Bringing world class innovations to market by bridging discoveries into commercial products. February 27, 2015 The Entrepreneurs EDGE
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1 Bringing world class innovations to market by bridging discoveries into commercial products. February 27, 2015 The Entrepreneurs EDGE
2 Cleveland Clinic 5.5M Patient Visits 43,430 Employee Caregivers 27 Institutes providing care in 120 subspecialties Locations Main Campus 8 Community Hospitals 16 Family Health Centers in NE Ohio Facilities in Florida, Nevada, Toronto & Abu Dhabi EMR Leader My Chart Top 4 Hospital by U.S. News & World Report
3 Main Campus
4 Cleveland Clinic Lou Ruvo Center for Brain Health
5 Cleveland Clinic Abu Dhabi 5
6 R.E. Jacobs Health Center 6.4M Patients Elyria Family Health Center Lorain Family Health And Surgery Center Lou Ruvo Center for Brain Health Las Vegas, Nevada Westlake Family Health Center H Fairview Hospital H Lakewood Hospital Strongsville Family Health and Surgery Center Lakewood Family Health Center H Lutheran Hospital Independence Family Health Center Brunswick Family Health Center H Euclid Hospital Cleveland Clinic H Marymount Hospital Wooster Family Health Center H South Pointe Hospital H Medina Hospital HC Cleveland Clinic Toronto S.T.J. Health Center Solon Family Health Center Chagrin Falls Family Health Center H Ashtabula County Medical Center Willoughby Hills Family Health Center H Hillcrest Hospital Beachwood Family Health and Surgery Center Twinsburg Family Health Center H Cleveland Clinic Florida
7 Cleveland Clinic Culture Quality. INNOVATION. Teamwork. Service. Integrity. Compassion. We welcome change, encourage invention and continually seek better, more efficient ways to achieve our goals. "We are considering not only our duty to the patient of today, but no less our duty to the patient of tomorrow." George Crile, Sr., MD Co-Founder Cleveland Clinic
8 Cleveland Clinic Innovations We promote innovation and expand treatment of the sick through the deployment of technologies developed by Cleveland Clinic and our Healthcare Innovations Alliance Partners. Through commercialization, we translate emerging diagnostics, therapies, devices, health IT and business solutions into beneficial medical products through spin-off companies, licenses and equity partnerships.
9 Promote Innovation via Commercialization Bring new innovations into widespread clinical practice Protect the intellectual property underlying the innovations Optimize the value returned for those innovations Grow the regional economy and beyond
10 Areas of Focus 1. Commercialization / technology transfer 2. Global Healthcare Innovation Alliance 3. Medical Innovation Summit 4. Centers (GCIC & NCAI)
11 Business Imperatives Commercializing/translating innovations that provide better patient care; Delivering exceptional inventor satisfaction through teamwork; Optimizing financial outcomes.
12 Innovations Scorecard: ,600 Patent Applications 450 Royalty Licenses 71 Spin-Offs $799M in Equity Investments $69M to Inventors $167M in State & Federal Grants 1,200 Jobs Created World-Wide Recognition
13 Innovations Key Metrics Agreements Companies IDFs Patents Agreements Companies Formed Patents Filed Patents Issued IDFs 0 *IDFs include Alliance Partners
14 Inventions by Type 2014 Therapeutics & Diagnostics 22% Delivery Solutions 5% Medical Device 50% Health IT 23%
15 Portfolio Companies: ART SARL CleveX Clear Catheter Solutions ATI Congruent Medical AxioMed IntElect Tolera CardioNomic OptoQuest Image IQ Custom Arthroplasty Solutions NaviGate icomet ivhr Renovo Biosciences FlexLife Health Shield Biotech Adeo Centerline Medical CardioMEMS Merlot Revasc Cleveland Heart Perfusion Solutions SironRX Custom Ortho Solutions Infuseon Jace Medical VBT Cleveland BioLabs CSF Therapeutics Alios Biopharma Navis Renovo Neural YouDocs Beauty Enspire DBS Ion-VAC Cancer Genetics Emanate Wireless Peritec PrognostiX Juventas Clear Catheter Systems Buckeye Ocular ValveXchange OrthoMems AngioQuest Cleveland HeartLab Enforcer PluronX i360medical Cleveland Diagnostics Sivan Panacela* RelateCare BioSil, USA VioQuest Explorys Incuron* Rindex Talis Z-Kat Zin Medical Ridgeway Simbionix Clear Ventric Intellis I-Lyte IPPC Esperion Monetized *CBLI Spin-off Dissolved Therapeutics HIT Services Diagnostics Device Non-operating
16 A Comprehensive Approach Mine for IDEAS with clinically aligned Institute Innovation Managers Engage clinical and technical inventor peers to evaluate NEED Assess the commercial VIABILITY and build a business case Develop within a domain specific incubator for ENHANCEMENT, then market Manage NEGOTIATIONS to create spin-offs, licenses and equity partnerships Take idea through TRANSLATION to improve patient care
17 Process Flow Cleveland Clinic Innovations Incubators Peer Review (PRC) CCI Facilitated, Enterprise Aligned, Institute Driven Medical Device Therapeutic Health IT Delivery Solutions Industry & Investor Advisory
18 Value Proposition & Outcomes Inventor Satisfaction Greater Awareness of Innovation Expanded Involvement Improved Commercial Outcomes Increased Transparency for Stakeholders Access to Clinical, Technical, & Industry Experts Enhanced Quality Increase Value
19 A World Class Model * * *international
20 2015 Medical Innovation Summit
21 Sponsor Innovation Access The Summit welcomes over 1,700 healthcare decision makers to discuss the latest breakthrough medical technologies Lead Your support demonstrates a commitment to leading the conversation in medical innovation Partner Sponsors are encouraged to network with Cleveland Clinic caregivers to initiate collaborative ideas For more information, contact Susan Bernat ( bernats@ccf.org)
22 The future belongs to those who seize the opportunities created by innovation." Delos M. Cosgrove, MD CEO & President Cleveland Clinic
23 Stay Connected! innovations.clevelandclinic.org
24
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