Unique Aberration-Free IOL: A Vision that Patients

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Theodore Chase
5 years ago
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1 Unique Aberration-Free IOL: A Vision that Patients Can Appreciate

2 An Aspheric Optic for Improved Quality of Vision n Traditional spherical IOLs create Bilateral implantation study spherical aberration and reduce contrast sensitivity High Order Aberrations at months: 6mm pupil n With, unique aspheric 2. anterior and posterior surfaces are aberration neutral n The result? Clinical outcomes.86 Total HOA 1.4 demonstrate a reduction in overall higher order aberrations 1 coma SA 1. n Contrast sensitivity under photopic.6.8 or mesopic lighting conditions is similar to silicone aspheric aberrated IOL Akreos Adapt (n=2) Akreos Adapt AO (n=2) G. Lofoco. Influence of Aspheric and Spherical IOLs on Higher-Order Aberrations and Functional Vision: Results of a Comparative Multi-center Study. ASCRS Bilateral implantation study Mesopic Contrast Sensitivity: cd/m Contrast Sensitivity Contrast Sensitivity Photopic Contrast Sensitivity: 85 cd/m , ,5 Spatial Frequency (CPD) (n=8) Spatial Frequency (CPD) Silicone Aspheric Aberrated IOL (n=8) B. Johansson et al. Swedish multi-center study to compare the optical performance of the Akreos Adapt Advanced Optic (AO) IOL and the Tecnis Z9. ASCRS 26. 2

3 Uniform Power Designed to Work in Every Eye n No eye is optically perfect The Natural Phakic Eye n Constant power from centre to edge helps to improve vision by providing consistent power across the entire optic surface Iris n is designed to provide OPTICAL AXIS (Cornea to Lens) predictable, repeatable refractive outcomes for all cataract patients, regardless of corneal shape, pupil size, as well as pupil or capsular bag centration VISUAL AXIS (Object to Fovea) Fovea Lens n Clinical results show excellent high Retina and low contrast BCVA comparable to a middle-age phakic eye All axes in the eye are not perfectly aligned and no two eyes are the same shape so you need IOLs that work with imperfect conditions. BCVA compared to phakic eyes. 2/4..2 2/ /25.1 2/4 patients (mean age: 7-year-old) patients (mean age: 7-year-old) 2/2 2/ IogMar IogMar 6 months 2/2 Normal phakic population (mean age: 4-year-old) 6 months 1 year -.1 2/ /2 Normal phakic population (mean age: 4-year-old) 2/ High Contrast (n=5) 1 year Low Contrast (n=5) V. Pfeifer. Clinical evaluation of a new aspheric IOL: the Akreos Adapt Advanced Optics (AO). Data from a pilot study at six months follow up. ASCRS 26.

4 Aberration-Free Design Helps to Enhance Depth of Field n The phakic eye has some natural level of positive spherical aberration n Positive spherical aberration helps the phakic eye achieve better depth of field n maintains the natural, positive spherical aberrations compared to aspheric, aberrated IOLs 2 (top figure) n With its aberration-free design, helps to significantly improve depth of field in comparison to an aspheric aberrated IOL2 (bottom figure) Natural Functionality Bilateral implantation study Spherical Aberrations Depth of focus in intermediate vision 1 Silicone Aspheric Aberrated IOL,8 RMS,6,4,2 -.2 Z4 4mm Z4 4,5mm Corneal Peripheral rays Mean Depth of Field4 p=, Corneal Medium rays Number of patients Z4 5mm Silicone Aspheric Aberrated IOL.85 Dpt.71 Dpt Corneal Central rays In intermediate vision more distant objects are seen through central corneal rays whereas closer objects are seen through peripheral corneal rays Johansson et al. Swedish multi-centre study to compare the optical performance of B the Akreos Adapt Advanced Optic (AO) IOL and the Tecnis Z9. ASCRS 26. Measured with the Strehl ratio as described by S. Marcos et al. Implantation of Spherical and Aspheric IOLs. Journal of Refractive Surgery. May June 25; 21:1 1. 4

5 A Visual Difference Patients Appreciate n A masked, subjective patient n Patients had no way of knowing assessment following cataract surgery showed that twice as many patients prefer the vision in their eye2 (left figure) which lens was implanted in their eyes n Patients also reported fewer visual disturbances in their eye compared to the silicone aspheric aberrated IOL eye2 (right figure) Bilateral implantation study: double-masked questionnaire Any preference for one eye Less dysphotopsia in one eye % 1 Silicone Aspheric Aberrated IOL 14% 1 No difference 58% (n=8) 2 % Silicone Aspheric Aberrated IOL 11% No difference 56% (n=55) B. Johansson et al. Swedish multi-centre study to compare the optical performance of the Akreos Adapt Advanced Optic (AO) IOL and the Tecnis Z9. ASCRS 26. 5

For Optimised Effectiveness against PCO n The unique Square-Edge Technology and a 6 posterior

the design is in blocking cell growth n Results are comparable to the best performing acrylic

48.48 mm central area.7.8.12 (n=42) (n=48) (n=41) EPCO Scores @ 12 months Limit at which PCO

Nd:Yag capsulotomy usually performed beyond.5 to 1.

6 For Optimised Effectiveness against PCO n The unique Square-Edge Technology and a 6 posterior barrier reduce cell migration following implantation n EPCO analysis shows just how effective the design is in blocking cell growth n Results are comparable to the best performing acrylic IOLs5 Akreos Advanced Optics EPCO months 6mm optic area mm central area (n=42) (n=48) (n=41) EPCO 12 months Limit at which PCO does not require Nd:Yag capsulotomy* One-Piece Hydrophobic Acrylic Lens mm optic area (n=41) mm central area (n=41) 6mm optic area (n=12) mm central area (n=12) * Nd:Yag capsulotomy usually performed beyond.5 to 1., depending on PCO location and patient s complaint. 5 V. Pfeifer. Clinical evaluation of a new aspheric IOL: the Akreos Adapt Advanced Optics (AO). Data from a pilot study at six months follow up. ASCRS 26. Data on file. 6

Efficient Implantation through an Unenlarged Phaco Incision n The Akreos Single-Use Insertion

8mm phaco incision n Improved plunger design provides symmetrical unfolding and easier

makes quick work of lens implantation Single-Use Lens Delivery System Akreos Single-Use

7 Efficient Implantation through an Unenlarged Phaco Incision n The Akreos Single-Use Insertion Device enables implantation of the through a 2.8mm phaco incision n Improved plunger design provides symmetrical unfolding and easier placement of the lead haptics into the capsular bag n The flat loading, single-hand injection makes quick work of lens implantation Single-Use Lens Delivery System Akreos Single-Use Insertion Device AI-28B 1. Place the lens flat in to the loading deck 2. Close the injector and fit the tip 7. Advance the plunger and deliver the lens

$Akreos Advanced Optics System Model: Adapt AO DIOPTER RANGE:. through 9. in 1. Dpt MATERIAL: 26% acrylic material, 1. through. in.5 Dpt UV absorber, Refractive index: 1.$ 22 1.4 HAPTICS: ORDER CODES: One-piece, º angulation Lens in plastic vial: ADAPTAOP or ADAPTAOTP OVERALL DIAMETER: 11.mm from. to 15. Dpt 1.7mm from 15.5 to 22.

22 1.4 HAPTICS: ORDER CODES: One-piece, º angulation Lens in plastic vial: ADAPTAOP or ADAPTAOTP OVERALL DIAMETER: 11.mm from. to 15. Dpt 1.7mm from 15.5 to 22.

Dpt Belgium/Luxembourg Tel: +2 28 82 4 Fax: +2 28 82 59 Germany/ Switzerland/Austria Tel: +49 9 541 Fax: +49 9 547 Portugal Tel: +51 88 2 178 Fax: +51 88 2 179

655 464 Tel: +4 92 81 1 Fax: +4 92 25 1 South Africa Tel: +46 8 616 95 Fax: +46 8 669 86 2 Tel: +27 11 259 26 Fax: +27 11 259 265 United Kingdom Tel: +44 2 8781

Bausch & Lomb European Office, Bausch + Lomb House, 16 114 London Road, Kingston-upon-Thames, Surrey KT2 6TN, UK. Tel: +44 2 8781 55 Fax: +44 2 8781 299 www.

8 Akreos Advanced Optics System Model: Adapt AO DIOPTER RANGE:. through 9. in 1. Dpt MATERIAL: 26% acrylic material, 1. through. in.5 Dpt UV absorber, Refractive index: (hydrated) LENS CONSTANTS: OPTIC: A-Constant* (SRK/T) Biconvex aspheric anterior and posterior, Optic body: 6mm ACD* Surgeon Factor* HAPTICS: ORDER CODES: One-piece, º angulation Lens in plastic vial: ADAPTAOP or ADAPTAOTP OVERALL DIAMETER: 11.mm from. to 15. Dpt 1.7mm from 15.5 to 22. Dpt Applanation Immersion A-scan A-scan or IOL Master* Injector: AI-28B 1.5mm from 22.5 to. Dpt Belgium/Luxembourg Tel: Fax: Germany/ Switzerland/Austria Tel: Fax: Portugal Tel: Fax: Emerging Markets Tel: Fax: Italy Tel: Spain Netherlands France Tel: Fax: Tel: Fax: Tel: Fax: South Africa Tel: Fax: Tel: Fax: United Kingdom Tel: Fax: Nordic Countries For information or Customer Service please contact your local representative or distributor. Bausch & Lomb European Office, Bausch + Lomb House, London Road, Kingston-upon-Thames, Surrey KT2 6TN, UK. Tel: Fax: Bausch & Lomb Incorporated / March211 / version 2 / / denote trademarks of Bausch & Lomb Incorporated * A-Constant, ACD and Surgeon Factor are estimates only. Latest update March 211. It is recommended that each surgeon develop his or her own values.

Not everyone can do this. Introducing RayOne with patented Lock & Roll TM technology for the smallest fully preloaded IOL incision

Not everyone can do this. Introducing RayOne with patented Lock & Roll TM technology for the smallest fully preloaded IOL incision Not everyone can do this Introducing RayOne with patented Lock & Roll TM technology for the smallest fully preloaded IOL incision RayOne fully preloaded IOL injection system, designed to deliver without