2018 INTERNATIONAL SYMPOSIUM ON THE FRONTIERS AND PRACTICE OF INNOVATIVE DRUG DISCOVERY
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1 Updated on July 24, INTERNATIONAL SYMPOSIUM ON THE FRONTIERS AND PRACTICE OF INNOVATIVE DRUG DISCOVERY THE 8 TH INTERNATIONAL SYMPOSIUM ON DNA-ENCODED CHEMICAL LIBRARIES. Chengdu Marriot Financial Centre Chengdu, China October 17-19,
2 WARM WELCOME On behalf of the Organising Committees for 2018 International Symposium on the Frontiers and Practice of Innovative Drug Discovery and the 8th International Symposium on DNA-Encoded Chemical Libraries, we are delighted to invite you to join in this exciting events which will be held on Oct th, 2018 at the Marriot Hotel Financial Center in Chengdu, China. With a theme of INNOVATION, PRAGMATISM, COLLABORATION, industry experts and academic investigators in this increasingly important area will assemble to present and discuss the most recent developments and applications of this technology to early-stage small molecule drug discovery. Through a series of innovative R&D case studies, workshops, One-on-one Partnering Meeting, Road Show, Exhibition and Poster Presentation we will facilitate an international event with the capacity for thousands of attendees to participate in discussions and contribute to possible business collaborations across the industrial and academic spectrum. Symposium Introduction Date: Oct th, 2018 Location: Marriot Hotel Financial Center, Chengdu, China Language: English Symposium Topics 2018 International Symposium on the Frontiers and Practice of Innovative Drug Discovery Session 1: Analysis of Industrial Trends and Policies, Frontiers in Innovative Drug Discovery & Development Session 2: Case Studies of the Latest Innovative Drug Discovery & Development Session 3: New Approaches to Drug Discovery & Development: AI Application, Big Data, Block Chain, etc. 8th International Symposium on DNA-Encoded Chemical Libraries Session 1: Development of On-DNA Chemical Synthesis Session 2: New Technologies for DNA-encoded Library Selection and Hit Identification Session 3: Case Studies: Clinical Candidates from DNA-Encoded Libraries HOST SUPPORTERS CO-ORGANIZER ORGANIZER MEDIA
3 2018 INTERNATIONAL SYMPOSIUM ON THE FRONTIERS AND PRACTICE OF INNOVATIVE DRUG DISCOVERY COMMITTEE MEMBERS Dr. Bo Chen Founder & Chairman ConMed Biosciences Inc. Dr. Changyu Wang Founder & CEO Huamian Biotechnology Dr. Jin Li Founder, Chairman & CEO Dr. Min Wu Executive Director Asia Pacific Innovation AP Innovation Hub, BD&L. MSD R&D (China) Co., Ltd. Dr. Mingde Xia Senior Director Innovation center, Asia pacific, Johnson & Johnson Dr. Xianping Lu CEO & CSO Chipscreen Biosciences Dr. Yuan-Hua Ding Executive Director and Head of External Science & Innovation (ES&I), Asia-Pacific, Pfizer THE 8 TH INTERNATIONAL SYMPOSIUM ON DNA-ENCODED CHEMICAL LIBRARIES COMMITTEE MEMBERS Dr. Alex Shaginian Senior Director of Business Development and Chemical Sciences, Dr. Barry Morgan Chief Scientific Officer, Dr. Bing Xia Investigator, NCE ELTs Boston RD Platform Technology & Science, GSK Prof. Dario Neri Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology (ETH Zürich) & Cofounder, Philogen Dr. Jinqiao Wan Discovery Chemistry Unit, Dr. Robert Goodknow Innovation Chemistry, Pharmaron Dr. Sylvie K. Sakata Head of External Research Solutions, Global Research & Development, Pfizer Dr. Zhicai Shi Director of Chemistry Merck Sharp & Dohme
4 CONFIRMED SPEAKERS Dr. Alexander L. Satz Dr. Anthony D Keefe Dr. Barry Morgan Senior Principal Scientist Chief Scientific Officer Roche Dr. Bernd Nosse Discovery Technology, X-Chem Dr. Bing Xia b Prof. Dario Neri Global Head BD&L Technologies, Investigator, NCE ELTs Boston Department of Chemistry and Applied Boehringer Ingelheim Pharma RD Platform Technology & Biosciences, Swiss Federal Institute of GmbH & Co. KG Science, GSK Technology & Co-founder, Philogen Dr. David Isreal Dr. Dominik K. Kölmel Prof. Jianfeng Pei Senior Scientist, Worldwide Associate Professor Lead Discovery Sciences, Research and Development, Peking University Pfizer Dr. Jie Wang Post doctor, Department of Chemistry, TSRI Dr. John R Jacobsen Senior, Chemistry, DiCE Molecules SV, Inc Dr. Joseph Duffy Head of External Discovery Chemistry, Merck Research Lab, Merck & Co., Inc Dr. Kenneth E Lind Dr. Lee Babiss Dr. Lianshan Zhang Manager-Scientific President, SYNBLic Senior and Global Computing, R&D Platform R&D President of Jiangsu Hengrui Technology & Science, GSK Medicine Co.,Ltd. Dr. Lipeng Lai Ms. Lily Zhang Ms. Lynn Yang Co-founder and General Partner Managing Director Manager of Xtalpi Inc. CDH Investment Sequoia Capital Dr. Matthew Tremblay, Business Development, The Scripps Research Institute Prof. Mark P. Waller Shanghai University Dr. Min Wu Executive Director, Asia Pacific Innovation AP Innovation Hub, BD&L. MSD R&D (China) Co., Dr. Mingde Xia Senior Director Innovation center, Asia pacific, Johnson & Johnson Dr. Petr Vachal Associate of Discovery Chemistry, Merck & Co., Inc Dr. Xiaojie Lu Principal Investigator Shanghai Institute of Materia Medica Dr. Zhiqiang An UT s Institute of Molecular Medicine in Houston Dr. Nick Terrett Scientific Associate Vice President of European Chemistry Lead, MSD International GmbH Dr. Robert Goodknow Innovation Chemistry, Pharmaron Prof. Xiaoyu Li University of Hongkong Dr. Zhong-Yin Zhang Director of Purdue Institute for Drug Discovery Dr. Pei-Pei Kung Associate Research Fellow, Pfizer Dr. Wei Chen CEO, NetVation DL Medicine Dr. Yuan-Hua Ding Executive Director and Head of External Science & Innovation (ES&I), Asia-Pacific, Pfizer
5 AGENDA 2018 INTERNATIONAL SYMPOSIUM ON THE FRONTIERS AND PRACTICE OF INNOVATIVE DRUG DISCOVERY 15:00-21:00 On-site Registration 17:30-20:00 Dinner October 17, 2018 Opening Reception 08:00-09:00 On-site Registration 08:30-18:00 Poster Presentation October 18, talks + 1 panel discussion 08:30-18:00 Exhibition Open 13:00-18:00 One-on-One Partnering Meeting Session1: Analysis of Industrial Trends and Policies, Frontiers in Innovative Drug Discovery & Development 09:00-9:20 OPENING CEREMONY Welcome speech & Introduction of speakers 09:20-09:45 Government speech of Chengdu Tianfu International Bio-town Project Signing Ceremony: Scripps Project 09:45-10:15 TOPIC: TBD Dr. Dan Wang, Head of Johnson & Johnson Innovation Asia-Pacific 10:15-10:45 TOPIC: TBD Dr. Will Somers, and Head of BioMedicine Design, Pfizer 10:45-11:00 Conference Photo & Tea Break 11:00-11:30 Talk 11:30-12:00 Talk 12:00-13:00 Lunch & Exhibition & Poster Presentation 13:00-13:30 TOPIC: TBD 13:30-14:00 TOPIC: Synergies Between Innovation and Drug Development at Scripps Dr. Matthew Tremblay, of Business Development, The Scripps Research Institute & Chief Operating Officer of California Institute for Biomedical Research Session 2: Case Studies of the Latest Innovative Drug Discovery & Development 14:00-14:30 TOPIC: High-Throughput Experimentation for the Optimized Synthesis of TROX-1, a Cav2.2 Blocker for the Treatment of Chronic Pain Dr. Joseph Duffy, Head of External Discovery Chemistry, Merck Research Lab, Merck & Co., Inc 14:30-15:00 TOPIC: The Evolving Saga of Research & Development 15:00-15:30 Dr. Lee Babiss, President of SYNBLic TOPIC: TBD Dr. Lianshan Zhang, Senior and Global R&D President of Jiangsu Hengrui Medicine Co., Ltd. 15:30-15:45 Tea Break & Exhibition & Poster Presentation Panel Discussion: Cross-border Collaboration and Licensing in New Drug Discovery & Development
6 15:45-16:30 Chairperson : Panel Speakers: Dr. Yuan-Hua Ding, Executive Director and Head of External Science & Innovation (ES&I), Asia- Pacific, Pfizer Dr. Mingde Xia, Senior Director, Innovation center, Asia pacific, Johnson & Johnson Dr. Min Wu, Executive Director, Asia Pacific Innovation AP Innovation Hub, BD&L. MSD R&D (China) Co., Ltd. Dr. Bernd Nosse, Global Head BD&L Technologies, Boehringer Ingelheim Pharma GmbH & Co. KG 16:30-17:45 SAPA Roadshow 17:45-18:00 Poster Presentation 18:00-20:00 Dinner PLACE (TBD) 08:30-18:00 Poster Presentation 08:30-18:00 Exhibition 08:30-18:00 One-on-One Partnering Meeting October 19, talks + 1 panel discussion Session 2: Case Studies of the Latest Innovative Drug Discovery & Development (3 talks) 09:00-09:30 TOPIC: Antibody Drug Discovery: Challenges and Opportunities Prof. Zhiqiang An, UT s Institute of Molecular Medicine in Houston 09:30-10:00 TOPIC: Drugging the Undruggable: Targeting Protein Tyrosine Phosphatases for Novel 10:00-10:30 Talk Therapeutics Prof. Zhong-Yin Zhang, Director, Purdue Institute for Drug Discovery 10:30-10:45 Tea Break & Exhibition & Poster Presentation Session 3: New Approaches to Drug Discovery & Development: AI Application, Big Data, Block Chain, etc. 10:45-11:15 TOPIC: Drug Discovery Enabled 11:15-11:45 TOPIC: TBD Dr. Petr Vachal, Associate, Discovery Chemistry, Merck & Co., Inc. Dr. Lipeng Lai, Co-founder and General Manager of Xtalpi Inc. 11:45-12:15 TOPIC: Prediction of Druggable Proteins Using a Word2vec Algorithm Prof. Jianfeng Pei, Associate Professor, Peking University 12:15-13:15 Lunch & Exhibition & Poster Presentation 13:15-14:45 TOPIC: TBD 14:45-15:15 TOPIC: TBD 15:15-15:45 Talk 15:45-16:30 Chairperson: Prof. Mark P. Waller, Shanghai University Dr. Zhiyong Xie, Director of Digital Medicine, Pfizer Panel Discussion: Biomedical Investment Environment and Trends Panel Speakers: Ms. Lynn Yang, Managing Director, Sequoia Capital Ms. Lily Zhang, Partner, CDH Investment 16:30-17:45 Road Show 17:45-18:00 Closing Remarks 18:00-20:00 Closing Dinner PLACE (TBD)
7 THE 8 TH INTERNATIONAL SYMPOSIUM ON DNA-ENCODED CHEMICAL LIBRARIES October 19, 2018 TIME TOPIC & SPEAKER MODERATOR 08:30-09:00 On-site Registration 09:00-09:10 Introduction and Welcome Session 1: Development of On-DNA Chemical Synthesis 09:10-09:40 Talk 09:40-10:10 10:10-10:40 10:40-11:00 Tea Break TOPIC: Employing Photoredox Catalysis for the Synthesis of DNA-encoded Libraries Dominik K. Köelmel, PhD, Senior Scientist, Worldwide Research and Development, Pfizer TOPIC: Forging Csp3-Csp3 and Csp3-Csp2 Bonds in DEL-Format Jie Wang, PhD, Post doctor, Department of Chemistry, The Scripps Research Institute TOPIC: Encoded Self-Assembling Chemical (ESAC) Libraries 11:00-11:30 Dario Neri, Professor, Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology 11:30-12:00 Talk 12:00-13:00 Lunch Session 2: New Technologies for DNA-encoded Library Selection and Hit Identification 13:00-13:30 TOPIC: TBD David Israel, PhD, of Lead Discovery Sciences, HitGen 13:30-14:00 TOPIC: The Encoded Library Technology Data Analysis Platform at GSK Kenneth E Lind, PhD, Manager Scientific Computing, R&D Platform Technology & Science, GSK 14:00-14:30 TOPIC: DNA-Programmed Chemistry: Application to Lead Expansion of a Peptide Macrocycle John R Jacobsen, PhD, Senior, Chemistry, DiCE Molecules SV, Inc 14:30-15:00 Talk 15:00-15:20 Tea Break Session 3: Case Studies: Clinical Candidates from DNA-Encoded Libraries 15:20-15:50 TOPIC: Use of DNA encoded libraries at Roche Alexander L. Satz, PhD, Senior Principal Scientist, Roche 15:50-16:20 TOPIC: Characterization of specific Naa50 inhibitors identified using a DNA encoded library: a lead-finding case study for a challenging target Pei-Pei Kung, PhD, Associate research fellow of Pfizer 16:20-16:50 TOPIC: Therapeutic Discovery and Technology Development with the X-Chem DNA-Encoded Chemistry Platform Anthony Keefe, PhD, of Discovery Technology, X-Chem Pharmaceuticals 16:50-17:20 Panel Discussion - Speakers: Barry Morgan, PhD, Chief Scientific Officer, HitGen Xiaojie Lu, Professor, Principal Investigator, Shanghai Institute of Materia Medica Xiaoyu Li, Professor, University of Hongkong 17:20-17:30 Closing Remarks 18:00-20:00 Closing Dinner PLACE (TBD) Jin Li, PhD, Founder and Chairman & CEO of HitGen MODERATOR Barry Morgan, PhD, Chief Scientific Officer of HitGen MODERATOR Dario Neri, Professor, ETH Zürich MODERATOR Nick Terrett, PhD, VP of European Chemistry Lead, MSD International GmbH Robert Goodknow, PhD, VP, Innovation Chemistry, Pharmaron
8 REGISTRATION It is free event but we do provide paid catering service. Visit our websites to help you confirm your online registration no later than Oct 15, th-symposium-on-dna-encoded-chemical-library.eventbrite.hk VENUE & TRANSPORTATION Chengdu Marriott Hotel Financial Centre Add: No 999 TianFu Avenue North, High-Tech Zone, Wuhou, Chengdu, China Tel: Chengdu Shuangliu International Airport: 9.3 miles Subway: Get off atjinrongcheng Station, 800 m from the symposium spot Bus: 74, 118, 220, 501, 504, 506, 898, G32 are all available to arrive atsymposium
9 CONTACT US FOR REGISTRATION & MEDIA Contact Haiying Xue at OR CALL (86) FOR PRESENTATION We will have 30 talks for both symposiums. If you would like to apply to be a speaker, please kindly send your materials (applicant s name, title, contact information, biography, company name, company introduction, topic, abstract and high-resolution picture) to zq.he@hitgen.com no later than August 15, 2018 OR CALL (86) for more information. FOR One-on-One MEETING &ROAD SHOW If you would like to apply for a road show, please kindly send your materials (applicant s name, title, contact information, biography, company name, company introduction, project introduction ) to sj.lei@hitgen.com no later than August 15, 2018 OR CALL (86) for more information. FOR POSTER & SPONSORSHIP Contact Ning Ding at @qq.com OR CALL (86) FOR INVITATION LETTER FOR VISA APPLICATION If you would like to have invitation letter for visa application, please kindly contact Shelly He at zq.he@hitgen.com OR CALL (86) for more information.
2018 INTERNATIONAL SYMPOSIUM ON THE FRONTIERS AND PRACTICE OF INNOVATIVE DRUG DISCOVERY
2018 INTERNATIONAL SYMPOSIUM ON THE FRONTIERS AND PRACTICE OF INNOVATIVE DRUG DISCOVERY THE 8 TH INTERNATIONAL SYMPOSIUM ON DNA-ENCODED CHEMICAL LIBRARIES. Chengdu Marriot Financial Centre Chengdu, China
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