TouchBright Ver. 7.51

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TouchBright Ver. 7.51 High-Performance LED Excitation System Efficient Use Long Lifetime Brightest LEDs Compact Design High-Performance Live Cell Instrument Co., LTD www.touchbrightled.com

TouchBright X5 High-Performance 5 LED-Excitation System TouchBright X5 Illumination System can be directly attached to the microscope without light guide which is caused decrease of the light. Enable to provide highest intensity of the light from LEDs. Through unique composition of optical filters, enable to rapidly change the colors of LEDs and turn on/off LEDs. 4 heat sinks eliminate the heat of the LEDs consistently. External white LED can be substituted for the halogen lamp which is used for transmitted image. UV, blue, green and red LEDs as standard, but changeable to other colors depending on user s request. Active air cooling system to sink the heat and to monitor the temperature constantly, enable to maintain constant highest intensity of the light from LEDs. Unique composition of optical filters allows the light of LEDs rapidly changeable. 4 heat sinks eliminate the heat of the LEDs consistently. Can be directly attached to a microscope TouchBright X5, X6 illumination system can be used with all microscopes with a common software package. (e.g. TTL, Nikon-NIS, Metamorph and Micromanager or etc.) Brightest LEDs & power stability Long lifetime Wide range of LED wavelengths External LED to substitute for the transmitted halogen lamp No warm up and cool down 0-100% intensity control No ND filter Touchscreen remote control pad Active cooling system (Patent pending) 1

TouchBright X6 High-Performance 6 LED-Excitation System TouchBright X6 is designed to rotate five colors of the ultra-high power LED modules with a single fiber optic guide. No requirement to use optical filters for gathering different colors of lights which is caused decrease of light. Enable to provide highest intensity of the light from LEDs. UV, blue, green, red and amber as standard but changeable to other colors depending on user s request. Automatic turn on/off of 300W radiator and active water cooling system when the heat is beyond the limit. Using the multiple lights at the same time for a special purpose, TouchBright TMC can be combined with X6, which contains a combiner, collimators, and dichroic mirrors.(refer to page 6) Five color-ultra high power LEDs 300 W radiator eliminates the heat of the LEDs Consistently. Active circulating plate for the effective cooling system LEDs position controller with the precision motor Common Fluorescence LED wavelength Fluorescence 365 nm DAPI, Fura-2, Alexa 350, Hoechst, Calcein blue, Indo-1, Qdot, AMCA 380 nm DAPI, Fura-2, Hoescht, Qdot, BFP, Indo-1 470 nm FITC, GFP, CFP, Alexa 488, CY2, Fluo3, Oregon Green 530 nm Alexa 514, Alexa 532, Alexa 546, YFP, Rhodamine phalloidin, RFP, mcherry 560nm (white) Texas Red, CY 3, CY 3.5, mcherry, Alexa 594 630 nm Alexa 633, Alexa, 647, Alexa 660, CY 5, APC, TOPRO-3, TOTO-3 LED wavelength displayed on the above table as standard. Changeable to other colors by referencing the ordering information. www.touchbrightled.com

TouchBright X5 & X6 High-Performance LED-Excitation System 120 Brightness variation of the LED temperature 2.5 Wavelength shift of the LED temperature 110 2.0 100 1.5 Brightness 90 80 70 Wave length 1.0 0.5 0 60-0.5 50-1.0 Heat sink temp. of the LED Heat sink temp. of the LED 40-1.5 20 30 40 50 60 70 80 90 20 30 40 50 60 70 80 90 Through the active cooling system, the LED can provide the brightest and maximized illumination consistently while it minimizes the wavelength shift. Consistent and stable transmitted light intensity reduces and minimizes the error of the fluorescence images during bio-imaging experiments. TouchBright Brightness Reduction of the LED Brightness maintenance 100 80 60 40 20 0 Time (hours) 100 1,000 10,000 100,000 Working time of the LED modules is 20,000 hours or 3 years. (cf. The mercury lamp of the microscope only has a few hundred hours.) Cost-beneficial and profitable LED light sources No requirement for the light alignment TouchBright LED Wavelengths Wavelength 365 nm 380 nm 405 nm 455 nm 470 nm 530 nm 590 nm 630 nm 660 nm 740 nm White 400 450 500 550 600 650 700 750 Available LED wavelengths as shown Supplying with any combination of the wavelengths listed Both small and big chips available 3

TouchBright X5 & X6 High-Performance LED-Excitation System Ordering Information Model No. Description TouchBright X5 / X6 system [ nn/nn/nn/nn/nn - - - nn ] [ nn/nn/nn/nn/m - - - nn ] TB-X5 / X6 (nn/nn/nn/nn/nn- - -nn) Numbers of LED modules [X5] Select 4 LED modules [X6] Select 5 LED modules nn wavelength 21. 365 nm (11W) 22. 370 nm (117W) 31. 405 nm (10W) 32. 430 nm (12W) 34. 470 nm (52W) 41. 505 nm (7.8W) 42. 530 nm (58W) 43. 560 nm (6.5W) 44. 590 nm (10W) 51. 630 nm (32W) 52. 660 nm (4.5W) 61. 700 nm (4W) 62. 740 nm (7.8W) 71. 810 nm (7.6W) 73. 850 nm (7.8W) 99. White (49W) Wave length of external LED Illuminator Select 1 LED module 99. White (50W, standard) (Any color of LED modules are available instead of white) External LED Y. With external LED N. Without external LED Microscope company N. Nikon O. Olympus Z. Zeiss L. Leica M. Motic C. Other W is watt, the value means maximum electric power consumption of each LED module. TB-X5-Z001 TB-X5-Z002 TB-X5-Z005-nn TB-X5-Z006-nn TB-X6-Z001 TB-X6-Z002 TB-X6-Z003 TB-X6-Z004 TB-X6-Z005-nn TB-X6-Z006-nn TouchBright X5 light source (4 LEDs as standard and 1 external LED) TouchBright X5 touchscreen remote control pad TouchBright X5 external LED illuminator (white) TouchBright X6 LED modules (nn: wavelength) TouchBright X6 light source (5 LEDs as standard and 1 external LED) TouchBright X6 touchscreen remote control pad TouchBright X6 liquid light guide TouchBright X6 collimator for the liquid light guide TouchBright X6 external LED illuminator (nn: wavelength) TouchBright X6 LED modules (nn: wavelength) nn is order number of each LED according to the wavelength. www.touchbrightled.com

TouchBright X3 High-Performance 3 LED- Excitation System TouchBright X3 (one illuminator, default type) TouchBright X3 (two illuminators, option) TouchBright X3 basically consists of a touchscreen control pad, an AC/DC adaptor and a LED illuminator. 1 channel 2 channels Connectable with maximum three LED illuminators to the touchscreen control pad Directly attachable to the microscope without a light guide Suitable for the fluorescence microscopes to use a white light for the transmission imaging and one or two wavelengths for the fluorescence imaging For more than a illuminator, the display program is easily changeable from its setting mode as shown in the photos) Connect illuminators to the touchscreen control pad using the extension connector All LED illuminators are controllable with common software packages (e.g. TTL, Nikon-NIS, Metamorph or Micromanager) 3 channels Brightest LEDs & power stability Long lifetime Wide range of the LED wavelengths Simple & convenient operation No warm-up and cool-down 0-100% intensity control Directly connectable or combining the illuminator to the microscope 2 wavelengths for the fluorescence excitation with TouchBright TMC Model No. Description Model No. Description TB-X3-10 (nn) TouchBright X3 system with 1 illuminator TB-X3-Z002 connector for 2 illuminators TB-X3-20 (nn/nn) TouchBright X3 system with 2 illuminators TB-X3-Z003 connector for 3 illuminators TB-X3-30 (nn/nn/nn) TouchBright X3 system with 3 illuminators TB-X3-Z004 (nn) LED illuminator TB-X3-Z001 touchscreen remote control pad TB-X3-Z005 AC/DC adaptor nn is order number of each LED depends on wavelength. 5

TouchBright TMC LED Light Combiner for TouchBright X6 & X3 Available Wavelength of TouchBright X3 Number (nn) Wavelength Number (nn) Wavelength Number (nn) Wavelength Number (nn) Wavelength 21 365 nm 41 505 nm 53 690 nm 72 830 nm 22 380 nm 42 530 nm 61 700 nm 73 850 nm 31 405 nm 43 560 nm 62 740 nm 74 870 nm 32 430 nm 44 590 nm 63 760 nm 75 890 nm 33 455 nm 51 630 nm 64 780 nm 34 470 nm 52 660 nm 71 810 nm 99 white TouchBright X3 provides high-power LEDs that satisfy the most of the wavelength ranges. TouchBright TMC 2 liquid light guides of the TouchBright X6 - A combiner, collimators, and dichroic mirrors 2 illuminators of the TouchBright X3 - A combiner and dichroic mirrors TouchBright TMC allows to use 2 wavelength-leds simultaneously with TouchBright illumination systems. TouchBright TMC consists of a combiner, a collimator, and dichroic mirrors Configuration can be different from each kind of TouchBright illumination systems. 2 wavelengths are simultaneously allowed. Provide high speed wavelength selections A combiner is directly attachable to 2 illuminators. For using more than 3 illuminators, combiners are serially connectable. (option) For liquid light guides, collimators are attachable to the combiner Model No. Description TMC-Z001 TMC-Z002 TMC-Z003 TMC-Z004 combiner collimator (for the fiber optic) adaptor between the microscope and the combiner dichroic mirror www.touchbrightled.com

TouchBright W-Series LED Excitation System for Commercial 96-Well Plates TouchBright T1 (straight glass light guide) TouchBright T1 (ring glass light guide) The TouchBright T1 basically consists of a controller, a touch screen control pad, and a light guide. Light guides are compatible with all microscope, and there are three types light guide: Straight light guide, gooseneck type light guide, and Ring type light guide. 1. Straight type: These light guides are used for point illuminated area. There are several size of inner diameter of glass fiber depends on LED chip size. 2. Gooseneck type: These light guides are for spot-on illumination, and can adjust their directions you desired, because the gooseneck consists of a metallic spring tube. They are also available in one-arm and two-arm versions. 3. Ring type: These light guides can be attached at the stereomicroscope objective or CCD camera directly. The TouchBright T1 can be supplied with any color of the wavelength listed. In case of white LED, it can provide 50W or 100W LED (Electric power consumption) The strength of Light can be adjusted conveniently by to the touch screen control pad, and they are possible to control by the common software packages such as Metamorph or Micromanager like other TouchBright systems. Model No. Description TB-T1-Z001 TB-T1-Z002 TB-T1-Z003 TB-T1-Z004 TB-T1-Z005 TouchBright T1 light source TouchBright T1 touchscreen remote control panel TouchBright T1 straight glass fiber light guide TouchBright T1 gooseneck glass fiber light guide TouchBright T1 ring glass fiber light guide Live Cell Instrument Co.,LTD A 404 Hagye Technotown, 10 Nowon-ro 15-gil, Nowon-gu, Seoul, South Korea (ROK) E-mail: info@chamlide.com, support@chamlide.com Website: www.touchbrightled.com