, C, 6401, 8311, 8817, 13708, L3f 3396, 4218, 15514, 15944d, L3h 7861, 9575 M 489, 10400, 14783, D 4883, 5178A, D4 3010, 8414, D5, of 10 9/25/11 5:02 PM

6 M1 195, 6446, 6680, 12403, 12905C, 14110, 16129, 16189, 16249, M2 447G, 1780, 8502, 11083, 15670, 16274, M3 482, M4" M5 1888, M6 461, 3537, 5082, 5301, 5558, 9329, 10640, 13966, 14128, 16231, M7 6455, 9824 M8 4715, 7196A, 8584, 15487T, CZ 249d C 3552A, 9545, 11914, 13263, 14318, C d, C A, 6026, 11969, C C, C6 1888, C7 5821, 6338, 7853 Z 152, 6752, 9090, 15784, 16185, Z1 151, 10325, 15261, 16129, Z2 3145, 8188, 14668, Z Z4 5492, 15475, 15944d, 16189, M8a 6179, 8684, 14470, M9 4491, E 3027, 3705, 7598, 13626, E1 4248, 10834, 13254, E2 195, 8440, 9080, 15178, M9a-d 153, 3394 M10, M11 146, 215, 318, 326, 1095, 6531, 7642, 8108, 9950, 11969, M12,G G 709, 4833, 5108, G1 8200, 15323, G2 5601, G G A, 194, 4541, 5051, 5460, 6216, 7521, 7660, 9670, 11383, 15940, 16114A M , 5580, 12030, 12372, 14727, 15010, 16172, 16234, M13 152, 3644, 5773, 6023, 6253, 6620, 10411, 10790, 15924, 16145, M14 234, 4216, 6962 M21 709, M22, M , 9201, M28 152, 195, 1719, 6281, 6374, 10245, 15067, 16148, 16362, M29,Q 13500, M31, A M M34 569, 3010, 6794, 11101, 15865, M M36 239, 7271, M T, 65.1T, 66T, 1811, 8679, M , 15721, 15954, M41 375, 870, 6297, 12398, 12469, 13656, 15601, 16327, M44 146, 930, 961, CC, 8179, C, of 10 9/25/11 5:02 PM

7 M46 146, 152, 1393, 3588, 4394, 6032, 6253, 7828, 8886, 9115, 10130, 11008, 11151, 13434, 16256, 16278, 16300, 16343T, M47, C M48 199, 6366, 15900, 16225, 16234, M , 11263, 12346, 14384, 15511, 15647, 16153, N 12705, A 152, 235, 663, 1736, 4248, 4824, 8794, 16290, A3 2857, 8962, 9711 A A5 8563, A7 146, 8413, 10172, 15379, 16051, 16129, A8 64 N1, N , N1a,c,d,e,I 204, N1a,d,e,I 199 N1c 73, 75, 189, 195, 207, 210, 8222, 11025, 11437, 13637, 16201, N1b 152, 1598, 1703, 2639, 3921A, 4960, 5471, 8251, 8472, 8836, 12822, 16145, 16176G, N5 5063, 7076, 9545, 11626, 13434, 16111, N2 709, 189, 5046, 11674, N2a 152, 199, 739, 1633, 7581, 10841, 11722, 12192, 15106, 16153, W 195, 204, 207, 1243, 3505, 5460, 8251, 8994, 11947, 15884C, W W3 1406, 13263, W4 143, 192, 194, 196 W5 6528, N N9a 150, 5231, 12358, 12372, 16257A, N9b 5147, 10607, 11016, 13183, 14893, Y 8392, 10398, 14178, 14693, Y1 3834, Y2 482, 5147, 6941, 7859, 14914, 15244, R 73, P P1 212, 6077, 10118, 16176, 16266, , 3882, 4122, 8859, P3 127, 128, CCC, 3645, 14338, 15748, 15937T P4 1719, 5460, P6 6719, 16311, R HV 2706, 7028 H 1438 H* H H H2a 750 H2a1 951, H2a2 263, 8860, H2a2a CRS H2a2b H2a , H2a of 10 9/25/11 5:02 PM

8 H2a , 16291, 1842, 4592 (16291 is variable in subclade H2a5.) H2b 152, 8598, H H4 3992, 5004, 9123 H5, H6, H H9 152, 3591, 4310, 13020, H A H11, H H , 10217, H15 55, 57, 6253 H H , 6296 H H H , 16328A H H , H H H , 16093, H30 195, 8638, HV0 72, HV0a HV0b,c 195 HV1 8014T, 15218, HV2 7193, 9336, HV HV HV , R0a 64, 2442, 3847, 13188, 16126, R1 295A, 1391, 3360, 4917, 5586, 5823, 6557, 6671, 7547, 8388, 8887, 10658, 10825, 13948, 14632, 15721, R2,JT 4216 JT 11251, 15452A, J 295, 489, 10398, 12612, 13708, J1 462, 3010 J2 150, 152, 7476, T 709, 1888, 4917, 8697, 10463, 13368, 14905, 15607, 15928, T A, 16163, T , 14233, (16296 is variable in subclade T2.) T R2 152, 7657, 8473, 9932, 10685, 12654, 13500, 14305, R5 8594, 10754, 14544, 16304, R6, R8 2755, 3384, 7759, 9449, R9,21, R9 3970, 13928C F 249d, 6392, F1 6962, 10609, 12406, of 10 9/25/11 5:02 PM

9 F2 1005, 1824, 7828, 10535, 10586, 12338, F3 3434, 5585, 5913, 5978, 10320, 11065, F4 5263, 12630, R9b 1541, 12714, 16309, R , 12234, 12361, 12510, 16168, R , R11,B B «Matthew Mayberry (predicted haplogroup) d B B5 709, 8584, 9950, 10398, B6 150, 5894C, 9452, 11914, 12950, 13928C, 14305, 16093, R11 185, 189, 709, 8277, 10031, 10398, 11061, 12950, 13681, R , 16290, R R U 11467, 12308, U1 285, 12879, 13104, 14070, 15148, 15954C, U2,3,4,7,8, U U3 150, 14139, 15454, U4,9 499, 5999 U7 152, 980, 5360, 10142, 16318T U U8a 282, 6392, 6455, 7055, 9365, U8b,K 9055, K 16224, 3480, 10550, 11299, 14798, K1 1189, K2 146, 9716 U8b 12771, 6546, 6599, 16189, U5 3197, 9477, 13617, U6 3348, S 8404 X 153, 6221, 6371, 13966, 14470, 16189, X1 146 X2 195, 1719 L L6 146, 152, 185C, 709, 770, 961, 1461, 4964, 5267, 6002, 6284, 9332, 10978, 11116, 11743, 12771, 13710, 14791, 14959, 15244, 15289, 15499, 16048, L C, 3423, 7972, 12432, 12950, 16148, Reference: van Oven M, Kayser M Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation. Hum Mutat 30(2):E386- E394.doi: /humu Our mtdna, which is passed down from a mother to her children shows that all people living today shared a common female ancestor who lived in Africa over 100,000 years ago. She is often termed the "Mitochondrial Eve". The mtdna phylogenetic tree has approximately 26 main branches "mtdna haplogroups" classified by the letters "A to Z". Each mtdna haplogroup has many further sub-branches (subclades), classified by numbers and letters, i.e. L1a1, L1a2, L1b, etc. All people living today have descended from one of the main branches of the human mtdna phylogenetic tree. Find Matthew's haplogroup on the tree and see how Matthew is connected to all people living today on Matthew's maternal line. 9 of 10 9/25/11 5:02 PM

10 Section 4: Further Studies for Matthew Mayberry's Haplogroup Genebase Systems. All Rights Reserved. 10 of 10 9/25/11 5:02 PM