VALUE IN HEALTH 18 (2015) A308-A318

Transcription

1 A308 DISCLOSURE INFORMATION Research Presentations Financial Disclosure Statements The International Society for Pharmacoeconomics and Outcomes Research asked all abstract contributors to disclose fi nancial support for their research. The following fi nancial support was declared: CN1 CN2 CN3 CN4 CP1 CP2 CP3 CP4 CS1 CS2 CS3 CS4 CV1 CV2 CV3 CV4 DB1 DB2 DB3 DB4 HE1 HE2 HE3 HE4 HM1 HM2 HM3 HM4 HT1 HT2 HT3 HT4 MA1 MA2 MA3 MA4 MD1 MD2 MD3 MD4 MO1 MO2 MO3 MO4 PCN1 PCN10 PCN100 PCN101 PCN102 PCN103 PCN104 PCN105 PCN106 PCN107 PCN108 PCN109 PCN11 PCN110 PCN111 PCN112 PCN113 PCN114 PCN115 PCN116 PCN117 PCN118 Genentech, South San Francisco, CA, Celgene, Summit, NJ, RTI-Health Solutions, Research Triangle Park, NC, Genzyme Europe, Naarden, NA, Netherlands; BioMarin Europe, London, NA, UK U.S. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD, British Heart Foundation, London, NA, UK Bristol-Myers Squibb, New York, NY, CADTH, Ottawa, ON, Canada National Cancer Institute at the National Institutes of Health, Bethesda, MD, ; Agency for Healthcare Research and Quality, Rockville, MD, ; Breast Cancer Research Foundation, New York, NY, ; Foundation for Barnes Jewish Hospital, St. Louis, MO, The Israel National Institute for Health Policy Research, Tel-Aviv, NA, Israel Abbott Vascular, Santa Clara, CA, Amgen,Inc., Thousand Oaks, CA, Bayer Healthcare Pharmaceuticals, Whippany, NJ, Sanofi, Bridgewater, NJ, ; Regeneron, Tarrytown, NY, AstraZeneca, Wilmington, DE, AHRQ, DC, NA, National Institute of Aging, Bethesda, MD, NIH Common Fund, Bethesda, MD, Agency for Healthcare Research and Quality, Rockville, MD, Walgreen Co., Deerfi eld, IL, Ferrer, Barcelona, NA, Spain TEVA Pharmaceuticals, Frazer, PA, Piramal Life Sciences, Laval, QC, Canada Vapotherm Inc.., Exeter, NH, Bayer HealthCare, Leverkusen, NA, Germany Merck & Co., Inc., Rahway, NJ, Bayer Healthcare Pharmaceuticals, Whippany, NJ, Janssen Scientifi c Affairs, LLC, Horsham, PA, Productos Roche, Bogota, NA, Colombia Celgene Corporation, Plainfi eld, NJ, Sunesis Pharmaceuticals, South San Francisco, CA, Onyx Pharmaceuticals,Inc.,, an Amgen subsidiary, San Francisco, CA, AMGEN, Uxbridge, NA, UK Eli Lilly and Company, Indianapolis, IN, Astellas Scientifi c and Medical Affairs, Northbrook, IL, ; Medivation, Inc., San Francisco, CA, Lilly Deutschland GmbH, Bad Homburg, NA, Germany Novartis Pharmaceuticals, East Hanover, NJ, PCN119 PCN120 PCN121 PCN122 PCN123 PCN124 PCN125 PCN126 PCN127 PCN128 PCN129 PCN13 PCN130 PCN131 PCN132 PCN134 PCN135 PCN136 PCN137 PCN138 PCN139 PCN14 PCN140 PCN141 PCN142 PCN143 PCN144 PCN145 PCN146 PCN147 PCN148 PCN149 PCN150 PCN152 PCN153 PCN154 PCN155 PCN156 PCN157 PCN158 PCN159 PCN16 PCN160 PCN161 PCN164 PCN165 PCN166 PCN167 PCN168 PCN169 PCN17 PCN171 PCN172 PCN173 PCN174 PCN175 PCN176 Merck & Co, Whitehouse Station, NJ, ; Millennium Pharmaceuticals Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, Cambridge, MA, ; Johnson and Johnson Pharmacetical Research and Development, Raritan, NJ, ; Boehringer Ingelheim International GmbH, Ingelheim am Rhein, NA, Germany; Sanovi-Aventis R&D, Chilly Mazarin, NA, France; Cephalon, Inc.., Frazer, PA, ; Novartis, East Hanover, NJ, Pfi zer, New York, NY, Pfi zer, New York, NY, Novartis Pharmaceuticals UK Limited, Surrey, NA, UK Eisai Inc., Woodcliff Lake, NJ, Astellas Pharma, Inc., Northbrook, IL, Astellas Medical and Scientifi c Affairs, Inc.., Northbrook, IL, ; Medivation, Inc., San Francisco, CA, Novartis Pharmaceuticals UK Limited, Surrey, NA, UK Astellas Medical and Scientifi c Affairs, Inc.., Northbrook, IL, ; Medivation, Inc., San Francisco, CA, United States Centers for Disease Control and Prevention, Atlanta, GA, Novartis Pharmaceutical Corporation, East Hanover, NJ, Decision Resources Group, Burlington, MA, Celldex Therapeutics, Hampton, NJ, IMS Brogan, Ottawa, ON, Canada Millennium Pharmaceuticals, Cambridge, MA, Johnson & Johnson, Cincinnati, OH, Decision Resources Group, Burlington, MA, Decision Resources Group, London, NA, UK USC-ASPIRE, Columbia, SC, NIH Offi ce on Women's Health, Bethesda, MD, ; National Cancer Institute, Bethesda, MD, GlaxoSmithKline, RTP, NC, HealthCore, Inc., Wilmington, DE, Agency for Healthcare Research and Quality's (AHRQ), Rockville, MD, ; National Institute of General Medical Sciences, Bethesda, MD, National Institute of General Medicine Sciences, Bethesda, MD, ; Agency for Healthcare Research and Quality (AHRQ), Rockville, MD, National Institutes of Health, Bethesda, MD, PA Department of Health, Harrisburg, PA, Quintiles, Durham, NC, National Science Council, Tainan, NA, Taiwan; Ministry of Health and Welfare, Taipei, NA, Taiwan; National Cheng Kung University, Tainan, NA, Taiwan National Cancer Institute, NIH, Bethesda, MD, PRMA Consulting, Fleet, NA, UK Copyright 2015, International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc.

2 A309 PCN177 PCN179 PCN18 PCN180 PCN181 PCN182 PCN183 PCN184 PCN186 PCN187 PCN19 PCN2 PCN20 PCN21 PCN22 PCN23 PCN24 PCN25 PCN26 PCN27 PCN28 PCN3 PCN30 PCN31 PCN32 PCN33 PCN34 PCN35 PCN36 PCN37 PCN38 PCN39 PCN4 PCN40 PCN41 PCN42 PCN43 PCN44 PCN45 PCN46 PCN47 PCN48 PCN49 PCN5 PCN50 PCN51 PCN52 PCN53 PCN54 PCN55 PCN56 PCN57 PCN58 PCN59 PCN6 PCN60 PCN61 PCN62 PCN63 PCN64 PCN65 PCN66 PCN67 PCN68 PCN69 PCN7 PCN70 PCN71 PCN72 PCN73 PCN74 PCN75 PCN77 PCN78 PCN79 AstraZeneca, Cheshire, NA, UK; Quintiles Consulting, Hoofddorp, NA, UK Quintiles Consulting, Hoofddorp, NA, UK; AstraZeneca, Cheshire, NA, UK Ministry of Education, Science and Technological Development, Belgrade, NA, Serbia and Montenegro Amaris, Toronto, ON, Canada NIH, Bethesda, MD, Millennium Pharmaceuticals, Cambridge, MA, Amgen Inc., Thousand Oaks, CA, Tai-Shang Resources International System, Taipei, NA, Taiwan; Mundipharma Pte Ltd., Taipei, NA, Taiwan Eisai, Woodcliff Lakes, NJ, Bayer Healthcare, Whippany, NJ, Agency of Healthcare Research and Quality, Rockville, MD, ; National Institute Of General Medical Sciences, Bethesda, MD, Astellas Medical and Scientifi c Affairs, Inc., Northbrook, IL, ; Medivation Inc., San Francisco, CA, Bristol Myers Squibb, Princeton, NJ, Eisai, Inc., Woodcliff Lake, NJ, Johnson and Johnson Medical Companies, Markham, ON, Canada Astellas Medical Scientifi c Affairs, Inc., Northbrook, IL, ; Medivation, Inc., San Francisco, CA, Lake Champlain Cancer Research Organization, Essex JCT., VT, ; National Cancer Institute, Bethesda, MD, Ministry of Health, Buenos Aires, NA, Argentina Pfi zer, Inc., New York, NY, Braintree Laboratories, Inc., Braintree, MA, Bayer HealthCare Pharmaceuticals, Inc., Whippany, NJ, Bristol-Myers Squibb, Lawrenceville, NJ, Roche, São Paulo, NA, Brazil Genome Canada, Ottawa, ON, Canada Eisai, Inc., Woodcliff Lake, NJ, Bayer HealthCare, Whippany, NJ, Bristol-Myers Squibb, Princeton, NJ, Teva Pharmaceutical, Philadelphia, PA, Geisinger Health System, Danville, PA, ; Cernostics Inc., Pittsburgh, PA, Johnson & Johnson, Cincinnati, OH, Johnson & Johnson, Cincinnati, OH, Bayer Healthcare Pharmaceuticals, Whippany, NJ, Bayer Healthcare Pharmaceuticals, Whippany, NJ, Bayer Healthcare Pharmaceuticals, Whippany, NJ, Bristol-Myers Squibb, Santiago, NA, Chile F. Hoffmann-La Roche, Basel, NA, Switzerland Eisai, Woodcliff Lake, NJ, Teva Pharmaceutical, Frazer, PA, Bayer HealthCare, Whippany, NJ, Prostate Cancer Canada, Toronto, ON, Canada Eisai Inc., Woodcliff Lake, NJ, Bayer HealthCare Pharmaceuticals, Inc., Whippany, NJ, PCN8 PCN80 PCN81 PCN82 PCN84 PCN85 PCN86 PCN87 PCN88 PCN89 PCN9 PCN90 PCN92 PCN93 PCN94 PCN95 PCN96 PCN97 PCN98 PCV1 PCV10 PCV100 PCV101 PCV102 PCV103 PCV104 PCV105 PCV106 PCV107 PCV108 PCV109 PCV11 PCV110 PCV112 PCV113 PCV114 PCV115 PCV116 PCV117 PCV118 PCV119 PCV12 PCV120 PCV121 PCV122 PCV123 PCV124 PCV125 PCV126 PCV127 PCV128 PCV129 PCV130 PCV131 PCV14 PCV15 PCV16 PCV17 PCV18 PCV19 PCV2 PCV20 PCV21 PCV22 PCV23 PCV24 PCV25 PCV26 PCV27 PCV28 PCV29 PCV3 PCV30 PCV31 Bayer Turk Kimya San. Ltd. Sti, Istanbul, NA, Turkey Boehringer Ingelheim, Mexico City, NA, Mexico AmgenInc.., Thousand Oaks, CA, National Cancer Institute, Bethesda, MD, Metamark Genetics, Cambridge, MA, Bristol-Myers Squibb, Lima, NA, Peru National Institute of Health, Bethesda, MD, ; National Cancer Institute, Bethesda, MD, ; Janice Davis Gordon fellowship, Houston, TX, Audifarma S.A., Pereira, NA, Colombia; Universidad Tecnológica de Pereira, Pereira, NA, Colombia CIHI, Ottawa, ON, Canada UNC Eshelman School of Pharmacy, Chapel Hill, NC, Penn Pfi zer Alliance, Philaldephia, PA, The Medicines Company, Parsippany, NJ, Amgen, Thousand Oaks, CA, Amgen, Thousand Oaks, CA, Eli Lilly and Company, Indianapolis, IN, Amgen, Thousand Oaks, CA, Alberta Provincial Stroke Strategy, Alberta Health Services, Edmonton, AB, Canada; Heart and Stroke Foundation Canada, Ottawa, ON, Canada Heart and Stroke Foundation Canada, Ottawa, ON, Canada; Alberta Provincial Stroke Strategy, Alberta Health Services, Edmonton, AB, Canada National Cancer Institute at the National Institutes of Health, Bethesda, MD, ; Agency for Healthcare Research and Quality, Rockville, MD, ; Breast Cancer Research Foundation, New York, NY, ; Foundation for Barnes Jewish Hospital, St. Louis, MO, Ministry of Health, Buenos Aires, NA, Argentina Sanofi, Bridgewater, NJ, ; Regeneron, Tarrytown, NY, The Medicines Company, Parsippany, NJ, Bristol- Myers Squibb, Princeton, NJ, ; Pfi zer Inc., New York, NY, Pfi zer Inc., New York, NY, ; BMS, Princeton, NJ, Medac-Chemotera, Almaty, NA, Kazakhstan Invaluesys Research, Burgdorf, NA, Germany Baxter Healthcare, Deerfi eld, IL, Food and Drug Administration, Silver Spring, MD, Amerihealth Caritas, Philadelphia, PA, NIPER, MOHALI, NA, India

3 A310 PCV32 PCV33 PCV34 PCV35 PCV36 PCV37 PCV38 PCV39 PCV4 PCV40 PCV41 PCV42 PCV43 PCV44 PCV45 PCV46 PCV47 PCV48 PCV49 PCV5 PCV50 PCV51 PCV52 PCV53 PCV54 PCV55 PCV56 PCV57 PCV58 PCV59 PCV6 PCV60 PCV62 PCV63 PCV64 PCV65 PCV66 PCV67 PCV68 PCV69 PCV7 PCV70 PCV72 PCV73 PCV74 PCV76 PCV77 PCV78 PCV79 PCV8 PCV80 PCV81 PCV82 PCV83 PCV84 PCV85 PCV86 PCV87 PCV88 PCV89 PCV9 PCV90 PCV91 PCV92 PCV93 PCV94 PCV95 PCV96 PCV97 PCV98 PCV99 PDB1 PDB10 PDB100 PDB101 PDB102 PDB11 PDB12 PDB13 PDB14 PDB15 PDB16 PDB17 Relypsa, Inc., Redwood City, CA, Pfi zer Japan Inc., Tokyo, NA, Japan The Medicines Company, Parsippany, NJ, Grifols, Inc., Research Triangle Park, NC, Instituto de Salud Publica, Santiago, NA, Chile Bristol-Myers Squibb, Plainsboro, NJ, ; Pfi zer, New York, NY, Pfi zer Inc., New York, NY, ; Bristol-Myers Squibb, New York, NY, Genentech Inc., South San Francisco, CA, Amgen, Inc., Thousand Oaks, CA, Amgen, Thousand Oaks, CA, Biogen Idec, Inc., Cambridge, MA, Novartis, Frimley, NA, UK Amgen Inc., Thousand Oaks, CA, Ethicon, Inc., Somerville, NJ, Invaluesys Research, Burgdorf, NA, Germany Medac-Chemotera, Almaty, NA, Kazakhstan Boehringer Ingelheim, Mexico City, NA, Mexico Boehringer Ingelheim, Bogota, NA, Colombia Boehringer Ingelheim, Mexico City, NA, Mexico Sanofi, China, Shanghai, NA, China Bayer Turk Kimya San. Ltd. Sti., Istanbul, NA, Turkey Medac-Chemotera, Almaty, NA, Kazakhstan Pfi zer Central America and Caribbean, San José, NA, Costa Rica Boehringer Ingelheim GmbH, Ingelheim am Rhein, NA, Germany Avivia, Mexico City, NA, Mexico Bristol-Myers Squibb, Lima, NA, Peru CADTH, Ottawa, ON, Canada Edwards Lifesciences, Inc., Irvine, CA, Chair on adherence to treatments, Quebec, QC, Canada Vietnam - Netherlands Project, Ha Noi, NA, Vietnam BMS, Princeton, NJ, ; Pfi zer, New York, NY, Johnson & Johnson Medical Brazil, Sao Paulo, NA, Brazil Bristol-Myers Squibb, Plainsboro, NJ, ; Pfi zer, New York, NY, Institute for Pharmaceutical Outcomes and Policy, Lexington, KY, AstraZeneca, Fort Washington, PA, Sanofi US, Inc., Bridgewater, NJ, Novo Nordisk, Inc., Plainsboro, NJ, Janssen Pharmaceutica NV, Beerse, NA, Belgium Janssen Scientifi c Affairs, Raritan, NJ, Boehringer Ingelheim, Ridgefi eld, CT, Janssen Scientifi c Affairs, LLC, Raritan, NJ, Janssen-Cilag, Dublin, NA, Ireland PDB18 PDB19 PDB2 PDB20 PDB21 PDB22 PDB23 PDB24 PDB25 PDB26 PDB27 PDB28 PDB29 PDB3 PDB30 PDB31 PDB32 PDB34 PDB35 PDB36 PDB37 PDB39 PDB4 PDB40 PDB41 PDB42 PDB43 PDB44 PDB45 PDB46 PDB47 PDB48 PDB49 PDB5 PDB50 PDB51 PDB52 PDB53 PDB54 PDB55 PDB56 PDB57 PDB58 PDB59 PDB6 PDB60 PDB61 PDB62 PDB63 PDB64 PDB65 PDB66 PDB67 PDB68 PDB69 PDB7 PDB70 PDB71 PDB72 PDB73 PDB74 PDB75 PDB76 PDB77 PDB78 PDB79 PDB8 PDB80 PDB81 PDB82 PDB83 PDB84 PDB85 PDB86 PDB87 PDB88 PDB89 PDB9 PDB90 PDB91 PDB92 PDB93 PDB94 PDB95 PDB96 PDB97 Brazilian Ministry of Health/CNPq, Brasilia, NA, Brazil Merck Serono, S, NA, Brazil BMS, Wallingford, CT, Janssen UK, High Wycombe, NA, UK AstraZeneca Pharmaceuticals, Fort Washington, PA, Janssen Scientifi c Affairs, LLC, Raritan, NJ, Boehringer Ingelheim GmbH, Ingelheim, NA, Germany AstraZeneca Pharmaceuticals LP, Wilmington, DE, AstraZeneca, Fort Washington, PA, Eli Lilly and Company, Indianapolis, IN, AstraZeneca, Fort Washington, PA, Pfi zer, Inc., Groton, CT, Genentech, Inc., South San Francisco, CA, Ethicon, Cincinnati, OH, Omada health, San Francisco, CA, Novartis, Basel, NA, Switzerland CNPq, Brasilia, NA, Brazil Janssen Inc., Toronto, ON, Canada Independence Blue Cross, Philadelphia, PA, Janssen Pharmaceutica NV, Beerse, NA, Belgium Boehringer Ingelheim, Mexico City, NA, Mexico Janssen Inc., Toronto, ON, Canada Janssen Pharmaceutica NV, Beerse, NA, Belgium Novo Nordisk, Copenhaguen, NA, Denmark Janssen Global Services, LLC, Raritan, NJ, Janssen Inc., Toronto, ON, Canada Merck Sharp & Dohme, Mexico, NA, Mexico Novo Nordisk Colombia, Bogota, NA, Colombia Boehringer Ingelheim, Ridgefi eld, CT, AstraZeneca, Fort Washington, PA, Genentech, Inc., South San Francisco, CA, Independence Blue Cross, Philadelphia, PA, Kantar Health, New York, NY, Novo Nordisk, Copenhagen, NA, Denmark Genentech, Inc., South San Francisco, CA, PHT Corporation, Boston, MA, Novo Nordisk, Madrid, NA, Spain Janssen Global Services, LLC, Raritan, NJ, University of Washington, the Department of Anesthesiology and Pain Medicine, Seattle, WA, Janssen Scientifi c Affairs, LLC, Raritan, NJ, Eisai, Inc., Woodcliff Lake, NJ, Janssen Global Services, LLC, Raritan, NJ, Novo Nordisk A/S, Bagsvaerd, NA, Denmark Novo Nordisk, Plainsboro, NJ, Janssen Global Services, LLC, Raritan, NJ, Pfi zer Inc., New York, NY, Pfi zer Inc., New York, NY,

4 A311 PDB98 PDB99 PGI1 PGI10 PGI11 PGI12 PGI13 PGI14 PGI15 PGI16 PGI17 PGI18 PGI19 PGI2 PGI20 PGI21 PGI22 PGI23 PGI24 PGI25 PGI26 PGI27 PGI28 PGI29 PGI3 PGI30 PGI31 PGI32 PGI33 PGI34 PGI35 PGI36 PGI4 PGI5 PGI6 PGI7 PGI8 PGI9 PHP1 PHP10 PHP100 PHP101 PHP102 PHP103 PHP104 PHP105 PHP106 PHP107 PHP108 PHP109 PHP110 PHP111 PHP112 PHP113 PHP114 PHP115 PHP116 PHP117 PHP119 PHP12 PHP120 PHP121 PHP122 PHP123 PHP124 PHP125 PHP126 PHP127 PHP128 PHP130 PHP131 PHP132 PHP133 PHP134 PHP135 PHP136 PHP137 PHP138 PHP139 CSD, Boulogne-Billancourt, NA, France Merck & Co., Inc., Kenilworth, NJ, UCB, Brussels, NA, Belgium Gilead, Foster City, CA, Humana, Louisville, KY, Salix Pharmaceuticals, Inc., Raleigh, NC, Center for Pharmaceuticals Outcomes Research, Aurora, CO, UCB, Brussels, NA, Belgium The Leona M and Harry B Helmsley Charitable Trust, New York City, NY, Astellas Pharma EMEA, London, NA, UK Janssen Scientifi c Affairs, LLC, Titusville, NJ, AbbVie. Inc., North Chicago, IL, National Center for Pharmaceutical Access and Management, Department of Health, Manila, NA, Philippines Bristol Myers Squibb, Santiago, NA, Chile Janssen-Cilag GmbH, Neuss, NA, Germany AbbVie, Mettawa, IL, CTI Clinical Trial and Consulting Services, Cincinnati, OH, Helmsley Charitable Trust, New York, NY, Meritage PharmaInc., San Diego, CA, Bristol-Myers Squibb, Shanghai, NA, China Astellas Pharma EMEA, London, NA, UK AbbVie Inc., North Chicago, IL, AbbVie Inc., North Chicago, IL, Merck, Kenilworth, NJ, Korea Institute for Health and Social Affairs, Seoul, NA, South Korea; Korea Research Foundation, Daejun, NA, South Korea Janssen Scientifi c Affairs, LLC, Titusville, NJ, JnJ Medical AP, Singapore, NA, Singapore Janssen Scientifi c Affairs, LLC, Titusville, NJ, PhRMA Foundation, Washington, DC, Remap Consulting, Bern, NA, Switzerland Celgene Corporation, Summit, NJ, CBPartners, New York, NY, Celgene Corporation, Summit, NJ, Tianjin Municipal Science and Technology Commission, Tianjin, NA, China Local Health Authority of Parma, Parma, NA, Italy AdvaMed, Washington, D.C., DC, Great Lakes University of Kisumu I, Kisumu, NA, Kenya Food and Drug Administration, Washington, DC, WHO, Geneva, NA, Switzerland Academy of Managed Care Pharmacy, Alexandria, VA, ; National Pharmaceutical Council, Washington, DC, ; International Society for Pharmacoeconomics and Outcomes Research, Lawrenceville, NJ, Creativ-Ceutical Ltd., London, NA, UK PHP14 PHP140 PHP141 PHP142 PHP143 PHP144 PHP145 PHP146 PHP147 PHP148 PHP149 PHP15 PHP150 PHP151 PHP152 PHP153 PHP154 PHP155 PHP156 PHP157 PHP158 PHP159 PHP160 PHP161 PHP162 PHP163 PHP164 PHP165 PHP166 PHP167 PHP168 PHP169 PHP17 PHP170 PHP171 PHP172 PHP173 PHP174 PHP175 PHP176 PHP177 PHP178 PHP179 PHP18 PHP180 PHP181 PHP182 PHP183 PHP184 PHP185 PHP186 PHP187 PHP188 PHP189 PHP19 PHP190 PHP191 PHP192 PHP194 PHP2 PHP20 PHP21 PHP22 PHP23 PHP24 PHP25 PHP26 PHP27 PHP28 PHP29 PHP3 PHP30 PHP31 PHP32 PHP33 PHP34 PHP35 PHP37 PHP38 Xcenda, Palm Harbor, FL, Abacus International, Bicester, NA, UK Korean Research-based Pharmaceutical Industry Association, Seoul, NA, South Korea Market Access Solutions LLC, London, NA, UK Celgene Corporation, Summit, NJ, Janssen-Cilag Polska, Warsaw, NA, Poland National Fund for Research and Technology in Chile (Fondecyt), Santiago, NA, Chile National Fund for Research and Technology in Chile, Santiago, NA, Chile FONDECYT, Santiago, NA, Chile National Council of Science and Technology, México D.F., NA, Mexico National Pharmaceutical Council, Washington, DC, Celgene Corporation, Warren, NJ, Genome Canada, Ottawa, ON, Canada; Natural Sciences and Engineering Research Council of Canada (NSERC), Ottawa, ON, Canada BMS, Stockholm, NA, Sweden Janssen Australia, Sydney, NA, Australia Novartis Pharmaceuticals, Guatemala, NA, Guatemala Ministry of Science and Technology, Taipei, NA, Taiwan Christiana Care Health System, Newark, DE, King Abdullah International Medical Research Center (KAIMRC), Riyadh, NA, Saudi Arabia RTI Health Solutions, Research Triangle Park, NC, Daiichi Sankyo, Parsippany, NJ, Industrial Chamber of Argentine Pharmaceutical Laboratories (CILFA)., Buenos Aires, NA, Argentina

5 A312 PHP39 PHP4 PHP40 PHP41 PHP42 PHP43 PHP44 PHP45 PHP46 PHP47 PHP48 PHP49 PHP5 PHP50 PHP51 PHP52 PHP53 PHP54 PHP55 PHP56 PHP57 PHP58 PHP59 PHP6 PHP60 PHP61 PHP62 PHP63 PHP64 PHP65 PHP66 PHP67 PHP7 PHP70 PHP71 PHP72 PHP73 PHP74 PHP75 PHP76 PHP77 PHP78 PHP79 PHP8 PHP80 PHP81 PHP82 PHP83 PHP84 PHP85 PHP86 PHP87 PHP88 PHP89 PHP9 PHP90 PHP92 PHP93 PHP94 PHP95 PHP96 PHP97 PHP98 PHP99 PHS1 PHS10 PHS101 PHS102 PHS103 PHS104 PHS105 PHS106 PHS107 PHS108 PHS109 PHS11 PHS110 PHS111 PHS112 PHS114 PHS115 PHS116 PHS117 PHS118 United BioSource Corporation, Blue Bell, PA, ; Express Scripts Corporation, St. Louis, MO, PhRMA, Washington, DC, Brazilian Ministry of Health, Brasilia, NA, Brazil GVK Biosciences, Hyderabad, NA, India Zoetis LLC, Florham Park, NJ, Pfi zerinc.., New York, NY, PhRMA, Washington, DC, Pfi zer Inc., New York, NY, ; PhRMA, Washington, DC, Multiple Pharmaceutical Companies, Seattle, WA, National Institutes of Health, Bethesda, MD, Pfi zer Inc., New York, NY, Agency for Healthcare Research & Quality, Rockville, MD, Edwards Life Sciences, Irvine, CA, United BioSource Corporation, Blue Bell, PA, Blue Cross Blue Shield of MA foundation, Boston, MA, Becton Dickinson, Franklin Lakes, NJ, Johnson and Johnson Medical Companies, Markham, ON, Canada Truven Health Analytics, Inc., Cambridge, MA, A consortium of pharmaceutical and device companies to the University of Washington, Various, NA, Global Outcomes Group, Inc., Reston, VA, UNICEF, Almaty, NA, Kazakhstan; Kazakh Academy of Nutrition, Almaty, NA, Kazakhstan Ministry of Health (DGOS), Paris, NA, France GlaxoSmithKline, RTP, NC, National Institute of General Medical Sciences, Bethesda, MD, National Pharmaceutical Council, Washington, DC, Merck & Co., Inc., Rahway, NJ, Decision Resources Group, London, NA, UK +helpharma, Medellin, NA, Colombia Aga Khan University Hospital, Karachi, NA, Pakistan Great Lakes University of Kisumu and CDC/KEMRI, NAIROBI, NA, Kenya Merck & Co. Inc., Rahway, NJ, Roche, Buenos Aires, NA, Argentina Shandong University, Jinan, NA, China PHS119 PHS12 PHS120 PHS121 PHS123 PHS124 PHS125 PHS126 PHS127 PHS128 PHS129 PHS13 PHS130 PHS131 PHS132 PHS133 PHS134 PHS135 PHS136 PHS138 PHS139 PHS14 PHS140 PHS141 PHS142 PHS143 PHS144 PHS145 PHS146 PHS147 PHS149 PHS15 PHS150 PHS151 PHS152 PHS153 PHS154 PHS155 PHS156 PHS157 PHS158 PHS159 PHS16 PHS160 PHS161 PHS162 PHS163 PHS165 PHS166 PHS167 PHS168 PHS169 PHS17 PHS170 PHS171 PHS172 PHS173 PHS174 PHS175 PHS176 PHS178 PHS179 PHS18 PHS19 PHS2 PHS20 PHS21 PHS22 PHS23 PHS24 PHS25 PHS26 PHS27 PHS28 PHS29 PHS3 PHS30 PHS31 Audifarma S.A, Pereira, NA, Colombia; Universidad Tecnológica de Pereira, Pereira, NA, Colombia; Colciencias, Bogota, NA, Colombia Pan American Health Organization, Washington, D.C., WA, Wellcare, Tampa, FL, ; HealthFirst, New York City, NY, ; Gateway Health, Pittsburgh, PA, ; Blue Cross Blue Shield Minnesota and Blue Plus, St. Paul, MN, ; Health Care Services Corporation, Chicago, IL, ; Cigna-HealthSpring, Franklin, TN, Blue Cross Blue Shield of MA foundation, Boston, MA, Bayer, Beijing, NA, China Novartis Pharmaceuticals UK Limited, Frimley, NA, UK Independence Blue Cross, Philadelphia, PA, Health promotion foundation, Ulaanbaatar, NA, Mongolia Bayer, Beijing, NA, China AbbVie, Mettawa, IL, Medical Research Council UK, London, NA, UK China Health Insurance Research Association, Beijing, NA, China Texas Health and Human Services Commission, Austin, TX, Independence Blue Cross, Philadelphia, PA, Coomeva Group, Bogota, NA, Colombia Komoto Family Foundation, Bakersfi eld, CA, Robert Wood Johnson Foundation, Princeton, NJ, DGOS, Paris, NA, France AstraZeneca Canada Inc., Mississauga, ON, Canada Great Lakes University of Kisumu I, Nairobi, NA, Kenya Great Lakes University of Kisumu and CDC/KEMRI, Nairobi, NA, Kenya Mississippi Division of Medicaid, Jackson, MS, Mekelle University, Mekelle, NA, Ethiopia University of Alabama at Birmingham & Birmingham VA Medical Center, Birmingham, AL, Mississippi Division of Medicaid, Jackson, MS, Amgen Inc., Thousand Oaks, CA, Medica Research Institute, Minneapolis, MN, Janssen, Titusville, NJ, Hospital Sisters Health System - Southern Illinois Division, Belleville, IL, National Institutes of Health, Bethsda, MD, Agency for Healthcare Research and Quality, Rockville, MD, Amgen, Inc.., Thousand Oaks, CA, IDeA-CTR award from the National Institute of General Medical Sciences, U54GM104942, Bethesda, MD, Management Sciences for Health, Windhoek, NA, Namibia Independence Blue Cross, Philadelphia, PA, NIA-NIH, Bethesda, MD, ; DoD, Fort Detrick, MD, AbbVie, North Chicago, IL, AHRQ, Rockville, MD, ; NIH, Rockville, MD, TEVA Pharmaceuticals, Frazer, PA, RTI Health Solutions, Research Triangle Park, NC,

6 A313 PHS33 Bristol-Myers Squibb, Lima, NA, Peru PHS34 PHS35 BAYER, WHIPPANY, NJ, PHS36 Cooperative Agreement-The Task Force TEPHINET CDC, Guatemala, NA, Guatemala PHS37 PHS38 PHS39 Ministry of Health, Singapore, NA, Singapore PHS4 PHS40 PHS41 PHS42 PHS43 PHS44 PHS45 PHS46 PHS47 Hologic, Inc., Marlborough, MA, PHS48 Hologic, Inc., Marlborough, MA, PHS49 Brain Sentinel, San Antonio, TX, PHS5 PHS50 PHS51 Am, TH, CA, PHS52 Merck, Kenilworth, NJ, PHS54 National Concil for Scientifi c and Technological Development (CNPq), Brasilia, NA, Brazil PHS55 SaludCoop Group, Bogota, NA, Colombia PHS56 PHS59 AHRQ CERT, Rockville, MD, PHS6 PHS60 Brazilian National Council for Scientifi c and Technological Development (CNPq), Brasília, NA, Brazil; Foundation for Research Support of the State of Minas Gerais (FAPEMIG), Belo Horizonte, NA, Brazil; Coordination for the Improvement of Higher Education Personnel (CAPES), Brasília, NA, Brazil PHS61 NPS MedicineWise, Sydney, NA, Australia PHS62 PHS63 Roche Diagnostics, Burgess Hill, NA, UK PHS64 PHS65 The National Board of Health and Welfare, Stockholm, NA, Sweden PHS66 Foundation for Research Support of the State of Minas Gerais (FAPEMIG), Belo Horizonte, NA, Brazil; Brazilian National Council for Scientifi c and Technological Development (CNPq), Brasília, NA, Brazil PHS67 PHS68 AbbVie, Mettawa, IL, PHS69 Amgen Inc., Thousand Oaks, CA, PHS7 NIHR Health Technology Assessment Programme, London, NA, UK PHS70 Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefi eld, CT, PHS71 PHS72 National Cancer Institute, Bethesda, MD, ; National Institute of Health, Bethesda, MD, ; Janice Davis Gordon fellowship, Houston, TX, PHS73 Walgreens, Deerfi eld, IL, PHS74 Pfi zer, Chino, CA, PHS75 PHS76 PHS77 PHS78 PHS79 PHS8 PHS80 Ministry of Health of Singapore, Singapore, NA, Singapore PHS81 Palo Alto Medical Foundation, Mountain View, CA, PHS82 Great Lakes University of Kisumu and CDC/KEMRI, NAIROBI, NA, Kenya PHS83 Canadian Institutes for Health Research, Ottawa, ON, Canada PHS84 PHS85 Teva Pharmaceuticals Inc., Malvern, PA, PHS86 PHS87 PHS88 PHS89 PHS9 PHS90 PHS91 Brazilian Ministry of Health/CNPq, Brasilia, NA, Brazil PHS92 PHS93 PHS94 PHS95 PHS96 PHS97 Actelion Pharmaceuticals US Inc., South San Francisco, CA, PHS98 NIMH R21MH098755, Washington, DC, PHS99 PIH1 PIH10 PIH11 PIH12 PIH13 PIH14 PIH15 PIH16 PIH18 PIH19 PIH2 PIH20 PIH21 PIH22 PIH23 PIH24 PIH25 PIH26 PIH27 PIH28 PIH29 PIH3 PIH30 PIH31 PIH32 PIH33 PIH34 PIH35 PIH36 PIH37 PIH38 PIH39 PIH4 PIH40 PIH41 PIH42 PIH43 PIH44 PIH45 PIH46 PIH47 PIH48 PIH49 PIH5 PIH50 PIH51 PIH53 PIH54 PIH55 PIH56 PIH57 PIH58 PIH59 PIH6 PIH60 PIH61 PIH62 PIH63 PIH64 PIH65 PIH7 PIH9 PIN1 PIN10 PIN100 PIN101 PIN102 PIN103 PIN104 PIN105 PIN106 PIN107 PIN108 PIN109 PIN11 PIN110 PIN111 PIN112 PIN113 PIN12 PIN13 PIN14 PIN15 PIN16 PIN17 PIN18 PIN19 PIN2 PIN21 PIN22 PIN23 Merck Sharp & Dohme, Mexico, NA, Mexico AbbVie, North Chicago, IL, Universiti Sains Malaysia, Penang, NA, Malaysia AllazoHealth, New York, NY, Cerner Corporation, Kansas City, MO, Moffi tt Cancer Center, Tampa, FL, Moffi tt Cancer Center, Tampa, FL, Kantar Health, New York City, NY, Moffi tt Cancer Center, Tampa, FL, Moffi tt Cancer Center, Tampa, FL, Zoetis LLC, Florham Park, NJ, Optum (formerly QualityMetric), Lincoln, RI, Moffi tt Cancer Center, Tampa, FL, AbbVie Inc., North Chicago, IL, NIH, Bethesda, MD, Genelex, Inc., Seattle, WA, Truven Health Analytics, Inc., Ann Arbor, MI, Bayer HealthCare Pharmaceuticals, Whippany, NJ, AbbVie, North Chicago, IL, CNPQ, Fortaleza, NA, Brazil GlaxoSmithKline Biologicals SA, Wavre, NA, Belgium National Science and Technology Major Project, Beijing, NA, China Merck, West Point, PA, Merck, West Point, PA, HERON Commercialization, London, NA, UK AstraZeneca, Gaithersburg, MD, The Medicines Company, Parsippany, NJ, The Medicines Company, Parsippany, NJ, Smith & Nephew Inc., Fort Worth, TX, Janssen, Beerse, NA, Belgium Cubist Pharmaceuticals, Lexington, MA, Abbvie Inc., Saint-Laurent, QC, Canada Smith & Nephew Inc., Fort Worth, TX, Smith & Nephew Inc., Fort Worth, TX,

7 A314 PIN24 PIN25 Smith & Nephew Inc., Fort Worth, TX, PIN26 Merck & Co., Inc., West Point, PA, PIN27 PIN28 CONACYT, Ciudad de México, NA, Mexico PIN29 Abbvie Canada, Saint-Laurent, QC, Canada PIN3 Pfi zer SAS, Bogotá, NA, Colombia PIN30 GlaxoSmithKline Biologicals SA, Wavre, NA, Belgium PIN31 African Economic Research Consortium (AERC), Nairobi, NA, Kenya PIN32 The Medicines Company, Parsippany, NJ, PIN33 Astellas, Chertsey, NA, UK PIN34 PIN35 PIN37 PIN38 PIN39 Instituto Nacional de Salud, Bogotá DC, NA, Colombia PIN40 Agency for Healthcare Research and Quality, Rockville, MD, PIN41 PIN42 Bristol-Myers Squibb, Shanghai, NA, China PIN43 PIN44 Masr El Kheir Non Profi t Foundation, Cairo, NA, Egypt PIN45 Pfi zer, Makati, NA, Philippines PIN46 Abbott Laboratories, Abbott Park, IL, PIN47 PIN48 Transfusion Research Capacity in Africa (T-REC), Liverpool, NA, UK PIN49 Pfi zer Inc., New York, NY, PIN5 AbbVie, Saint-Laurent, QC, Canada PIN50 AbbVie Inc., North Chicago, IL, PIN51 PIN52 PIN53 PIN54 PIN55 Pfi zer Investment Co. Ltd., Beijing, NA, China PIN56 AstraZeneca, Moscow, NA, Russia PIN57 Jump Trading Simulation and Education Center Corridor of Innovation Grant, Peoria, IL, PIN58 Pfi zer SAS, Bogotá, NA, Colombia PIN59 Pfi zer, New York, NY, PIN6 PIN60 PIN62 PIN63 PIN65 PIN66 Pfi zer Chile S.A., Santiago, NA, Chile PIN67 Bristol-Myers Squibb Pharmaceuticals Ltd., Princeton, NJ, PIN68 Bristol-Myers Squibb Pharmaceuticals Ltd., Uxbridge, NA, UK PIN69 Bristol-Myers Squibb Pharmaceuticals Ltd., Uxbridge, NA, UK PIN7 PIN70 PIN71 PIN72 PIN73 Bristol-Myers Squibb Pharmaceuticals Ltd, Princeton, NJ, PIN74 Cubist Pharmaceuticals, Lexington, MA, PIN75 Sanofi Pasteur, Swiftwater, PA, PIN76 Pfi zer, Santiago, NA, Chile PIN78 American Society of Health-System Pharmacists (ASHP) Foundation, Bethesda, MD, PIN79 PIN8 PIN80 Mekelle University, Mekelle, NA, Ethiopia PIN81 PIN82 Merck Sharp & Dohme Limited, Whitehouse Station, NJ, PIN83 Actelion, Allschwil, NA, Switzerland; Basilea, Basel, NA, Switzerland; Cempra, Chapel Hill, NC, ; Cerexa, Oakland, CA, ; Cubist, Lexington, MA, ; Durata, Chicago, IL, ; Merck, Sharpe and Dohme, Rahway, NJ, ; Nabriva, Vienna, NA, Austria; Trius Therapeutics, San Diego, CA, ; PhRMA, Washington, DC, PIN84 Actelion, Allschwil, NA, Switzerland; Basilea, Basel, NA, Switzerland; Cempra, Chapel Hill, NC, ; Cerexa, Oakland, CA, ; Cubist, Lexington, MA, ; Durata, Chicago, IL, ; Merck, Sharp and Dohme, Rahway, NJ, ; Nabriva, Vienna, NA, Austria; Trius Therapeutics, San Diego, CA, ; PhRMA, Washington, DC, PIN85 AbbVie Inc., North Chicago, IL, PIN86 FDA, Silver Spring, MD, PIN87 Janssen, Beerse, NA, Belgium PIN88 Melinta Therapeutics, Inc., Lincolnshire, IL, PIN9 Higher Education Commission, Islamabad, NA, Pakistan PIN90 Decision Resources Group, Burlington, MA, PIN91 Decision Resources Group, Burlington, MA, PIN92 PIN93 PIN94 Cubist Pharmaceuticals, Lexington, MA, PIN95 PIN96 PIN97 Ministry of Education - LRGS, Putrajaya, NA, Malaysia PIN98 GlaxoSmithKline, Mississauga, ON, Canada PIN99 The Mecicines Company, Parsippany, NJ, PMD1 PMD10 Smith & Nephew Inc., Fort Worth, TX, PMD11 Smith & Nephew Inc., Fort Worth, TX, PMD12 PMD13 Integrated Diagnostics, Inc., Seattle, WA, PMD14 Proteus Digital Health, Redwood City, CA, PMD15 Boston Scientifi c, Marlborough, MA, PMD16 Ethicon Biosurgery, Somerville, NJ, PMD17 Roche Molecular Systems, Pleasanton, CA, PMD18 Johnson and Johnson Medical Companies, Markham, ON, Canada PMD19 Johnson and Johnson Medical Companies, Markham, ON, Canada PMD2 PMD20 Becton Dickinson, Franklin Lakes, NJ, PMD21 Ethicon, Inc., Somerville, NJ, PMD22 CR Bard, Murray Hill, NJ, PMD23 Roche Molecular Systems, Inc., Pleasanton, CA, PMD24 Immucor, Inc., Norcross, GA, PMD25 Lifescan, a Johnson & Johnson company, Wayne, PA, PMD26 Seikagaku Corporation, Tokyo, NA, Japan PMD27 W.L. Gore & Associates, Inc., Flagstaff, AZ, PMD28 Johnson & Johnson Medical Mexico, Mexico City, NA, Mexico PMD29 Johnson & Johnson Medical Mexico, Mexico City, NA, Mexico PMD3 PMD30 Medtronic, Inc., Minneapolis, MN, PMD31 Organogenesis, Canton, MA, PMD32 Autonomic Technologies, Inc., Redwood City, CA, PMD33 PMD34 PMD35 Ministry of Health, Bogota, NA, Colombia; Colciencias, Bogota, NA, Colombia; IETS, Bogota, NA, Colombia PMD36 Boston Scientifi c, Marlborough, MA, PMD37 PMD38 PMD39 PMD4 Hologic, Inc., Marlborough, MA, PMD40 Medtronic, Minneapolis, MN, PMD41 PMD42 Medtronic, Mexico, NA, Mexico PMD43 Derma Sciences, Princeton, NJ, PMD44 Medtronic, Mexico, AL, Mexico PMD45 Republican Center for Health Development, Astana, NA, Kazakhstan PMD46 Department of Health, Australia, Canberra, NA, Australia PMD47 British Heart Foundation, London, NA, UK PMD48 PMD49 Dobrin Consulting, Richmond, VA, PMD5 PMD51 PMD52 PMD53 PMD54 PMD55 Medtronic, Inc., Mounds View, MN, PMD56 PMD57 TEVA, Amsterdam, NA, Netherlands PMD58 PMD59 PMD6 PMD60 SPR Therapeutics, Cleveland, OH, PMD61 Anthem, Indianapolis, IN, PMD62 PMD63 PMD64 PMD65 PMD66 Genomic Health, Inc., Redwood City, CA, PMD67 PMD68 PMD69 Johnson & Johnson Medical, Buenos Aires, NA, Argentina PMD7 PMD70 PMD71 PMD72 PMD73 PMD74 LifeCell, an Acelity Company, Bridgewater, NJ, PMD75 Medtronic Italia S.p.A., Milan, NA, Italy PMD76 Becton Dickinson, Franklin Lakes, NJ, PMD77 Ethicon Biosurgery, Somerville, NJ, PMD78 PMD79 Ethicon Biosurgery, Somerville, NJ, PMD8 PMD80 Wellspect HealthCare, Mölndal, NA, Sweden PMD81 PMD82 Agency for Healthcare Research and Quality, Rockville, MD,

8 A315 PMD9 PMH1 PMH10 PMH11 PMH12 PMH13 PMH14 PMH15 PMH16 PMH17 PMH18 PMH19 PMH2 PMH20 PMH21 PMH22 PMH23 PMH24 PMH25 PMH26 PMH27 PMH28 PMH29 PMH3 PMH30 PMH31 PMH32 PMH33 PMH34 PMH35 PMH36 PMH37 PMH38 PMH39 PMH4 PMH40 PMH41 PMH42 PMH43 PMH44 PMH45 PMH46 PMH47 PMH48 PMH49 PMH5 PMH50 PMH51 PMH52 PMH53 PMH54 PMH55 PMH56 PMH57 PMH58 PMH59 PMH6 PMH60 PMH61 PMH62 PMH63 PMH64 PMH65 PMH66 PMH67 PMH68 PMH69 PMH7 PMH70 PMH71 PMH72 PMH73 PMH74 PMH75 PMH76 PMH77 PMH78 PMH79 Eisai Inc., Woodcliff Lake, NJ, Lundbeck, Paris, NA, France AHRQ, Rockville, MD, Pfi zer Investment Co., Ltd., Beijing, NA, China University of Ghana Offi ce of Research, Innovation and Development, Accra, NA, Ghana Agency for Healthcare Research and Quality (AHRQ), Rockville, MD, Otsuka Pharma Scandinavia, Stockholm, NA, Sweden Sunovion Pharmaceuticals Inc., Marlborough, MA, European Comission, Bruxelles, NA, Belgium Janssen Scientifi c Affairs LLC, Titusvlle, NJ, Forest Research Institute, Jersey City, NJ, Janssen Scientifi c Affairs, LLC, Titusville, NJ, Eli Lilly and Company, Indianapolis, IN, Forest Research Institute, Jersey City, NJ, Pfi zer, Inc., New York, NY, Forest Research Institute, Jersey City, NJ, Takeda Pharmaceutical Company, Ltd, Deerfi eld, IL, ; and H Lundbeck A/S, Deerfi eld, IL, ; Analysis Group,Inc.., Montreal, NA, Canada Reckitt Benckiser Pharmaceuticals, Richmond, VA, NIHR, Southampton, NA, UK Janssen Scientifi c Affairs, Titusville, NJ, University of Washington, Seattle, WA, University of Washington, Seattle, WA, ; Allergan, Irvine, CA, Lundbeck SAS, Issy-les-moulineaux, NA, France National Health and Medical Research Council, Canberra, NA, Australia Forest Research Institute, Inc.., a Subsidiary of Actavis PLC, Jersey City, NJ, Janssen Scientifi c Affairs, LLC, Titusville, NJ, National Institute of Mental Health, Rockville, MD, Sunovion, Marlborough, MA, Takeda Pharmaceuticals Company Ltd, Deerfi eld, IL, ; H Lundbeck A/S, Valby, NA, Denmark Pfi zer, Inc., New York, NY, Pfi zer Japan Inc., Tokyo, NA, Japan H. Lundbeck A/S, Valby, NA, Denmark Cerner, Kansas City, MO, The AmeriHealth Caritas Family of Companies, Philadelphia, PA, Eli Lilly and Company, Indianapolis, IN, Auburn University, Auburn, AL, Washington State Attorney General's Offi ce, Olympia, WA, Janssen Scientifi c Affairs, LLC, Titusville, NJ, Lilly Suzhou Pharmaceutical Company, Ltd., Shanghai, NA, China KJT Group, Inc., Honeoye Falls, NY, NIH, Bethesda, MD, NIH, Bethesda, NA, Cabinet for Health and Family Services, Frankfort, KY, Mississippi Division of Medicaid, Jackson, MS, PMH8 Lundbeck, Paris, NA, France PMH80 PMH9 University of Pennsylvania School of Medicine (Adjunct), Philadelphia, PA, ; Purdue Pharma L.P., Stamford, CT, PMS1 PMS10 Pfi zer Inc., New York, NY, PMS11 Pfi zer, Inc., New York, NY, PMS12 PMS13 PMS14 Pfi zer SAS, Bogotá, NA, Colombia PMS15 PMS16 PMS17 PMS18 PMS19 Novartis Pharmaceuticals, EAS Hanover, NJ, PMS2 Pfi zer SAS, Bogotá, NA, Colombia PMS20 Histogenics Corporation, Waltham, MA, PMS21 PMS22 PMS23 PMS24 Agency for Healthcare Research and Quality, Rockville, MD, PMS25 Amgen Inc., Thousand Oaks, CA, PMS26 IPSEN Pharma, Boulogne-Billancourt, NA, France PMS27 Pfi zer SAS, Bogotá, NA, Colombia PMS28 PMS29 Celgene Corporation, Warren, NJ, PMS3 Bristol Myers Squibb (BMS), Plainsboro, NJ, PMS30 PMS31 Pfi zer Inc., New York, NY, PMS32 Ceterix Orthopaedics, Inc., Menlo Park, CA, PMS33 Pfi zer, Tadworth, NA, UK PMS34 Pfi zer Inc., New York, NY, PMS35 Pfi zer Chile S.A., Santiago, NA, Chile PMS36 PMS37 PMS38 PMS39 Medtronic Advanced Energy, Portsmouth, NH, PMS4 Bristol Myers Squibb (BMS), Plainsboro, NJ, PMS40 Medtronic Advanced Energy, Portsmouth, NH, PMS41 AHRQ R18 grant, Salt Lake City, UT, PMS42 Ethicon, Cincinnati, OH, PMS43 Pacira, Boston, IL, PMS44 PMS45 Audifarma S.A, Pereira, NA, Colombia; Universidad Tecnológica de Pereira, Pereira, NA, Colombia PMS46 Pfi zer Inc., New York, NY, PMS47 Pfi zer, New York, NY, PMS48 Genentech, Inc., South San Francisco, CA, PMS49 Seikagaku Corporation, Tokyo, NA, Japan PMS5 PMS50 Pfi zer Chile S.A., Santiago, NA, Chile PMS51 PMS52 PMS53 PMS54 Pfi zer Central America and Caribbean, San José, NA, Costa Rica PMS55 Abbvie Inc., North Chicago, IL, PMS56 Pfi zer, São Paulo, NA, Brazil PMS57 Ministry of Science and Technology, Taipei, NA, Taiwan PMS58 Pfi zer Central America and Caribbean, San Jose, NA, Costa Rica PMS59 PMS6 Pfi zer Colombia, Bogotá, NA, Colombia; Audifarma S.A, Pereira, NA, Colombia; Universidad Tecnológica de Pereira, Pereira, NA, Colombia PMS60 AbbVie, Saint-Laurent, QC, Canada PMS61 PMS62 PMS63 PMS64 PMS65 AbbVie Slovakia, Bratislava, NA, Slovak Republic PMS66 AbbVie Slovakia, Bratislava, NA, Slovak Republic PMS67 Pfi zer, Montreal, QC, Canada PMS68 PMS69 Clementia Pharmaceuticals,Inc.., Boston, MA, PMS7 PMS70 Quintiles, Durham, NC, PMS71 Eli Lilly, Indianapolis, IN, PMS72 Department of Science and Technology, Chandigarh, NA, India PMS73 PMS74 PMS75 PMS76 Decision Resources Group, Burlington, MA, PMS77 Decision Resources Group, Burlington, MA, PMS78 PMS79 PMS8 PMS80 Eli Lilly & Company, Indianapolis, IN, PMS81

9 A316 PMS82 PMS83 PMS84 PMS85 PMS86 PMS87 PMS88 PMS89 PMS9 PMS90 PMS91 PMS92 PND1 PND10 PND11 PND12 PND13 PND14 PND15 PND17 PND18 PND19 PND2 PND20 PND21 PND22 PND23 PND24 PND25 PND27 PND28 PND29 PND3 PND30 PND31 PND32 PND33 PND34 PND35 PND36 PND37 PND38 PND39 PND4 PND40 PND41 PND42 PND43 PND44 PND45 PND46 PND47 PND48 PND49 PND5 PND50 PND51 PND52 PND53 PND54 PND55 PND56 PND57 PND58 PND59 PND6 PND60 PND61 PND62 PND63 PND65 PND66 PND67 PND68 PND69 PND7 PND70 PND71 PND72 PND73 PND74 PND75 Amgen, Thousand Oaks, CA, Celgene Corporation, Warren, NJ, Amgen, Thousand Oaks, CA, Amgen Canada Inc., Mississauga, ON, Canada Avanir, Aliso Viejo, CA, Genzyme, a Sanofi company, Cambridge, MA, Biogen Idec International GmbH, Zug, NA, Switzerland Genzyme, a Sanofi company, Cambridge, MA, Genzyme, a Sanofi Company, Cambridge, MA, Biogen Idec, Boston, MA, Merck & Co., Inc., North Wales, PA, AdverseEvents, Inc. Santa Rosa, CA, EMD Serono, Inc. (a subsidiary of Merck KGaA, Darmstadt, Germany), Rockland, MA, Eisai,Inc., Woodcliff Lake, NJ, 2Medtronic International, Tolochenaz, NA, Switzerland Impax Laboratories, Inc., Hayward, CA, AbbVie Ltd., Dublin, NA, Ireland Biogen Idec, Weston, MA, Shire, Wayne, PA, Teva Pharmaceuticals B.V., Amsterdam, NA, Netherlands Avanir Pharmaceuticals, Inc., Aliso Viejo, CA, University of Ottawa, Ottawa, ON, Canada; Canadian Institutes of Health Research, Ottawa, ON, Canada Novartis, East Hanover, NJ, Amgen Inc., Thousand Oaks, CA, Sunovion Pharmaceuticals Inc., Marlborough, MA, National Institutes of Health, Bethesda, MD, Genome Canada, Ottawa, ON, Canada Novartis, East Hanover, NJ, Bayer Pharma AG, Berlin, NA, Germany Ministry of Health, Bogota, NA, Colombia; Colciencias, Bogota, NA, Colombia; IETS, Bogota, NA, Colombia Pfi zer Consumer Healthcare, Madison, NJ, Alnylam Pharmaceuticals, Cambridge, MA, Bayer Pharma AG, Berlin, NA, Germany Sunovion Pharmaceuticals, Inc., Marlborough, MA, Sunovion Pharmaceuticals Inc., Marlborough, MA, AstraZeneca Pharmaceuticals, LP, Wilmington, DE, Mapi Research Trust, Lyon, NA, France Companion Dx, Houston, TX, Pfi zer, Inc., New York, NY, Pfi zer, Inc., New York, NY, Acorda Therapeutics, Ardsley, NY, Avanir Pharmaceuticals, Inc., Aliso Viejo, CA, ; OptiNose US Inc., Yardley, PA, Acorda Therapeutics, Inc., Ardsley, NY, Sunovion Pharmaceuticals Inc., Marlborough, MA, Truven Health Analytics, Cambridge, MA, PND76 PND77 PND8 PND9 PP1 PP2 PP3 PP4 PRM1 PRM10 PRM100 PRM101 PRM102 PRM103 PRM104 PRM105 PRM106 PRM107 PRM108 PRM109 PRM11 PRM110 PRM111 PRM112 PRM113 PRM114 PRM115 PRM116 PRM117 PRM118 PRM119 PRM12 PRM120 PRM121 PRM122 PRM123 PRM124 PRM125 PRM126 PRM127 PRM128 PRM129 PRM13 PRM130 PRM131 PRM132 PRM133 PRM134 PRM135 PRM136 PRM137 PRM138 PRM139 PRM140 PRM141 PRM142 PRM143 PRM144 PRM145 PRM146 PRM147 PRM148 PRM149 PRM15 PRM150 PRM151 PRM152 PRM153 PRM154 PRM155 PRM156 PRM16 PRM17 PRM18 PRM19 PRM2 PRM20 PRM21 PRM22 EMD Serono, Inc. (a subsidiary of Merck KGaA, Darmstadt, Germany), Rockland, MA, ; Pfizer Inc., New York, NY, Impax Laboratories, Inc., Hayward, CA, Genentech, South San Francisco, CA, GlaxoSmithKline, West Point, PA, Agency for Healthcare Research and Quality, Rockville, MD, Center for Medicine in the Public Interest, New York, NY, AstraZeneca, Fort Washington, PA, Cubist Pharmaceuticals, Lexington, MA, Food and Health Bureau, Hong Kong, NA, Hong Kong Sucampo Pharma Americas LLC, Bethesda, MD, PHT Corporation, Boston, MA, ; Optum Insights, Lincoln, RI, Shire, Lexington, MA, Novartis, East Hanover, NJ, MedAvante, Munich, NA, Germany Eli Lilly, Indianapolis, IN, Meda Pharmaceutical, Somerset, NJ, Cenbiotech, Dijon, NA, France Xcenda, Palm Harbor, FL, Bayer Yakuhin Ltd., Osaka, NA, Japan Colciencias, Colombia, Pereira, NA, Colombia; Universidad Tecnologica de Pereira, Pereira, NA, Colombia ICON, Dublin, NA, Ireland ICON PLC, Oxford, NA, UK RTI-Health Solutions, Research Triangle Park, NC, Avivia, Mexico City, NA, Mexico Eli Lilly, Indianapolis, IN, Eli Lilly, Indianapolis, IN, Eli Lilly, Indianapolis, IN, Merck & Co., Kenilworth, NJ, Novartis, East Hanover, NJ, Optum, Eden Prairie, MN, Jordan University of Science & Technology, Irbid, NA, Jordan EMD Serono, Inc.. (a subsidiary of Merck KGaA, Darmstadt, Germany), Rockland, MA, Children's Hospital Los Angeles, Los Angeles, CA, Eli Lilly and Company, Indianapolis, IN, MaRS EXCITE, Toronto, ON, Canada Merck & Co.,Inc., North Wales, PA, EuroQol Research Foundation, Rotterdam, NA, Netherlands Forest Research Institute, Inc.., a subsidiary of Actavis plc, Jersey City, NJ, ; Ironwood Pharmaceuticals, Inc., Cambridge, MA, Fonds de recherche du Québec - Santé (FRQS), Montréal, QC, Canada; McLaughlin Centre for Population Health Risk Assessment, Ottawa, ON, Canada; University of Ottawa, Ottawa, ON, Canada Novartis, East Hanover, NJ, Janssen Pharmaceuticals Incorporated, Raritan, NJ,

10 A317 PRM23 PRM24 PRM25 PRM26 PRM27 PRM28 PRM29 PRM3 PRM30 PRM31 PRM32 PRM33 PRM34 PRM35 PRM36 PRM37 PRM38 PRM39 PRM4 PRM40 PRM41 PRM43 PRM44 PRM45 PRM46 PRM47 PRM48 PRM49 PRM5 PRM50 PRM51 PRM52 PRM53 PRM54 PRM55 PRM56 PRM57 PRM59 PRM6 PRM60 PRM61 PRM62 PRM63 PRM64 PRM65 PRM66 PRM67 PRM68 PRM69 PRM7 PRM70 PRM71 PRM72 PRM73 PRM74 PRM75 PRM76 PRM77 PRM78 PRM79 PRM8 PRM81 PRM82 PRM83 PRM84 PRM85 PRM87 PRM88 PRM89 PRM9 PRM90 PRM91 PRM92 PRM93 PRM94 PRM95 PRM96 PRM97 National Council for Scientifi c and Technological Development (CNPq), Brasilia, NA, Brazil Merck & Co., Inc., West Point, PA, Costello Medical Consulting, Cambridge, NA, UK Eli Lilly, Indianapolis, IN, Coomeva Group, Bogota, NA, Colombia; Coomeva Group, Cali, NA, Colombia Chugai Pharmaceutical Co., Ltd, Tokyo, NA, Japan EMD Serono, Inc.. (a subsidiary of Merck KGaA, Darmstadt, Germany), Rockland, MA, Research Manitoba, Winnipeg, MB, Canada Mayo Clinic, Rochester, MN, Mapi Research Trust, Lyon, NA, France Bristol-Myers Squibb, Plainsboro, NJ, Excerpta Medica, Amsterdam, NA, Netherlands Anolinx, Murray, UT, IMS Health, Plymouth Meeting, PA, CSD, boulogne-billancourt, NA, France Mississippi-DUR, Jackson, MS, Astellas Pharma SA, Madrid, NA, Spain University of Leicester, Leicester, NA, UK National Cancer Institute at the National Institutes of Health, Bethesda, MD, ; Agency for Healthcare Research and Quality, Rockville, MD, ; Breast Cancer Research Foundation, New York, NY, ; Foundation for Barnes Jewish Hospital, St. Louis, MO, Eisai, Woodcliff Lake, NJ, Novartis Pharma AG, Basel, NA, Switzerland Anolinx LLC, Salt Lake City, UT, Pfi zer, Inc., New York, NY, Merck & Co. Inc., White House Station, NJ, AstraZeneca, North Ryde, NA, Australia GSK, King of Prussia, PA, Medical Research Council, London, NA, UK; National Institute for Health Research, London, NA, UK NOVO Nordisk, Plainsboro, NJ, Novartis Pharma, Basel, NA, Switzerland Abbott, Waukegan, IL, H Lundbeck A/S, Valby, NA, Denmark Children's Hospital Los Angeles, Los Angeles, CA, The Medicines Company, Waltham, MA, Zafgen, Inc.., Boston, MA, Actelion Pharmaceuticals US, Inc., San Francisco, CA, Incyte Corporation, Wilmington, DE, Bayer Pharma AG, Berlin, NA, Germany Critical Path Institute, Tucson, AZ, Actelion Pharmaceuticals Ltd, Allschwil, NA, Switzerland Purdue Pharma L.P., Stamford, CT, Patient Centered Outcomes Research Institute, Washington, DC, PRM98 PRM99 PRS1 PRS10 PRS11 PRS12 PRS13 PRS14 PRS16 PRS17 PRS18 PRS19 PRS2 PRS20 PRS21 PRS22 PRS23 PRS24 PRS25 PRS26 PRS27 PRS28 PRS29 PRS3 PRS30 PRS31 PRS32 PRS34 PRS35 PRS36 PRS37 PRS38 PRS39 PRS4 PRS40 PRS41 PRS42 PRS43 PRS44 PRS45 PRS46 PRS47 PRS48 PRS49 PRS5 PRS50 PRS51 PRS52 PRS53 PRS6 PRS7 PRS8 PRS9 PSS1 PSS10 PSS11 PSS12 PSS13 PSS14 PSS15 PSS16 PSS17 PSS18 PSS19 PSS2 PSS20 PSS21 PSS22 PSS23 PSS24 PSS25 PSS26 PSS27 PSS28 PSS29 PSS3 PSS30 PSS31 PSS32 PSS33 PSS34 PSS35 PSS36 PSS37 PSS38 PSS39 PSS4 FDA/CBER, Silver Spring, MD, Amerihealth Caritas, Philadelphia, PA, Sunovion Pharmaceuticals, Inc., Marlborough, MA, Teva Pharmaceuticals B.V., Amsterdam, NA, Netherlands Boehringer Ingelheim, Mexico City, NA, Mexico Meda Pharmaceuticals, Somerset, NJ, CSL Behring, King of Prussia, PA, Cempra, Inc., Chapel Hill, NC, Novartis, Mexico, NA, Mexico Boehringer Ingelheim, Ingelheim, NA, Germany UNC Eshelman School of Pharmacy, Chapel Hill, NC, Pfi zer Japan Inc., Tokyo, NA, Japan Novartis Farmacéutica, Mexico, NA, Mexico Bayer Healthcare Pharmaceuticals, Whippany, NJ, Novartis AG Pharma, Basel, NA, Switzerland 2Novartis Pharmaceuticals Inc., Dorval, NA, Canada Teva, Frazer, PA, PHT Corporation, Boston, MA, Novartis Pharmaceuticals Inc., Dorval, NA, Canada Novartis Pharma AG, Basel, NA, Switzerland Kantar Health, New York, NY, Mapi Research Trust, Lyon, NA, France Novartis Pharmaceuticals, East Hanover, NJ, Housing and Urban Development, Washington, DC, Pfi zer, Beijing, NA, China Mylan Specialty LP, Canonsburg, PA, Novartis, East Hanover, NJ, Bayer Healthcare Pharmaceuticals, Whippany, NJ, Celgene Corporation, Warren, NJ, Genentech, Inc., South San Francisco, CA, Zoetis, Florham Park, NJ, Bayer Pharma AG, Berlin, NA, Germany Allergan, Inc., Irvine, CA, Novartis, Taipei, NA, Taiwan Bayer Turk Kimya San. Ltd. Sti, Istanbul, NA, Turkey Novartis Pharmaceuticals Canada Inc., Dorval, QC, Canada Novartis, UK, NA, UK Centers for Disease Control and Prevention, Atlanta, GA, Bayer Turk Kimya San. Ltd. Sti, Istanbul, NA, Turkey National Clinical Guideline Centre, London, NA, UK Novartis, UK, NA, UK NIH, Bethesda, MD, Amgen Inc., Thousand Oaks, CA, AbbVie, North Chicago, IL, Allergan, Irvine, CA, Genentech, South San Francisco, CA, Genentech, Inc., South San Francisco, CA, GlaxoSmithKline, Research Triangle Park, NC, Pfi zer, Surrey, NA, UK Pfi zer, Surrey, NA, UK Zoetis, Florham Park, NJ, Celgene Corporation, Warren, NJ,

11 A318 PSS40 PSS41 PSS42 PSS43 PSS5 PSS6 PSS7 PSS8 PSS9 PSY1 PSY10 PSY11 PSY12 PSY13 PSY14 PSY15 PSY16 PSY17 PSY18 PSY19 PSY2 PSY20 PSY21 PSY22 PSY23 PSY24 PSY25 PSY26 PSY27 PSY28 PSY29 PSY3 PSY30 PSY31 PSY32 PSY33 PSY34 PSY36 PSY37 PSY38 PSY39 PSY4 PSY40 PSY41 PSY42 PSY43 PSY44 PSY45 PSY46 PSY47 PSY48 PSY49 PSY5 PSY50 PSY51 PSY52 PSY53 PSY54 Melinta Therapeutics, New Haven, CT, Amgen, Thousand Oaks, CA, National Eye Institute, Bethesda, MD, Stiefel, a GSK Company, Brentford, NA, UK Biogen Idec Inc., Cambridge,, MA, Pfi zer Japan Inc., Tokyo, NA, Japan VIVUS, Inc., Mountain View, CA, Novartis, East Hanover, NJ, Novo Nordisk Inc., Plainsboro, NJ, Biogen Idec, Weston, MA, Baxter Healthcare Corporation, Deerfi eld, IL, Johnson & Johnson (Ethicon), Cincinnati, OH, Astellas Pharma EMEA, London, NA, UK Eisai Inc., Woodcliff Lake, NJ, Pfi zer Inc., Groton, CT, The Medicines Company, Waltham, MA, Pfi zer Investment Co., Ltd., Beijing, NA, China Janssen, São Paulo, NA, Brazil Pfi zer, New York, NY, Iroko Pharmaceuticals, Philadelphia, PA, Purdue Pharma L.P., Stamford, CT, Eli Lilly and Company, Indianapolis, IN, VIVUS, Inc., Mountain View, CA, Novo Nordisk, Boston, MA, AstraZeneca, London, NA, UK National Institute of Nursing Research, Bethesda, DC, NIH, Bethesda, MD, Novartis Pharmaceuticals Corporation, East Hannover, NJ, Catamaran, Schaumburg, IL, Janssen Inc., Toronto, ON, Canada Janssen Scientifi c Affairs, LLC, Horsham, PA, Janssen Research & Development LLC, Raritan, NJ, PSY55 PSY56 PSY57 PSY58 PSY59 PSY6 PSY60 PSY61 PSY62 PSY63 PSY64 PSY65 PSY66 PSY67 PSY68 PSY69 PSY7 PSY70 PSY71 PSY72 PSY73 PSY74 PSY75 PSY76 PSY77 PSY78 PSY79 PSY8 PSY80 PSY81 PSY82 PSY83 PSY84 PSY85 PSY9 PUK10 PUK11 PUK12 PUK13 PUK14 PUK15 PUK16 PUK17 PUK18 PUK19 PUK2 PUK20 PUK4 PUK5 PUK6 PUK7 PUK8 PUK9 Janssen Scientifi c Affairs, LLC, Horsham, PA, Novo Nordisk Inc., Plainsboro, NJ, Lupus-Italy (Gruppo Italiano per la Lotta al LES)), Piacenza, NA, Italy Foundation for Barnes Jewish Hospital, St. Louis, MO, ; Agency for Healthcare Research and Quality, Rockville, MO, ; National Cancer Institute at the National Institutes of Health, Bethesda, MD, USC-ASPIRE, Columbia, SC, ; FDA, Silver Spring, MD, Purdue Pharma, L.P., Stamford, CT, Novartis Pharmaceuticals Canada Inc., Dorval, QC, Canada Centers for Disease Control and Prevention, Atlanta, GA, AstraZeneca, Fort Washington, PA, Amgen Canada Inc., Mississauga, ON, Canada Pfi zer Inc., New York, NY, HERON Commercialization, London, NA, UK Janssen Scientifi c Affairs, LLC, Titusville, NJ, NIPER, S.A.S. Nagar (Mohali), Punjab, NA, India Astellas Pharma SA, Madrid, NA, Spain Astellas Pharma, Leiden, NA, Netherlands Astellas Scientifi c and Medical Affairs, Inc., Northbrook, IL, Astellas Pharma SA, Madrid, NA, Spain Department of Biotechnology, New Delhi, NA, India NIHR TCC, Leeds, NA, UK Astellas Pharma EMEA, London, NA, UK Astellas Pharma EMEA, London, NA, UK Alexion Pharmaceuticals Inc., Cheshire, CT, CSD, boulogne-billancourt, NA, France