Contact Lenses Solutions

Transcription

1 es Solutions &s u m m a r y Compiled by Paul White, OD The New England College of Optometry, Boston, Massachusetts SPONSORED BY A supplement to the July 2017 Issue of SPECTRUM

2 NEW Eve nt Plann er y Soccer Pla er h Ac ie r. e v Because I know Eric leaves no detail unchecked, I prescribe NEW ACUVUE OASYS 1-Day for ASTIGMATISM. *Helps protect against transmission of harmful UV radiation to the cornea and into the eye. WARNING: UV-absorbing contact lenses are NOT substitutes for protective UV-absorbing eyewear such as UV-absorbing goggles or sunglasses because they do not completely cover the eye and surrounding area. You should continue to use UV-absorbing eyewear as directed. NOTE: Long-term exposure to UV radiation is one of the risk factors associated with cataracts. Exposure is based on a number of factors such as environmental conditions (altitude, geography, cloud cover) and personal factors (extent and nature of outdoor activities). UV-blocking contact lenses help provide protection against harmful UV radiation. However, clinical studies have not been done to demonstrate that wearing UVblocking contact lenses reduces the risk of developing cataracts or other eye disorders. Consult your eye care practitioner for more information.

3 Two innovations combined for stable vision and exceptional comfort. + HydraLuxe Technology BLINK STABILIZED Design Tear-like molecules and highly breathable hydrated silicone integrate with the patient s own tear film. This design works naturally with the eyelids, helping to keep the lens in the correct position. For your practice... For your patients... ACHIEVE 99 % FIRST-FIT SUCCESS1 20/20 VISUAL ACUITY OR BETTER 1 for great practice efficiency To learn more about this and other EYE-INSPIRED PATIENT-FOCUSED innovations, visit acuvueprofessional.com From the contact lens family unbeaten on comfort* * In 15 clinical trials posted on a website maintained by the NIH. The 15 clinical studies evaluated subjective comfort as a primary or secondary endpoint for ACUVUE OASYS Brand with HYDRACLEAR PLUS Technology. Review conducted as of December 31, In a clinical trial, 97% of patients achieved a monocular VA 20/20 or better at the fitting visit with 100% achieving 20/25 or better. 1. Straker B, Hamada W, Sulley A, Olivares G. Fitting performance and efficiency with a low silicone daily disposable toric contact lens. Poster presented at: GSLS Conference ACUVUE Brand es are indicated for vision correction. As with any contact lens, eye problems, including corneal ulcers, can develop. Some wearers may experience mild irritation, itching or discomfort. Lenses should not be prescribed if patients have any eye infection, or experience eye discomfort, excessive tearing, vision changes, redness or other eye problems. Consult the package insert for complete information. Complete information is also available by visiting acuvueprofessional.com, or by calling Johnson & Johnson Care, Inc. at ACUVUE, ACUVUE OASYS, EYE-INSPIRED, HYDRACLEAR, BLINK STABILIZED, and HydraLuxe are trademarks of Johnson & Johnson Care, Inc. Johnson & Johnson Care, Inc B March 2017

4 Dear Colleague, Johnson & Johnson is delighted to once again sponsor the es and Solutions Summary (CLASS) supplement. As a proud sponsor of this supplement for more than a decade, we firmly believe in its value to the professional community. This year s CLASS appears as a supplement to the July issue of Spectrum, and can also be viewed at We thank Dr. Paul White and his colleagues at Spectrum for their hard work to compile the comprehensive data included within this year s summary. We also express our gratitude to our colleagues around the world for their ongoing support of the ACUVUE Brand Family of Products. Over the last 30 years as global leaders in the contact lens marketplace, we have focused on bringing healthy vision to everyone, everywhere, every day. We are steadfast in our commitment to developing new and innovative products that fulfill the unique needs of patients, beginning in 2014 with a new and exciting launch cadence. Examples include: 1-DAY ACUVUE MOIST Brand, the only multifocal contact lens that has been created with uniquely optimized optical designs to address the natural variations in pupil size according to age and refractive power ACUVUE OASYS Brand es 1-Day with HydraLuxe Technology, a tear-infused design with an enhanced network of tear-like molecules that integrates with your patients tear film each day to help support a stable tear film and reduce symptoms of tired eyes and contact lens-related dryness ACUVUE VITA Brand es, a 30-day daily wear contact lens with new HydraMax Technology that maximizes and maintains lens hydration all month long. While we believe that a shorter contact lens wearing cycle is better, we understand the challenges facing current monthly wearers and are happy to offer a solution that provides superior comfort all month long over other leading monthly brands. This year we are pleased to introduce ACUVUE OASYS Brand es 1-Day with HydraLuxe Technology for ASTIGMATISM, a unique combination of EYE-INSPIRED Design and HydraLuxe Technology, coupled with BLINK STABILIZED Design for exceptional comfort and consistent, clear, stable vision; with a reported 97% first fit success rate of patients achieving a monocular VA of 20/20 or better and the widest range of coverage for astigmatic patients in a single use lens. At Johnson & Johnson, we are committed to promoting healthy vision and safe use of contact lenses, preserving the critically important doctor-patient relationship, and developing innovative products to address a wide range of patients vision needs. We continue to focus on the eye care professionals who treat these patients, and remain active across the country in advocating and supporting the doctor-patient relationship and patient safeguards. In addition, we are excited to move further into eye health with the integration of medical devices for surgical technologies and consumer eye health products. Johnson & Johnson s goal is to address unmet needs along the entire eye care continuum. Our commitment to innovation is unwavering. But at the center of all the R&D efforts be they technological, educational, or commercial in nature is our commitment to advancing the eye care professions. We thank you for your partnership and look forward to our continued work together. We look forward to any comments you would like to share with us about our products, programs and/or policies. We can be reached at: PA@its.jnj.com. With warmest regards, Millicent Knight OD, FAAO, FAARM Vice President of Professional Affairs, Johnson & Johnson, North America ACUVUE Brand es are indicated for vision correction. As with any contact lens, eye problems, including corneal ulcers, can develop. Some wearers may experience mild irritation, itching or discomfort. Lenses should not be prescribed if patients have any eye infection, or experience eye discomfort, excessive tearing, vision changes, redness or other eye problems. Consult the package insert for complete information. Complete information is also available by calling or by visiting acuvueprofessional.com. ACUVUE, ACUVUE OASYS, HydraLuxe, 1-DAY ACUVUE MOIST, ACUVUE VITA, and HydraMax are trademarks of Johnson & Johnson Care, Inc. Johnson & Johnson Care, Inc FROM THE PUBLISHERS OF CONTACT LENS SPECTRUM

5 TO THE CONTACT LENS PRACTITIONER es & Solutions Summary s goal is to provide you with a concise, easy-to-use, chairside informational source to aid in patient care decision-making. It follows the K.I.S.S. philosophy - keep it simple and streamlined. We have incorporated list prices for soft contact lenses, however these prices are approximate, and are provided as a guideline. For exact pricing, costs for atypical powers or other parameters, warranty or exchange policies, or for more information about products, contact the manufacturers and distributors listed on Page 35. To provide you with a method to compare lens designs, we ve taken the liberty of standardizing manufacturers descriptions of their lens parameters. Unless otherwise indicated, center thickness specified is for average minus power. We ve arranged lenses by brand name rather than by company because that s how we refer to them in practice. In addition, ongoing corporate acquisitions make brand identification a more consistent system as all names are registered or trademarked. In addition to registered or trademarked names, each material has a generic name. Because an understanding of generic materials is important as it relates to disinfection systems and Dk values, please take a moment to read the information under Hydrogel and Hydrogel Lens General Considerations on Page 7. Due to the growing popularity of silicone contact lens prescribing and in response to reader requests, we have made the words bold in all silicone lens listings to make those listings easier to locate. We trust the es & Solutions Summary continues to fulfill your needs. It is made possible through an educational grant from Johnson & Johnson. Paul White, OD P.S. A PDF of es & Solutions Summary is available for download at Published by: Spectrum, Penta LLC, Norristown Road, Suite 150, Ambler, PA (267) clspectrum@pentavisionmedia.com Contents Diopters to Radius of Curvature Conversion Table 6 Vertex Distance Table 6 SOFT CONTACT LENSES General Considerations 7 Disposable / Planned Replacement Spherical Clear and Visibility Tint 8 Tinted Enhancer and Opaque 11 Toric 12 Multifocal 15 Spherical Clear and Visibility Tint Daily Wear 17 Extended Wear 20 Therapeutic 21 Aphakic 21 Special Design 21 Tinted Enhancer and Opaque Daily Wear 24 Customized Tinting 25 Toric Daily Wear 25 Extended Wear 26 Multifocal Daily Wear 26 Extended Wear 28 Multifocal Toric 28 Hybrid Soft/GP 29 GAS PERMEABLE (GP) LENSES General Discussion 30 Lens Materials 30 SOLUTIONS Rigid Lens Solutions 31 Soft Lens Solutions Non-Thimerosal Preserved Saline 32 Unpreserved Saline 32 Daily Cleaners 32 Weekly Cleaners 33 Daily Protein Removers 33 Disinfecting Solutions and Combinations 33 Hydrogen Peroxide Disinfection 33 Subsonic / UVC Disinfection 34 Lubricants / Rewetting Drops 34 Company Directory 35 For additional copies of CLASS, contact: Geri Berzinski (267) gerianne.berzinski@pentavisionmedia.com clspectrum.com/class CONTACT LENSES & SOLUTIONS SUMMARY 5

6 Diopters to Radius of Curvature Conversion Table D.R. D.R. D.R. D.R. D.R. D.R. D.R Vertex Distance Table Average 12 mm DISTANCE MINUS MINUS PLUS PLUS Left-Right Left-Right Right-Left Right-Left = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = FROM THE PUBLISHERS OF CONTACT LENS SPECTRUM

7 Soft es Hydrogel and Hydrogel Lens General Considerations The FDA gives each contact lens material a generic name. In general, all and silicone lens generic names end in the suffix filcon and all non lenses end in focon. Hydrogel lenses are categorized into five groupings for purposes of evaluating effects of accessory products upon the lens material. Lenses with less than 50 percent water content are considered to be low water and the others are high water. Less reactive surfaces are termed nonionic and more reactive materials are labeled ionic. lenses are Group 5, which is in the process of being updated and subdivided further. This is described in the article Proposed Hydrogel Lens Grouping Systems for Lens Care Product Compatibility Testing by Joseph Hutter, PhD, Angela Green, PhD, and Malvina Eydelman, MD, in Eye and, 2012 Nov;38(6): The FDA proposal has been sent out for comments, and it will then be finalized. Disinfection of and silicone lenses can usually be done safely and effectively by approved chemical or hydrogen peroxide systems. However, some Group 4 ionic polymers may react negatively with potassium sorbate- or sorbic acidpreserved solutions. In the term Dk, D stands for diffusion and k for solubility. The oxygen permeability of lenses is almost entirely the result of solubility and for GP materials almost GROUP 1 Low Water (<50% H 2 O) Nonionic Hydrogel Polymers tefilcon (38%) (Dk = 8.9) LL Bifocal tetrafilcon A (43%) (Dk = 10.3) Preference (Dk = 26.6) Preference Toric Preference Toric XR helfilcon A&B (45%) (Dk = 12) Continental Toric Flexlens Aphakic Flexlens Optima Toric Flexlens Toric polymacon (38%) (Dk = 9) Alden Classic 38 LifeStyle Toric Sphere and Toric Bifocal Clearcolor lenses LL-38 Esstech PS Multifocal Metrosoft II Esstech PSD Metrosoft Toric Esstech SV Natural Touch HD Occasions HD-T Optima 38 HDX Simulvue 38 HDX-T Sof-form II Horizon 38 SofLens 38 Ideal Soft SofLens LifeStyle MV2 Multi-Focal LifeStyle Xtra Unilens 38 LifeStyle 4Vue Westhin Toric hioxifilcon B (49%) (Dk = 15) Alden HP Sphere Intelliwave Alden HP Toric Multifocal Toric Aquaease Quattro Essential Soft Satureyes Toric Multifocal Satureyes Toric Flexlens and Multifocal Intelliwave SpecialEyes 49 Intelliwave Toric and Sphere Toric Intelliwave Multifocal Note: All X-Cel lenses are available in helfilcon A, hioxifilcon A, hioxifilcon B, and methafilcon A. GROUP 2 High Water (>50% H 2 O) Nonionic Hydrogel Polymers alfafilcon A (66%) (Dk = 32) SofLens Toric for Astigmatism omafilcon A (60%) (Dk = 33) Biomedics XC (Dk = 44) Proclear 1-Day omafilcon B (62%) (Dk = 34) Proclear Multifocal and Multifocal Toric) Proclear Sphere Proclear Toric clspectrum.com/class hioxifilcon A (59%) (Dk = 28) Alden HP 59 Sphere Alden NovaKone Extreme H 2 O 59% Thin Extreme H 2 O 59% Extra Extreme H 2 O Monthly Eyedia Precise Monthly, Fresh Daily Disposable, Precise Monthly for Astigmatism Miru 1Day Menicon Flat Pack SpecialEyes 59 Toric and Sphere hioxifilcon D (54%) (Dk = 21) Alden HP 54 Sphere and Toric Astera Multifocal Astera Multifocal Toric C-Vue Advanced Custom Toric, SV, Multifocal, Toric Multifocal Extreme H 2 O 54% Extreme H 2 O 54% Toric Extreme H 2 O Monthly NovaKone, NovaKone Toric SpecialEyes 54 Toric, Sphere, Multifocal, Bifocal nelfilcon A (69%) (Dk = 26) Dailies AquaComfort Plus Focus Dailies Focus Dailies Toric Focus Dailies FreshLook One-Day Novakone, Novakone Toric Synergy Triton nesofilcon A (78%) (Dk = 42) Biotrue Oneday Biotrue Oneday for Astigmatism Biotrue Oneday for Presbyopia hilafilcon B (59%) (Dk = 22) SofLens Daily Disposable SofLens Daily Disposable for Astigmatism acofilcon A (58%) Dk = (25.5) Flexlens Tricurve Keratoconus GROUP 3 Low Water (<50% H 2 O) Ionic Hydrogel Polymers deltafilcon A (43%) (Dk = 10) Metrosoft GROUP 4 High Water (>50% H 2 O) Ionic Hydrogel Polymers etafilcon A (58%) (Dk = 28) 1-Day Acuvue Define A+ Wave 1-Day Acuvue Moist Acuvue 2 1-Day Acuvue Moist for Astigmatism 1-Day Acuvue Moist Brand Multifocal Eyedia Soft NaturalVue Multifocal 1 Day entirely the result of diffusion. In silicone materials, oxygen permeability is a combination of solubility and diffusion, with the larger amount from diffusion. That is, the component in the formulation provides solubility and the silicone component provides diffusion. Each generic material below is accompanied by a representative Dk number. A clinically useful approximation is to consider Dk values for lenses in three groups: H 2 O Dk 38±% 9± 55±% 18± 75±% 36± It is also important to remember that Dk/t (central transmissibility) and Dk/t (average overall transmissibility) are dependent upon contact lens thickness configuration and are more important than Dk with lenses. With silicone contact lenses, Dk/t and Dk/t are more similar than with lenses. This table should assist you in identifying specific lenses in each category as related to disinfection and Dk; and it will also help you determine an appropriate mix of lens types for your practice. focofilcon A (55%) (Dk = 16) Fre-Flex ocufilcon A (46%) (Dk = 15) UCL Tresoft UCL PR-46 ocufilcon B (52%) (Dk = 16) ClearSight 1 Day Ocu-Flex 53 Continental ocufilcon C (55%) (Dk = 16) UCL 55 UCL-Pediatric ocufilcon D (55%) (Dk = 19.7) Biomedics 55 Premier (Dk = 28.1) Biomedics Toric ClearSight 1 Day Toric ocufilcon E (65%) (Dk = 22) Ocuflex 65 phemfilcon A (55%) (Dk = 16) Freshlook Freshlook Toric Freshlook Colorblends Colors Dimensions methafilcon A (55%) (Dk = 18) Alden Classic 55 Sphere Alden Classic 55 Toric Biocurve Advanced Biocurve 1-Day Comfort C-Vue 1 Day ASV and ASV C-Vue 55 Multifocal and Custom Toric Definition AC, Definition AC Comfort Elite AC Elite Daily Elite AC Toric Eyedia Soft 55 Flexlens Frequency 55 Sphere & Multifocal HD2 HDX2 Horizon 55 Bi-Con isight Sphere, Toric, Multifocal Kontur LL 55 New Horizons Sof-form 55 EW and Aphakic Softcon EW-2 Vertex Sphere Vertex Toric methafilcon B (55%) (Dk = 18) Frequency 55 Toric Hydrasoft Sphere Hydrasoft Aphakic Hydrasoft Toric vilfilcon A (55%) (Dk=16) Focus Monthly Softcolors Soft 55 Soft 55 EW GROUP 5 Hydrogel Polymers lotrafilcon A (24%) (Dk = 140) Air Optix Night & Day Aqua lotrafilcon B (33%) (Dk = 110) Air Optix Aqua Air Optix Aqua Multifocal Air Optix for Astigmatism Air Optix Plus HydraGlyde narafilcon A (46%) (Dk = 100) 1-Day Acuvue TruEye senofilcon A (38%) (Dk = 103) Acuvue Oasys Acuvue Oasys 1-Day Acuvue Oasys 1-Day for Astigmatism Acuvue Oasys for Astigmatism Acuvue Oasys for Presbyopia senofilcon C (41%) (Dk = 103) Acuvue Vita comfilcon A (48%) (Dk = 128) Biofinity (Dk = 160) Biofinity Toric Biofinity Multifocal Biofinity XR enfilcon A (46%) (Dk = 125) Avaira Avaira Toric (Dk = 90) balafilcon A (36%) (Dk = 112) C-Vue Hydravue Multifocal Pure Pure Multi-Focal and Toric Pure2 Pure2 Toric for Astigmatism Pure2 Multi-Focal for Presbyopia efrofilcon A (74%) (Dk = 60) C-Vue Hydravue C-Vue Hydravue Custom Toric C-Vue Hydravue Multifocal C-Vue Hydravue Toric Multifocal Intelliwave Intelliwave Toric Intelliwave Multifocal Intelliwave Multifocal Toric KeraSoft IC Metrofocal Definitive Metrofocal Toric Definitive Metrosoft Definitive Metrosoft Toric Definitive Revitaleyes Post-Refractive Definitive Rose K2 Soft delefilcon A (33% core, 80% surface) (Dk = 140) Dailies Total1, Dailies Total1 Multifocal fanfilcon A (55%) (Dk = 90) Avaira Vitality Avaira Vitality Toric somofilcon A (56%) (Dk = 60) Clariti 1 Day Clariti 1 Day Multifocal Clariti 1 Day Toric samfilcon A (46%) Dk = 163 Bausch + Lomb Ultra, Ultra for Presbyopia olifilcon A (47%) (Dk = 175) Biocurve Spherical CONTACT LENSES & SOLUTIONS SUMMARY 7

8 Spherical Clear and Visibility Tint Disposable and/or Planned Replacement Hydrogels Trade Name Manufacturer Material %H 2 O Thickness Diameters Base Curves Powers Price 1-DAY ACUVUE MOIST (1) 1-DAY ACUVUE TRUEYE (1) ACUVUE 2 (1, 2, 3) Johnson ACUVUE OASYS ACUVUE OASYS 1-DAY (1) ACUVUE VITA (2) AIR OPTIX AQUA (1, 2, 3) Johnson (2, 3) AIR OPTIX NIGHT & (2, 4) DAY AQUA AIR OPTIX PLUS HYDRAGLYDE ALDEN CLASSIC 38 SPHERE (2) ALDEN CLASSIC 55 SPHERE (2) ALDEN HP 49 SPHERE (2) ALDEN HP 54 SPHERE (2) ALDEN HP 59 SPHERE (2) Johnson & Johnson Johnson & Johnson & Johnson & Johnson Johnson & Johnson Johnson & Johnson Alden Optical Alden Optical Alden Optical Alden Optical Alden Optical /MA UV blocker (Class 2) Lacreon Technology UV blocker (Class 1) Hydraclear 1 Technology /MA UV blocker (Class 2) UV blocker (Class 1) Hydraclear Plus Technology UV blocker (Class 1) HydraLuxe Technology UV blocker (Class 1) HydraMax Technology Clear or visibility tint Clear or visibility tint GMA/ Clear or visibility tint GMA/ Clear or visibility tint GMA/ Clear or visibility tint , , , , 8.8 Plano bandage lens: 8.4, , , to +6 beyond 6 12 to +6 beyond 6 12 to +8 beyond ±6 12 to +8 beyond ±6 12 to +8 beyond ±6 12 to +8 beyond ±6 10 to to pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ , to +6 6-pack/ to to to to to to to to +6 (0.25D steps) +8 to and 8.50 to 12 () No plano 30 to to +30 ±10.25 to ±30 30 to pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ to AVAIRA (2) after 6 +8 to pack/ after +6 AVAIRA VITALITY (2) to +8 6-pack/19.75 A+ WAVE Optical Connection Single and 12-pack/ to +4 UV blocker Call for pricing BAUSCH + LOMB ULTRA (2) Bausch + Lomb MoistureSeal Technology to +6 ( above 6) 6-pack/30.50 BIOCURVE 1-DAY 30-pack/12.99 Optical Connection to +6 COMFORT (1) 90-pack/37.99 BIOCURVE ADVANCED Optical Connection (1, 2) ASPHERIC , to +8 6-pack/13.99 BIOCURVE SPHERICAL SILICONE Optical Connection to pack/40.00 BIOFINITY (2, 3) to +8 6-pack/29.50 BIOFINITY XR (2, 3) to to 20 6-pack/32.00 BIOMEDICS 55 (1, 3) PREMIER BIOMEDICS XC (1) UV blocker /PC , 8.9 ( ), 8.8 (+) to +6 6-pack/ to +6 after 6 6-pack/25.50 (1) Disposable (2) Planned Replacement (3) Extended Wear (EW) Approval (4) Continuous Wear (CW) Approval 8 FROM THE PUBLISHERS OF CONTACT LENS SPECTRUM

9 Spherical Clear and Visibility Tint Disposable and/or Planned Replacement Hydrogels - continued Trade Name Manufacturer Material %H 2 O Thickness Diameters Base Curves Powers Price BIOTRUE ONEDAY (1) CLARITI 1 DAY (1) CLEARSIGHT 1 DAY (1) C-VUE ADVANCED HYDRAVUE SINGLE VISION C-VUE ADVANCED SINGLE VISION Bausch + Lomb Hypergel UV blocker UV blocker UV blocker Unilens 74 Unilens GMA/ to 16.0 (14.5, 15.0 std.) 12.0 to 16.0 (14.5, 15.0 std.) 8.0 to 9.5 (8.2, 8.5, 8.8, 9.1 std.) 8.0 to 9.5 (8.2, 8.5, 8.8, 9.1 std.) 9 to +6 ( beyond 6.50) 10 to +8 >±6 10 to +6 > 6 and to to pack/ pack/ pack/ pack/ pack/ pack/ Trial/ pack/ Trial/20.00 C-VUE 55 ASPHERIC (2) Unilens to +8 6-pack/15.00 C-VUE 1 DAY ASV (1) Unilens to pack/ pack/ to 0.50 DAILIES to +8 PVA 30-pack/16.40 AQUACOMFORT ( 15 to and Visitint 90-pack/40.80 PLUS (1) +6 to +8 in 0.50D steps) DAILIES TOTAL1 (1) core material; High-water, non-silicone surface material 33 Surface water content to to +6 ( over 6) 30-pack/ pack/65.00 DEFINITION AC (2) Optical Connection , to +8 6-pack/13.99 DEFINITION AC 30-pack/12.99 EVERYDAY Optical Connection to pack/37.99 COMFORT (1) ELITE (2) Ocu-Ease/ 55 Varies , to +8 6-pack/11.50 ELITE AC DISPOSABLES (1) Ocu-Ease/ 55 Varies , to +8 6-pack/12.50 ELITE DAILY (1) Ocu-Ease/ 55 Varies to pack/ pack/ to Median to +6 EXTREME H 2 O 6-pack/17.95 GMA to % (1, 2) 12-pack/ Median to +6 ( after 6) 8 to 0.50 EXTREME H 2 O GMA Median to +6 59% THIN (1, 2) ( after 6) 6-pack/ to 0.50 EXTREME H 2 O Median 86 GMA to +6 59% XTRA (1, 2) Steep to 8 6-pack/ Median to to +6 EXTREME H 2 O X-Cel (1, 2) DAILY EXTREME H 2 O X-Cel (1, 2) MONTHLY EXTREME H 2 O X-Cel (1, 2) WEEKLY EYEDIA FRESH DAILY DISPOSABLE Clearlab 14.2 Median to to +6 GMA Steep to to Median to +6 above 6 Median to to GMA Flat to to Steep 81 ( after 6.00D) 13.6 Median to to Median to to +6 GMA Steep to to Median to +6 above 6 GMA/ (For +4 to +6) 10 to +6 ( > 6 and +4) 30-pack/ pack/ pack/ pack/ pack/ pack/37.90 (1) Disposable (2) Planned Replacement (3) Extended Wear (EW) Approval (4) Continuous Wear (CW) Approval clspectrum.com/class CONTACT LENSES & SOLUTIONS SUMMARY 9

10 Spherical Clear and Visibility Tint Disposable and/or Planned Replacement Hydrogels - continued Trade Name Manufacturer Material %H 2 O Thickness Diameters Base Curves Powers Price EYEDIA PRECISE MONTHLY EYEDIA SOFT 55 EYEDIA SOFT 58 FLEXLENS SPHERE (2) FLEXLENS PRISM SPHERE (2) FOCUS DAILIES (1) FREQUENCY 55 ASPHERIC (2) FRESHLOOK (1, 2, 3) HANDLING TINT HD (2) HD2 (2) Clearlab Clearlab Clearlab PolyVue PolyVue GMA/ UV blocker /MA UV blocker /GMA/ Clear or handling tint /GMA/ Clear or handling tint PVA AquaRelease Visitint /MMA 10 FROM THE PUBLISHERS OF CONTACT LENS SPECTRUM , 49, 55, 59, 74 45, 49, 55, 59, Varies Varies 14.0 ( ) 14.5 (+) 8.2, 8.6 ( ) 8.6 (+) 13.5 to to 9.2 (0.1) 6.0 to 11.0 Custom available 13.5 to to to 11.0 Custom available of 1.50/ to +6 ( > 6 and +4) 12 to +6 ( > 6 and +4) 10 to +6 ( > 6 and +4) 40 to to to to to to +8 8 to steps > 6 and to +6 6-pack/ pack/ pack/13.50 First lens/ pack/ pack/ pack/72.00 First lens/ pack/ pack/ pack/ pack/ pack/ pack/ pack/21.90 Single lens/24.00 Multipack (3+1)/ to +8 6-pack/32.00 HD DAILIES PolyVue GMA HORIZON SPHERE (2) HORIZON PRISM SPHERE (2) /GMA/ Clear or handling tint /GMA/ Clear or handling tint 38, 49, 55, 59, 74 38, 49, 55, 59, 74 Varies Varies HYDRASOFT SPHERE (2) IDEAL SOFT INTELLIWAVE ASPHERIC (2) isight SPHERE (3) AND GOLD SPHERE (FORMERLY BIOCURVE) METROLITE PLANNED REPLACEMENT (2) METROLITE M SERIES PLANNED REPLACEMENT (2) METROSOFT II PLANNED REPLACEMENT (2) METROSOFT II M SERIES PLANNED REPLACEMENT (2) METROSOFT DEFINITIVE Art Optical GP Specialists of Austin 74 with handling tint 49 GMA/ Light blue Light blue 13.5 to to to to to to / , , 8.6, 8.9, Varies , 8.6, , to steps > 6 and to to +40 First lens/ pack/ pack/ pack/72.00 First lens/ pack/ pack/ pack/ to pack/ to +20 after 8.00 MTO MTO MTO 20 to to to to , 8.6, 8.9 Plano to ±10 First lens/ pack/ pack/ pack/72.00 Diagnostic lens/ pack/60.00 Diagnostic lens/ pack/40.00 First lens/30.99 Spare lens/ pack/ pack/ pack/68.00 >±10 4-pack/ to Plano 4-pack/ , 8.6, 8.9 Plano to ±10 4-pack/65.00 >±10 4-pack/ to Plano 4-pack/65.00 Clear or visitint (1) Disposable (2) Planned Replacement (3) Extended Wear (EW) Approval (4) Continuous Wear (CW) Approval 74 Varies , 8.6, 8.9 Over ±10 Single/ pack/ Single/ pack/140.00

11 Spherical Clear and Visibility Tint Disposable and/or Planned Replacement Hydrogels - continued Trade Name Manufacturer Material %H 2 O Thickness Diameters Base Curves Powers Price MIRU 1DAY MENICON FLAT PACK (1) MYDAY (1) NATURASOFT PEDIATRIC (2) NATURASOFT SPHERE (2) Menicon Advanced Advanced /GMA Smart Technology UV blocker Clear/visitint Clear/visitint OCU-FLEX 55 (2) Ocu-Ease/ , to 0.50, to to +8 ( beyond +5 and 6 74 Varies 10.0 to to to Varies 10.0 to to to , 14.5, to 8.8 (0.1) 20 to +10 PREFERENCE (2) /NVP/MMA 10 to , 8.7 > 6.5 PREFERENCE /NVP/MMA 10 to , 8.6 STANDARD (2) > 6.5 PROCLEAR (2) 20 to /PC > ± to Plano 8.2 > 6 PROCLEAR 1-DAY (1) /PC to +8 > to 0.25 (2, 4) PUREVISION Bausch + Lomb to over 6.50 (2, 4) PUREVISION2 Bausch SATUREYES (2) (2, 3) SOFLENS 38 Bausch SOFLENS DAILY DISPOSABLE (1) SPECIALEYES (2) 54 SPHERE SPECIALEYES (2) 59 SPHERE SYNERGY QUARTERLY REPLACEMENT SPHERE (2) UNITED CONTACT LENS PLANNED REPLACEMENT (2) + Lomb + Lomb Bausch + Lomb SpecialEyes SpecialEyes Gelflex Laboratories United Contact Lens to +6 over 6.50 Call for pricing 90-pack/55.00 First lens/ pack/ pack/ First lens/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/41.50 GMA/ , 8.4, pack/ , 8.7, to +4 6-pack/ to to to to to to to above 7 25 to to , to 9.2 (0.2) 20 to +20 GMA/ 49 /NVP , 14.8, , 14.5, , 14.5, to to , 8.3, 8.6, 8.9, , 8.6, 8.9, to to , 8.5, 8.8 Over ±9 Disposable and/or Planned Replacement Tinted Enhancer and Opaque Hydrogels Trade Name Manufacturer Material %H 2 O Thickness Diameters Base Curves Powers Price 1-DAY ACUVUE DEFINE (1) AIR OPTIX COLORS ALDEN CLASSIC (2) AND ALDEN HP 49 (2) EXPRESSIONS (2) Johnson & Johnson Alden Optical /MA Peripheral limbal ring tint to clear at center UV blocker (Class 2) Lacreon technology Natural Sparkle, Natural Shimmer, Natural Shine, Accent, Vivid Subtle colors: Pure hazel, blue, green, gray, brown; Vibrant colors: Honey, brilliant blue, gemstone green, sterling gray Aqua, azure, blue, brown, gray, green, jade, walnut, yellow Gray, green, hazel, blue, aqua, blue topaz, brown, jade , to to 0.75 (0.25 steps) to 0.50 & 6.50 to 9 (including plano, ) 6 to D steps 8 to 6 ±10.25 to ±30 90-pack/35.50 Single/ pack vials/ pack vials/ Single/ pack vials/ pack vials/ Call for pricing Single/ pack vials/44.00 Single/ pack vials/68.00 Custom/44.00 Super Custom/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ to +4 6-pack/46.00 (1) Disposable (2) Planned Replacement (3) Extended Wear (EW) Approval (4) Continuous Wear (CW) Approval clspectrum.com/class CONTACT LENSES & SOLUTIONS SUMMARY 11

12 Disposable and/or Planned Replacement Tinted Enhancer and Opaque Hydrogels- continued Trade Name Manufacturer Material %H 2 O Thickness Diameters Base Curves Powers Price EYEDIA CLEARCOLOR CIRCLE EYEDIA CLEARCOLOR ELEMENT EYEDIA CLEARCOLOR ELEMENT EYEDIA CLEARCOLOR PHANTOM EYEDIA CLEARCOLOR VIBRANT FRESHLOOK (1, 2) COLORBLENDS FRESHLOOK (1, 2) COLORS FRESHLOOK ONE-DAY (1) FRESHLOOK (1, 2) DIMENSIONS HD PRO COLORS METROTINT PLANNED REPLACEMENT (2) METROTINT M SERIES PLANNED REPLACEMENT (2) Clearlab Clearlab Clearlab Clearlab Clearlab PolyVue Distribution Enhancers: New equinox, gray, brown, blue Enhancers: Violet rose, green envy, sky blue, brown chestnut, blue rain, platinum gray, misty gray, hazel autumn, tosca Enhancers: Violet rose, green envy, sky blue, brown chestnut, blue rain, platinum gray, misty gray, hazel autumn, tosca Enhancers: call company Enhancers: Leaf green, ice blue, amber, Pacific blue, slate gray, lavender, emerald, azure, mocha /MMA Amethyst, blue, brown, gray, green, honey, pure hazel, true sapphire, turquoise, brilliant blue, gemstone green, sterling grey /MMA Blue, green, hazel, violet PVA Blue, green, pure hazel, gray ColorBlends /MMA Caribbean aqua, Pacific blue, Sea green Gray, true sapphire, green, amethyst, hazel, turquoise, honey, brown Aqua, blue, green Aqua, blue, green Toric Disposable and/or Planned Replacement Hydrogels Median to +4 ( > 6) 8 to +4 ( > 6) 15 to plano (0.25D steps) Cylinder up to 4.50 Axes around the clock (5º steps) 6 to plano (select patterns) 8 to +4 ( > 6) 8 to +6 > 6 and +2 8 to +6 > 6 and +2 6-pack/ pack/ pack/75.00 MTO 6-pack/ pack/ pack/ pack/ to pack/ to +6 > 6 and +2 6-pack/ to +4 2-pack/ , 8.6, 8.9 Plano to ±10 4-pack/ >±10 4-pack/ to Plano 4-pack/ Trade Name Manufacturer Material %H 2 O Diameters Base Curves Spheres Cylinders Axis Ballast Price 1-DAY ACUVUE MOIST FOR ASTIGMATISM ACUVUE OASYS BRAND 1-DAY FOR ASTIGMATISM Johnson & Johnson Johnson & Johnson UV blocker (Class 2) Lacreon Technology Scribe marks at 6 and 12 o clock UV blocker (Class 1) HydraLuxe Technology Scribe marks at 6 and 12 o clock to Plano 9 to 6.50 () 6 to Plano 9 to 6.50 () to +4 6 to Plano 9 to 6.50 () to º, 20º, 60º, 70º, 80º, 90º, 100º, 110º, 120º, 160º, 170º, 180º 20º, 90º, 160º, 180º 180º ±20º 90º ±20 20º steps 10º, 20º, 70º, 80º, 90º, 100º, 110º, 160º, 170º, 180º 10º, 20º, 70º, 80º, 90º, 100º, 110º, 160º, 170º, 180º 10º, 20º, 70º, 80º, 90º, 100º, 110º, 160º, 170º, 180º Blink Stabilized Design Blink Stabilized Design 30-pack/ pack/ pack/ (1) Disposable (2) Planned Replacement (3) Extended Wear (EW) Approval (4) Continuous Wear (CW) Approval 12 FROM THE PUBLISHERS OF CONTACT LENS SPECTRUM

13 Toric Disposable and/or Planned Replacement Hydrogels - continued ACUVUE OASYS FOR ASTIGMATISM (1, 2, 3) AIR OPTIX FOR ASTIGMATISM (2, 3) Trade Name Manufacturer Material %H 2 O Diameters Base Curves Spheres Cylinders Axis Ballast Price Johnson & Johnson UV blocker (Class 1) Hydraclear Plus Technology ALDEN CLASSIC 38 (2) Alden Optical 38 ALDEN CLASSIC Alden Optical (2) to 15.0 ALDEN HP 49 (2) Alden Optical GMA/ ALDEN HP 54 (2) Alden Optical ALDEN HP 59 (2) Alden Optical GMA/ AVAIRA AVAIRA VITALITY (2) BAUSCH + LOMB ULTRA FOR ASTIGMATISM BIOFINITY (2, 3) BIOFINITY (2, 3) XR BIOMEDICS (2, 3) BIOTRUE ONEDAY FOR ASTIGMATISM Bausch + Lomb Bausch + Lomb CLARITI 1 DAY (1) CLEARSIGHT 1 DAY (1) Moisture Seal Technology UV blocker Hydragel UV Blocker 6.5 to to , 8.6, , 8.6, , 8.6, to +6 9 to 6.50 () 6 to to 6.50 () 1.75, 2.25, , to to to to to to 10 Any 0.25 to 10 Any ±10.25 to ± to 10 Any 0.25 to 10 Any ±10.25 to ± to 10 Any 10 to +6 after ± to to plano to ( after ±6) to to to to plano after 6.50D to D steps 9 to plano after to Plano 1.75, , , , to 5.75 () 0.75 to 2.25 () 1.75, California CO SOFT (2) to 3.25 Optics C-VUE , 8.5, 8.8 ADVANCED Unilens GMA/ to +20 Up to 4 CUSTOM (2) 10º to 180º 10º to 180º 10º to 180º 10º to 180º Blink Stabilized Design Precision Balance 8 4 Symmetric Stabilization Symmetric Stabilization Symmetric Stabilization Optimized ballast Optimized ballast Optimized ballast 5º to 180º 5º steps Optimized ballast 5º to 180º 5º steps 90º ±30º 180º ± 20º 10º, 20º, 60º, 70º, 80º, 90º, 100º, 110º, 120º, 160º, 170º, 180º 20º, 70º, 90º, 110º, 160º, 180º 10º, 20º, 90º, 160º, 170º, 180º 180º, 160º, 20º, 90º (20º and 160º not available above 7.50) 5º steps 1º steps Periballast ballast 6-pack/ pack / pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/65.00 to pack/ Trial/20.00 (1) Disposable (2) Planned Replacement (3) Extended Wear (EW) Approval (4) Continuous Wear (CW) Approval clspectrum.com/class CONTACT LENSES & SOLUTIONS SUMMARY 13

14 Toric Disposable and/or Planned Replacement Hydrogels - continued Trade Name Manufacturer Material %H 2 O Diameters Base Curves Spheres Cylinders Axis Ballast Price C-VUE ADVANCED HYDRAVUE CUSTOM (2) DAILIES AQUACOMFORT PLUS ELITE AC (2) EXTREME H 2 O 54% (1, 2) LC EXTREME H 2 O 54% (1, 2) MC EYEDIA PRECISE MONTHLY FOR ASTIGMATISM FLEXLENS (2) FLEXLENS ARC FOCUS DAILIES (1) Unilens Ocu-Ease/ X-Cel X-Cel Clearlab X-Cel X-Cel FREQUENCY 55 (2, 3) PVA Blue visitint to 16.0 (14.5, 15.0 std.) 8.0 to 9.5 (8.2, 8.5, 8.8, 9.1 std.) to +20 Up to 4 6 to +4 8 to 6.50 () to +4 1, 1.75 GMA Median 86 6 to +4 LC (0.65D) GMA Median 86 6 to +4 MC (1.25D) GMA/ Single indication line at 6 o clock /GMA/ Clear or handling tint PVA Aqua Release Visitint to +4 1, 1.75 Any 1º steps 90º ±20º 180º ±20º 15º steps 10º, 20º, 80º, 90º, 100º, 160º, 170º, 180º 6-pack/ Trial/ pack/ pack/ pack/ pack/ pack/ pack/ to to to 10 Any First lens/ , 49, 55, 59, 74 3-pack/ pack/72.00 Custom available 6.0 to to to 10 Any 12-pack/ First lens/ to to to to 10 Any 3-pack/ pack/ pack/ to , , to , º, 90, 110º, 160º, 180º, 20º 10º to 180º 30-pack/ pack/ pack/51.25 FREQUENCY 55 (2, 3) XR HD-T (2) HORIZON (2) PolyVue X-Cel /GMA/ Clear or handling tint , to to to , , 55, 59, 74 HYDRASOFT (2) 55 INTELLIWAVE ASPHERIC (2) isight SOFT (FORMERLY BIOCURVE) KONTUR 55 (2) METROSOFT DEFINITIVE METROSOFT (2) NATURASOFT (2) Art Optical GP Specialists Kontur Kontact Lens Advanced OPTIMA (2) Bausch + Lomb with handling tint Clear or visibility tint Clear or Clear Clear/visitint 5º to 180º 5º steps 180 ±20º 90º ±20º 6-pack/85.00 Single/24.00 Multipack (3+1)/ to 15.0 Custom available 8.0 to to to to to 10 Any Any First lens/ pack/ pack/ pack/ , to +30 ; 0.50 to 10 Any Eccentric 3-pack/ , 8.6, 8.9, to +30 lenticulation Diagnostic to 12 /65.00 MTO MTO 20 to to 12 1º to 180º 1º steps 55, to to to to 8.50 Any 14.0, 14.5, 15.0, , 8.3, 8.6, to to 5 (4) Any 1º steps ; Eccentric lenticulation , 8.7, to 8 5º steps , 8.7, to over to to to to 15 /NVP , 8.6, to , 2.25, 2.75, 3.25, 3.75, º steps 1º to 180º (1º steps) 5º steps 4-pack/ Diagnostic / pack/70.00 Single/ pack/ pack/71.99 Spare lens/ to 45.00/lens Single/ pack/ pack/ Single/55.00 First lens/ pack/ pack/ pack/ Single vial/82.00 (1) Disposable (2) Planned Replacement (3) Extended Wear (EW) Approval (4) Continuous Wear (CW) Approval 14 FROM THE PUBLISHERS OF CONTACT LENS SPECTRUM

15 Toric Disposable and/or Planned Replacement Hydrogels - continued Trade Name Manufacturer Material %H 2 O Diameters Base Curves Spheres Cylinders Axis Ballast Price PREFERENCE (2) PREFERENCE XR (2) /PVA/ MMA /PVA/ MMA , to , to +6 PROCLEAR /PC , to +6 (2) PROCLEAR /PC , 8.8 XR (2) PUREVISION (2, 4) Bausch + Lomb PUREVISION2 FOR ASTIGMATISM (2, 4) Bausch + Lomb SATUREYES (2) SOFLENS DAILY DISPOSABLE Bausch + FOR Lomb ASTIGMATISM (1) SOFLENS 66 Bausch + (2, 3) Lomb SPECIALEYES 59 (2) SpecialEyes SPECIALEYES SE 54 (2) SYNERGY QUARTERLY REPLACEMENT (2) UCL 55 UCL TRESOFT SpecialEyes Gelflex Laboratories United United GMA/ to +6 ( above 6) 9 to +6 ( above 6.00) 1.75, 2.25 (2) 5º to 180º 5º steps 2.75 to 9.75 (0.25D steps) 1.75, to 5.75 () 1.75, , º to 180º 5º steps 10º to 180º 5º to 180º 5º steps ; Eccentric lenticulation ; Eccentric lenticulation Hybrid Peri and , to to 4 5º steps GMA/ 49 /NVP to to , 14.8, , 14.5, to to , 8.3, 8.6, 8.9, , 8.6, 8.9, to plano ( above 6.50) 9 to +6 ( above 6.50) , 2.25, º, 90º, 160º, 180º 15 to to 8 Any 15 to to 8 Any +40 to 40 Up to 10 Any 1º steps Biprism 20 to +20 Any Slab-off , , 8.5, to to 8 Any VERTEX (2, 3) to , 2.25 XR 2.75, 3.25, º to 180º 5º to 180º 5º steps 4-pack/ pack/ pack/ pack/ pack/ pack/ pack/ Single/ pack/ pack/26.60 Single/ pack vials/ pack vials/ Single/ pack vials/ pack vials/ Initial lens/ pack within 90 days/33.00 Single/ pack/ Single/ pack/ pack/ pack/71.00 WESTHIN X-Cel /GMA/ Clear or handling tint 49, 55, 59, to to to to 10 Any Multifocal Disposable and/or Planned Replacement Hydrogels Double Slab-off Trade Name Manufacturer %H 2 O Diameters Base Curves Powers Adds Designs Price First lens/ pack/ pack/ pack/ DAY ACUVUE MOIST BRAND (1) Johnson & Johnson 58 /MA UV blocker (Class 2) Lacreon technology to +6 Low (+0.75 to +1.25) Mid (+1.50 to +1.75) High (+2.00 to +2.50) Intuisight Technology 30-pack/ pack/67.99 Johnson ACUVUE OASYS (2, 3) FOR PRESBYOPIA AIR OPTIX AQUA (2, 3) & Johnson ASTERA Alden Optical UV blocker (Class 1) Hydraclear Plus Technology 33 Aqua Moisture System to Any (14.5 standard) 10 to +6 (0.25 steps) 8.3, 8.6, 8.9 ±30 Low (+0.75 to +1.25) Mid (+1.50 to +1.75) High (+2.00 to +2.50) Lo, Med, High Profile Profile to Profile Zonal aspheric Stereo Precision Technology 6-pack/ pack/53.65 Single/ pack/ (1) Disposable (2) Planned Replacement (3) Extended Wear (EW) Approval (4) Continuous Wear (CW) Approval clspectrum.com/class CONTACT LENSES & SOLUTIONS SUMMARY 15

16 Multifocal Disposable and/or Planned Replacement Hydrogels - continued Trade Name Manufacturer %H 2 O Diameters Base Curves Powers Adds Designs Price BAUSCH + LOMB ULTRA FOR PRESBYOPIA BIOFINITY (2, 3) BIOTRUE ONEDAY FOR PRESBYOPIA (1) C-VUE (2) C-VUE 55 (2) C-VUE ADDVANTAGE C-VUE ADVANCED C-VUE ADVANCED HYDRAVUE C-VUE HYDRAVUE (2) CLARITI 1 DAY (1) DAILIES AQUACOMFORT PLUS DAILIES TOTAL1 FLEXLENS (2) HD (2) HD2 (2) HD DAILIES HDX (2) HDX2 (2) HORIZON BICON HORIZON PROGRESSIVE (2) IDEAL SOFT PS (1, 2) X-Cel (1, 2) X-Cel Bausch + Lomb Bausch + Lomb Unilens Unilens Corp. Unilens Unilens Unilens Unilens 46 Moisture Seal Technology Hypergel UV blocker GMA/ to to to , to , to to , to 16.0 (14.5 to 15.0 std.) 8.0 to 9.5 (8.2, 8.5, 8.8, 9.1 std.) 8.0 to 9.5 (8.2, 8.5, 8.8, 9.1 std.) to Low to +150 High to , +1.50, +2.00, Low: to spectacle add High: to spectacle add C-Vue Low to C-Vue High to C-Vue Low to C-Vue High to C-Vue Low to C-Vue High to to +20 Up to +3 center near 3-Zone design Balanced Design 3-Zone Front aspheric 20 to +20 Up to +4 Front aspheric 6 to D steps to +6 PolyVue PolyVue PolyVue PolyVue PolyVue 33% core 80 surface Water gradient 45, 49, 55, 59, 74 /GMA/ Clear or handling tint , 55, 59, 74 /GMA/ Clear or handling tint 49, 55, 59, 74 /GMA/ Clear or handling tint to to to D steps C-Vue Low to C-Vue High to Low: up to High: up to to Low, medium, high to Front aspheric Center distance Pupil 1, 2, to +6 Up to pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ Trial/ pack/ Trial/ pack/ pack/ pack/ pack/ pack/ pack/ pack/84.00 First lens/ pack/ pack/ Single lens/24.00 Multipack (3+1)/ to +8 Up to pack/ to +6 > 6 and to to +8 Up to pack/ to to to to to to Multi Multi Concentric 14.0 to to to +20 Up to , 8.6, to +9 up to Single lens/24.00 Multipack (3+1)/ pack/39.00 First lens/ pack/ pack/ pack/ First lens/ pack/ pack/ pack/ First lens/ pack/ pack/ FROM THE PUBLISHERS OF CONTACT LENS SPECTRUM

17 Multifocal Disposable and/or Planned Replacement Hydrogels - continued Trade Name Manufacturer %H 2 O Diameters Base Curves Powers Adds Designs Price INTELLIWAVE (2) isight MCL SPHERE METROFOCAL DEFINITIVE NATURALVUE 1 DAY (1) NATURASOFT (2) PROCLEAR 1-DAY Art Optical GP Specialists eering, Inc. Advanced with handling tint 55, Clear or visitint MTO MTO 20 to +20 To to Clear/visitint to to to , 8.6, 8.9 Up to to to D steps One universal add effective up to +3.00D 6.0 to to +30 Up to to +6 Up to PROCLEAR (2) to +6 PROCLEAR XR (2) PUREVISION Bausch (2, 4) MULTI-FOCAL PUREVISION2 MULTI-FOCAL Bausch (2, 4) FOR PRESBYOPIA SATUREYES (2) SOFLENS MULTI-FOCAL (2) SPECIALEYES 54 BIFOCAL SPECIALEYES 54 UCL UCL SONIC-VIEW + Lomb + Lomb Bausch + Lomb SpecialEyes 54 SpecialEyes 54 United United to to to to to to , , to to to to to , 8.7, to , 8.8, to +20 UNILENS EMA (2) Unilens , to +8 (1) Disposable (2) Planned Replacement (3) Extended Wear (EW) Approval (4) Continuous Wear (CW) Approval Daily Wear Spherical Clear and Visibility Tint Hydrogels +1.00, +1.50, +2.00, to +4.00, in to in +3.00, +3.50, Low add to High add to Low: to spectacle add High: to spectacle add up to Low: up to High: to to +25 Up to to +25 Up to Up to Up to EMA Low to EMA High to Front surface aspheric Center distance or Front surface aspheric Center distance Extended depth of focus (distance center) optics Center distance Front surface Concentric Custom zone Center and distance Custom zones & Center distance Front aspheric Trade Name Manufacturer Material %H 2 O Thickness Diameters Base Curves Powers Price ALDEN CLASSIC 38 SPHERE ALDEN CLASSIC 55 SPHERE ALDEN HP 49 SPHERE ALDEN HP 54 SPHERE Alden Optical Alden Optical Alden Optical GMA/ Alden Optical GMA/ to to to to to 9.7 Diagnostic/ pack/ Diagnostic/ pack/90.00 Single/70.90 Spare single/19.99 Spare 3-pack/ pack/71.90 Single/ pack/ pack/ pack/60.00 Trial 10-packs available First lens/ pack/ pack/ pack/ pack/ pack/ pack/ pack/ pack/46.20 Single/ pack/ pack/ ±10.25 to ± ±10.25 to ± ±10.25 to ± ±10.25 to ± Single/ pack vials/ pack vials/ Single/ pack vials/ pack vials/ Replacement / Replacement / pack/ pack/ clspectrum.com/class CONTACT LENSES & SOLUTIONS SUMMARY 17

18 Daily Wear Spherical Clear and Visibility Tint Hydrogels - continued Trade Name Manufacturer Material %H 2 O Thickness Diameters Base Curves Powers Price ALDEN HP 59 SPHERE AQUAEASE Alden Optical GMA/ Ocu-Ease/ GMA/ 6.5 to , 8.5, ±10.25 to ± to to , MTO/ and 4-packs available, call for pricing CONTINENTAL Continental 10.0 to to to , 53 Varies Soft Lens 15.5 to to to +40 to CO SOFT California Optics , 14.5, to 9.2 (0.3) 30 to to DEFINITION WAVETOUCH WaveTouch Soft lens made from in-office patient aberrometry readings ESSTECH SV Blanchard , 8.7, to FLEXLENS LARGE DIAMETER Clear or handling tint 55 Varies 16.1 to to to FLEXLENS PRISM SPHERE /GMA/ Clear or handling tint 45, 49, 55, 59, 74 Varies 13.5 to to 9.2 Custom available of 1.50/ to to +40 Standard/28.00 Custom/50.00 FLEXLENS SPHERE /GMA/ Clear or handling tint 45, 49, 55, 59, 74 Varies 13.5 to to 9.2 Custom available 6.0 to to +40 Standard/28.00 Custom/50.00 FRE-FLEX STANDARD FRE-FLEX SPECIAL DESIGN FRE-FLEX SPECIALTY LENS GELFLEX CUSTOM SPHERE HD Ocu-Ease/ Ocu-Ease/ Ocu-Ease/ Gelflex Laboratories PolyVue to to to to to Varies 10.0 to to to GMA/ 49 /NVP Aqua, blue, 55 chocolate, green , 14.0, 14.5, , 14.3, 14.8, to 9.2 (0.2) 40 to , 8.3, 8.6, 8.9, to to +6 HD DAILIES PolyVue GMA HD2 HORIZON LARGE DIAMETER HORIZON PRISM SPHERE PolyVue Clear or handling tint /GMA/ Clear or handling tint 12 to +6 > 6 and +4 Call for pricing Single lens/24.00 Multipack (3+1)/ pack/ to +8 6-pack/ Varies 16.1 to to to , 49, 55, 59, 74 Varies 13.5 to to / to to HORIZON SPHERE /GMA/ Clear or handling tint 38, 49, 55, 59, 74 Varies 13.5 to to to to +40 Standard/28.00 Custom/50.00 HYDRASOFT IDEAL SOFT INTELLIWAVE ASPHERIC isight SPHERE & GOLD SPHERE (FORMERLY BIOCURVE) KONTUR 55 SPHERE Art Optical , 8.6, 8.9, to , to to Varies , 8.6, 8.9 after with handling tint 49 MTO MTO 20 to +20 GP Specialists to to to +10 Kontur Kontact Lens 55 Varies , 8.6, to pack/54.50 Standard/19.95 Custom/39.95 Diagnostic/35.00 Replacement /25.00 First lens/30.99 Spare lens/ pack/ pack/ FROM THE PUBLISHERS OF CONTACT LENS SPECTRUM

19 Caterer. Runner. Achiever. Because I know Emma s days are demanding, I prescribe ACUVUE OASYS 1-Day. EYE-INSPIRED Design Helps support a stable tear film for exceptional comfort and performance Helps support a stable tear film HydraLuxe Technology: Tear-infused design an enhanced network of tear-like molecules and highly breathable hydrated silicone integrates with your patients tear film each day. for more information visit acuvueprofessional.com The daily lens for demanding days. ACUVUE Brand es are indicated for vision correction. As with any contact lens, eye problems, including corneal ulcers, can develop. Some wearers may experience mild irritation, itching or discomfort. Lenses should not be prescribed if patients have any eye infection, or experience eye discomfort, excessive tearing, vision changes, redness or other eye problems. Consult the package insert for complete information. Complete information is also available by visiting acuvueprofessional.com, or by calling Johnson & Johnson Care, Inc. at ACUVUE, ACUVUE OASYS, EYE-INSPIRED, and HydraLuxe are trademarks of Johnson & Johnson Care, Inc. Johnson & Johnson Care, Inc C June 2017

20 Daily Wear Spherical Clear and Visibility Tint Hydrogels - continued Trade Name Manufacturer Material %H 2 O Thickness Diameters Base Curves Powers Price KONTUR PRECISION Kontur Kontact SPHERE I Lens 55 Varies 12.0 to to to KONTUR PRECISION Kontur Kontact SPHERE II Lens 55 Varies 12.0 to to 9.5 Over ± KONTUR PRECISION Kontur Kontact SPHERE III Lens 55 Varies 18.0 to to 7.5 Plano KONTUR PRECISION Kontur Kontact SPHERE IV Lens 55 Varies 18.0 to to to KONTUR 55 Kontur Kontact SPHERE PRISM Lens 55 Varies 13.0 to to to to 0.25 LL-38 Unilens , 8.6, to to +5 METROLITE of Plano to ± , 8.6, 8.9 Austin Light blue Over ± METROLITE M SERIES of Austin Light blue to Plano METROSOFT II of Plano to ± , 8.6, 8.9 Austin Over ± METROSOFT II of M SERIES Austin to Plano , 14.5, to 8.8 (0.1) 20 to OCU-FLEX-55 /MA Ocu-Ease/ MTO/75.00 available 13.5 to to 9.0 (0.1) to and 4-packs available, call for pricing OPTIMA SP Bausch + Lomb , to plano 2-pack/31.25 PR-46 United Contact Lens , 14.5, , 8.6, 8.9, to SATUREYES of Austin GMA/ 49 Varies , 8.4, SATUREYES of GMA/ VISIBILITY TINT Austin 49 Varies , 8.4, SOF-FORM II Unilens , 8.5, 8.7, to SPECIALEYES 49 SpecialEyes 12.5 to to to to UCL 55% United Contact 14.0, , to to +20 Lens 14.5, , 8.9, UCL CUSTOM UCL TRESOFT United Contact Lens United Contact Lens Extended Wear Spherical Clear and Visibility Tint Hydrogels 16.0, 18.0, 20.0, 22.0, , 9.5, 9.8, 10.0, , , 8.5, to to Trade Name Manufacturer Material %H 2 O Thickness (1) Diameters Base Curves (2) Powers Price ACUVUE 2 ACUVUE OASYS AIR OPTIX AQUA AIR OPTIX NIGHT & DAY AQUA Johnson & Johnson Johnson & Johnson /MA UV blocker (Class 2) UV blocker (Class 1) Hydraclear Plus Technology , , 8.8 Plano bandage lens: 8.4, to +8 beyond ±6 12 to +8 beyond ±6 10 to to to pack/ pack/ pack/ pack/ pack/ , to +8 6-pack/49.70 PUREVISION Bausch + Lomb , 8.6 PUREVISION2 SOFLENS 38 UCL 55 UCL TRESOFT Bausch + Lomb Bausch + Lomb United Contact Lens United Contact Lens to to +6 over to +6 over pack/ pack/ , 8.7, to +4 6-pack/ , 14.5, , 8.6, 8.9, to , , 8.5, to +20 Single/ pack/44.00 Single/ pack/ FROM THE PUBLISHERS OF CONTACT LENS SPECTRUM

21 Therapeutic Spherical Clear and Visibility Tint Hydrogels Trade Name Manufacturer Material %H 2 O Thickness Diameters Base Curves Powers Price ACUVUE OASYS AIR OPTIX NIGHT & DAY AQUA Johnson & Johnson UV blocker (Class 1) Hydraclear Plus Technology , 8.8 Plano bandage lens: 8.4, to +8 above ±6 12-pack/ pack/ , to +6 6-pack/48.50 PUREVISION Bausch + Lomb UCL 55 United Contact Lens Aphakic Spherical Clear and Visibility Tint Hydrogels to to over pack/ Varies 14.0, 14.5, , 8.6, 8.9, to to Trade Name Manufacturer Material %H 2 O Thickness Diameters Base Curves Powers Price AQUAEASE CONTINENTAL PEDIATRIC APHAKIC FLEXLENS PEDIATRIC AND ADULT APHAKIC Ocu-Ease/ GMA/ , 8.5, to Continental 45, 53 Varies 9.5 to to 9.5 Plano to /GMA/ Clear or handling tint 45, 49, 55, 59, 74 Varies Custom available 6.0 to 11.0 Plano to H3 Bausch + Lomb Spin cast to H4 Bausch + Lomb Spin cast to /GMA/ HORIZON PEDIATRIC 45, 49, 55, 59, 74 Varies Custom AND ADULT APHAKIC Clear or handling available tint 6.0 to 11.0 Plano to HYDRASOFT , Varies APHAKIC , 8.6, 8.9, to pack/57.00 IDEAL SOFT isight APHAKIC AND GOLD APHAKIC (FORMERLY BIOCURVE) KONTUR 55 DW APHAKIC NATURASOFT APHAKIC AND PEDIATRIC OCU-FLEX 55 OCU-FLEX 55 PEDIATRIC APHAKIC 38 Varies , 8.6, to +20 after 8.00 GP Specialists to to to +25 Kontur Kontact Lens Advanced Ocu-Ease/ Ocu-Ease/ 55 Varies , to Clear/visitint available to to to , 14.0, 14.5, 15.0, 15.5, , 8.4, 8.6, , 8.5, 8.7, to Varies 8.0 to to to Standard/19.95 Custom/39.95 First lens/50.99 Spare lens/ pack/ pack/71.99 Single/ pack/ pack/ SILSOFT Bausch + Lomb to to 7.9 (0.2) +23 to +32 (3.00D steps) 11.3, to 8.3 (0.2) to +20 () SOF-FORM APHAKIC Unilens , , 8.6, to UCL 55 United Contact Lens 55 Varies 13.0 to to 9.2 Plano to to Special Design Spherical Clear and Visibility Tint Hydrogels Trade Name Manufacturer Material %H 2 O Diameters Base Curves Powers Price CONTINENTAL KERATOCONUS CONTINENTAL KERATOCONUS CONTINENTAL PIGGYBACK CONTINENTAL POSTSURGICAL BANDAGE CONTINENTAL POSTSURGICAL REVERSE GEOMETRY FLEXLENS TRICURVE KERATOCONUS Continental 45, to , 9.8 Any Continental 45, to 16.0 Custom Any power Any axis Continental 45, to 16.0 Any Any Continental 45, , 18.0, 19.0, 20.0, 22.0, to 14.0 Plano Continental 45, to to 9.5 Any /GMA/ Clear or handling tint 45, 49, 55, 59, 74 Custom available 6.0 to to clspectrum.com/class CONTACT LENSES & SOLUTIONS SUMMARY 21

22 Grad student. Volunteer. Value conscious. Whefffouffmoffhfffpfffeffsf feffffouffheffffefhfppfffffare they? Afsfufffoff758fmoffhfffpfffeffsfshowsffhffffwo-fhfffsfexpeffefcef comfoff-fefffefffssuesf*fofffhosefpfffeffs 84 % f COMPENSATE with lens removal, breaks, or rewetting drops 82 % f Feel ANNOYED, INCONVENIENCED or FRfSTRATED 73 % f DON TfPLANfTOfTELL their eye care professional ACfVfEffVITAffBfffffCofffcffLefsesfwefefcfeffeff wffhffhesefpfffeffsffffmffff Supeffoffpfffeffffffffgsffoff OvefffffComfoff f fffweeksf1,f2,f3fffff4fvefsusfafffopffxffaquf,f Bfofffffffffffffffffff Dof ffmfssffhefoppoffuffffffofefevffeffhefexpeffefcefofffouff moffhfffpfffeffsfflefffhemfffffacfvfeffvitafffoffff *Habitual Air Optix Aqua and Biofinity patients who were independently recruited and masked to study sponsor. ACUVUE VITA Brand es are indicated for vision correction as a daily wear lens with one-month recommended replacement. As with any contact lens, eye problems, including corneal ulcers, can develop. Some wearers may experience mild irritation, itching or discomfort. Lenses should not be prescribed if patients have any eye infection, or experience eye discomfort, excessive tearing, vision changes, redness or other eye problems. Consult the package insert for complete information. Complete information is also available by visiting acuvueprofessional.com, or by calling: In Canada: Johnson & Johnson Care division of Johnson & Johnson, Inc. at ; In the US: Johnson & Johnson Care, Inc. at Third-party trademarks used herein are the property of their respective owners. ACUVUE and ACUVUE VITA are trademarks of Johnson & Johnson Care, Inc. Johnson & Johnson Care, Inc B April 2017

23 Special Design Spherical Clear and Visibility Tint Hydrogels - continued Trade Name Manufacturer Material %H 2 O Diameters Base Curves Powers Price FLEXLENS PIGGYBACK FLEXLENS PRS POST REFRACTIVE SURGERY GELFLEX REVERSE GEOMETRY POST SURGICAL Gelflex Laboratories /GMA/ Clear or handling tint /GMA/ Clear or handling tint Custom designed per consult 45, 49, 55, 59, 74 Anterior cutout 6.5mm to 12.5mm Custom available KERASOFT IC Art Optical to 15.5 NATURASOFT IC IRREGULAR CORNEA NATURASOFT IC NATURASOFT IC NATURASOFT ICR IRREGULAR CORNEA REVERSE CURVE NATURASOFT ICR NATURASOFT ICR NATURASOFT PEDIATRIC NOVAKONE KERATOCONUS OCU-FLEX-38 KERATOCONUS REVITALEYES POST-REFRACTIVE SURGERY REVITALEYES DEFINITIVE POST-REFRACTIVE SURGERY AND POST-PKP Advanced Advanced Advanced Advanced Advanced Advanced Advanced Clear/visitint Clear/visitint Clear/visitint Clear/visitint Clear/visitint Clear/visitint Clear/visitint Alden Optical to 11.0 Plano , 49, 55, 59, to to to 9.40 (0.2 steps) Any sphere or cylinder to to to to to to to to +30 Cylinders 0.50 to 15 Axes 1º to 180º (1º steps) 30 to +30 Adds to to to to to to to to to +30 Cylinders 0.50 to 15 Axes 1º to 180º (1º steps) 30 to +30 Adds to to to to +30 (15.0 std.) 5.4 to 8.8 (8.3, 8.6, 8.9 std.) Ocu-ease/ GMA Visitint Clear or visitint , 8.4, 8.7 (equivalents) 7.8, 8.1, 8.4, 8.7 (equivalents) Plano to ± to 10 1º steps 20 to Plano Piggyback custom Any power Sphere or cylinder Any power Sphere or cylinder ROSE K2 SOFT Art Optical to to to +30 SOFT K SPHERE SOFT K SH SOFT K II SH SOFT K II Distributor: Advanced Distributor: Advanced Distributor: Advanced Distributor: Advanced YAMAKONE IC GP Specialists 74 MMA/VP , 7.3, 7.6, 7.9, 8.2 MMA/VP , 7.3, 7.6, 7.9, , , 7.3, 7.6, 7.9, , , 7.3, 7.6, 7.9, to 16.0 Std to to to +10 Cylinders up to 7 Axes 1º to 180º (1º steps) 20 to to +10 Cylinders up to 7 Axes 1º to 180º (1º steps) Diagnostic/120 3-pack/ First lens/ pack/ pack/ First lens/ pack/ pack/ First lens/ pack/ pack/ First lens/ pack/ pack/ First lens/ pack/ pack/ First lens/ pack/130 4-pack/ First lens/ pack/ pack/ Sphere single/ pack/ Toric single/ pack/ Fully warranted Single/ pack/ Diagnostic/ pack/ $ $ Spheres ± Toric ±30.00 Cylinder 0.25 to , any axis First lens/ pack/ pack/ First lens/ pack/ pack/ clspectrum.com/class CONTACT LENSES & SOLUTIONS SUMMARY 23

24 Daily Wear Tinted Enhancer and Opaque Hydrogels Trade Name Manufacturer Material %H 2 O Thickness Diameters Base Curves Powers Price 1-DAY ACUVUE DEFINE AIR OPTIX COLORS ALDEN CLASSIC 38 SPHERE ALDEN HP 49 SPHERE BIOCOLORS EXPRESSIONS HORIZON BICON and BICON HORIZON LARGE DIAMETER HORIZON PEDIATRIC and ADULT APHAKIC HORIZON PRISM SPHERE HORIZON PROGRESSIVE HORIZON PROGRESSIVE HORIZON SPHERE HORIZON METROTINT METROTINT M SERIES OE UNITED COLOR VISION UNITED TRESOFT COLORS Johnson & Johnson Alden Optical Lab Alden Optical Lab Alden Optical Lab/Orion Group of Austin of Austin Ocu-Ease/ United Contact Lens United Contact Lens /MA Peripheral limbal ring tint to clear at center UV blocker (Class 2) Lacreon technology Natural Sparkle, Natural Shimmer, Natural Shine, Accent, Vivid Subtle colors: Pure hazel, blue green, gray, brown Vibrant colors: Honey, brilliant blue, gemstone green, sterling gray Aqua, azure, blue, brown, gray, green, jade, walnut, yellow Aqua, azure, blue, brown, gray, green, jade, walnut, yellow 16 colors Gray, green, hazel, blue, aqua, blue topaz, brown, jade Aqua, blue, green, brown Aqua, blue, green, brown Aqua, blue, green, brown Aqua, blue, green, brown Aqua, blue, green, brown Aqua, blue, green, brown Aqua, blue, green, brown Aqua, blue, green, brown Blue, aqua, green Blue, aqua, green Opaque white Amber, aqua, blue, black, brown, green, orange, red, violet, yellow Enhanced tints Sport tints: Yellow, amber, aqua/teal Special tints: Red for colorblind, purple for migraine headaches Cosmetic enhanced tints: Amber, aqua, blue, brown, red, green, teal, violet, yellow , to to to to to to to 0.75 (0.25 steps) to 0.50 & 6.50 to 9 (including plano in 0.50 steps) 6 to +6 8 to 6 () 30 to to to +30 Cylinder up to 10 Axes up to 180º 30-pack/ pack/ pack/54.00 Standard/50.00 Tint with clear pupil/ Tint with clear pupil/65.00 Sphere/95.00 Toric/ Prosthetic/ to +4 6-pack/ Varies 14.0 to to 9.2 Cylinder 0.50 to 10, Adds to to Varies 16.1 to to to Varies 38, 55 Varies Custom available 13.5 to to to / Varies 14.0 to to Varies 14.0 to to 9.2 Cylinder 0.75 to 5, Adds up to to to , 55 Varies 6.0 to Varies 13.5 to to 9.2 Custom available 6.0 to 11.0 Plano to to , 8.6, to to +20 Adds up to to to to +40 Cylinder 0.50 to 10 Plano to ± Over ± to Plano , 14.5, Plano , , , 8.5, to , to to to +20 Standard/43.00 Custom/65.00 Any UCL lens can be tinted for $40 per lens on top of lens price 24 FROM THE PUBLISHERS OF CONTACT LENS SPECTRUM

25 Daily Wear Tinted Enhancer and Opaque Hydrogels - continued Trade Name Manufacturer Material %H 2 O Diameters Base Curves Spheres Cylinders Axis Ballast Price WESTHIN Customized Tinting Aqua, blue, green, brown 55 Varies 13.5 to to to +20 Cylinder 0.50 to 10 Adventures In Color, Alden Optical, Crystal Reflections, Custom Color, MedCorp International, Orion Group, and Tint provide custom tinting of soft contact lenses for prosthetic and other uses. For specific information, call them. Their telephone numbers and addresses are listed in the company directory on p. 33. Orion Group states that the Chromagen lens is available for certain color deficiencies. It has a 5mm to 7mm tinted optic zone and custom parameters. Call (866) for details. Daily Wear Toric Hydrogels Trade Name Manufacturer Material %H 2 O Diameters Base Curves Spheres Cylinders Axis Ballast Price ALDEN CLASSIC 38 Alden Optical Aqua, azure, blue, brown, gray, green, jade, walnut, yellow GMA/ Visi/clear GMA/ Visi/clear to to to to 10 Any Std. tint/95.00 Tint with clear pupil/80.00 ALDEN HP 49 Alden Any, Any, 8.3, 8.6, 0.25 to 10 Any DES Optical 14.5 std. 8.9 std. 30 to to 10 Any DES ALDEN HP 54 Alden Any, Any, 8.3, 8.6, 54 Optical 14.5 std. 8.9 std. 30 to to 10 Any DES Any, ALDEN HP 59 Alden GMA/ Any, , 8.6, 8.9 Optical Visi/clear 14.5 std. std. 30 to to 10 Any DES AQUAEASE Ocu-Ease/ Any, Any, or GMA/ 49 7 to to 3 Any 14.5 std. 8.2, 8.5, 8.75 slab-off AQUAEASE Ocu-Ease/ Any, Any, or GMA/ to to 6 Any MTO 14.5 std. 8.2, 8.5, 8.75 slab-off BAUSCH + LOMB Bausch + 10º to 180º to plano ULTRA FOR Lomb 1.75, pack/39.50 ASTIGMATISM C-VUE CUSTOM 8.2, 8.5, 8.8, Unilens , to to 5 Any pack/ CONTINENTAL Continental , to to to to 12 Any Soft Lens to CO SOFT FLEXLENS ARC FLEXLENS FRE-FLEX CUSTOM FRE-FLEX SPECIAL DESIGN GELFLEX CUSTOM MTO HD-T HORIZON HYDRASOFT INTELLIWAVE ASPHERIC isight MTO CUSTOM California Optics X-Cel X-Cel Ocu-Ease/ Ocu-Ease/ Gelflex Laboratories PolyVue X-Cel , , 8.9, to to 10 Any /GMA/ Clear or handling tint ; Eccentric lenticulation to to to to to 10 Any , 49, 55, 59, to to to 10 Any Custom available 6.0 to to to 10 Any to to 3 Any Standard/55.00 Custom/ to to to to 16 Any MTO/ , to 9.2 (0.2) 40 to +40 Unlimited Any GMA/ , 14.8, 8.0, 8.3, 8.6, 40 to +40 Unlimited Any /NVP , 9.2 /GMA/ Clear or handling tint to , , 55, 59, Art Optical GP Specialists with handling tint 180º ±20º 90º ±20º 13.5 to to to 10 Any Custom available , , 8.6, 8.9, to to to 10 Any 30 to to 10 Any 74 To MTO MTO 20 to To , º to 180º 1º steps Eccentric lenticulation 13.0 to to to to 8.50 Any Call for pricing Single/24.00 Multipack (3+1)/72.00 Standard/59.00 Custom/ Diagnostic/ Replacement/ clspectrum.com/class CONTACT LENSES & SOLUTIONS SUMMARY 25

26 Daily Wear Toric Hydrogels - continued Trade Name Manufacturer Material %H 2 O Diameters Base Curves Spheres Cylinders Axis Ballast Price KONTUR 55 METROSOFT OCU-FLEX-55 OPTIMA PR-46 SATUREYES SPECIALEYES 49 UCL 55 UCL TRESOFT WESTHIN Kontur Kontact Lens Ocu-Ease/ Bausch + Lomb United SpecialEyes United United X-Cel , 8.6, to to 5 Any , 8.7, 9.0 /MA FROM THE PUBLISHERS OF CONTACT LENS SPECTRUM 14.0, 14.5, 15.0 /NVP , 8.6, to GMA/ Clear or visibility tint 14.0, 14.5, to 5 Any 5.25 to 9 5º steps 8.4 to 9.0 (0.2) 20 to +20 Up to 8 Any 8.0, 8.3, , 9.2, 1.75, 2.25, 2.75, 3.25, 3.75, , to to to , 14.5, to , 8.6, 8.9, 9.2 5º steps Eccentric lenticulation to or slab-off to to +20 Up to 7 Any Any 5º steps to to 8 Any to to 10 Any , , 8.5, to to 7 Any /GMA/ Clear or handling tint Extended Wear Toric Hydrogels 49, 55, 59, to to to to 10 Any Slab-off Slab-off Double slab-off Trade Name Manufacturer Material %H 2 O Diameters Base Curves Spheres Cylinders (1) Axis Ballast Price ACUVUE OASYS FOR ASTIGMATISM Johnson & Johnson UV blocker (Class 1) Hydraclear Plus Technology AIR OPTIX FOR ASTIGMATISM HYDROCURVE 3 PUREVISION PUREVISION2 FOR ASTIGMATISM SOFLENS FOR ASTIGMATISM Bausch + Lomb Bausch + Lomb Bausch + Lomb /Acryl. Clear to +6 9 to 6.50 () 6 to to 6.50 () to (1) All lenses, whether manufactured with front surface toric or back surface toric, are listed in minus cylinder form, as that is how the lenses are ordered. However, we have also indicated by footnotes how they are manufactured. Daily Wear Multifocal Hydrogels 9 to +6 ( above 6.50) 9 to +6 () 9 to +6 ( above 6.50) (2) Manufactured with back toric (3) Manufactured with front toric (4) Custom designs available 1.75, 2.25, , (2) 5º steps 1.75, 2.25, , , 2.25, 2.75 Blink Stabilized Design Precision Balance 8 4 Hybrid Peri and (5) Custom tinting available Trade Name Manufacturer Material %H 2 O Diameters Base Curves Powers Adds Designs Price Johnson & ACUVUE OASYS Johnson FOR PRESBYOPIA AQUAEASE ASTERA BAUSCH + LOMB ULTRA FOR PRESBYOPIA Ocu-Ease/ UV blocker (Class 1) HydraClear Plus Technology Alden Optical 58 Any, 14.5 std. Bausch + Lomb Moisture Seal Technology to +6 Low (+0.75 to +1.25) Mid (+1.50 to +1.75) High (+2.00 to +2.50) Zonal aspheric Stereo Precision Technology , 8.5, to to Any, 8.3, 8.6, 8.9 std. 30 to to +6 Profile 1 2 Profile 2 >2 Low to High to Zone Design Single/ pack/ Nonwarranted/ Nonwarranted/ pack/ pack/40.10 MTO/ pack/ pack/ pack/ pack/26.09 Single/ pack/ pack/52.00

27 Daily Wear Multifocal Hydrogels - continued Trade Name Manufacturer Material %H 2 O Diameters Base Curves Powers Adds Designs Price California Several types of concentric, aspheric, and crescent designs are CO SOFT Optics available. Contact the manufacturer for details. Full parameters DUETTE SynergEyes Hybrid to to +10 on p. 27 DUETTE 10 to Full parameters SynergEyes Hybrid to 8.3 Small or Large on p , +1.75, DUETTE SynergEyes Hybrid to to Full PROGRESSIVE parameters on p. 27 FLEXLENS HD HD DAILIES HD2 HDX HDX2 HORIZON BICON HORIZON PROGRESSIVE INTELLIWAVE IDEAL SOFT PS isight MCL X-Cel PolyVue PolyVue PolyVue PolyVue PolyVue X-Cel X-Cel Art Optical X-Cel GP Specialists /GMA/ Clear or handling tint GMA /GMA/ Clear or handling tint /GMA/ 45, 49, 55, 59, to to to Front aspheric Center distance Pupil 1, 2, to +6 Up to to +6 > 6 and +4 2-pack/ Single/ pack/ Single/ pack/ Single/ Single lens/ Multipack (3+1)/ Up to pack/ to +8 Up to to to +8 49, 55, 59, 74 49, 55, 59, with handling tint 49 Handing tint LL-BIFOCAL Unilens METROFOCAL OCUFLEX 55 Ocu-Ease/ available to to to to to to Multi Multi Concentric 6-pack/ Single lens/ Multipack (3+1)/ pack/ to to to +20 Up to MTO MTO 20 to +20 To , 8.6, to +9 up to , 59, to to to to , only in + 6 to , to (0.50 steps) up to Front surface aspheric Center distance or Concentric Center distance Front aspheric Center distance , 8.4, to to POLYVUE Ideal Optics , to +8 SATUREYES GMA/ , 8.9 SIMULVUE 38 Unilens , to +6 up to up to up to to (2.35, 2.55 seg diam.) Front aspheric Diagnostic/90.00 Replacement/ Front aspheric Center distance Concentric Front aspheric SOFTSITE Unilens , to to SPECIALEYES SpecialEyes to to to Concentric TRITON 38 Gelflex 8.0, 8.2, 8.4, 8.6, TRANSLATING GMA/ , 15.0 Unlimited Translating Call for pricing Laboratories 8.8, 9.0 SOFT BIFOCAL /NVP 55 UNILENS 38 Unilens , 8.7, to United Concentric UCL BIFOCAL , , 8.6, 8.9, to to Replacement/ UCL UCL SONIC VIEW United United , 8.7, to , 8.8, to +20 up to up to Back aspheric Front aspheric Replacement/ Replacement/ clspectrum.com/class CONTACT LENSES & SOLUTIONS SUMMARY 27

28 Extended Wear Multifocal Hydrogels Trade Name Manufacturer Material %H 2 O Diameters Base Curves Powers Adds Designs Price ACUVUE OASYS FOR PRESBYOPIA AIR OPTIX AQUA PUREVISION MULTI-FOCAL Johnson & Johnson Bausch + Lomb PUREVISION2 Bausch + MULTI-FOCAL Lomb FOR PRESBYOPIA UV blocker (Class 1) Hydraclear Plus Technology Aqua Moisture System Multifocal Toric Hydrogels to to to to +6 Low (+0.75 to +1.25) Mid (+1.50 to +1.75) High (+2.00 to Lo, Med, High Low add to High add to Low: to spectacle add High: to spectacle add Zonal aspheric Stereo Precision Technology Front surface aspheric Trade Name Manufacturer Material %H 2 O Diameters Base Curves Spheres Cylinders Adds Design Price ASTERA AQUAEASE CO SOFT 55 C-VUE 55 C-VUE ADVANCED C-VUE HYDRAVUE Alden Optical 54 Any, 14.5 std. Ocu-Ease/ California Optics Any, 8.3, 8.6, 8.9 std. 30 to +30 Up to Profile Profile 2 >+1.75 to Profile pack/ pack/ pack/ pack/44.00 GMA/ , 8.5, to to to , to 9.2 (0.3) 0.75 to to Unilens 55 Unilens GMA/ , 14.5 Unilens , 8.5, to 16.0 (14.5, 15.0 std.) 8.0, 8.2, 8.5, to 9.5 (8.2, 8.5, 8.8, 9.1 std.) 20 to +20 Up to 4 Up to to +20 Up to 4 Up to to +20 Up to 4 Any axis, 1º steps Up to Concentric Front aspheric Front aspheric Front aspheric HD-T Polyvue to , 1.50 Up to 1.00 HDX-T Polyvue to , 1.50 HORIZON BICON HORIZON PROGRESSIVE INTELLIWAVE isight MCL X-Cel X-Cel Art Optical GP Specialists /GMA/ Clear or handling tint /GMA/ Clear or handling tint with handling tint to , 55, 59, to to to to to , 55, 59, to to to to , MTO MTO 20 to +20 Up to 12 1º to 180º 1º steps up to To to to to to to +4 Multi aspheric Concentric Center progressive Front surface aspheric Center distance or Single/ pack/ pack/ pack/ pack/ Trial/ pack/ Trial/20.00 Single/24.00 Multipack (3+1)/72.00 Single/24.00 Multipack (3+1)/ Diagnostic/ Replacement/ Spare single/ Spare 3-pack/56.99 METROFOCAL DEFINITIVE METROFOCAL NATURASOFT Advanced Clear or visitint Clear/visitint , 8.6, to 6 Axis every 5º Up to , to 6 Up to to to to to 15 Axes 1º to 180º (1º steps) Up to Front surface aspheric Center distance Center progressive Single/ pack/ First lens/ pack/ pack/ FROM THE PUBLISHERS OF CONTACT LENS SPECTRUM

29 Multifocal Toric Hydrogels - continued Trade Name Manufacturer Material %H 2 O Diameters Base Curves Spheres Cylinders Adds Design Price OCUFLEX 55 POLYVUE PROCLEAR SATUREYES SPECIALEYES 54 BIFOCAL SPECIALEYES 54 TRITON TRANSLATING BIFOCAL UCL BIFOCAL UCL UCL SONIC VIEW Ocu-Ease/ Ocu-Ease/ , 8.4, to to to to +12 /PC GMA/ SpecialEyes 54 SpecialEyes 54 Gelflex Laboratories United United United 38 GMA/ 49 /NVP 55 Hybrid Soft Skirt/GP Center , to +20 ( after ±6.50) 0.75, 1, 1.75, 2.25 Any axis 0.75 to 5.75 () Low up to High up to , to 6 Up to to to , , to to , 8.2, 8.4, 8.6, 8.8, , 8.6, 8.9, to to 8.00 Up to to to 8.00 Up to +4 Center near MTO/ pack/ pack/ to pack/ Front aspheric Center distance Concentric custom zone Center distance & Custom zones & Center distance Unlimited Unlimited Translating 20 to to , 8.7, to +20 Up to to steps up to , 8.8, to +20 Up to 7 Up to Concentric Back aspheric Front aspheric Trade Name Manufacturer Diameter GP Center Base Curve Power Skirt Curvature Price CLEARKONE SynergEyes 14.5 DUETTE SynergEyes 14.5 DUETTE SynergEyes 14.5 DUETTE PROGRESSIVE SynergEyes 14.5 SYNERGEYES A SynergEyes 14.5 SYNERGEYES KC SynergEyes 14.5 SYNERGEYES SynergEyes 14.5 Segment sizes: 1.9, 2.2 SYNERGEYES PS SynergEyes 14.5 ULTRAHEALTH SynergEyes 14.5 ULTRAHEALTH FC SynergEyes µ to 700µ (50µ steps) 7.1 to to 8.3 (0.2 steps) 7.1 to to to 7.1 (0.2 steps) 7.0 to to 9.0 (0.2 steps) 50µ to 550µ (50µ steps) 55µ to 505µ (50µ steps) 20 to to to Small or large add zone 10 to Add powers: +1.00, +1.75, to +20 Steep2, Steep, Medium, Flat 8.7 (Flat2), 8.4 (Flat), 8.1 (Medium) 8.7 (Flat2), 8.4 (Flat), 8.1 (Medium), 7.9 (Steep) 8.7 (Flat2), 8.4 (Flat), 8.1 (Medium) 1.0, 1.3 Flatter than base (0.7, 1.6 custom, Call for availability) 20 to +8 Steep, medium, flat 20 to +5 Adds: +0.75, +1.25, +1.75, to to to , 1.3 Flatter than base (0.7, 1.6 custom, Call for availability) 8.3, 8.6 Lift: L1 (flat) L2 (medium) L3 (steep) 8.7 (Flat2), 8.4 (Flat), 8.1 (Medium), 7.9 (Steep) 8.4 (Flat), 8.1 (Medium), 7.9 (Steep) Single/ pack/ Single/ pack vials/ pack vials/ Single/ pack vials/ pack vials/ Call for pricing pack/ Single/ pack/ Single/ pack/ Single/ pack/ Single/ pack/ Single/ pack/ Single/ pack/ Single/ pack/ Single/ pack/ Single/ pack/ Single/ Replacement/ Replacement/ clspectrum.com/class CONTACT LENSES & SOLUTIONS SUMMARY 29

30 Gas Permeable Lenses GP General Discussion In the United States, after receiving their FDA Pre-Market Approval (PMA), almost all companies that are PMA holders chose to produce their material in semi-finished buttons which they supply to independent laboratories for custom manufacture and distribution. Because there are more than 300 such laboratories who often affix their own trade name to these lenses, it is neither practical nor useful to list them all. Therefore, we have chosen to provide the basic characteristics of the custom design materials. For specific information on custom-designed lenses, contact your independent laboratory. In this context, custom-designed refers not only to spherical lenses, but also to toric and multifocal lenses. Many independent laboratories are members of the Manufacturers Association. To access addresses, phone number, etc., visit the Gas Permeable Lens Institute s searchable online database: GP Daily Wear Custom Design Materials Trade Name Manufacturer Color Material Dk (1) ACCUCON Inno Clear, blue, gren gray, brown, dark blue Fluorosilicone Acrylate 25 HYDRO2 Soft blue, soft green, ocean blue Fluorosilicone Acrylate 50 ACUITY 18 Acuity Polymers blue, ice blue, green, grey Fluorosilicone Acrylate 18 ACUITY 58 blue, ice blue, green, grey Fluorosilicone Acrylate 58 ACUITY 85 blue, ice blue, green, grey Fluorosilicone Acrylate 85 ACUITY 100 blue, green, ice blue, violet; Fluorosilicone Acrylate 100 Large diameter: Clear, ice blue BOSTON II Bausch + Lomb Clear, blue, green Acrylate 12 (1) BOSTON IV Clear, blue, electric blue Acrylate 19 BOSTON EQUALENS (2) Clear, blue, electric blue Fluorosilicone Acrylate 47 BOSTON ES (2) Blue, ice blue, green, gray, brown, clear Fluorosilicone Acrylate 18 BOSTON EO (2) Blue, ice blue, green, gray, brown, ice green, Fluorosilicone Acrylate 58 electric blue BOSTON EQUALENS II (2) Clear, blue, green, red, yellow Fluorosilicone Acrylate 85 BOSTON XO (2) Blue, ice blue, violet, green, red, yellow, clear Fluorosilicone Acrylate 100 (2) BOSTON XO 2, blue, ice blue, violet, green, Fluorosilicone Acrylate 141 red, yellow FLUOREX 300 (2) G.T. Laboratories Clear, blue, green, gray, aqua, rose brown Fluoro-Silicate Acrylic 30 FLUOREX 500 (2) Clear, blue, green, gray, aqua, rose brown Fluoro-Silicate Acrylic 50 FLUOREX 700 (2) Clear, blue, green, gray, aqua, rose brown Fluoro-Silicate Acrylic 70 FLUOROPERM 30 (2) Paragon Sciences Clear, blue, green, gray, majestic blue, Fluorosilicone Acrylate 30 crystal blue FLUOROPERM 60 (2) Clear, blue, green, brown, crystal blue Fluorosilicone Acrylate 60 FLUOROPERM 92 (2) Clear, blue, green Fluorosilicone Acrylate 92 FLUOROPERM 151 (2) Blue, crystal blue Fluorosilicone Acrylate 151 OPTACRYL 60 Blue Acrylate 18 PARAGON HDS (2) Forest green, emerald green, sapphire blue, Fluorosilicone Acrylate 58 crystal blue PARAGON HDS NON-UV Blue, green Fluorosilicone Acrylate 58 PARAGON HDS 100 (1) Blue, green Fluorosilicone Acrylate 100 PARAGON HDS HI 1.54 Blue, green Fluorosilicone Acrylate 22 PARAPERM O 2 Clear, blue, green, electric blue Acrylate 15.6 PARAPERM EW Clear, blue, green Acrylate 56 PARAGON THIN (2) Blue, green Fluorosilicone Acrylate 29 HYBRID FS Contamac Clear, blue, light blue, green, grey Fluorosilicone Acrylate 31 OPTIMUM CLASSIC (2) Blue, light blue, forest green, green, grey Fluorosilicone Acrylate 26 OPTIMUM COMFORT (2) Blue, brown, forest green, light blue, green, grey Fluorosilicone Acrylate 65 OPTIMUM EXTRA (2) Clear, blue, light blue, green, grey Fluorosilicone Acrylate 100 OPTIMUM EXTREME (2) Blue, green, light blue, grey Fluorosilicone Acrylate 125 OPTIMUM HR 1.51 Blue Fluorosilicone Acrylate 50 OPTIMUM HR 1.53 Blue Fluorosilicone Acrylate 26 OP-2 Stellar Clear, blue, brown, gray, green Fluorosilicone Acrylate 15 OP-3 (2) Blue, brown, gray, green, dark blue, dark green 30 OP-6 (2) Clear, blue, brown, gray, green 60 SGP The LifeStyle Blue, green, brown, gray Siloxane Acrylate 22 SGP II Company Clear, blue, green, brown, gray Siloxane Acrylate 43.5 SGP 3 Clear, blue, green Fluoro-Siloxane Acrylate SA 18 (2) Lagado Corp. Clear, blue, gray, green, brown, Acrylate 18 dark blue, dark green SA 32 (2) Clear, blue, gray, green, brown, Acrylate 32 dark blue, dark green FLOSI (2) Clear, blue, gray, green, brown, Fluorosilicone Acrylate 26 dark blue, dark green ONSI-56 (2) Blue, green, gray, blue-violet, clear Fluorosilicone Acrylate 56 TYRO-97 (2 Clear, blue, green, gray, blue-green Fluorosilicone Acrylate 97 MENICON Z (2,4) Menicon Light blue and clear Fluoro-Siloxanyl Styrene 163 (1) IS0/Fatt method (2) UV absorber/inhibitors available (3) gas-to-gas method (4) Approved for 30-day extended wear 30 FROM THE PUBLISHERS OF CONTACT LENS SPECTRUM

31 GP Extended Wear Custom Design Materials Trade Name Manufacturer Color Material Dk (1) BOSTON EQUALENS (2) Bausch + Lomb Blue Fluorosilicone Acrylate 49 (1) BOSTON EQUALENS II (2) Clear, blue, green Fluorosilicone Acrylate 85 FLUOROPERM 60 (2) Paragon Sciences Clear, blue, green, crystal blue Fluorosilicone Acrylate 60 FLUOROPERM 92 (2) Paragon Sciences (cont'd.) Clear, blue, green Fluorosilicone Acrylate 92 FLUOROPERM 151 (2) Blue, green Fluorosilicone Acrylate 151 PARAGON HDS (2) Forest green, emerald green, Fluorosilicone Acrylate 58 sapphire blue, crystal blue PARAGON HDS 100 Blue, green Fluorosilicone Acrylate 100 PARAPERM EW Clear, blue, green acrylate 56 MENICON Z Menicon Light blue and clear Fluoro-Siloxanyl Styrene 163 (1) IS0/Fatt method (2) UV absorber/inhibitors available. All are FDA approved for 7-day wear. Menicon Z is approved for 30-day wear. Rigid Solutions Major Brand Solutions FUNCTION Manufacturer Solution Wetting Daily Weekly Soaking Cleaning/ Wetting/ Lubricant Preservatives* Approval** Cleaner Cleaner Soaking Soaking ABBOTT Blink X None S.A., F.S.A. MEDICAL OPTICS (AMO) ALCON Clear Care No Rub X None S.A., F.S.A. Clear Care Plus No Rub X X X X None S.A., F.S.A. Clerz Plus Lens Drops X X 2, 7 S.A, F.S.A. Opti-Clean II X 2, 7 S.A., F.S.A Opti-Free Daily Cleaner X 2, 7 S.A., F.S.A SupraClens X None S.A., F.S.A. BAUSCH + Boston Original Formula Cleaner X None S.A. LOMB F.S.A. Boston Original Formula X X X 2, 6 S.A. Conditioning Solution F.S.A. Boston Advance Cleaner X None S.A. F.S.A. Boston Advance Comfort X 2, 6, 11 S.A. Formula Conditioning Solution F.S.A. Boston Rewetting Drops X 2, 6 S.A. F.S.A. Boston Simplus Multi-Action X X X X X X 6, 11 S.A. Solution F.S.A. Boston One Step Liquid X None S.A. Enzymatic Cleaner F.S.A. PeroxiClear X None S.A., F.S.A. Wetting & Soaking Solution X 2, 6 S.A., F.S.A., P.M.M.A. CONTEX Clear/Clean X X X None S.A., F.S.A. Polish Brite X None S.A., F.S.A. LOBOB Cleaner X -- P.M.M.A. Optimum Extra Strength Cleaner X -- S.A., F.S.A. Soaking Solution X 2, 3 P.M.M.A. * PRESERVATIVES ** APPROVALS 1 = Thimerosal 6 = Chlorhexidine 10 = Potassium Sorbate S.A. = Siloxane acrylates 2 = Edetate Disodium 7 = Polyquad 11 = Polyaminopropyl Biguanide F.S.A. = Fluoro-siloxane acrylate 3 = Benzalkonium Chloride 8 = Chlorobutanol 12 = Benzyl Alcohol P.M.M.A. = Polymethyl-methacrylate 4 = Boric Acid 9 = Phenylmercuric Nitrate 13 = Polixetonium Chloride 5 = Sorbic Acid clspectrum.com/class CONTACT LENSES & SOLUTIONS SUMMARY 31

32 Major Brand Solutions - continued FUNCTION Manufacturer Solution Wetting Daily Weekly Soaking Cleaning/ Wetting/ Lubricant Preservatives* Approval** Cleaner Cleaner Soaking Soaking LOBOB (cont'd.) Optimum Wetting/Rewetting Drop X X 12 S.A., F.S.A Wetting Solution X 2, 3 P.M.M.A Optimum Cleaning, Disinfecting, Storage X X 12 S.A., F.S.A. MENICON LacriPure None Progent Protein Remover X None S.A., F.S.A. Unique ph X X X X X X 7 S.A., F.S.A. OPTIKEM INT L Sereine Wetting X 3, 2 P.M.M.A. Sereine Cleaning X 3, 2 S.A., F.S.A. Sereine Soaking/Cleaning X 3, 2 P.M.M.A. Con-Sure Cleaning (lab strength) X P.M.M.A. Sereine Wetting/Soaking X 3, 2 S.A., F.S.A. * PRESERVATIVES ** APPROVALS 1 = Thimerosal 6 = Chlorhexidine 10 = Potassium Sorbate S.A. = Siloxane acrylates 2 = Edetate Disodium 7 = Polyquad 11 = Polyaminopropyl Biguanide F.S.A. = Fluoro-siloxane acrylate 3 = Benzalkonium Chloride 8 = Chlorobutanol 12 = Benzyl Alcohol P.M.M.A. = Polymethyl-methacrylate 4 = Boric Acid 9 = Phenylmercuric Nitrate 13 = Polixetonium Chloride 5 = Sorbic Acid Soft Solutions Non-Thimerosal Preserved Saline Manufacturer Trade Name Formulation Clear Care Rinse & Go A sterile, isotonic, buffered saline solution containing sodium chloride, citrate, citric acid, 0.05% edetate disodium, and preserved with 0.001% Polyquad (polyquaternium-1). Clear Care Rinse & Go is not a contact lens cleaning and disinfecting solution and should not be used for that purpose Bausch + Lomb Sensitive Eyes Saline Solution A sterile, isotonic, buffered solution containing boric acid, sodium borate and sodium chloride; preserved with sorbic acid 0.1% and edetate disodium 0.025% Sensitive Eyes Plus Saline Solution A sterile, isotonic, buffered solution containing boric acid, sodium borate, potassium chloride, sodium chloride; preserved with polyaminopropyl biguanide %, and edetate disodium 0.025% Unpreserved Saline Manufacturer Trade Name Formulation The Lifestyle Company PuriLens Plus Isotonic, buffered saline in 4 oz. bottles Menicon LacriPure Sterile normal saline in 5mL unit dose vials Daily Cleaners Manufacturer Trade Name Formulation Opti-Clean II A sterile, isotonic formulation containing Tween 21 and special polymeric cleaning agents preserved with 0.1% edetate disodium and 0.001% Polyquad (polyquaternium-1) Opti-Free Daily Cleaner A sterile, isotonic, buffered formulation containing Tween 21 and micro-lens beads and preserved with 0.1% edetate disodium and 0.001% Polyquad (polyquaternium-1) Bausch + Lomb Sensitive Eyes Daily Cleaner Easy-rinsing formula with balanced viscosity, containing poloxamine, a borate buffer system sodium chloride, hydroxypropyl-methylcellulose, preserved with edetate disodium 0.5% and sorbic acid 0.25% Lobob Sof/Pro2 SiHy Extra Strength Daily Cleaner Isopropyl alcohol and surfactants; preservative-free Optikem International Sereine Extra Strength Daily Cleaner Preservative-free; containing isopropyl alcohol and surfactants 32 FROM THE PUBLISHERS OF CONTACT LENS SPECTRUM

33 Weekly Cleaners (Protein Removers) Manufacturer Trade Name Formulation Abbott Medical Ultrazyme Enzymatic Cleaner Subtilisin A; for use directly in a 3% hydrogen peroxide disinfection solution Optics (AMO) Daily Protein Removers Manufacturer Trade Name Formulation Opti-Free Supraclens Daily Protein Remover A preservative-free solution containing propylene glycol, sodium borate and highly purified pancreatin Disinfecting Solutions and Combinations Manufacturer Trade Name Formulation Abbott Medical Blink RevitaLens Multi-Purpose A sterile, buffered aqueous solution with alexidine dihydrochloride % and polyquaternium % Optics (AMO) Disinfecting Solution as preservatives/disinfectants, boric acid, sodium borate, Tetronic 904, edetate disodium, sodium citrate, sodium chloride, and purified water Complete MPS Easy Rub Formula A sterile, isotonic, buffered solution, preserved with polyhexamethylene biguanide (0.0001%), a phosphate buffer, Poloxamer 237, edetate disodium, sodium chloride, potassium chloride, and purified water. Complete Multi- Purpose Solution contains no chlorhexidine or thimerosal Opti-Free Express MPDS A sterile, buffered, isotonic aqueous solution containing sodium chloride, sodium citrate, boric acid, sorbitol, Tetronic 1304, aminomethylpropanol, edetate disodium 0.05%, and preserved with 0.001% Polyquad (polyquaternium-1) and % Aldox (myristamidopropyl dimethylamine) Opti-Free PureMoist MPDS Opti-Free Replenish Multi-Purpose Disinfecting Solution A sterile, buffered, isotonic aqueous solution containing sodium chloride, sodium citrate, boric acid, sorbitol, aminomethylpropanol, edetate disodium, two wetting agents (Tetronic 1304 and HydraGlyde Moisture Matrix [EOBO-41 polyoxyethylene-polyoxybutylene]) and preserved with 0.001% Polyquad (polyquaternium-1) and % Aldox (myristamidopropyl dimethylamine) A sterile, buffered, isotonic aqueous solution to clean, rinse, disinfect, store, and recondition silicone and soft contact lenses. Contains sodium chloride, sodium citrate, sodium borate, propylene glycol, TearGlyde (Tetronic 1304 and C9ED3A), and preserved with 0.001% Polyquad (polyquaternium-1) and % Aldox (myristamidopropyl dimethylamine) Bausch + Lomb Biotrue Multi-Purpose Solution A sterile, isotonic solution that contains hyaluronan, sulfobetaine, poloxamine, boric acid, sodium borate, edetate disodium and sodium chloride, preserved with a dual disinfection system (polyaminopropyl biguanide % and polyquaternium %) Renu Advanced Formula Multi-Purpose Solution Sterile isotonic solution containing poloxamine, poloxamer 181, diglycine, sodium citrate, boric acid, sodium borate, edetate disodium, and sodium chloride and preserved with a triple disinfectant system (polyaminopropyl (polyaminopropyl biguanide %, polyquaternium % and alexidine %) Lite Solution A sterile, isotonic solution that contains poloxamer, sodium phosphate buffer, sodium chloride, and disodium Multipurpose Solution edetate; preserved with polyhexanide %. Contains no chlorhexidine or thimerosal Hydrogen Peroxide Disinfection Manufacturer Trade Name Formulation Abbott Medical The Oxysept UltraCare Formula Oxysept disinfecting solution: Microfiltered Hydrogen peroxide 3% (stabilized with sodium stannate and sodium Optics (AMO) Disinfecting/Neutralizer nitrate, and buffered with Phosphates) and purified water in a preservative-free, sterile solution clspectrum.com/class Oxysept neutralizing tablets: Smooth, round, tablets that contain catalase, hydroxypropyl methylcellulose, and cyanocobolomine (vitamin B 12 ) with buffering and tableting agents Oxysept Cup: A specifically designed lens cup that must be used with the UltraCare system. It consists of a single flared cup and a lens holder attached to the cap. The left lens basket and the gasket inside the top of the cap are blue. This will distinguish this cup from other lens cases Clear Care No Rub A cleaning and disinfection solution (red tip) containing 3% hydrogen peroxide (stabilized with phosphonic acid), 0.79% sodium chloride, phosphate buffered with Pluronic 17R4 (a cleaning agent). One solution for cleaning, disinfecting, and removal of protein for all soft contact lenses Disposable cup/disc packaged with product Clear Care Plus Disposable cup/disc packaged with product Specially designed cup provided with Clear Care Disinfecting Solution with platinum coated catalytic plastic disc used for automatic neutralization of hydrogen peroxide A cleaning and disinfection solution (red tip) containing 3% hydrogen peroxide (stabilized with phosphonic acid), 0.79% sodium chloride, phosphate buffered with Pluronic 17R4 (cleaning agent) and containing wetting agent HydraGlyde Moisture Matrix EOBO-21 (polyoxyethylene-polyoxybutylene). One solution for cleaning, disinfecting, removal of protein, and improved wettability for all soft lenses Specially designed cup provided with Clear Care Disinfecting Solution with platinum coated catalytic plastic disc used for automatic neutralization of hydrogen peroxide Bausch + Lomb PeroxiClear Solution 3% hydrogen peroxide cleaning and disinfecting solution with a phosphonic acid stabilizer, potassium chloride, propylene glycol, carbamide, poloxamer 181, citrate and phosphate buffers. Preservative free Package includes special lens case with neutralizing disc OcuSoft Ocusoft Lens Care System Sterile, preservative-free solution containing hydrogen peroxide 3% stabilized with phosphonic acid and buffered with phosphates Refine One Step: One step, preservative-free cleaning and disinfecting solution with 3% hydrogen peroxide with lubricating agent 3% hydrogen peroxide cleaning for enhanced lens wearing comfort and disinfecting lens care system CONTACT LENSES & SOLUTIONS SUMMARY 33

34 Subsonic/UVC Disinfection Manufacturer Trade Name Formulation The LifeStyle PuriLens Plus Unit 15-minute automatic cleaning and disinfecting system. Subsonic agitation creates hydrodynamic shear to clean Company lenses. UVC light cross-links DNA in microorganisms or cells and causes instant death Lubricants/Rewetting Drops Manufacturer Trade Name Formulation Abbott Medical Blink Lubricant Eye Drops A sterile, buffered, isotonic, preserved solution. This aqueous formulation includes purified water, sodium Optics (AMO) hyaluronate, sodium chloride, potassium chloride, calcium chloride, magnesium chloride, boric acid and is preserved with OcuPure (stabilized oxychloro complex) 0.005%. This preparation contains no chlorhexidine, no thimerosal, and no other mercury containing ingredients Akorn TheraTears Comfort Drops Contains carmellose sodium in purified water as a lubricant. It is a sterile, hypotonic, borate buffered solution containing sodium chloride, potassium chloride, sodium bicarbonate, calcium chloride, magnesium chloride, and sodium phosphate. The preservative system consists of sodium perborate stabilized with phosphonic acid. Contains no chlorhexidine, no thimerosal, and no other mercury-containing ingredients, and it contains no detergents Allergan Refresh Sterile, isotonic, buffered, preserved solution containing carboxymethylcellulose sodium, sodium chloride, boric acid, potassium chloride, calcium chloride, magnesium chloride, purified water and is preserved with Purite (stabilized oxychloro complex) Clerz Plus Lens Drops A rewetting and lubricating drop that fights protein buildup during lens wear. A sterile, isotonic formulation containing a citrate/borate buffer, sodium chloride, mannitol, RLM 100 (PEG-11 lauryl ether carboxylic acid), tetronic 1304, edetate disodium, and 0.001% Polyquad (polyquaternium-1) Opti-Free Express Rewetting Drops A sterile, isotonic, buffered saline solution containing sodium chloride, citrate, citric acid, 0.05% edetate disodium and preserved with 0.001% Polyquad (polyquaternium-1) Opti-Free PureMoist Rewetting Drops A rewetting and lubricating lens drop that fights protein buildup during lens wear. A sterile, Isotonic formulation containing a citrate/borate buffer, sodium chloride, mannitol, RLM 100 (PEG-11 lauryl ether carboxylic acid), tetronic 1304, edetate disodium, and 0.001% Polyquad (polyquaternium-1) Opti-Free Replenish Rewetting Drops A rewetting and lubricating lens drop that fights protein buildup during lens wear. A sterile, isotonic formulation containing a citrate/borate buffer, sodium chloride, mannitol, RLM 100 (PEG-11 lauryl ether carboxylic acid), tetronic 1304, edetate disodium, and 0.001% Polyquad (polyquaternium-1) Opti-Free Pro Moisturizing Lens Drops Opti-Free Pro Lubricating Eye Drops A lens drop to moisturize, lubricate, cushion, and provide enhanced lubrication to the contact lens while being worn. Opti-Free Pro Moisturizing Drops can be used with all silicone and soft (hydrophilic) contact lenses, including daily wear and disposable. A sterile, buffered, aqueous solution containing two demulcents 0.4% PEG400 and 0.3% propylene glycol with sodium chloride, potassium chloride, sodium borate, sorbitol, aminoethylpropanol, HP-Guar, and preserved with Polyquad (polyquaterrnium-1) A sterile, buffered, aqueous lubricating eye drop that contains the demulcent propylene glycol 0.6%, with boric acid, dimyristoyl phosphatidylglycerol, edetate disodium, hydroxypropyl guar, mineral oil, polyoxyl 40 stearate, sorbitan tristearate, sorbitol, purified water, and preserved with 0.001% Polyquad (polyquaternium-1) Bausch + Lomb ReNu Rewetting Drops Sterile, buffered, isotonic, solution that contains boric acid, poloxamine, sodium borate, and sodium chloride; preserved with sorbic acid 0.15% and edetate disodium 0.1% ReNu MultiPlus Lubricating and A sterile, isotonic solution that contains povidone, boric acid, potassium chloride, sodium borate and sodium Rewetting Drops chloride; preserved with edetate disodium 0.1% and sorbic acid 0.1% Sensitive Eyes Drops Sterile, buffered, isotonic aqueous solution, and sodium chloride preserved with sorbic acid 0.1% and edetate disodium 0.025% 34 FROM THE PUBLISHERS OF CONTACT LENS SPECTRUM

35 Company Directory Acuity Polymers, Inc Lake Avenue Building 59, Suite 303 Rochester, NY (888) POLYMER ( ) Adventures In Color 1800 Jackson St. Suite 204 Golden, CO (303) (800) FAX (303) Abbott Medical Optics (AMO) 1700 E. St. Andrew Place Santa Ana, CA (714) (866) Advanced 969 S. Kipling Parkway Lakewood, CO (888) FAX (303) Akorn Consumer Health 2929 Plymouth Rd. Suite 275 Ann Arbor, MI (734) FAX (734) Laboratories 6201 South Freeway Ft. Worth, TX (817) (800) Alden Optical 6 Lancaster Pkwy. Lancaster, NY (800) FAX (800) Art Optical, Inc. P.O. Box 1848 Grand Rapids, MI Customer Care: (800) Consultation: (800) FAX (800) Bausch + Lomb 1400 N. Goodman St. Rochester, NY (800) FAX (800) Blanchard, Inc South Willow Building #2 Manchester, NH (800) FAX (603) California Optics Golden Springs Dr. #348 Diamond Bar, CA (800) FAX (909) Clearlab 4200 Jenkins Ct. Suwanee, GA (888) FAX (770) Contamac US, Inc. 806 Kimball Ave. Grand Junction, CO (970) (866) FAX (970) Contex Inc Van Nuys Blvd. Sherman Oaks, CA Consultation: (818) Customer Service: (800) FAX (818) Continental Soft Lens P.O. Box Littleton, CO (800) (303) FAX (303) High Point Dr. Suite 100 Victor, NY (800) Crystal Reflections 170 N. La Canada Suite 80 Green Valley, AZ (800) FAX (520) Custom Color 55 West 49th St. New York, NY (800) G.T. Laboratories, Inc Warrenville Rd. Suite 200 Lisle, IL (800) FAX (847) Gelflex USA 144 Old Brookfield Rd. Danbury, CT (203) (866) GELFLEX ( ) FAX (203) GP Specialists Bernardo Center Dr. San Diego, CA (800) (800) FAX (800) Inno 3125 South 61st Ave. Omaha, NE (800) Johnson & Johnson 7500 Centurion Pkwy. Jacksonville, FL (800) FAX (800) Kontur Kontact Lens 642 Alfred Noble Dr. Hercules, CA (800) FAX (800) Lagado Corp S. Tejon St. Englewood, CO (303) (800) FAX (303) LifeStyle Co., Inc. 6 Paragon Way Suite 112 Freehold, NJ (800) FAX (732) Lobob Laboratories 1440 Atteberry Lane San Jose, CA (800) (408) FAX (408) Menicon America 76 Treble Cove Rd. Building 3 North Billerica, MA (800) FAX (781) P.O. Box Austin, TX (800) (512) FAX (512) Ocu-Ease/ Optical Products 920 San Pablo Ave. Pinole, CA (800) FAX (800) OcuSoft, Inc Southwest Freeway Rosenberg, TX (800) FAX (281) Optical Connection Int'l, Inc Bernardo Center Dr. San Diego, CA (888) FAX (866) Optikem International 2172 S. Jason St. Denver, CO (800) FAX (303) Paragon Sciences 947 E. Impala Mesa, AZ (800) PolyVue 3610 Ocean Ranch Blvd. Oceanside, CA (877) FAX (760) SpecialEyes, LLC P.O. Box Bradenton, FL (866) FAX (866) ) Tint 1835A S. Centre City Pkwy. Suite 501 Escandido, CA (800) FAX (760) Stellar, Inc Province Circle Mundelein, IL (224) FAX (847) SynergEyes, Inc Priestly Dr. Suite 210 Carlsbad, CA (877) SEE-2012 FAX (877) Unilens Corp. U.S.A nd St. North Largo, FL (727) (800) FAX (800) United st Ave. NE Unit #5 Arlington, WA (206) (800) FAX (888) eering, Inc Mansell Rd. Suite 300 Alpharetta, GA (844) VTI-LENS ( ) FAX (877) Premiere Pkwy. Suite 600 Duluth, GA (800) FAX (770) (formerly Hydrogel Corp.) 7575 Commerce Ct. Sarasota, FL (877) (888) Rigid Gas Permeable Lens Institute s searchable online database: clspectrum.com/class CONTACT LENSES & SOLUTIONS SUMMARY 35

36 Editor. Foodie. Comfort Seeker. Because I know Maria s vision is changing, I prescribe 1-DAY ACUVUE MOIST Brand. EYE-INSPIRED Design Pupil optimization for the presbyopic eye PUPIL SIZE VARIES BY AGE AND REFRACTIVE POWER Youth Adult Mature Presbyope Myope Emmetrope Hyperope INTUISIGHT Technology uniquely optimizes the optical design to the pupil size for predictable performance across the refractive range and ADD powers. For illustrative purposes only. OPTICAL DESIGN Competitive lens designs: fixed optical design for more information visit acuvueprofessional.com The ONLY multifocal lens with pupil optimization from the #1 selling daily disposable contact lens brand in the world* * Source: Euromonitor International Limited; based on research conducted from December 2015 to February 2016; world and globally represent markets accounting for 75% of total daily disposable contact lenses in 2014 (retail sales). ACUVUE Brand es are indicated for vision correction. As with any contact lens, eye problems, including corneal ulcers, can develop. Some wearers may experience mild irritation, itching or discomfort. Lenses should not be prescribed if patients have any eye infection, or experience eye discomfort, excessive tearing, vision changes, redness or other eye problems. Consult the package insert for complete information. Complete information is also available by visiting acuvueprofessional.com, or by calling Johnson & Johnson Care, Inc. at ACUVUE, 1-DAY ACUVUE MOIST, EYE-INSPIRED, and INTUISIGHT are trademarks of Johnson & Johnson Care, Inc. Johnson & Johnson Care, Inc March 2017