Computations in the Brain and Translational Neuroscience

Transcription

1 1 st Baltic-Nordic Summer School on Neuroinformatics Computations in the Brain and Translational Neuroscience PROGRAM AND ABSTRACT BOOK May 29-31, 2013 Vytautas Magnus University Kaunas

2 1 st Baltic-Nordic Summer School on Neuroinformatics Computations in the Brain and Translational Neuroscience PROGRAM AND ABSTRACT BOOK INSTITUTE OF NEUROSCIENCE LITHUANIAN UNIVERSITY OF HEALTH SCIENCES Summer School webpage: May 29-31, 2013 Vytautas Magnus University Kaunas

3 WELCOME On behalf of the Organising Committee, it is a great pleasure and honour to welcome you in Kaunas, at the 1 st Baltic-Nordic Summer School in Neuroinformatics (BNNI): Computations in the Brain and Translational Neuroscience. The Summer School is held under the European Commission initiative European Month of the Brain May This event is organized jointly by INCF (International Neuroinformatics Coordinating Facility) National Node of Finland and Tampere University of Technology (Finland), Vytautas Magnus University and n University of Health Sciences (Kaunas, ), and the n Neuroscience Association. The INCF National Node of Finland has set a goal to organize a series of hands-on summer schools during The first plans for the BNNI2013 Summer School were laid down during the INCF Short Course in Neuroinformatics in 2012 (Munich, Germany) when clear need for neuroinformatics summer schools in Nordic and Baltic countries in order to raise the awareness of this important field was identified. This year the Summer School is focused on theoretical, experimental and clinical studies of synaptic plasticity, learning and memory in the brain, both in health and disease. The course combines lectures and hands-on exercises for computational modelling and analysis of brain functions. Special focus of this Summer School is Translational Neuroscience. It emphasizes how findings of translational neuroscience while using neuroinformatics tools further could be explored for better diagnosis, treatment and prevention of neuro-related disorders. The target audience of the Summer School is advanced doctoral students and researchers from various fields of neuroscience interested on how brain computes information. We selected 25 students out of more than 40 applications specializing into neuroscience, neuroinformatics, and computational neuroscience. Young students can meet each other while seniors from physics, mathematics, and computer science may update their knowledge on recent advances in neuroinformatics and computational neuroscience. We would like to thank the authors for their contributions to this Summer School and Workshop. We are grateful to Vytautas Magnus University for hosting this event, and dedicated local young students for help in organising the event. We also thank the Academy of Finland and Interlux Ltd. () for their financial support. Marja-Leena Linne, PhD, Adjunct Professor, INCF National Node of Finland, Tampere University of Technology, Finland Aušra Saudargienė, PhD, Associate Professor, Vytautas Magnus University, Rima Naginienė, PhD, n University of Health Sciences, Arimantas Tamašauskas, Dr. Habil., Professor, Department of Neurosurgery, n University of Health Sciences, Osvaldas Rukšėnas, PhD, Professor, President of n Neuroscience Association,

4 INCF: INTERNATIONAL ORGANIZATION FOR NEUROINFORMATICS COORDINATION The International Neuroinformatics Coordinating Facility (INCF), together with its 17 member countries, coordinates collaborative informatics infrastructure for neuroscience and manages scientific programs to develop standards for data sharing, analysis, modeling and simulation in order to catalyze insights into brain function in health and disease. INCF is an international organization launched in 2005, following a proposal from the Global Science Forum of the OECD to establish international coordination and collaborative informatics infrastructure for neuroscience. INCF is hosted by Karolinska Institutet and the Royal Institute of Technology, and the Secretariat is located in Stockholm, Sweden. INCF currently has 17 member countries across North America, Europe, Australia and Asia. Each member country establishes an INCF National Node to further the development of Neuroinformatics and to interface with the INCF Secretariat. The mission of INCF is to share and integrate neuroscience data and knowledge worldwide, with the aim to catalyze insights into brain function in health and disease. To fulfill this mission, INCF establishes and operates scientific programs to develop standards for neuroscience data sharing, analysis, modeling and simulation. Currently there are 4 program areas: Digital Brain Atlasing, Ontologies for Neural Structures, Multi-scale modeling, and Standards for Data Sharing. More than 180 leading international researchers are involved in the programs. INCF is also committed to supporting training in neuroinformatics. The "INCF Dataspace" has been developed to enable collaboration between researchers through the sharing of neuroscience data, text, images, sounds, movies, models and simulations. Belgium Czech Republic Finland France Germany India Italy Japan List of member countries: Netherlands Norway Poland Republic of Korea Sweden Switzerland UK USA Victoria, Australia Contacts: Malin Sandström Community Engagement Officer malin.sandstrom@incf.org INCF Secretariat, Karolinska Institutet Nobels väg 15A, SE Stockholm, Sweden Tel: Find out more: Web: Facebook: facebook.com/incforg Twitter: twitter.com/incforg Youtube: youtube.com/incforg

5 PROGRAMME 29 May (Wednesday) 2013 Neuroinformatics and Computational Neuroscience Vytautas Magnus University Conference Hall 2nd floor, Daukanto 28, Kaunas, Registration Welcome addresses Introduction to Neuroinformatics Coffee Introduction to computational modeling of brain functions: Cells, synapses, networks and beyond Marja-Leena Linne Tampere University of Technology, Finland Bruce Graham University of Stirling, UK Modeling synaptic plasticity Aušra Saudargienė Vytautas Magnus University, Lunch Multi-scale modeling of the basal ganglia Introduction to the NEURON simulator and public databases of neural models Background information for computer exercises Coffee Practicals: Computer exercise Room 306, Daukanto 28, Kaunas Student posters and presentations Sightseeing in Kaunas and Get-together Dinner Bernelių užeiga, M. Valančiaus 9, Kaunas Jeanette Hellgren Kotaleski Royal Institute of Technology, Sweden Arnd Roth University College London, UK Bruce Graham University of Stirling, UK

6 PROGRAMME 30 May (Thursday) 2013 Computations in the brain: Learning and memory Cortical dynamics of memoryguided behavior: Experimental and modeling perspectives Coffee Computational model-based analysis of neurobehavioral data Functional connectivity of resting state fmri and application in epilepsy, ADHD and depression Lunch Practicals: Computer exercise Coffee Room 306, Daukanto 28, Kaunas Practicals: Computer exercise Room 306, Daukanto 28, Kaunas Discussion: Questions on computational modeling of the brain Michael Hasselmo Boston University, USA Gediminas Lukšys Basel University, Switzerland Roma Šiugždaitė Ghent University, Belgium Bruce Graham University of Stirling, UK Gala dinner Senieji Rūsiai, Vilniaus 34, Kaunas

7 PROGRAMME 31 May (Friday) 2013 Translational Neuroscience Translational Neuroscience - bringing fundamental research into clinical practice The role of membrane properties in neuronal function Mechanisms of synaptic plasticity regulation by micro RNA Rima Naginienė n University of Health Sciences (LUHS), Gytis Svirskis LUHS, Tatiana Tkatch LUHS, Coffee Dense coding in spinal cord Aidas Alaburda Vilnius University, Microdynamics of visual receptive fields State-modulation of EEG gamma responses: towards clinical application Lunch Multivariate analysis of biomedical signals and images: the key strategy in modern biomedical data processing Gene expression and functionbased identification of biomarkers for diagnosis of glioma malignancies Beta amyloid and Alzheimer's disease Osvaldas Rukšėnas Vilnius University, Inga Griškova Bulanova Vilnius University, Algimantas Kriščiukaitis LUHS, Arūnas Kazlauskas LUHS, Vilmantė Borutaitė LUHS,

8 PROGRAMME 31 May (Friday) 2013 Translational Neuroscience Effect of transcranial magnetic stimulation therapy in treating neuropsychiatric disorders Coffee Intraoperative visualization of brain tumors: current challenges and future trends Vladas Valiulis Republic Vilnius Psychiatric Hospital, Vilnius University, Kęstutis Skauminas LUHS, Closing remarks Aušra Saudargienė Vytautas Magnus University, Visit to the Open Air Museum of and Farewell Dinner in the authentic n Tavern, Rumšiškės

9