Moving from R&D to Manufacture
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1 Moving from R&D to Manufacture Clara Asmail Senior Technical Advisor NIST MEP SBIR National Conference Austin, TX November 13, Co0&list=UUelItQpbih_hBrNSA5cRZyw 2 1
2 About MEP Provide manufacturers with innovation services as well as access to public and private resources that enhance growth, improve productivity, and expand capacity. Nationwide Connect and Deliver network operating as a public-private partnership 60 MEP Centers with 373 field locations System wide, over 1,300 Non-Federal staff Contracting with over 2,300 third party service providers 3 *Based on FY2013 Client reported data. 4 2
3 MEP supports commercialization by connecting and assisting building manufacturing capability technical/engineering support partnering with manufacturers market intelligence supply chain management Manufacturing Questions Is manufacturing right for your company? When do you think about manufacturing? How does manufacturing relate to R&D activities? MEP field engineers can help with: Finding and refining your strategy Developing and controlling manufacturing processes 3
4 Manufacturing Strategies Required Investment, potential risk & skill levels Process Scaling Skills Mfg Skill & Expertise Equipment Capital Investment Sales & Distribution Manufacture In-House High High High High Manufacture & Assemble Med High Med High Manufacture Outsource Low Low Low High License Low Low Low Low 7 Basics for Technology Transition Productization: Converting the technology into product that will sell. Right features Manufacturable Right price/cost On-time to market Productization assistance from MEP centers includes Requirements definition and prioritization Product concept definition Product concept validation Guidance on design for manufacturability, cost, quality Guidance on processes to manufacture Development of a plan to productize the technology including guidance on project management and risk management. 8 4
5 Developing Manufacturing Processes Design for: manufacturability, assembly, cost, standardization, logistics Voice of customer Lean Product Development Scale up Vertical Integration supply chain development Quality Management Systems -- cgmp, AS9100 etc Supplier management Design for Manufacture and Assembly # parts Parts: modular, standard, multi-use, multi-function Fastener selection Streamline assembly Tolerance optimization Don t forget to design for maintenance and repair and disposal/recyling 10 5
6 Working with MEP as a commercialization assistance provider Initial contact through referral Assessment: informal walk-through, analysis of company current state & goals Identify issues, define proposed project(s) and approach Negotiate and sign contract fee $ Project execution by Center or partner After completion, 3 rd party follow-up and explore further growth opportunities Contact Information Clara Asmail Senior Technical Advisor Manufacturing Extension Partnership National Institute of Standards and Technology Office: Cell: asmail@nist.gov 6
7 SBIR-Driven Entrepreneurship Surviving the Phase I to Production Journey Robert E. Slocum PhD Founder 2014 Fall National SBIR-STTR Conference (Austin) Slocum Geophysics Polatomic, Inc. Legacy of Laser-pumped Helium 4 Magnetometers Developed and perfected the laser-pumped Helium 4 Atomic Resonance Magnetometer for MAD replacement on P-3 Anti-Submarine Warfare fleet Selected as Navy s next generation of Airborne MAD (MagEagle) Has only commercial Non-Magnetic Sensor and Platform Test Facility in US Currently Partnering with Boeing on Next Generation of MAD, launching an Un-manned Arial Vehicle (UAV) from a P-8 Anti-Submarine Aircraft Chapter 9: Helium Magnetometers Robert E. Slocum, Douglas D. McGregor, and Andy W. Brown Polatomic, Inc., Richardson, TX Chapter 14 Space Magnetometry B. Patton, R. E. Slocum, A. W. Brown, and E. J. Smith Cambridge University Press 2013 MagEagle UAV Slocum Geophysics 7
8 The Polatomic Helium 4 Magnetometer technology was developed from a family of Laser Magnetometer Systems for Airborne & Undersea Magnetic Detection. P-3C (NAVAIR) Polatomic CMDS (ONR & NAVAIR) Compact Magnetic Detection System Laser Space Mag - MLM (NASA) P8-A Poseidon Boeing MECC Team (ONR) Laser Scalar Gradiometer (NAVSEA) UHRAM (ONR & NSF) Slocum Geophysics 15 Five Entrepreneurial Stepping Stones to SBIR Success 1. Entrepreneur, know they self! (small company or large company person) Type 1 Charismatic Leader Type 2 The Organizer Type 3 The Problem Solver 2. The Entrepreneurial Team Assign meaningful, challenging tasks & value each person and their work. 3. Strategic Plan: Find a customer with a significant problem (who can write the check), provide an innovative solution & make the customer a hero! 4. Stay healthy! Stay ethical! Stay in in compliance with customers guidelines for business! 5. Treat the Governments representatives (auditors?) as a valued customer. Slocum Geophysics 8
9 SBIR Valley of Death and Beyond Avoiding a Painful Premature Company Death. Five Death Treats! 1. Industry Restructuring - Telecom Bubble Burst IPI Optical Isolators 2. Teaming with Under Resourced/Staffed Customer JUNO Mission to Jupiter Polatomic JUNO Scalar Helium Magnetometer 3. Government Bureaucratic SBIR Cowards Award P-3C DMAD on SBIR Track? Polatomic AN/ASQ-233 MAD Set 4. Customer Death Traps P-3C DMAD disappears in aircraft sunset zone Polatomic AN/ASQ-233 MAD Set 1. Selection for Award by Broke Sponsor Sequestration stalls new start Polatomic CMDS MAD System & Boeing MagEagle Unmanned ASW Aircraft Slocum Geophysics The Entrepreneur s Prayer: Who can help us? 9
10 Turning Fundamental Science Into a Commercial Water Toxicity Sensor Through the SBIR Program Mike Mayo President and Co-Founder mmayo@nanohmics.com (512) Early-Stage Technology Development R&D Services Physical/electromagnetic modeling Sensors/diagnostics Analytical characterization Instrumentation Embedded systems/layout Mechanical/industrial design Core Capabilities Electro-Optics Novel Materials Instrumentation Engineering Sensors and Diagnostics Founded: 2002 Staff: 25 scientists/engineers Facility: 12,500 sq. ft
11 Initial Solicitation in 2003 A system for continuous monitoring of airborne chemical toxins utilizing Electric Cell-substrate Impedance Sensing (ECIS) technology 21 Timeline Initial effort began in January, SBIR programs were leveraged to develop the fundamental technology Development has been in Phase III funding since 2011 Platform is approaching Milestone C in the Army procurement cycle 22 11
12 Can toxins be detected in water by ECIS with a portable handheld unit? 23 What type of cells will work? Bovine Endothelial Responsive to toxins Require 37 C operation High Maintenance Xenopus(Frog) Melanophore Responsive to toxins 25 C operation Requires little maintenance Optical response 24 12
13 Rainbow Trout Gill Cells 25 C Operation Responsive to toxins Requires little maintenance Long term storage > 12 months 25 Cartridge and Test Procedure Development 26 13
14 Field Instrument Development 27 Phase III 28 14
15 Subsidiary Founded in Product Certification 3 rd party toxicant testing EPA (spring 2014) User training/verification Ft. Sam Houston, TX (May 2014) Environmental testing to MIL-810G standard Ft. Detrick, MD (June 2014) 30 15
16 Production Facility in Austin Metal deposition, photo lithography, and robotic assembly for biochip construction Cell culture facilities for maintaining cell cultures and loading biochips Current production rate is 100 biochips/week Process and automation improvements are currently under development 31 Production Order 32 16
17 What Next? Filling a 3000 unit order Partnership negotiations with Applied Biophysics Pursuing opportunities with water treatment facilities 33 Thank You Mike Mayo President and Co-Founder mmayo@nanohmics.com (512)
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