Modelling in Medicine and Biology

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1 Modelling in Medicine and Biology WITPRESS WIT Press publishes leading books in Science and Technology. Visit our website for the current list of titles. WITeLibrary Home of the Transactions of the Wessex Institute, the WIT electronic-library provides the international scientific community with immediate and permanent access to individual papers presented at WIT conferences. Visit the WIT elibrary at

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3 Modelling in Medicine and Biology Editors: C A Brebbia, Wessex Institute of Technology, UK

4 C A Brebbia, Wessex Institute of Technology, UK Published by WIT Press Ashurst Lodge, Ashurst, Southampton, SO40 7AA, UK Tel: 44 (0) ; Fax: 44 (0) witpress@witpress.com For USA, Canada and Mexico WIT Press 25 Bridge Street, Billerica, MA 01821, USA Tel: ; Fax: infousa@witpress.com British Library Cataloguing-in-Publication Data A Catalogue record for this book is available from the British Library ISBN: Library of Congress Catalog Card Number: The texts of the papers in this volume were set individually by the authors or under their supervision. No responsibility is assumed by the Publisher, the Editors and Authors for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions or ideas contained in the material herein. The Publisher does not necessarily endorse the ideas held, or views expressed by the Editors or Authors of the material contained in its publications. WIT Press Printed in Great Britain by Quay Digital, Bristol The material contained herein is reprinted from a special edition of Design & Nature and Ecodynamics, Vol.4 No.3. published by WIT Press. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the Publisher.

5 CONTENTS Preface... 1 Stress-strain distribution in the human stomach N.R. AKHMADEEV & R. MIFTAHOF... 3 A computer-assisted internal examination training system using both anatomical and virtual models A. DOI, K. NOGUCHI, K. KATAMACHI, T. ISHII, H. UNO, Y. MEGA & K. MATSUI A Numerical study of blood flow patterns in cerebral aneurysms and the causal relationship with platelet aggregation K. SHIMANO, T. KUDO, S.YOSHIMOTO, H. UJIIE & Y. ENOMOTO Effects of different types of input waveforms in patient-specific right coronary atherosclerosis hemodynamics analysis S.I. BERNAD, E.S. BERNAD, T. BARBAT, V. ALBULESCU & R. SUSAN-RESIGA The influence of heart stress on the brain: a preliminary study A.K. MACPHERSON, S. NETI, M. AVERBACH, P.A. MACPHERSON, C. CHUTAKOSITKANON & D. NATHANSON Mathematical aspects of the mechanics of laft ventricular contraction R.M. SHOUCRI Universal features in the laws of growth P.P. DELSANTO, A. GLIOZZI, D. ALEXANDRU IORDACHE & C. GUIOT Modeling stent expansion dynamics and blood flow patterns in a stenotic artery M.R. HYRE, R.M. PULLIAM & J.C. SQUIRE Blood flow under external strains: phenomenological approach, theoretical development and numerical analysis R. PAULUS, S. ERPICUM, B.J. DEWALS, S. CESCOTTO & M. PIROTTON Investigation of pulsatile flow in the upper human airways G. EITEL, T. SOODT & W. SCHRÖDER An innovative brace with pneumatic thrusts for scoliosis treatment M.G. ANTONELLI, P. BEOMONTE ZOBEL, P. RAIMONDI, T. RAPARELLI & G. COSTANZO The human lumbar vertebral body as an intrinsic, functionally optimal structure D.N.GHISTA,S.C.FAN, K.RAMAKRISHNA & I.SRIDHAR The optimal structural design of the human spinal intervertebral disc D.N.GHISTA, S.C.FAN, I.SRIDHAR & K.RAMAKRISHNA

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7 PREFACE The idea of preparing this volume originated from the ever increasing importance of computational modelling of complex problems in medicine. Considerable advances have been made in this area as demonstrated by the continued success of the International Conference on Modelling in Medicine and Biology organised by the Wessex Institute of Technology, the first of which was held in Southampton (1991), followed by Bath (1993), Milan (1995), Acquasparta (1997), Ljubljana (2003), Bologna (2005), The New Forest (2007), Crete (2009), and Riga (2011). The work reported at those meetings and the research carried out at our Institute indicated the increasing interaction and collaboration between medical and engineering scientists. The advances presented at some of our conferences are now being used in practice for a wide range of medical and surgical applications. The considerable improvements and evolution of the field led me to invite some of the best scientists who have participated in our conferences to write an article on their most recent research. This has led to thirteen outstanding articles published in this volume which encompass important areas of biomedical modelling. As the Editor of this book I am indebted to all authors for the quality of their contributions and I hope that the reader will find this volume useful. Carlos A. Brebbia Director Wessex Institute of Technology The New Forest, 2011

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