VALUE IN HEALTH 20 (2017) A384 A397

Transcription

1 A384 VALUE IN HEALTH 20 (2017) A384 A397 DISCLOSURE INFORMATION Research Presentations Financial Disclosure Statements The International Society for Pharmacoeconomics and Outcomes Research asked all abstract contributors to disclose fi nancial support for their research. The following fi nancial support was declared: AD1 AD2 AD3 AD4 CE1 CE2 CE3 CE4 CN1 CN2 CN3 CN4 CS1 CS2 CS3 CS4 CV1 CV2 CV3 CV4 DB1 DB2 DB3 DB4 IN1 IN2 IN3 IN4 MD1 MD2 MD3 MD4 ME1 ME2 ME3 ME4 MH1 MH2 MH3 MH4 MO1 MO2 MO3 MO4 PCN1 PCN10 PCN100 PCN101 PCN102 PCN103 PCN104 PCN105 PCN106 PCN107 PCN108 PCN109 PCN11 PCN110 PCN111 PCN112 PCN113 PCN114 Walgreens Co., Deerfi eld, IL, Cigna Health and Life Insurance Company, Bloomfi eld, CT, National Institute on Minority Health and Health Disparities of the National Institutes of Health under Award Number G12MD , Bethesda, MD, National Institute of Health Research, UK Genomic Health, Redwood City, CA, CERCIT, Austin, TX, Novartis Inc., East Hanover, NJ, Abbvie, Chicago, IL, Amgen, Thousand Oaks, CA, Johnson and Johnson, New Brunswick, NJ, Harvard University, Boston, MA, University of Tennessee Health Science Center, Memphis, TN, Xcenda, Palm Harbor, FL, Novo Nordisk A/S, Søborg, Denmark Vapotherm, Inc., Exeter, NH, FDA, Silver Spring, MD, Health Quality Ontario, Toronto, ON, Canada Abbott, Sylmar, CA, Medtronic, INC., Minneapolis, MN, Johnson & Johnson, New Brunswick, NJ, Merck KGaA, Darmstadt, Germany; Pfizer Inc., New York, NY, Johnson & Johnson, New Brunswick, NJ, Abbott Nutrition, Columbus, OH, Janssen Global Services, LLC, Raritan, NJ, Eisai Inc., Woodcliff Lake, NJ, F. Hoffman-La Roche Ltd., Basel, Switzerland Promotion of the ICTUS study was supported by the University Hospital Centre of Toulouse, Toulouse, France; Data collection for ICTUS STUDY supported by pharmaceutical consortium (Eisai, Janssen, Lundbeck, and Novartis), ; Otsuka Pharmaceutical Europe Ltd., Wexham, UK; Data collection for ICTUS STUDY supported Novartis, East Hanover, NJ, AstraZeneca, Cotia, Brazil Genentech, South San Francisco, CA, China Primary Health Care Foundation, Shanghai, China Institute for Clinical and Economic Review, Boston, MA, Boehringer Ingelheim, Sao Paulo, Brazil Novartis Oncology, US, East Hanover, NJ, Shire, Cambridge, MA, Medivation, Inc., which was acquired by Pfi zer, Inc., San Francisco, CA, ; Astellas Pharma, Inc., Northbrook, IL, Astellas Pharma, Inc., Northbrook, IL, ; Medivation, Inc., which was acquired by Pfi zer, Inc., San Francisco, CA, PCN115 PCN116 PCN117 PCN118 PCN119 PCN12 PCN120 PCN121 PCN122 PCN123 PCN124 PCN125 PCN126 PCN127 PCN128 PCN129 PCN13 PCN130 PCN131 PCN132 PCN133 PCN134 PCN135 PCN136 PCN137 PCN138 PCN139 PCN14 PCN140 PCN141 PCN142 PCN143 PCN144 PCN145 PCN146 PCN147 PCN148 PCN149 PCN15 PCN150 PCN151 PCN152 PCN153 PCN154 PCN155 PCN156 PCN157 PCN158 PCN159 PCN16 PCN160 PCN161 PCN162 PCN163 PCN164 PCN165 PCN166 PCN167 PCN168 PCN169 PCN17 PCN170 PCN171 PCN172 PCN173 PCN174 PCN175 Merck KGaA, Darmstadt, Germany; Pfi zer Inc., New York, NY, Eli Lilly and Company, Surrey, UK Janssen-Cilag NV, Beerse, Belgium Array BioPharma, Cambridge, MA, Roche, Hong Kong, Hong Kong Boehringer Ingelheim, Sao Paulo, Brazil Boehringer Ingelheim, Sao Paulo, Brazil Merck KGaA, Darmstadt, Germany; Pfi zer Inc., New York, NY, Genome Canada, Ottawa, ON, Canada; Genome British Columbia, Vancouver, BC, Canada; Canadian Institutes of Health Research, Ottawa, ON, Canada; BC Cancer Foundation, Vancouver, BC, Canada; Canadian Centre for Applied Research in Cancer Control, Vancouver, BC, Canada Intuitive Surgical, Sunnyvale, CA, Pharmamar S.A., Colmenar Viejo, Spain Hoffmann-La Roche, Mississauga, ON, Canada Pfi zer, Beijing, China JnJ Medical AP, Singapore, Singapore Pierre Fabre Medicament (China), Shanghai, China Health Quality Ontario, Toronto, ON, Canada Bristol-Myers Squibb, Dubai, United Arab Emirates Millenium Pharmaceuticals, Cambridge, MA, Genome Canada, Canada, QC, Canada Bristol-Myers Squibb, Princeton, NJ, Novartis Pharmaceuticals Corporation, East Hanover, NJ, Gilead Sciences Canada, Mississauga, ON, Canada Castle Biosciences, Inc., Friendswood, TX, Lilly, Indianapolis, IN, Jazz Pharmaceuticals, Palo Alto, CA, Novartis Pharmaceuticals Corporation, East Hanover, NJ, Merck & Co., INC., North Wales, PA, Janssen Pharmaceutica NV, Beerse, Belgium Victorian Cancer Agency, Melbourne, Australia Life Cell, Bridgewater, NJ, Amgen Inc., Thousand Oaks, CA, Sanofi Genzyme, Bridgewater, NJ, Genentech, Inc., South San Francisco, CA, National Medical Research Council, Singapore, Singapore Astellas Pharmaceuticals, Northbrook, IL, Millenium Pharmaceuticals; a wholly-owned subsidiary of Takeda Pharmaceutical Company Limited, Cambridge, MA, Copyright 2017, International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc.

2 VALUE IN HEALTH 20 (2017) A384 A397 A385 PCN176 PCN177 PCN178 PCN179 PCN18 PCN180 PCN181 PCN182 PCN183 PCN184 PCN185 PCN186 PCN187 PCN188 PCN189 PCN19 PCN190 PCN191 PCN192 PCN193 PCN194 PCN195 PCN196 PCN197 PCN198 PCN199 PCN2 PCN20 PCN200 PCN201 PCN202 PCN203 PCN204 PCN205 PCN206 PCN207 PCN208 PCN209 PCN21 PCN210 PCN211 PCN212 PCN213 PCN214 PCN215 PCN216 PCN217 PCN218 PCN219 PCN22 PCN220 PCN221 PCN222 PCN223 PCN224 PCN225 PCN226 PCN227 PCN228 PCN229 PCN23 PCN230 PCN231 PCN232 PCN233 PCN234 PCN235 PCN236 PCN237 PCN238 PCN239 PCN24 PCN240 PCN241 PCN242 PCN243 PCN244 PCN245 Medivation, Inc., which was acquired by Pfi zer, Inc., San Francisco, CA, ; Astellas Pharma, Inc., Northbrook, IL, Novartis Pharmaceuticals Corporation, East Hanover, NJ, Korea Health Industry Development Institute, Chungcheongbukdo, South Korea Merrimack Pharmaceuticals, Inc., Cambridge, MA, Intuitive Surgical, Sunnyvale, CA, Merck KGaA, Darmstadt, Germany; Pfizer Inc., New York, NY, Merrimack Pharmaceuticals, Inc., Cambridge, MA, AstraZeneca, Gaithersburg, MD, Ariad, Cambridge, MA, AstraZeneca, Gaithersburg, MD, Celgene Corporation, Summit, NJ, Merck KGaA, Darmstadt, Germany; Pfizer Inc., New York, NY, Novartis Pharmaceuticals Corporation, East Hanover, NJ, Amgen, Thousand Oaks, CA, Amgen, Thousand Oaks, CA, Novartis Pharmaceuticals, East Hanover, NJ, Amgen, Thousand Oaks, CA, Pfi zer, Inc., New York, NY, Johnson & Johnson (Ethicon), Cincinnati, OH, Ministry of Science and Technology, Taipei, Taiwan BAYER S.A., Bogota, Colombia MKTXS, Raritan, NJ, Prostate Cancer Canada, Montreal, QC, Canada Takeda Pharmaceutical Company Limited, Cambridge, MA, Bristol-Myers Squibb Co, Princeton, NJ, Bristol-Myers Squibb, Princeton, NJ, Bristol-Myers Squibb, Sol Sweden Novartis, East Hanover, NJ, Johnson & Johnson Medical, New Brunswick, NJ, Johnson & Johnson, New Brunswick, NJ, PhRMA, Washington, DC, NIH, Washington, DC, Laura and John Arnold Foundation, Houston, TX, QuintilesIMS, Sao Paulo, Brazil Tadeka, Cambridge, MA, Celldex, Hampton, NJ, (Medivation was acquired by Pfi zer, Inc., in September 2016), San Francisco, CA, ; Astellas Pharma, Inc., Northbrook, IL, Navigant Consulting, Inc., Boston, MA, Novartis Pharmaceuticals Corporation, East Hanover, NJ, Pfi zer Inc., New York, NY, The TPG-NPRT (National Payor Roundtable), Glastonbury, CT, Moffi tt Cancer Center, Tampa, FL, ; Prostate Cancer Foundation, Santa Monica, CA, Bristol-Myers Squibb, Plainsboro, NJ, Navigant Life Sciences, Boston, MA, PCN246 PCN247 PCN248 PCN249 PCN25 PCN250 PCN251 PCN252 PCN253 PCN254 PCN255 PCN256 PCN257 PCN258 PCN259 PCN26 PCN260 PCN261 PCN262 PCN263 PCN264 PCN265 PCN266 PCN267 PCN268 PCN269 PCN27 PCN270 PCN271 PCN272 PCN273 PCN274 PCN275 PCN276 PCN277 PCN278 PCN279 PCN28 PCN280 PCN281 PCN282 PCN283 PCN284 PCN285 PCN286 PCN29 PCN3 PCN30 PCN31 PCN32 PCN33 PCN34 PCN35 PCN36 PCN37 PCN38 PCN39 PCN4 PCN40 PCN41 PCN42 PCN43 PCN44 PCN45 PCN46 PCN47 PCN48 PCN49 PCN5 PCN50 PCN51 PCN52 PCN53 PCN54 PCN55 Quintiles IMS, Kirkland, QC, Canada Access Infi nity Ltd., London, UK Incyte, Wilmington, DE, Incyte, Wilmington, DE, Drug Intelligence Inc., Toronto, ON, Canada SIRIUS Market Access, London, UK Astellas Pharma, Inc., Northbrook, IL, ; Medivation, Inc., which was acquired by Pfi zer, Inc., San Francisco, CA, Envision Pharma Group, Philadelphia, PA, ; Cardinal Health, Dublin, OH, Envision Pharma Group, Philadelphia, PA, ; RealHealthData, Santa Cruz, CA, Biodesi, Boulder, CO, National Cancer Institute, Bethesda, MD, Ipsen Pharma SAS, Boulogne-Billancourt, France Millennium Pharmaceuticals, Inc., Cambridge, MA,, a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, Cambridge, MA, Bristol-Myers Squibb, Princeton, NJ, Genentech, South San Francisco, CA, 1Millennium Pharmaceuticals, Inc., Cambridge, MA,, a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, Cambridge, MA, Bristol-Myers Squibb, Princeton, NJ, Novartis Pharmaceuticals Corporation, East Hanover, NJ, ARIAD Pharmaceuticals, Inc., Cambridge, MA, Novartis, East Hanover, NJ, Novartis de Colombia, Bogota, Colombia Otsuka Pharmaceuticals, Wexham, UK; Sirius Market Access, London, UK MKTXS, Raritan, NJ, Roche, Taipei, Taiwan Merck & Co., Kenilworth, NJ, AstraZeneca, Gaithersburg, MD, Otsuka Pharmaceuticals, Wexham, UK Astellas Pharma, Inc., Northbrook, IL, ; Medivation, Inc., which was acquired by Pfi zer, Inc., San Francisco, CA, Genentech, South San Francisco, CA, Pfi zer Inc., New York, NY, ; Merck KGaA, Darmstadt, Germany Bristol-Myers Squibb, Lawrenceville, NJ, Bristol-Myers Squibb, Princeton, NJ, Carl-Zeiss Meditec AG, Oberkochen, Germany Merck Sharp & Dhome, Bogota, Colombia

3 A386 VALUE IN HEALTH 20 (2017) A384 A397 PCN56 PCN57 PCN58 PCN59 PCN6 PCN60 PCN61 PCN62 PCN63 PCN64 PCN65 PCN66 PCN67 PCN68 PCN69 PCN7 PCN70 PCN71 PCN72 PCN73 PCN74 PCN75 PCN76 PCN77 PCN78 PCN79 PCN8 PCN80 PCN81 PCN82 PCN83 PCN84 PCN85 PCN86 PCN87 PCN88 PCN89 PCN9 PCN90 PCN91 PCN92 PCN93 PCN94 PCN95 PCN96 PCN97 PCN98 PCN99 PCV1 PCV10 PCV100 PCV101 PCV102 PCV103 PCV104 PCV105 PCV106 PCV107 PCV108 PCV109 PCV11 PCV110 PCV111 PCV112 PCV113 PCV114 PCV115 PCV116 PCV117 PCV118 PCV119 PCV12 PCV120 PCV121 PCV122 PCV13 PCV14 PCV15 PCV16 PCV17 F. Hoffmann-La Roche AG, Basel, Switzerland Eisai Inc., Woodcliff Lake, NJ, Novartis Oncology (China), Beijing, China Genentech, Inc., South San Francisco, CA, Novartis Chi Beijing, China Novartis Chi Beijing, China Genentech, South San Francisco, CA, Johnson and Johnson, New Brunswick, NJ, Janssen Cilag SA, Bogota, Colombia NCI, Bethesda, MD, Pharmamar S.A., Colmenar Viejo, Spain Johnson & Johnson, New Brunswick, NJ, Bristol-Myers Squibb, Princeton, NJ, AstraZeneca, Sao Paulo, Brazil Bristol-Myers Squibb, New York, NY, Hoffmann-La Roche, Mississauga, ON, Canada Bristol-Myers Squibb, New York, NY, Janssen, Raritan, NJ, AstraZeneca, Cotia, Brazil Richter-Gedeon Nyrt, Budapest, Hungary; KTIA- NAP (Hungarian Brain Research Program), Budapest, Hungary Novosys Health, Green Brook, NJ, Jordan University of Science & Technology, Irbid, Jordan The University of Texas at Austin, Austin, TX, Bristol-Myers Squibb, Princeton, NJ, Bristol-Myers Squibb Co, Princeton, NJ, The University of Texas at Austin, Austin, TX, Amgen Inc., Thousand Oaks, CA, Medtronic Advanced Energy, Portsmouth, NH, Novartis, New Jersey, NJ, Bayer, São Paulo, Brazil AstraZeneca, Cotia, Brazil Actelion Pharmaceuticals, South San Francisco, CA, Sanofi, Bridgewater, NJ, ; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, Sanofi Chi Shanghai, China Pfi zer Investment Co., Ltd., Beijing, China Ministry of Health, Labour and Welfare, Tokyo, Japan SVARE Chair, University of Calgary, Calgary, AB, Canada The TPG-NPRT (National Payor Roundtable), Glastonbury, CT, National Institute of General Medical Sciences, Bethesda, MD, Pfi zer Investment Co., Ltd., Beijing, China Baxter Healthcare Corporation, Deerfi eld, IL, Baxter Healthcare Corporation, Deerfi eld, IL, Portola, South San Francisco, CA, Bayer Healthcare Company Ltd., Beijing, China Pharmaceutical Research & Manufacturer s of America (PhRMA), Washington, DC, Malaysia Ministry of Higher Education, Kuala Lumpur, Malaysia Amgen, Thousand Oaks, CA, Pfi zer Investment Co., Ltd., Beijing, China PCV18 Amgen Inc., Thousand Oaks, CA, PCV19 Janssen Scientifi c Affairs, LLC, Raritan, NJ, PCV2 PCV20 PCV21 AstraZeneca, Dubai, United Arab Emirates PCV22 PCV23 National Institute of General Medical Sciences, Bethesda, MD, PCV24 PCV25 Amarin Pharma, Inc., Bedminster, NJ, PCV26 PCV27 Hong Kong Research Grant Council, Hong Kong, Hong Kong PCV28 Amgen, Thousand Oaks, CA, PCV29 Amgen Inc., Thousand Oaks, CA, PCV3 PCV30 PCV31 Amgen Inc., Thousand Oaks, CA, PCV32 PCV33 Regeneron, Eastview, NY, ; Sanofi Pharmaceuticals, Paris, France PCV34 PCV35 Universidad CEU Cardenal Herrera, Moncada (Valencia), Spain PCV36 Amgen Inc., Thousand Oaks, CA, PCV37 PCV38 Bayer Healthcare Company Ltd., Beijing, China PCV39 PCV4 PCV40 PCV41 PCV42 Cardiovascular Systems Inc., St. Paul, MN, PCV43 Cardiovascular Systems Inc., St. Paul, MN, PCV44 Pfi zer, New York, NY, ; Bristol-Myers Squibb, Plainsboro, NJ, PCV45 Cardiovascular Systems Inc., St. Paul, MN, PCV46 Boehringer-Ingelheim Pharmaceuticals Inc., Ridgefi eld, CT, PCV47 Cardiovascular Systems Inc., St. Paul, MN, PCV48 Cardiovascular Systems Inc., St. Paul, MN, PCV49 Novartis Healthcare Philippines, Inc., Makati City, Philippines PCV5 PCV50 Zoetis, Parsippany, NJ, PCV51 Greenvalley, Shanghai, China PCV52 PCV53 PCV54 Novartis, Beijing, China PCV55 PCV56 Bayer Chi Beijing, China PCV57 Novartis Argenti Buenos Aires, Argentina PCV58 Regeneron Pharmaceuticals, Inc., Tarrytown, NY, ; Sanofi, Bridgewater, NJ, PCV59 PCV6 PCV60 PCV61 Boehringer Ingelheim GmbH, Ingelheim, Germany PCV62 Sanofi, Shanghai, China PCV63 Amgen Bulgaria EOOD, Sofi a, Bulgaria PCV64 Sanofi, Bridgewater, NJ, ; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, PCV65 PCV66 PCV67 PCV68 Pfi zer, Beijing, China PCV69 Relypsa, Inc., a Vifor Pharma Company, Redwood City, CA, PCV7 Cardiovascular Systems, Inc., St. Paul, MN, PCV70 Bayer, Bogota, Colombia PCV71 PCV72 PCV73 Actelion Pharmaceuticals, South San Francisco, CA, PCV74 PCV75 PCV76 PCV77 PCV78 Bayer Vital GmbH, Leverkusen, Germany PCV79 PCV8 Anthem, Indianapolis, IN, PCV80 Amgen, Thousand Oaks, CA, PCV81 PCV82 PCV83 Brigham and Women's Hospital, Boston, MA, PCV84 PCV85 PCV86 PCV87 Chulalongkorn University, Bangkok, Thailand PCV88 National Heart, Lung, and Blood Institute (NHLBI), Bethesda, MD, PCV89 China Pharmaceutical University, Nanjing, China PCV9 NIHR Schools of Public Health, London, UK

4 VALUE IN HEALTH 20 (2017) A384 A397 A387 PCV90 Anthem, Indianapolis, IN, PCV91 PCV92 Pfi zer, Beijing, China PCV93 PCV94 PCV95 PCV96 Novartis, East Hanover, NJ, PCV97 Sanofi, Shanghai, China PCV98 PCV99 World Health Organization, Tunis, Tunisia PDB1 PDB10 AstraZeneca, Fort Washington, PA, PDB11 PDB12 Malaysia Ministry of Higher Education, Kuala Lumpur, Malaysia PDB13 GlaxoSmithKline, Collegeville, PA, ; Optum, Eden Prairie, MN, PDB14 Astrazeneca, Wilmington, DE, PDB15 PDB16 PDB17 PDB18 PDB19 PDB2 National Natural Science Foundation of Chi Beijing, China; Thousand Youth Talents Plan of Chi Beijing, China; Young Investigator Award, Sichuan University, Chengdu, China PDB20 PDB21 PDB22 PDB23 PDB24 PDB25 PDB26 PDB27 PDB28 Young Investigator Award of Sichuan University, Chengdu, China; "Thousand Youth Talents Plan of Chi Beijing, China; National Natural Science Foundation of Chi Beijing, China PDB29 PDB3 National Natural Science Foundation of Chi Beijing, China; Thousand Youth Talents Plan of Chi Beijing, China; Young Investigator Award of Sichuan University, Chengdu, China PDB30 Sanofi, Paris, France PDB31 PDB32 NovoNordisk, São Paulo, Brazil PDB33 PDB34 PDB35 PDB36 NOVONORDISK, SANTIAGO, Chile PDB37 Lilly Suzhou Pharmaceutical Co, Ltd., Shanghai, China PDB38 AstraZeneca, Wilmington, DE, PDB39 Merck, North Wales, PA, PDB4 PDB40 Eli Lilly and Company, Shanghai, China PDB41 Eli Lilly and Co., Indianapolis, IN, PDB42 National Institute for Diabetes Digestive and Kidney Diseases, Bethesda, MD, PDB43 PDB44 PDB45 Ministry of Science and Technology, Taipei, Taiwan PDB46 PDB47 PDB48 PDB49 Chalapathi Pharmacy College, Guntur, IN, India PDB5 PDB50 PDB51 Pfi zer, Sydney, Australia PDB52 AstraZeneca, Bogotá, D.C., Colombia PDB53 AstraZeneca, Bogotá, D.C., Colombia PDB54 AstraZeneca, Bogotá, D.C., Colombia PDB55 RTI-HS, Research Triangle Park, NC, ; GlaxoSmithKline, Collegeville, PA, PDB56 Merck & Co, Kenilworth, NJ, PDB57 PDB58 Pharmaceutical Research and Manufacturers of America Foundation (PhRMA), Washington, DC, PDB59 Xi'an Jiaotong University, Xian, China PDB6 PDB60 The University of Chicago, Chicago, IL, PDB61 PhRMA foundation, Washington, DC, DC, PDB62 PDB63 PDB64 PDB65 PCORI, Washington, DC, PDB66 Novo Nordisk, Søborg, Denmark PDB67 Novo Nordisk A/S, Søborg, Denmark PDB68 GlaxoSmithKline, Collegeville, PA, ; RTI-HS, Research Triangle Park, NC, PDB69 PDB7 PDB70 PDB71 PDB72 PDB73 PDB74 PDB75 PDB76 PDB77 PDB78 PDB79 PDB8 PDB80 PDB81 PDB82 PDB83 PDB84 PDB85 PDB86 PDB87 PDB88 PDB89 PDB9 PDB90 PDB91 PDB92 PDB93 PDB94 PGI1 PGI10 PGI11 PGI12 PGI13 PGI14 PGI15 PGI16 PGI17 PGI18 PGI19 PGI2 PGI20 PGI21 PGI22 PGI23 PGI24 PGI25 PGI26 PGI27 PGI28 PGI29 PGI3 PGI30 PGI31 PGI32 PGI33 PGI34 PGI35 PGI36 PGI37 PGI38 PGI39 PGI4 PGI40 PGI41 PGI42 PGI43 PGI5 PGI6 PGI7 PGI8 PGI9 PHP1 PHP10 PHP100 PHP101 PHP102 PHP103 PHP104 PHP105 Drug Intelligence Inc., Toronto, ON, Canada Kowa Pharmaceuticals, 530 Industrial Park Blvd, AL, Kowa Pharmaceuticals, Montgomery, AL, Eli Lilly and Company, Indianapolis, IL, University of Tennessee Health Science Center, Memphis, TN, Merck & Co., Inc., Kenilworth, NJ, Novo Nordisk Inc., Plainsboro, NJ, International Islamic University Malaysia, Kuantan, Malaysia Merck, north wales, PA, NovoNordisk, Copenhagen, Denmark Sanofi, Bridgewater, NJ, Adelphi Real World, Bollington, UK Shire, Inc., Wayne, PA, ; Southern California Permanente Medical Group, Pasadena, CA, Shire, Inc., Wayne, PA, ; Southern California Permanente Medical Group, Pasadena, CA, Southern California Permanente Medical Group, Pasadena, CA, ; Shire, Inc., Wayne, PA, UCB Biopharma, São Paulo, SP, Brazil Shire Inc., Wayne, PA, ; Southern California Permanente Medical Group, Pasadena, CA, Shire, Inc., Wayne, PA, ; Southern California Permanente Medical Group, Pasadena, CA, University of Rijeka, Rijeka, Croatia AstraZeneca, Wilmington, DE, Shionogi, London, UK Takeda Pharmaceuticals, Glattpark (Opfi kon), Switzerland Grifols, Inc., Research Triangle Park, NC, Shire, Inc., Wayne, PA, ; Southern California Permanente Medical Group, Pasadena, CA, Shionogi, London, UK Johnson & Johnson, Co., New Brunswick, NJ, ERT, Boston, MA, Pfi zer Inc., Groton, CT, Ironwood Pharmaceuticals, Inc., Cambridge, MA, ; Allergan, PLC, Jersey City, NJ, Shionogi, London, UK Synergy Pharmaceuticals Inc., New York, NY, Shire Human Genetic Therapies, Inc., Lexington, MA, Synergy Pharmaceuticals Inc., New York, NY, Pfi zer Inc., New York, NY, Shire Development LLC, Chesterbrook, PA, Kaiser Permanente Mid-Atlantic States, Rockville, MD, Duquesne University, Pittsburgh, PA, Takeda, Helsinki, Finland Fondazione FADE, Milano, Italy Janssen R&D, LLC, Titusville, NJ,

5 A388 VALUE IN HEALTH 20 (2017) A384 A397 PHP106 PHP107 PHP108 PHP109 PHP11 PHP110 PHP111 PHP112 PHP113 PHP114 PHP115 PHP116 PHP117 PHP118 PHP119 PHP12 PHP120 PHP121 PHP122 PHP123 PHP124 PHP125 PHP126 PHP127 PHP128 PHP129 PHP13 PHP130 PHP131 PHP132 PHP133 PHP134 PHP135 PHP136 PHP137 PHP138 PHP139 PHP14 PHP140 PHP141 PHP142 PHP143 PHP144 PHP145 PHP146 PHP147 PHP148 PHP149 PHP15 PHP150 PHP151 PHP152 PHP153 PHP154 PHP155 PHP156 PHP157 PHP158 PHP159 PHP16 PHP160 PHP161 PHP162 PHP163 PHP164 PHP165 PHP166 PHP167 PHP168 PHP169 PHP17 PHP170 PHP171 PHP172 PHP173 PHP174 PHP175 PHP176 PHP177 PHP178 PHP179 PHP18 Bayer, Bogota, Colombia MCPHS, Boston, MA, Excerpta Medica, Amsterdam, Netherlands Pharmaceutical Research and Manufacturers of America (PhRMA, Washington, DC, Cig Bloomfi eld, CT, Vifor Pharma, Zurich, Switzerland West Virginia University, Morgantown, WV, ; Marshall University, Huntington, WV, Laura and John Arnold Foundation, Houston, TX, Intuitive Surgical, Sunnyvale, CA, Niger Delta Development Commission, Port Harcourt, Nigeria Pan American Health Organization, Argentina; Ministry of Health of Argentina, Buenos Aires, Argentina California Department of Industrial Relations, Oakland, CA, Wyatt Health Management, Mississauga, ON, Canada National Health Insurance Administration, Taipei, Taiwan The National Pharmaceutical Council, Washington, DC, Australian Research Council, Canberra, Australia; Monash Faculty of Business, Melbourne, Australia; Bank West Curtin Economics Centre, Perth, Australia Universidad del Desarrollo, Santiago, Chile The Thailand Research Fund, Bangkok, Thailand PHP180 PHP181 Leonard D. Schaeffer Center for Health Policy & Economics, Los Angeles, CA, PHP182 PHP183 PHP184 PHP185 PHP186 PHP187 Intuitive Surgical, Sunnyvale, CA, PHP188 Universidad del Desarrollo, Santiago, Chile PHP189 IMI, Brussels, Belgium; NICE, Manchester, UK PHP19 IHS Global Ltd., Bracknell, UK PHP190 PHP191 PHP192 Universidad del Desarrollo, Santiago, Chile PHP193 PHP194 PHP195 PHP196 PHP197 GlaxoSmithKline, Research Triangle Park, NC, PHP198 Genentech, South San Francisco, CA, PHP199 PHP2 PHP20 Ministry of Food and Drug Safety, Osong, South Korea PHP200 WHO, Tehran, Iran PHP201 PHP202 PHP203 PHP204 PHP205 PHP206 PHP207 PHP208 PHP209 PHP21 PHP210 Health Research Board, Dublin, Ireland; EuroQol, Rotterdam, Netherlands PHP211 QuintilesIMS, Durham, NC, PHP212 PHP213 PHP214 PHP215 Nestle Health Science, Florham Park, NJ, PHP216 PHP217 PHP218 PHP219 PHP22 Arnold Foundation, Houston, TX, PHP220 PHP221 PHP222 GlaxoSmithKline, Research Triangle Park, NC, ; Johns Hopkins, Baltimore, MD, PHP223 Evidation Health, San Mateo, CA, PHP224 ERT, Boston, MA, PHP225 PHP226 PHP227 PHP228 PHP229 Amgen, Thousand Oaks, CA, PHP23 PHP230 Robert Wood Johnson Foundation, Princeton, NJ, PHP231 PHP232 PHP233 U.S Food and Drug Administration Grant # U01FD005555, Silver Spring, MD, PHP234 Finep, Brasília, Brazil PHP235 PHP236 PHP237 PHP238 PHP239 PHP24 PHP240 PHP241 PHP242 Janssen Pharmaceutical, Beerse, Belgium; Sanofi -Aventis, Bridgewater, NJ, ; Gilead Sciences, Foster City, CA, ; Amgen, Thousand Oaks, CA, ; Novartis, Basel, Switzerland; Biogen, Cambridge, MA, ; Pfi zer, New York City, NY, ; Vertex Pharmaceuticals, Boston, MA, PHP243 PHP244 PHP245 PHP246 PHP247 Center of Drug Evaluation, Taipei, Taiwan; EuroQol Research Foundation, Rotterdam, Netherlands PHP248 PHP249

6 VALUE IN HEALTH 20 (2017) A384 A397 A389 PHP25 PHP250 PHP251 PHP252 PHP253 PHP254 PHP255 PHP256 PHP257 PHP258 PHP259 PHP26 PHP260 PHP261 PHP262 PHP263 PHP264 PHP265 PHP266 PHP267 PHP268 PHP269 PHP27 PHP270 PHP271 PHP272 PHP273 PHP274 PHP275 PHP276 PHP277 PHP278 PHP279 PHP28 PHP280 PHP281 PHP282 PHP283 PHP284 PHP285 PHP286 PHP287 PHP288 PHP289 PHP29 PHP290 PHP291 PHP292 PHP293 PHP294 PHP295 PHP296 PHP297 PHP298 PHP299 PHP3 PHP30 PHP300 PHP301 PHP302 PHP303 PHP304 PHP305 PHP306 PHP307 PHP308 PHP309 PHP31 PHP310 PHP311 PHP312 PHP313 PHP314 PHP315 PHP316 PHP32 PHP33 PHP34 PHP35 PHP36 PHP37 PHP38 PHP39 PHP4 PHP40 PHP41 ERT, CHARLESTOWN, MA, Local Health Authority of Parma, Emilia-Romagna region, Italy Xcenda, Palm Harbor, FL, USFDA, Silver Spring, MD, Japan Society for the Promotion of Science, Tokyo, Japan Wyatt Health Management, Mississauga, ON, Canada EMD Serono, Inc. (a business of Merck KGaA, Darmstadt, Germany), Rockland, MA, University of Ottawa, Ottawa, ON, Canada CERSI Center UCSF, San Francisco, CA, AplusA Research, Lyon, France SIRIUS Market Access, London, UK MyCognition Ltd., London, UK VCLS, Camberley, UK Association of British Pharmaceutical Industry, London, UK Chalapathi institute of pharmaceutical sciences, GUNTUR, India Lupus UK, Romford, UK UNC Eshelman School of Pharmacy, Chapel Hill, NC, PAREXEL, London, UK Xcenda, LLC, Palm Harbor, FL, PHP42 National Pharmaceutical Council, Washington DC, DC, PHP43 PHP44 Lundbeck, LLC, Deerfi eld, IL, ; Otsuka Pharmaceuticals, Princeton, NJ, PHP45 PHP46 Lundbeck, LLC, Deerfi eld, IL, ; Otsuka Pharmaceuticals, Princeton, NJ, PHP47 PHP48 PHP49 PHP5 PHP50 King Abdullah International Medical Research Center, Riyadh, Saudi Arabia PHP51 The Medicines Company, Parsippany, NJ, PHP52 PHP53 PHP54 PHP55 US Food and Drug Administration, Silver Spring, MD, PHP56 PHP57 Military Suicide Research Consortium, Denver, PHP58 PHP59 PHP6 Navigant Consulting, Inc., Boston, MA, PHP60 PHP61 PhRMA, Washington, DC, PHP62 PHP63 PHP64 PHP65 The TPG-NPRT (National Payor Roundtable), Glastonbury, CT, PHP66 The TPG-NPRT (National Payor Roundtable), Glastonbury, CT, PHP67 Federal Government of Canada, Ottawa, ON, Canada PHP68 The Partnership to Fight Chronic Disease (PFCD), Washington, dc, DC, PHP69 PHP7 National Health Council, Washington, DC, PHP70 PHP71 Merck & Co., Inc., Kenilworth, NJ, PHP72 PHP73 Becton, Dickinson and Company, Shanghai, China PHP74 National Prescription Drug Utilization Information System, Canadian government, Ottawa, ON, Canada PHP75 PHP76 PhRMA, Washington, DC, PHP77 Walgreens Co., Deerfi eld, IL, PHP78 PHP79 PHP8 PHP80 PHP81 Pacira Pharmaceuticals, Inc., Parsippany, NJ, PHP82 Military Suicide Research Consortium, Denver, CO, ; VISN 2 Center of Excellence for Suicide Prevention, Canandaigua, NY, PHP83 PHP84 Johnson & Johnson, New Brunswick, NJ, PHP85 PHP86 ACHI, Little Rock, AR, PHP87 NIH/NHGRI, Bethesda, MD, PHP88 PHP89 PHP9 PHP90 PHP91 C.R. Bard Inc., Murray Hill, NJ, PHP92 PHP93 PHP94 Becton Dickinson (BD), Franklin Lakes, NJ, PHP95 PHP96 CNPq, Belo Horizonte, Brazil; Fapemig, Belo Horizonte, Brazil PHP97 Pacira Pharmaceuticals, Parsippany, NJ, PHP98 AHRQ, Rockville, MD, PHP99 PHS1 PHS10 MUTUAL SER EPS, Cartage, Colombia PHS100 Alcon, Fort Worth, TX, PHS101 PHS102 PHS103 PHS104 Graduate & Professional Student Government, The University of Iowa, Iowa City, IA, PHS105 Sygeny Ltd., Helsinki, Finland PHS106 PHS107 California Worker's Comp, Sacramento, CA, PHS108 PHS109 Janssen Scientifi c Affairs, LLC (Johnson & Johnson), Titusville, NJ,

7 A390 VALUE IN HEALTH 20 (2017) A384 A397 PHS11 PHS110 PHS111 PHS112 PHS113 PHS114 PHS115 PHS116 PHS117 PHS118 PHS119 PHS12 PHS120 PHS121 PHS122 PHS123 PHS124 PHS125 PHS126 PHS127 PHS128 PHS129 PHS13 PHS130 PHS131 PHS132 PHS133 PHS134 PHS135 PHS136 PHS137 PHS138 PHS139 PHS14 PHS140 PHS141 PHS142 PHS143 PHS144 PHS145 PHS146 PHS147 PHS148 PHS149 PHS15 PHS150 PHS151 PHS152 PHS153 PHS154 PHS155 PHS156 PHS157 PHS158 PHS159 PHS16 PHS160 PHS161 PHS162 PHS163 PHS164 PHS165 PHS166 PHS167 PHS168 PHS169 PHS17 PHS170 PHS171 PHS172 PHS173 PHS174 PHS175 PHS176 PHS177 PHS178 PHS179 PHS18 PHS180 PHS181 PHS182 PHS183 PHS184 MUTUAL SER EPS, Cartage, Colombia Suramericana de Seguros, Medellin, Colombia Health Care in Canada Survey, Montreal, QC, Canada Novartis Farma SpA, Origgio, Italy Walgreen Co., Deerfi eld, IL, Sygeny Ltd., Helsinki, Finland MUTUAL SER EPS, Cartage, Colombia Ministry of Science and Technology, Taipei, Taiwan University of South Caroli Colombia, SC, National Institutes of Health, Washington, DC, Local Health Authority of Parma, Parma, Italy MUTUAL SER EPS, Cartage, Colombia Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore Costello Medical Consulting, Cambridge, UK Keystone First, Philadelphia, PA, Beatrice Hunter Cancer Research Institute, Halifax, NS, Canada Australian Research Council Centre of Excellence in Population Ageing Research (CEPAR), Sydney, Australia The Israel National Institute for Health Policy Research (NIHP), Tel Hashomer, Israel Medica research Institute, Minneapolis, MN, Coomeva EPS, Cali, Colombia Coosalud EPS, Cartage, Colombia Komoto Family Foundation, Bakersfi eld, CA, Edwards Lifescience, Irvine, CA, Janssen Scientifi c Affairs, LLC, Titusville, NJ, Albert Einstein Hospital, São Paulo, Brazil Hospital Albert Einstein, São Paulo, Brazil Sage Therapeutics, Inc., Cambridge, MA, Optum, Minnetonka, MN, Sanofi, Moscow, Russia University of Utah Program in Personalized Health, Salt Lake City, UT, Biogen, Weston, MA, Novartis Healthcare Phil., Inc., Makati, Philippines Sage Therapeutics, Inc., Cambridge, MA, Clinica Maternidad Rafael Calvo C, Cartage, Colombia Johnson and Johnson, New Brunswick, NJ, Ministry of Education, Tokyo, Japan Ministry of Education, Tokyo, Japan Renal Therapy System, Bogota, Colombia Healthcore Inc., Wilmington, DE, Ministry of Education, Tokyo, Japan Healthcore Inc., Wilmington, DE, ROCHE, Bogota D.C., Colombia PHS185 PHS186 PHS187 PHS188 Young Research COLCIENCIAS (2015), Bogotá, Colombia PHS189 PHS19 MUTUAL SER EPS, Cartage, Colombia PHS190 Renal Therapy Services, Bogotá, Colombia PHS191 PHS192 PHS193 PHS194 PHS195 PHS196 PHS197 PHS198 PHS199 PHS2 PHS20 Sage Therapeutics, Inc., Cambridge, MA, PHS200 PHS201 PHS202 Shanghai Medical Information Center, Shanghai, China PHS203 PHS204 AstraZeneca, Luton, UK PHS205 PHS206 PHS207 PHS208 Bristol-Myers Squibb, Princeton, NJ, PHS21 MUTUAL SER EPS, Cartage, Colombia PHS22 Sage Therapeutics, Inc., Cambridge, MA, PHS23 Cuenta de Alto Costo, Bogota, Colombia; Novo Nordisk, Bogota, Colombia PHS24 PHS25 PHS26 MUTUAL SER EPS, Cartage, Colombia PHS27 MUTUAL SER EPS, CART, Colombia PHS28 The Nicholson Foundation, Newark, NJ, PHS29 PHS3 Seattle Genetics, Bothell, WA, PHS30 PHS31 National Evidence-based Healthcare Collaborating Agency, Seoul, South Korea PHS32 PHS33 PHS34 PHS35 UCare, Minneapolis, MN, ; Blue Cross Blue Shield of Minnesota, Eagan, MN, ; Care Providers of Minnesota, Bloomington, MN, PHS36 PHS37 PHS38 PHS39 AstraZeneca, Gaithersburg, MD, PHS4 PHS40 PHS41 PHS42 DSI, Edison, NJ, PHS43 PHS44 MUTUAL SER EPS, Cartagena, Colombia PHS45 MUTUAL SER EPS, Cartagena Colombia PHS46 PHS47 Mutual Ser EPS, Cartagena, Colombia PHS48 PHS49 PHS5 PHS50 Mutual Ser EPS, Cartagena, Colombia PHS51 InnFocus Inc., Miami, FL, PHS52 PHS53 Millennium Pharmaceuticals, Cambridge, MA, PHS54 Mutual Ser, Cartagena, Colombia PHS55 Fundação de Amparo à Pesquisa do Estado de Goiás, Goiania, Brazil PHS56 Mutual Ser EPS, Cartagena, Colombia PHS57 Sanofi Chi Shanghai, China PHS58 Otsuka Pharmaceutical Development & Commercialization, Rockville, MD, PHS59 Shire, Lexington, MA, PHS6 mystrength, Inc., Denver, CO, PHS60 PHS61 Colciencias, Bogota, Colombia PHS62 PHS63 PHS64 Amgen Inc., Thousand Oaks, CA, PHS65 Bristol-Myers Squibb, Princeton, NJ, PHS66 Hospital Albert Einstein, São Paulo, Brazil PHS67 Alberta Health Services, Edmonton, AB, Canada PHS68 PHS69 PHS7 MUTUAL SER EPS, Cartagena, Colombia

8 VALUE IN HEALTH 20 (2017) A384 A397 A391 PHS70 PHS71 PHS72 PHS73 PHS74 PHS75 PHS76 PHS77 PHS78 PHS79 PHS8 PHS80 PHS81 PHS82 PHS83 PHS84 PHS85 PHS86 PHS87 PHS88 PHS89 PHS9 PHS90 PHS91 PHS92 PHS93 PHS94 PHS95 PHS96 PHS97 PHS98 PHS99 PIH1 PIH10 PIH11 PIH12 PIH13 PIH14 PIH15 PIH16 PIH17 PIH18 PIH19 PIH2 PIH20 PIH21 PIH22 PIH23 PIH24 PIH25 PIH26 PIH27 PIH28 PIH29 PIH3 PIH30 PIH31 PIH32 PIH33 PIH34 PIH35 PIH36 PIH37 PIH38 PIH39 PIH4 PIH40 PIH41 PIH42 PIH43 PIH44 PIH45 PIH46 PIH47 PIH48 PIH49 PIH5 PIH50 PIH51 PIH52 PIH53 PIH54 PIH6 PIH7 Medtronic PLC, Minneapolis, MN, Janssen Scientifi c Affairs, LLC, Horsham, PA, Bristol-Myers Squibb, Princeton, NJ, Gilead Sciences Canada, Mississauga, ON, Canada Allergan plc, Dublin, Ireland Gilead Sciences Canada, Mississauga, ON, Canada Putnam, Boston, MA, Vertex Pharmaceuticals Incorporated, Boston, MA, Bayer Healthcare, Loos, France Sonderegger Research Center for the Dissertator Research Grant, Madison, WI, MUTUAL SER EPS, Cartagena, Colombia University of Gondar, Gondar, Ethiopia National Institute for Health Research, UK Jayne Koskinas Ted Giovanis Foundation for Health and Policy, Highland, MD, Agency for Healthcare Research and Quality, Rockville, MD, CIHR, Ottawa, ON, Canada Biogen, Weston, MA, MSD Brasil, Sao Paulo, Brazil BAXTER, Bogota, Colombia Abbott Nutrition, Columbus, OH, MSD Brasil, Sao Paulo, Brazil Abbott Nutrition, Columbus, OH, AbbVie, Chicago, IL, Bayer, Bogota, Colombia MSD Brasil, Sao Paulo, Brazil Australian Research Council Centre of Excellence in Population Ageing Research (CEPAR), Sydney, Australia Grunenthal GmbH, Aachen, Germany National Health Research Institutes, Miaoli County, Taiwan Abbott Nutrition, Chicago, IL, Medtronic, Mansfi eld, MA, AmeriHealth Caritas, Philadelphia, PA, Abbott Nutrition, Columbus, OH, Merck & Co., Inc., Kenilworth, NJ, AbbVie Inc., North Chicago, IL, Hologic, Inc., Marlborough, MA, Pfi zer, New York, NY, Instituto Nacional de Salud, Bogotá, Colombia PIH8 Otsuka Pharmaceutical Development & Commercialization, Rockville, MD, PIH9 PIN1 PIN10 Optum, Eden Prairie, MN, PIN11 PIN12 PIN13 PIN14 GSK, Philadelphia, PA, PIN15 Merck & Co., Inc., Kenilworth, NJ, PIN16 PIN17 PIN18 PIN19 Sanofi Pasteur, Washington, DC, PIN2 PIN20 PIN21 Pfi zer Investment Co. Ltd., Beijing, China PIN22 PIN23 PIN24 PIN25 Food and Health Bureau, Hong Kong, Hong Kong PIN26 PIN27 Sanofi -Pasteur, Bogota, Colombia PIN28 PIN29 AstraZeneca, Cotia, Brazil PIN3 Boston Strategic Partners, Boston, MA, PIN30 Astra, Cotia, Brazil PIN31 PIN32 Korea Centers for Disease Control and Prevention, Osong, South Korea PIN33 Alexander von Humboldt Foundation, Bonn, Germany PIN34 PIN35 PIN36 Merck & Co., Inc., Kenilworth, NJ, PIN37 PIN38 PIN39 Broad Green Clinic, Bamenda, Cameroon PIN4 Boston Strategic Partners, Boston, MA, PIN40 PIN41 Gilead Sciences, Inc., Foster City, CA, PIN42 PIN43 Neem Biotech, Abertillery, UK PIN44 Janssen, Mexico City, Mexico PIN45 PIN46 The Medicines Company, Parsippany, NJ, PIN47 GlaxoSmithKline Biologicals SA, Philadelphia, PA, PIN48 PIN49 PIN5 PIN50 Sanofi Pasteur, Lyon, France PIN51 Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, MD, ; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, PIN52 Genocea, Cambridge, MA, PIN53 U. S. Food and Drug Administration, Silver Spring, MD, PIN54 Bristol-Myers Squibb, Shanghai, China PIN55 Salud Total EPS, Bogotá D.C., Colombia PIN56 PIN57 PIN58 PIN59 PIN6 Boston Strategic Partners, Boston, MA, PIN60 PIN61 MSD K.K., Tokyo, Japan PIN62 PIN63 PIN64 PIN65 Ipsos, New York, NY, PIN66 Universiti Sains Malaysia, Penang, Malaysia PIN67 Universiti Sains Malaysia, Penang, Malaysia PIN68 PIN69 PIN7 Boston Strategic Partners, Boston, MA, PIN70 PIN71 PIN72 PIN73 PIN74 PIN75 PIN76 PIN77 PIN78 PIN79 PIN8 PIN80 PIN81 Merck & Co., Inc., Kenilworth, NJ,

9 A392 VALUE IN HEALTH 20 (2017) A384 A397 PIN82 PIN83 PIN84 PIN85 PIN86 PIN87 PIN9 PM1 PM2 PM3 PM4 PMD1 PMD10 PMD100 PMD101 PMD102 PMD103 PMD104 PMD105 PMD106 PMD107 PMD108 PMD109 PMD11 PMD110 PMD111 PMD112 PMD113 PMD114 PMD115 PMD116 PMD117 PMD118 PMD119 PMD12 PMD120 PMD121 PMD122 PMD123 PMD124 PMD125 PMD13 PMD14 PMD15 PMD16 PMD17 PMD18 PMD19 PMD2 PMD20 PMD21 PMD22 PMD23 PMD24 PMD25 PMD26 PMD27 PMD28 PMD29 PMD3 PMD30 PMD31 PMD32 PMD33 PMD34 PMD35 PMD36 PMD37 PMD38 PMD39 PMD4 PMD40 PMD41 PMD42 PMD43 PMD44 PMD45 PMD46 PMD47 PMD48 PMD49 Merck & Co., Inc., Kenilworth, NJ, Cepheid, Sunnyvale, CA, AbbVie Inc., Saint-Laurent, QC, Canada National Institutes of Health, Rockville, MD, Bayer Pharmaceuticals, Whippany, NJ, Optum, Eden Prairie, MN, National Institute for Health Research, England, UK AcelRx Pharmaceuticals, Inc., Redwood City, CA, National Institutes of Health, Bethesda, MD, Ethicon Inc., Somerville, NJ, Instituto Nacional de Salud, Bogotá, D.C, Colombia; Hospital Universitario Federico Lleras Acosta, Bogotá, D.C., Colombia Independence Blue Cross, Philadelphia, PA, Johnson and Johnson, New Brunswick, NJ, Helsinn Healthcare, Lugano, Switzerland Johnson & Johnson, New Brunswick, NJ, Johnson and Johnson Medical Chi Shanghai, China United States Food and Drug Administration, Silver Spring, MD, Edwards Lifesciences, Irvine, CA, NIHR Research for Patient Benefi t Programme, London, UK National Evidence based Healthcare Collaborating Agency, Seoul, South Korea BAXTER, Bogota, Colombia Ministry of Science and Technology, Taipei, Taiwan; Center for Drug Evaluation, Taipei, Taiwan Newcastle University and the Health Foundation, Newcastle upon Tyne, UK AcelRx Pharmaceuticals, Inc., Redwood City, CA, National Institute for Health Research Manchester Musculoskeletal Biomedical Research Unit Studentship, Manchester, UK Johnson & Johnson, New Brunswick, NJ, Boston scientifi c, Shanghai, China Johnson and Johnson Medical Chi Shanghai, China U.S Food and Drug Administration, Silver Spring, MD, Decision Resources Group, Burlington, MA, Johnson & Johnson Medical, Mexico City, Mexico Health Quality Ontario, Toronto, ON, Canada Astrazeneca, Bogota, CO, Colombia Thermo Fisher Scientifi c, Waltham, MA, BIOTRONIK Comercial Médica Ltd.a., Sao Paulo, Brazil Medtronic, Duluth, GA, Aesculap Inc., Center Valley, PA, Tecnoquimicas, Cali, Colombia C.R. Bard Inc., Murray Hill, NJ, Dexcom, Inc., San Diego, CA, Telefl ex, Morrisville, NC, Circassia Pharmaceuticals, Morrisville, NC, Valeritas, Bridgewater, NJ, Circassia Pharmaceuticals, Morrisville, NC, Health Quality Ontario, Toronto, ON, Canada Commonwealth Diagnostic International, Salem, MA, Ethicon Inc., Somerville, NJ, C.R. Bard, Inc., Murray Hill, NJ, Valeritas, Bridgewater, NJ, Ministry of Health and Welfare, Seoul, South Korea Materialise NV, Leuven, Belgium Cardiovascular Systems, Inc., St. Paul, MN, BARD ACCESS SYSTEMS, Salt Lake City, UT, Hologic, Inc., Marlboro, MA, Boston Scientifi c Corp., Marlborough, MA, Medtronic, INC., Minneapolis, MN, Quest Medical, Inc., Allen, TX, Medical University-Sofi a, Sofia, Bulgaria HeartFlow, Redwood City, CA, PMD5 PMD50 PMD51 PMD52 PMD53 Bayer Yakuhin Ltd., Tokyo, Japan PMD54 SIRO Clinpharm Pvt Ltd., Thane, India PMD55 Abbott Diabetes Care, Alameda, CA, PMD56 PMD57 Dexcom, Inc., San Diego, CA, PMD58 PMD59 PMD6 Univesiti Sains Malaysia, Penang, Malaysia PMD60 Abbott Diabetes Care, Alameda, CA, PMD61 BIOTRONIK Comercial Médica Ltd.a., Sao Paulo, Brazil PMD62 PMD63 PMD64 Johnson & Johnson Medical (China) Ltd., Shanghai, China PMD65 PMD66 National Science Foundation, Beijing, China PMD67 PMD68 Veracyte, Inc., South San Francisco, CA, PMD69 PMD7 PMD70 PMD71 PMD72 Health Quality Ontario, Toronto, ON, Canada PMD73 Health Quality Ontario, Toronto, ON, Canada PMD74 Costello Medical Consulting Ltd., Cambridge, UK PMD75 Medtronic PLC, Minneapolis, MN, PMD76 Johnson and Johnson Medical, Beijing, China PMD77 PMD78 Center for Health Economics and Policy Studies, Depok, Indonesia PMD79 Edwards Lifesciences, Nyon, Switzerland PMD8 PMD80 Boston Scientifi c Corp., Marlborough, MA, PMD81 PMD82 Abbott Laboratories, Alameda, CA, PMD83 Merck & Co., Inc., North Wales, PA, PMD84 Lenstec, Inc., St, Petersburg, FL, PMD85 PMD86 PMD87 PMD88 Thermo Fisher Scientifi c, Portage, MI, PMD89 Hologic, Inc., Marlborough, MA, PMD9 Cancer Prevention Research Institute of Texas, Austin, TX, PMD90 Hologic, Inc., Marlborough, MA, PMD91 European Health Technology Institute for Socio-Economic Research (EHTI), Bruxelles, Belgium PMD92 PMD93 Ministry of Health, Rome, Italy PMD94 PMD95 Xcenda, AmerisourceBergen, Palm Harbor, FL, PMD96 Edwards Lifesciences, Irvine, CA, PMD97 Bard Ltd., Crawley, UK PMD98 Medtronic PLC, Minneapolis, MN, PMD99 PMH1 PMH10 Lundbeck Canada, Montreal, QC, Canada PMH11 Lundbeck Canada, Montreal, QC, Canada PMH12 Sage Therapeutics, Inc., Cambridge, MA, PMH13 Agency for Healthcare Research and Quality, Rockville, MD, PMH14 PMH15 PMH16 PMH17 PMH18 PMH19 University of Texas, Austin, TX, PMH2 PMH20 Princeton, NJ, PMH21 PMH22 PMH23 Princeton, NJ, PMH24 Sunovion Pharmaceuticals, Inc., Marlborough, MA, PMH25 Janssen Scientifi c Affairs, Titusville, NJ, PMH26 PMH27 Janssen Scientifi c Affairs, LLC, Titusville, NJ, PMH28 Lundbeck (Beijing) Pharmaceutical Consulting Co, Beijing, China PMH29 PMH3 PMH30 Janssen, Raritan, NJ, PMH31 PMH32 Republic of Kazakhstan Ministry of Science and Education, Asta Kazakhstan PMH33 Swedish Research Council, Stockholm, Sweden

10 VALUE IN HEALTH 20 (2017) A384 A397 A393 PMH34 PMH35 PMH36 PMH37 PMH38 PMH39 PMH4 PMH40 PMH41 PMH42 PMH43 PMH44 PMH45 PMH46 PMH47 PMH48 PMH49 PMH5 PMH50 PMH51 PMH52 PMH53 PMH54 PMH55 PMH56 PMH57 PMH58 PMH59 PMH6 PMH60 PMH61 PMH62 PMH63 PMH64 PMH65 PMH66 PMH67 PMH68 PMH69 PMH7 PMH70 PMH71 PMH72 PMH73 PMH74 PMH75 PMH8 PMH9 PMS1 PMS10 PMS11 PMS12 PMS13 PMS14 PMS15 PMS16 PMS17 PMS18 PMS19 PMS2 PMS20 PMS21 PMS22 PMS23 PMS24 Takeda Pharmaceuticals U.S.A., Inc., Deerfi eld, IL, ; Lundbeck LLC, Deerfi eld, IL, Janssen GCC, Dubai, United Arab Emirates; Janssen Pharmaceutica NV, Beerse, Belgium Princeton, NJ, Indivior Inc., Richmond, VA, Princeton, NJ, Abbott Nutrition, Chicago, IL, Indivior Inc., Richmond, VA, National Institutes of General Medical Sciences, Bethesda, MD, ; Claude Worthington Benedum Foundation, Pittsburgh, PA, Conselho Nacional de Desenvolvimento Científi co e Tecnológico (CNPq), Belo Horizonte, Brazil; Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG), Belo Horizonte, Brazil; Centro Colaborador do SUS (CCATES), Belo Horizonte, Brazil Otsuka Pharmaceuticals, Princeton, NJ, Princeton, NJ, ; Lundbeck Pharmaceuticals Services, LLC, Deerfield, IL, Otsuka Pharmaceuticals, Princeton, NJ, Otsuka Pharmaceuticals, Princeton, NJ, Otsuka Pharmaceuticals, Princeton, NJ, Princeton, NJ, ; Lundbeck Pharmaceuticals Services, LLC, Deerfield, IL, The Cigna Companies, Bloomfi eld, CT, Centers for Disease Control and Prevention, Atlanta, GA, Princeton, NJ, ; Lundbeck Pharmaceuticals Services, LLC, Deerfield, IL, Princeton, NJ, ; Lundbeck Pharmaceuticals Services, LLC, Deerfield, IL, Soberlink, Huntington Beach, CA, Braeburn Pharmaceuticals, Princeton, NJ, ; Camurus AB, Lund, Sweden Janssen Scientifi c Affairs, Titusville, NJ, Burapha University, Cholburi, Thailand Eli Lilly Japan, Kobe, Japan Princeton, NJ, Lundbeck SAS, Issy-les-Moulineaux, France BIOMAB IPS, Bogota, Colombia; ALZAK Foundation, Cartagena, Colombia Lilly Suzhou Pharmaceutical Co. Ltd., Shanghai, China Biogen International GmbH, Zug, Switzerland Merck, shanghai, China Bristol-Myers Squibb, Princeton, NJ, Pfi zer Ltd., New Taipei City, Taiwan PMS25 PMS26 PMS27 PMS28 PMS29 PMS3 PMS30 PMS31 PMS32 PMS33 PMS34 PMS35 PMS36 PMS37 PMS38 PMS39 PMS4 PMS40 PMS41 PMS42 PMS43 PMS44 PMS45 PMS46 PMS47 PMS48 PMS49 PMS5 PMS50 PMS51 PMS52 PMS53 PMS54 PMS55 PMS56 PMS57 PMS58 PMS59 PMS6 PMS60 PMS61 PMS62 PMS63 PMS64 PMS65 PMS66 PMS67 PMS68 PMS69 PMS7 PMS70 PMS71 PMS72 PMS73 PMS74 PMS75 PMS76 PMS77 PMS78 PMS79 PMS8 PMS80 PMS81 PMS82 PMS9 PND1 PND10 PND11 PND12 PND13 PND14 PND15 PND16 PND17 PND18 PND19 PND2 PND20 PND21 Advera Health Analytics, Inc., Santa Rosa, CA, ; WEA Trust, Madison, WI, Novartis Pharma AG, Basel, Switzerland Flexion Therapeutics, Burlington, MA, F. Hoffmann La Roche, Basel, Switzerland Amgen, Thousand Oaks, CA, Ministerio de salud y seguridad social, Bogotá, Colombia Ceterix Orthopaedics, Inc., Fremont, CA, China Traditional Chinese Medicine Co. Limited, Foshan, China Amgen Korea, Seoul, South Korea Samumed, San Diego, CA, Skaggs Foundation, Salt Lake City, UT, AbbVie, North Chicago, IL, King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia Janssen Research & Development, LLC, Spring House, PA, ; GlaxoSmithKline, Collegeville, PA, Janssen Scientifi c Affairs, LLC, Horsham, PA, GlaxoSmithKline, Durham, NC, Janssen Research & Development, LLC, Spring House, PA, ; GlaxoSmithKline, Collegeville, PA, Novartis Pharmaceuticals Corporation, East Hanover, NJ, Novartis Pharmaceuticals Corporation, East Hanover, NJ, GlaxoSmithKline, Collegeville, PA, ; Janssen Research & Development, LLC, Spring House, PA, Janssen, Spring House, PA, Amgen, Seoul, South Korea Janssen Research & Development, LLC, Spring House, PA, ; GlaxoSmithKline, Collegeville, PA, Ironwood Pharma, Cambridge, MA, QuintilesIMS, New York, NY, GlaxoSmithKline, Durham, NC, Eli Lilly & Company, Indianapolis, IN, Institute for Clinical and Economic Review, Boston, MA, MT Pharma America, Inc., Jersey City, NJ, Neurocrine Biosciences, Inc., San Diego, CA, EMD Serono, Inc. (a business of Merck KGaA, Darmstadt, Germany), Rockland, MA, Patient Centered Outcomes Research Institute, Washington DC, DC, ; National Institutes of Health, Bethesda, MD, Institute of Clinical and Economic Review, Boston, MA, Sage Therapeutics, Cambridge, MA, Biogen, Cambridge, MA, Genentech, Inc., South San Francisco, CA, RLS foundation, Austin, TX, Lundbeck, Deerfi eld, IL,

11 A394 VALUE IN HEALTH 20 (2017) A384 A397 PND22 PND23 PND24 PND25 PND26 PND27 PND28 PND29 PND3 PND30 PND31 PND32 PND33 PND34 PND35 PND36 PND37 PND38 PND39 PND4 PND40 PND41 PND42 PND43 PND44 PND45 PND46 PND47 PND48 PND49 PND5 PND50 PND51 PND52 PND53 PND54 PND55 PND56 PND57 PND58 PND59 PND6 PND60 PND61 PND62 PND63 PND64 PND65 PND66 PND7 PND8 PND9 PP1 PP2 PP3 PP4 PR1 PR2 PR3 PR4 PRM1 PRM10 PRM100 PRM101 PRM102 PRM103 PRM104 PRM105 PRM106 PRM107 PRM108 PRM109 PRM11 PRM110 PRM111 PRM112 PRM113 PRM114 PRM115 Lundbeck, Deerfi eld, IL, Genentech, Inc., South San Francisco, CA, Biogen, Cambridge, MA, Biogen, Cambridge, MA, Otsuka, Deerfi eld, IL, Richter-Gedeon Nyrt, Budapest, Hungary; KTIA-NAP (Hungarian Brain Research Program), Budapest, Hungary Sanofi, Cambridge, MA, Biogen Idec, Cambridge, MA, Biogen Idec, Cambridge, MA, Princeton, NJ, Axovant Sciences, Inc., New York, NY, Evidera, Bethesda, MD, AbbVie, North Chicago, IL, Amgen, Thousand Oaks, CA, Biogen, Cambridge, MA, Adamas Pharmaceuticals, Emeryville, CA, CareMed Specialty Pharmacy, Lake Success, NY, UCSF- Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, ; UCSF Mount Zion Health Fund, San Francisco, CA, MKTXS, Raritan, NJ, International Consortium to Advance Clinical Trials for Prader-Willi Syndrome (PWS-CTC), Walnut, CA, CIHR, Ottawa, ON, Canada; Genome Canada, Ottawa, ON, Canada Biogen, Cambridge, MA, InTask Inc., Morristown, NJ, Axovant Sciences, Inc., New York, NY, Lundbeck (Beijing) Pharmaceutical Consulting Co, Beijing, China NIH, Bethesda, MD, ACADIA Pharmaceuticals Inc., San Diego, CA, Novartis Pharmaceuticals, East Hanover, NJ, NIH/The National Human Genome Research Institute (NHGRI), Bethesda, MD, Teva Pharmaceutical Industries, Petach Tikva, Israel Novartis Pharmaceutical Corporation, East Hanover, NJ, Sunovion Pharmaceuticals Inc., Marlborough, MA, Sage Therapeutics, Inc., Cambridge, MA, Marshall B. Ketchum University, Fullerton, CA, Merck & Co., Inc., Kenilworth, NJ, NORFACE Welfare State Futures Programme (22119), Berlin, Germany; Austrian Science Fund (FWF), Vien, Austria PCORI, N/A, DC, Janssen Pharmaceuticals of Johnson & Johnson, Beerse, Belgium Novartis, East Hanover, NJ, Decision Resources Group, Burlington, MA, Bristol-Myers Squibb, Princeton, NJ, MKTXS, Raritan, NJ, Amgen Inc., Thousand Oaks, CA, SFI, Limerick, Ireland; HRB, Limerick, Ireland China Medical Board, Cambridge, MA, Glaucoma Research Society of Canada, Toronto, ON, Canada Alnylam Pharmaceuticals, Cambridge, MA, Ultragenyx, San Francisco, CA, Pfi zer, Inc., New York, NY, Bristol-Myers-Squibb, Princeton, NJ, Novartis Pharma AG, Basel, Switzerland ERT, Boston, MA, PRM116 PRM117 PRM118 PRM119 PRM12 PRM120 PRM121 PRM122 PRM123 PRM124 PRM125 PRM126 PRM127 PRM128 PRM129 PRM13 PRM130 PRM131 PRM132 PRM133 PRM134 PRM135 PRM136 PRM137 PRM138 PRM139 PRM14 PRM140 PRM141 PRM142 PRM143 PRM144 PRM145 PRM146 PRM147 PRM148 PRM149 PRM15 PRM150 PRM151 PRM152 PRM153 PRM154 PRM155 PRM156 PRM157 PRM158 PRM159 PRM16 PRM160 PRM161 PRM162 PRM163 PRM164 PRM165 PRM166 PRM167 PRM168 PRM169 PRM17 PRM170 PRM171 PRM172 PRM173 PRM174 PRM175 PRM176 PRM177 PRM178 PRM179 PRM18 PRM180 PRM181 Austrian Science Fund (FWF), Vien Austria; NORFACE Welfare State Futures programme (grant number 22119), Berlin, Germany Genentech, South San Francisco, CA, National Institute of Health Research HTA Programme, London, UK Ultragenyx, Novato, CA, Kantar Health, New York, NY, EuroQol Research Foundation, Rotterdam, Netherlands ERT, Boston, MA, Gedeon Richter Plc, Budapest, Hungary GSK, Brussels, Belgium Genentech, Inc., South San Francisco, CA, Mapi Research Trust, Lyon, France Corporate Translations Inc., East Hartford, CT, National Natural Science Foundation, Beijing, China; Chinese Humane Social Science Fund Project of Ministry of Education, Beijing, China; Chinese National Social Science Foundation, Beijing, China Allergan Sales, LLC, Parsippany, NJ, ; Collegium Pharmaceutical, Inc., Canton, MA, ; Depomed, Inc., Newark, CA, ; Endo Pharmaceuticals, Inc., Malvern, PA, ; Janssen Pharmaceuticals, Inc., Titusville, NJ, ; MallInc.krodt, Inc., Hazelwood, MO, ; Pernix Therapeutics Holdings, Inc., Morristown, NJ, ; Pfizer, Inc., New York, N Blueprint Medicines, Cambridge, MA, Mapi Research Trust, Lyon, France Novo Nordisk Inc., Plainsboro, NJ, Bracket, Wayne, PA, Ironwood Pharmaceuticals, Cambridge, MA, ; Allergan, Parsippany, NJ, ; Sol Gel Technologies, Ness Zio Israel National Institute on Minority Health and Health Disparities, Bethesda, MD, Ironwood Pharmaceuticals, Inc., Cambridge, MA, ; Allergan, PLC, Jersey City, NJ, Incyte, Wilmington, DE, Avalere - An Inovalon Company, Bowie, MD, Novartis Pharma AG, Basel, Switzerland Merrimack Pharmaceuticals, Cambridge, MA, National Institute for Health and Care Excellence Decision Support Unit (NICE DSU), London, UK Novartis Pharma AG, Basel, Switzerland AstraZeneca, Wilmington, DE, ISPOR, Lawrenceville, NJ, Ethicon, Inc., Somerville, NJ, UCB Pharma, Brussels, Belgium Eisai Inc., Woodcliff Lake, NJ, QuintilesIMS, Boulogne Billancourt, France Evidera, St-Laurent, QC, Canada Mapi Research Trust, Lyon, France ICON plc, Vancouver, BC, Canada Shire, Cambridge, MA, Bioventus, Durham, NC, Mapi Research Trust, Lyon, France

12 VALUE IN HEALTH 20 (2017) A384 A397 A395 PRM182 F. Hoffmann- La Roche, Basel, Switzerland PRM183 Janssen, Washington, DC, ; Astellas, Northbrook, IL, ; Eli Lilly, Indianapolis, IN, ; Genentech, San Francisco, CA, ; Pfi zer, New York, NY, ; Sanofi, Bridgewater Township, NJ, ; UCB Biopharma, Brussels, Belgium; National Pharmaceutical Council, Washington, DC, PRM184 PRM185 PRM186 PRM187 PRM188 PRM189 PRM19 PhRMA, Washington DC, DC, PRM190 CR Bard Inc., Murray Hill, NJ, PRM191 Nestle Health Science, Florham Park, NJ, PRM192 PRM193 PRM194 Innovative Medicines Initiative, Brussels, Belgium; NICE, Manchester, UK PRM195 PRM2 Optum, Eden Prairie, MN, PRM20 NIHR, London, UK PRM21 GetReal European Consortium, London, UK PRM22 ICON plc, Dublin, Ireland PRM23 ICON plc, Dublin, Ireland PRM24 PRM25 PRM26 PRM27 PRM28 shanghai centennial co. Ltd., shanghai, China PRM29 PRM3 Amgen Inc., Thousand Oaks, CA, PRM30 Ontario Ministry of Health & Long-Term Care, -, ON, Canada; Canadian Health Services Research Foundation and Offi ce of Nursing Policy, Health Canada, Canada; Canadian Institutes of Health Research, Canada PRM31 PRM32 Samumed, San Diego, CA, PRM33 PRM34 Universidad de Cartage Cartagena, Colombia PRM35 PRM36 PRM37 Jassen Pharmaceuticals Inc., Titusville, NJ, PRM38 PRM39 Ministry of Health, Rome, Italy PRM4 PRM40 AstraZeneca, Wilmington, DE, PRM41 PRM42 PRM43 Novartis Pharma AG, Basel, Switzerland PRM44 AMGEN, Rockville, MD, ; Ambry Genetics, Aliso Viejo, CA, ; Biocept, San Diego, CA, ; Caris Lifesciences, Irving, TX, ; Foundation Medicine, Cambridge, MA, ; Genentech, South San Francisco, CA, ; Genomic Health, Redwood City, CA, ; Merck & Co., Kenilworth, NJ, ; Natera, San Carlos, CA, ; Qiagen, Hilden, German PRM45 MT Pharma America, Inc., Jersey City, NJ, PRM46 PRM47 Lundbeck LLC, Chicago, IL, PRM48 PRM49 PRM5 Neurocrine Biosciences, Inc., San Diego, CA, PRM50 PRM51 PRM52 Novartis Pharmaceuticals Corporation, East Hanover, NJ, PRM53 Harvard T.H. Chan School of Public, Boston, MA, PRM54 inventiv Health, Manchester, MA, PRM55 PRM56 Sanofi Genzyme, Cambridge, MA, PRM57 QuintilesIMS, Sao Paulo, Brazil PRM58 PRM59 PRM6 Teva Branded Pharmaceutical Products R&D, Inc., Frazer, PA, PRM60 PRM61 PRM62 PRM63 Kantar Health, New York, NY, PRM64 PRM65 PRM66 PRM67 AHRQ, Washington, DC, PRM68 PRM69 PRM7 PRM70 PRM71 Axovant Sciences, New York, NY, PRM72 PRM73 PRM74 PRM75 PRM76 PRM77 PRM78 PRM79 PRM8 PRM80 PRM81 PRM82 PRM83 PRM84 PRM85 PRM86 PRM87 PRM88 PRM89 PRM9 PRM90 PRM91 PRM92 PRM93 PRM94 PRM95 PRM96 PRM97 PRM98 PRM99 PRS1 PRS10 PRS11 PRS12 PRS13 PRS14 PRS15 PRS16 PRS17 PRS18 PRS19 PRS2 PRS20 PRS21 PRS22 PRS23 PRS24 PRS25 PRS26 PRS27 PRS28 PRS29 PRS3 PRS30 PRS31 PRS32 PRS33 PRS34 PRS35 PRS36 PRS37 PRS38 PRS39 PRS4 PRS40 PRS41 PRS42 PRS43 PRS44 PRS45 PRS46 PRS5 PRS6 PRS7 PRS8 PRS9 PSS1 PSS10 PSS11 PSS12 PSS13 PSS14 PSS15 PSS16 Sanofi U.S., Inc., Bridgewater, NJ, Janssen Scientifi c Affairs, LLC, Horsham, PA, National Cancer Institute, Bethesda, MD, F. Hoffmann La-Roche Ltd., Basel, Switzerland U.S. Centers for Disease Control and Prevention, Atlanta, GA, Merck & Co. Inc., Kenilworth, NJ, Janssen pharmaceuticals Inc., New Brunswick, NJ, Merck & Co., Inc., Kenilworth, NJ, Novartis, East Hanover, NJ, IBM, Cleveland, OH, Amarin Pharma, Bedminister, NJ, PatientsLikeMe, Cambridge, MA, Evidera, London, Ukraine National Institute for Health Research, Leeds, UK Teva Pharmaceuticals, Frazer, PA, GlaxoSmithKline, Bogotá, Colombia International Training and Research in Environmental and Occupational Health (# 3D43TW S1) from the Fogarty International Centre at the National Institute of Health, Bethesda, MD, NOVARTIS, Mexico City, Mexico GlaxoSmithKline, RTP, NC, AstraZeneca, Cotia, Brazil AstraZeneca, Cotia, Brazil Sunovion Pharmaceuticals Inc., Waterford, MA, AstraZeneca UK Limited, Cambridge, UK Coosalud EPS, Cartagena, Colombia Pfi zer, Hong Kong, Hong Kong MKTXS, Raritan, NJ, Sunovion Pharmaceuticals Inc., Marlborough, MA, GSK, Brentford, UK GlaxoSmithKline Consumer Healthcare, Warren, NJ, Sunovion Pharmaceuticals, Inc., Marlborough, MA, Novartis Pharmaceuticals Corporation, East Hanover, NJ, Novartis Pharmaceuticals Corporation, East Hanover, NJ, Paratek Pharmaceuticals, King of Prussia, PA, Paratek Pharmaceuticals, King of Prussia, PA, Tsinghua University, Beijing, China Therakos Inc., a MallInc.krodt Corporation, London, UK Novartis Pharmaceuticals, East Hanover, NJ, Alimera, Berlin, Germany Novartis Pharma AG, Basel, Switzerland Daewoong pharmaceuticals, Seoul, South Korea Novartis Pharma AG, Basel, Switzerland Allergan CIS SARL, Moscow, Russia