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1 National Science Foundation at Mississippi State University Dr. Joann Roskoski Executive Officer Directorate for Biological Sciences October 10, 2008

2 NSF in a Nutshell Independent Agency Primarily y Uses Grant Mechanism Low Administrative Costs Discipline-based structure

3 NSF Vision Advancing discovery, innovation, and education beyond the frontiers of current knowledge, and empowering future generations e in science ce and engineering. NSF-3

4 NSF s Strategic Goals Discovery Foster research that will advance the frontiers of knowledge, emphasizing i areas of greatest t opportunity and potential benefit and establishing the Nation as a global leader in fundamental and transformational science and engineering Learning Cultivate a world-class, broadly inclusive science and engineering workforce, and expand the scientific literacy of all citizens Research Infrastructure Build the Nation s research capability through critical investments in advanced instrumentation, facilities, cyber infrastructure, and experimental tools Stewardship Support excellence in science and engineering research and education through a capable and responsive organization

5 The Political Climate

6 America COMPETES Act Authorizes budget levels at the National Institute of Standards and Technology, the Department of Energy's Office of Science, and the National Science Foundation (NSF) on a path to doubling within the near term. The total NSF budget is authorized to double its budget in approximately seven years.

7 APPROPRIATIONS FOR NSF FY Request % Annually 0.19% Annually Dollars 5 4 ons of Billi

8 $6.854 billion Increase over FY 2008 Request: $822.,1 million, 13.6%

9 NSF Budget by Directorate NSF by Account FY 2007 Actual FY 2009 Budget Request to Congress FY 2008 Estimate (Dollars in Millions) FY 2009 Request FY 2009 Request change over: FY 2007 Actual FY 2008 Estimate Amount Percent Amount Percent BIO $ $ $ $ % $ % CISE % % ENG (less SBIR/STTR) % % SBIR/STTR % % GEO % % MPS 1, , , % % SBE % % OCI % % OISE % % OPP % % IA % % U.S. Arctic Research Commission % % Research & Related Activities $4, $4, $5, $ % $ %

10 Proposal, Award and Funding Trends

11 NSF PROPOSAL STATISTICS (FY 2008) 44,199 proposal actions ~248,000 reviews ~45,000 reviewers 11,156 awards 25.0% funding rate (Research 21%)

12 NSF RESEARCH GRANT PROFILE (FY 2008) Competitive awards (Research): 7,022 Average annual award: $143,212 Median annual award: $110,000 Average duration (research): 3.00 years

13 Type of Review Year Mail & Mail Panel Panel Only Only % 30% 41% % 8% 56%

NSF Organizational Chart Office of Cyberinfrastructure Office of Equal Employment

the General Counsel Office of Integrative Activities Office of the Inspector General

Affairs Office of Polar Programs Biological Sciences (BIO) Computer & Information

Physical Sciences (MPS) Social, Behavioral & Economic Sciences (SBE) Education &

14 NSF Organizational Chart Office of Cyberinfrastructure Office of Equal Employment Opportunity Programs National Science Board (NSB) Director Deputy Director Office of the General Counsel Office of Integrative Activities Office of the Inspector General (OIG) Office of International Science & Engineering Office of Legislative & Public Affairs Office of Polar Programs Biological Sciences (BIO) Computer & Information Science & Engineering (CISE) Engineering (ENG) Geosciences (GEO) Mathematical & Physical Sciences (MPS) Social, Behavioral & Economic Sciences (SBE) Education & Human Resources (EHR) Budget, Finance & Award Management (BFA) Information & Resource Management (IRM)

15 Biological Sciences (BIO) Vision Inspiring research and education at the frontiers of the life sciences Mission To enable the discoveries for understanding life

16 BIO Support for Basic Research Federal Support for Basic Research in Non-Medical Biological Sciences at Academic Institutions Federal Support for Basic Research in Environmental Biology at Academic Institutions NSF 67% NSF 62% Other federal Other federal spending 33% spending 38%

17 Directorate for Biological Sciences (BIO) Division of Biological Infrastructure (DBI) Division i i of Division i i of Division i i of Integrative Organismal Systems (IOS) Environmental Biology (DEB) Molecular and Cellular Biosciences (MCB) Human Resources Ecological Biology Behavioral Systems Biomolecular Systems Research Resources Ecosystem Science Developmental Systems Cellular Systems Plant Genome Research Program Population and Evolutionary Processes Neural Systems Genes and Genome Systems Systematic Biology and Biodiversity Inventories Physiological and Structural Systems Emerging Frontiers (EF) Effective April, 2008

18 BIO Priorities Life in Transition Strengthening Core Programs Origins Energy Adaptation ti NEON The Life Sciences in Transition Multidisciplinary Programs Multidisciplinary Centers Plant Science Cyberinfrastructure Collaborative Centers for Environmental Implications of Nanotechnology National Institute for Mathematical and Biological Synthesis

19 Origins: How, where and when did life on Earth begin? Open system chemistry Self-replication li RNA World DNA World Basic elements H 2 + CO 2 => [ HCO ] n Self-sustaining biochemistry How did the biological complexity of life emerge from pre-biotic chemistry and geochemistry? Self-contained The Cell Self-sustaining - Energy Self-replicating RNA, DNA Evolving - Biodiversity

20 How is energy obtained and used by living systems to sustain life? Applied Photosynthesis Au PS I Ag e - e - e - Assemble the basics Chloroplasts Barry Bruce (UTN), NSF/EF -/+ e - Understanding natural energy transduction systems will inspire the development of biologybased technologies capable of delivering sustainable, renewable, efficient energy.

21 Adaptation Transformations and Transitions in the Story of Life Diversity Changes What will survive, and how? Understanding life s resilience and adaptation will reduce uncertainty about the future of life on Earth in response to global l climate change: Adaptive Systems Technology Dynamics of Water Processes in the Environment NEON

22 Adaptation: Life in a Time of Planetary Change CH CO 4 2 We are only now beginning to explore the biological drivers of climate change.

23 NEON Biosphere, Geosphere, Atmosphere

24 Multidisciplinary Programs Dynamics of Coupled Natural and Human Systems (BIO, GEO, SBE and USFS) Interdisciplinary Training for Undergraduates in Biological and Mathematical Sciences (BIO,EHR,MPS) Ecology of Infectious Disease (BIO, GEO, SBE and NIH)

25 Computer and Information Science and Engineering (CISE) Office of the Assistant Director for CISE CCF Computing and Communications Foundations CNS Computer and Network Systems IIS Information and Intelligent Systems RAMS PROG CORE Algorithmic Foundations Computer Systems Human-Centered Research Computing Communications and Information Foundations Software and Hardware Foundations Networking Technology and Systems Information Integration and Informatics Robust Intelligence

26 Computer Information Science and Engineering (CISE) Discovery: Advance the Frontiers of Computing Core CISE programs Cross-cutting research program New solicitation that covers areas that cut across the CISE divisions and that could benefit from intellectual contributions of researchers with expertise in a number of fields or sub-fields Invites small (<$500K), medium (<$1.2M) and large (<$3M) projects Focus Areas Data-Intensive Computing Network Research and Engineering Trustworthy Computing

27 CS CISE Discovery: Advance the Frontiers of Computing Multidisciplinary program solicitations Cyber-Enabled Discovery and Innovation (CDI) began in FY 08 Collaborative Research for Computational Neuroscience (CRCNS) Advanced Learning Technologies (ALT) Center-like programs (funding of several $M/year/project for 5-10 years) Science and Technology Centers Engineering i Research Centers Expeditions in Computing

Cyber-Enabled Discovery and Innovation (CDI) Create revolutionary science and engineering i research outcomes made possible by innovations and advances in computational thinking.

28 Cyber-Enabled Discovery and Innovation (CDI) Create revolutionary science and engineering i research outcomes made possible by innovations and advances in computational thinking. Seek ambitious, transformative, multidisciplinary research proposals within or across the following thematic areas: From Data to Knowledge Understanding di Complexity in Natural, Built, and Social Systems Building Virtual Organizations Bold Five-Year Initiative See

Expeditions Pursue ambitious, fundamental research that promises to define the future of

far-reaching research explorations motivated by deep scientific questions Inspire current and

significant research and education outcomes that promise scientific, economic and/or other

29 Expeditions Pursue ambitious, fundamental research that promises to define the future of computing Investigators collaborate across disciplinary and institutional boundaries Catalyze far-reaching research explorations motivated by deep scientific questions Inspire current and future generations of Americans, especially those from under-represented groups Stimulate significant research and education outcomes that promise scientific, economic and/or other societal benefits Preliminary Proposal Due Date (required): September 10, 2008 Full Proposal Deadline: January 10, 2009

30 CISE Learning: Build a highly competent and diversified computing workforce for the 21 st century CISE-specific CISE PATHways (CPATH) to Revitalized Education in Computing Broadening Participation in Computing (BPC) NSF-wide programs

31 Education and Human Resources Mission & Goals Mission: To enable excellence in U.S. STEM education at all levels and in all settings in order to support the development of a diverse and well-prepared workforce of scientists, technicians, engineers, mathematicians, and educators. Goals: To prepare the next generation of STEM professionals; To promote rigorous research and evaluation on STEM education and the workforce; To heighten the scientific literacy of the population; & To broaden participation i i in STEM.

32 Thematic Framework for Directorate-wide Coordination and Connections

33 EHR s Organizational Structure Office of the Assistant Director Division of Graduate Education (DGE) Division of Human Resource Development (HRD) Division of Research on Learning in Formal and Informal Settings (DRL) Division of Undergraduate Education (DUE)

Core DUE Programs Advanced Technological Education (ATE) Course, Curriculum and Laboratory Improvement (CCLI) Federal Cyber Service: Scholarship for Service Math and Science Partnership (MSP)

34 Core DUE Programs Advanced Technological Education (ATE) Course, Curriculum and Laboratory Improvement (CCLI) Federal Cyber Service: Scholarship for Service Math and Science Partnership (MSP) Excellence Awards in Science and Engineering (EASE) National Science, Technology, Engineering, and Mathematics Education Digital Library (NSDL) NSF Scholarships in Science, Technology, Engineering, and Mathematics (S-STEM) Robert Noyce Teacher Scholarship Program (NOYCE) Science, Technology, Engineering, and Mathematics Talent Expansion Program (STEP) Interdisciplinary Training for Undergraduates in Biological and Mathematical Sciences (UBM)

35 Core DGE Programs Graduate Research Fellowship Program (GRF) Integrative Graduate Education and Research Traineeship Program (IGERT) NSF Graduate Teaching

36 DRL Core Programs Discovery Research K-12 (DR-K12) Informal Science Education (ISE) Innovative Technology Experiences for Students t and Teachers (ITEST)

HRD Core Programs Research in Disability Education (RDE) Tribal Colleges and

Advancement of Women in Academic Science and Engineering Careers Research on

Science and Technology (CREST) Alliances for Broadening Participation in

37 HRD Core Programs Research in Disability Education (RDE) Tribal Colleges and Universities Program (TCUP) ADVANCE: Increasing the Participation and Advancement of Women in Academic Science and Engineering Careers Research on Gender in Science and Engineering (GSE) Centers for Research Excellence in Science and Technology (CREST) Alliances for Broadening Participation in STEM (ABP) Historically Black Colleges and Universities Undergraduate Program (HBCU-UP)

38 Engineering (ENG) Emerging Frontiers in Research and Innovation (EFRI) Sohi Rastegar Office of the Assistant Director TBD Deputy Assistant Director Michael Reischman Program Director for Diversity & Outreach Mary Juhas Senior Advisor for Nanotechnology Mihail Roco Engineering Education and Centers (EEC) Allen Soyster Chemical, Bioengineering, Environmental, and Transport Systems (CBET) John McGrath Civil, Mechanical, and Manufacturing Innovation (CMMI) Adnan Akay Electrical, Communications, and Cyber Systems (ECCS) Lawrence Goldberg Industrial Innovation and Partnerships (IIP) Kesh Narayanan

39 Engineering (ENG) Research and Education Themes Cognitive engineering: Intersection of engineering and cognitive sciences Competitive manufacturing and service enterprises Complexity in engineered and natural systems Energy, water, and the environment Systems nanotechnology

advanced materials Advancing quantum information processing Combining maps (gray square) and density of cell-phone usage

40 Complexity in Engineered and Natural Systems Addresses unifying principles that enable modeling, prediction, and control of emergent behavior in complex systems Examples include: Improving structural performance during disasters through advanced materials Advancing quantum information processing Combining maps (gray square) and density of cell-phone usage (shown as red and yellow 3-D peaks) can yield information about how a complex system responds to unplanned events. Dahleh,

41 Competitive Manufacturing and Service Enterprises Enables research to catalyze multiscale manufacturing, from fundamental metrology through atomic-scale control of raw materials Examples include: Developing quality-engineered nanomaterials in necessary quantities Achieving perfect atomic- and molecular-scale manufacturing Nanoparticles compose a lightweight biocompatible material for bone implants. Groza,

Energy, Water, and the Environment Supports breakthroughs essential to the provision of energy and

Examples include: Increasing the use of alternative energy sources through research in materials

water purification and desalinization begins with understanding of how ions in water interact with

42 Energy, Water, and the Environment Supports breakthroughs essential to the provision of energy and water in an environmentally sustainable and secure manner. Examples include: Increasing the use of alternative energy sources through research in materials Developing quantitative understanding of energy environment interactions (including water) Advanced water purification and desalinization begins with understanding of how ions in water interact with purification membranes. This dynamic computer simulation shows sodium (pink) and chlorine (green) ions inside a polyamide membrane. Shannon,

43 Systems Nanotechnology Supports fundamental research that leads to the development of active and complex nanosystems and their integration with biology, energy, and other fields Examples include: Developing high-specificity sensors for national security Developing tools to move into the 3 rd dimension and into time resolutions of chemical reactions Integrated circuits that are smaller and faster are possible with microfluidics systems built from or incorporating nanocomponents. Ferreira,

GEOSCIENCES (GEO) Atmospheric Sciences Meteorology Climate Dynamics and Paleoclimate Atmospheric Chemistry Aeronomy Magnetospheric Physics Earth Sciences Paleobiology, Sedimentary Geology Geophysics

44 GEOSCIENCES (GEO) Atmospheric Sciences Meteorology Climate Dynamics and Paleoclimate Atmospheric Chemistry Aeronomy Magnetospheric Physics Earth Sciences Paleobiology, Sedimentary Geology Geophysics & Geochemistry Tectonics & Continental Dynamics Hydrologic Sciences & Geomorphology Geobiology EarthScope Program Major Facilities (COMPRESS, IRIS, etc.) Ocean Sciences Physical Oceanography Biological Oceanography Chemical Oceanography Marine Geology and Geophysics Solar-Terrestrial Physics g Major Facilities (NCAR, Incoherent Scatter Radars, etc.) Oceanographic Technology Ocean Drilling Program Major Facilities (Ships, ALVIN, etc.)

45 Atmospheric Sciences (ATM) furthers understanding di of weather, climate and the solar-terrestrial system by expanding the fundamental knowledge of the composition and dynamics of the Earth s atmosphere and geospace environment supports large, complex facilities required for research in the atmospheric and solar-terrestrial sciences

46 Earth Sciences (EAR) improves the understanding of the structure, composition, and evolution of the Earth and the processes that t govern the formation and behavior of the solid Earth supports theoretical, computational, laboratories and field stations and state-of- the-art scientific infrastructure

47 Ocean Sciences (OCE) enhances understanding of all aspects of the global oceans and their interactions with the solid earth and the atmosphere, including supports major shared-use oceanographic facilities including research vessels and manned deep diving submersibles

48 Cross-Cutting Activities in GEO Emerging Topics in Biogeochemical Cycles Paleo Perspectives on Climate Change Geoscience Education & Diversity

Critical Zone Observatories (CZO) Critical Zone Observatories

our understanding of the integration and coupling of Earth

methods, as well as theoretical techniques, each providing

49 Critical Zone Observatories (CZO) Critical Zone Observatories operate at the watershed scale and will significantly advance our understanding of the integration and coupling of Earth surface processes as mediated by the presence and flux of fresh water. Observatories include field and analytical l research methods, as well as theoretical techniques, each providing the impetus for advances in the other, as well as substantial and novel plans for education, outreach and broader impacts.

50 International Collaboration at NSF NSF support for international collaboration aims to: Advance the FRONTIERS of Science and Engineering ACCESS to unique expertise, facilities, and phenomena LEVERAGE limited resources Prepare a GLOBALLY-ENGAGED U.S. S&E workforce DEVELOP understanding of science abroad NURTURE capable, confident, adaptable young researchers with strong networks overseas

51 International Collaboration at NSF NSF supports the U.S. side of an international ti collaboration In principle, overseas researchers brings their own resources to the collaboration Some exceptions for developing countries Consult OISE program officer about specifics

International Collaboration at NSF Support

research or education programs New proposal

52 International Collaboration at NSF Support for International Activities is integrated throughout NSF Supplements to existing NSF grants Integral part of new proposals to NSF research or education programs New proposal to the Office of International Science and Engineering

53 MPS Directorate Directorate for Mathematical and Physical Sciences Astronomy Chemistry Materials Research Mathematical Sciences Physics Office of Multidisciplinary Activities 11/48

54 Astronomical Si Sciences (AST) Astronomy and Astrophysics Grants Extragalactic Astronomy and Cosmology Galactic Astronomy Planetary Astronomy Stellar Astronomy and Astrophysics Education and Special Programs Electromagnetic Spectrum Management Advanced Technologies and Instrumentation Major Research Instrumentation University Radio Observatories Program for Research and Education with Small Telescopes Astronomy and Astrophysics Postdoctoral Fellowships 19/48

55 Materials Research (DMR) Advanced Materials and Processing Cluster Metals, Ceramics and Electronic Materials Base Science Cluster Condensed Matter Physics Solid-Sate Chemistry and Polymers Materials Research and Technology Enabling Cluster Materials Research Science and Engineering Centers Materials Theory National Facilities and Instrumentation Office of Special Programs 25/48

56 Analysis Mathematical Sciences Applied Mathematics Algebra, Number Theory, Combinatorics, and Foundations Computational Mathematics Geometric Analysis and Topology Statistics and Probability Infrastructure 30/48

Facilities: Physics (PHY) LHC, LIGO, IceCube, NSCL, CESR Centers/ Institutes Programs: 4% Atomic, Molecular, Optical, and Plasma Physics Biological Physics Elementary Particle Physics Gravitational

57 Facilities: Physics (PHY) LHC, LIGO, IceCube, NSCL, CESR Centers/ Institutes Programs: 4% Atomic, Molecular, Optical, and Plasma Physics Biological Physics Elementary Particle Physics Gravitational Physics Nuclear Physics Particle and Nuclear Astrophysics Physics at the Information Frontier Physics Frontiers Centers Theoretical Physics Education and Interdisciplinary Programs Education/ Workforce 3% Facilities/ Instrumentation 35% Advancing the Frontier 58% 33/48

58 Division of Chemistry (CHE) Organic and Macromolecular Chemistry Inorganic, Organic Dynamics Organic Synthesis Bioinorganic & Organometallic Chemistry Physical Chemistry Theoretical and Computational Chem. Experimental Analytical Physical & Chemistry Chemistry Surface Chemistry Inorganic, Bioinorganic, and Organometallic Centers Chemistry Analytical and Surface Chemistry Facilities and Integrated Chemical Activities Chemical Instrumentation Programs Research Experience for Undergraduates Undergraduate Research Centers Discovery Corp Fellows 82 Education Other Collaboratives Instrumentation Centers Frontier Programs 21/48

59 Scientific Opportunities Physical sciences at the nanoscale Science ce beyond Moore s e s Law Physics of the universe Complex systems (multi-scale, emergent phenomena) Fundamental mathematical and statistical science Sustainability (energy, environment, climate) Computational and Cyber-enabled Discovery and Innovation Interface between the physical and life sciences 13/48

60 Office of the Director Directorate for Social, Behavioral & Economic Sciences Social and Economic Si Sciences Behavioral and Cognitive Si Sciences Science Resources Statistics

61 Social, Behavioral & Economic Sciences Programs Disciplinary Cultural Anthropology Physical Anthropology Archaeology Linguistics Social Psychology Economics Sociology Political Science Inter-Disciplinary Cognitive Neuroscience Developmental & Learning Sciences Documenting Endangered Languages Perception, Action & Cognition HOMINID Geography & Regional Science Decision, Risk & Management Sciences Science of Science & Innovation Policy Innovation & Organizational Sciences Methodology, Measurement & Statistics Science, Technology, & Society Law & Social Sciences

62 Social and Behavioral Sciences New Technologies (SBE) : Themes Intertwinements with Natural and Life Sciences Centrality of Mind/Brain Adaptive Systems Technology Complexity Cyber-Enabled Discovery & Innovation Emergent phenomena Tipping points Links to policy

63 Social, Behavioral & Economic Sciences Joint Funding Joint-Funded Programs Funding Partners Cognitive Neuroscience Ecology of Infectious Disease Biology & Society Dynamics of Coupled Natural & Human Systems (CNH) Sensors Nanotech & Society Cyber-enabled enabled Discovery & Innovation (CDI) Cyberinfrastructure NIH CISE BIO GEO ENG MPS NSF-Wide Initiatives

64 Programs for Specific Groups -Purposes Grant Opportunities for Acad Liaison with Industry (GOALI) Major Research Instrumentation (MRI) Integrative Graduate Ed and Res Traineeship (IGERT) Faculty Early Career Development (CAREER) Program Research Experiences for Undergraduates (REU) Research in Undergraduate Institutions (RUI) NSF Graduate Teaching Fellows in K-12 Education ADVANCE: Increasing the Participation and Advancement of Women in Academic Science and Engineering ing Careers Cyber-enabled Discovery and Innovation

65 New Program Solicitations CHE-DMR-DMS Solar Energy Initiative (SOLAR) Program Solicitation - NSF International Collaboration in Chemistry between US Investigators and their Counterparts Abroad (ICC) Program Solicitation NSF Mathematical Sciences Research Institutes Program Solicitation NSF Proactive Recruitment in Introductory Science and Mathematics (PRISM) Program Solicitation NSF Multicore Chip Design and Architecture: (MCDA) AJ Joint Initiative i i between the National Science Foundation and the Semiconductor Research Corporation Program Solicitation NSF

66 National Science Foundation Update *And How To Find It

70 Summary Points For new opportunities look for current information on the web ( Proposal and Award Policies and Procedures Guide sp?ods_key=papp p pp NSF Program Directors can help you find the most appropriate program(s) When in doubt

NSF Investments in Synthetic Biology

NSF Investments in Synthetic Biology National Science Foundation Directorate for Biological Sciences Molecular and Cellular Biosciences Directorate for Engineering Emerging Frontiers in Research and Innovation Chemical Bioengineering Environmental