Simone Angela Winkler

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1 Physical Sci Res Assoc, Rad/Radiological Sciences Laboratory CONTACT INFORMATION Academic Contact Information Bio BIO I am a biomedical engineer specifically interested in finding diagnostic capabilities that advance medicine at the interface of engineering and the clinical/biological sciences. I am researching MR physics and engineering development for PET/MR and Ultra High-Field MRI with current and future specific focus on (1) pediatric whole-body cancer staging, (2) human connectome mapping for advanced understanding of neural connectivity in neurodegenerative and neurocognitive disorders. CURRENT ROLE AT STANFORD Research Associate HONORS AND AWARDS NIH K99/R00 award - "Human Connectome Mapping Using Ultra-High-Resolution MRI", National Institutes of Health - Career transition to academic independence ( ) 1st place in ISMRM annual meeting MR engineering competition, Toronto, Canada, ISMRM (2015) Magna Cum Laude Oral Presentation Award, ISMRM (2015) Stanford GRSL high-risk initiative grant: "Magnetogenetics: A Powerful Tool for Cancer Therapy", Stanford (2015) Collaborative Research Grant -- Harvard University / Massachusetts General Hospital, Burroughs Wellcome Fund ( ) Stanford RSL award, Stanford Radiological Sciences Laboratory (2013) Post-Doc Fellowship, NSERC ( ) Notable Services and Contributions towards the Advancement of IEEE, IEEE (2012) MTT-S Graduate Fellowship, IEEE (2009) 1st rank Québec-wide in Merit Scholarship Program for Foreign Students, FQRNT ( ) Numerous (5+) travel grants, various ( ) Best Paper Award, IEEE CCECE (2006) DOC-Scholarship, Austrian Academy of Science ( ) Completed studies in mechatronics below minimum time with distinction, JK University Linz (2005) Numerous (4+) awards for master thesis, Erwin Wenzel Foundation, BMGF, Tech2b, OeVE (2005) Page 1 of 5

2 EDUCATION AND CERTIFICATIONS Doctor of Philosophy, Ecole Polytechnique Montreal / Université de Montréal, RF/microwave engineering (2011) Master of Engineering, Johannes Kepler Universitaet Linz, mechatronics (2005) PROJECTS Acoustics and vibrations in head insert and body gradient coils for Ultra High-Field MRI Dielectric Shimming for Ultra High-Field MRI Combined RF-shim coil design for Ultra High-Field MRI In-vivo SAR mapping for Ultra High-Field MRI safety Magnetic Hyperthermia RF coil and electromagnetic modeling in MRI PATENTS Simone Winkler, Brian Rutt, Paul Picot, Michael Thornton. "United States In-Vivo Specific Absorption Rate Mapping using the Thermoacoustic Effect", May 7, 2014 Professional PROFESSIONAL AFFILIATIONS AND ACTIVITIES Chapter Head, ASCINA - Austrian Scientists & Scholars in North America ( ) Professional Engineer jun., Ordre des ingénieurs du Québec ( ) MR Engineering Study Group Trainee Chair, ISMRM ( ) Educational Session Organizer for the ISMRM, Singapore, ISMRM ( ) Fully licensed professional engineer, P.Eng., Professional Engineers Ontario ( present) Member, International Society for Magnetic Resonance in Medicine (ISMRM) ( present) Chair, IEEE Women in Engineering Montreal ( ) Member, IEEE ( present) Member, Austrian Academy of Science ( present) Chair, OeH Erstsemestrigentutorium (Austrian academic association - chapter for new student support) ( ) Steering Committee Member, IEEE International Microwave Symposium 2012 ( attendees) ( ) Reviewer, Artech House Book Publishers ( present) Publications PUBLICATIONS A Novel Performance-Prediction Model of Subharmonic Self-Oscillating Mixers 12th International Symposium on Antenna Technology and Applied Electromagnetics (ANTEM) and Canadian Radio Sciences (URSI/CNC) Accurate Vibroacoustic Simulations in High Performance Gradient Coils A Novel Multiple-Element Phased High-Order Subharmonic Self-Oscillating Mixer for Millimeter-Wave Receivers, Han, L., Wu, K., Stelzer, A. Comparison of new element designs for combined RF-Shim arrays at 7T, Stockmann, J., Warr, P. A., Keil, B., Watkins, R. P., Wald, L. L., Rutt, B. K. Page 2 of 5

3 Voltage controlled oscillator with frequency tripler in MHMIC technology for V-Band applications Hofmann, M.,, Wu, K., Koelpin, A. A Traveling-Wave Approach to Acoustic Noise Reduction in MR Gradient Coils A Novel Balanced Third and Fourth Harmonic Self-Oscillating Mixer with High Conversion Gain 36th European Microwave Conference Optimized Fast High-Resolution Whole-Body Imaging Protocols for Clinical Oncologic PET/MRI, et al 7T Diffusion Tensor Imaging of High Mechanical Stress Achilles Tendon-to-Bone Interface, et al Direct SAR Mapping by Thermoacoustic Imaging: Experimental Proof-of-Concept, Picot, P., Thornton, M., Rutt, B. K. Measurement and Modeling of LNA Based on Load-Pull System Zeng, X. B.,, Wu, K., Ye, Y., Liu, T. J., He, J. M. Optimized Dielectric Shimming in High-Field Magnetic Resonance Imaging: A Theoretical Approach, Sbrizzi, A., van den Berg, C. A., Luijten, P. R., Rutt, B. K. The Open Source Imaging Initiative Winter, L., Han, H., Barghoorn, A., Hoffmann, W., Hetzer, S.,, Wald, L. L., Webb, A., Blumler, P., Niendorf, T. A Novel Hybrid Analysis Approach for Subharmonic Self-Oscillating Mixers Combining Volterra Series and Conversion Matrix Methods 37th European Microwave Integrated Circuit Conference 2007 Vibroacoustic Noise Reduction in High Performance Head Gradient Coils Using Ceramic Inserts A Novel Polarization Rotating Frequency Selective Surface Based on Substrate Integrated Waveguide, Hong, W., Bozzi, M., Wu, K. Self-Oscillating Mixing Technique and its Application to Low-Cost Receiver Architectures IEEE Canadian Conference on Electrical and Computer Engineering CCECE 2006 : Modular And Versatile Multi-Row Transmit Array Based On A Novel Decoupled Coil Element Stara, R.,, Watkins, R. D., Retico, A., Tosetti, M., Rutt, B. K. Practical Methods for Improved B1 -Homogeneity in 3T Breast Imaging, Rutt, B. K. Time-Domain Microwave Cancer Screening: Optimized Pulse Shaping Applied to Realistically Shaped Breast Phantoms Porter, E., Santorelli, A.,, Popovic, M. Novel Compact and Broadband Interconnects based on Ridge Substrate Integrated Waveguide Bozzi, M.,, Wu, K. Singly Balanced Mixer Using Substrate Integrated Waveguide Magic-T Structure Han, L., Wu, K., A Study on Frequency Scalability for Integrated Imaging Radiometer Receivers Based on Subharmonic Self-Oscillating Mixers International Symposium on Signals, Systems, and Electronics (ISSSE) 2007 Page 3 of 5

4 Lorentz Damping and the Field Dependence of Gradient Coil Vibroacoustics Open Source Imaging Initiative (OSI²) Update and Roadmap Winter, L.,, et al Direct SAR Mapping by Thermoacoustic Imaging: A Feasibility Study, Picot, P., Thornton, M., Rutt, B. K. Flip Angle Inhomogeneity Constrained ptx Pulse Design for Minimum Peak Local SAR Pendse, M.,, Rutt, B. K. Recent Progress in Ultra-Wideband Breast Cancer Detection, Porter, E., Santorelli, A., Coates, M., Popovic, M. A Novel Technique for Millimeter-Wave Receivers Using Multiple-Element High-Order Subharmonic Self-Oscillating Mixers 2008 Global Symposium on Millimeter-Waves, Han, L., Wu, K., Stelzer, A. A Novel Hybrid Analysis Approach for Subharmonic Self-Oscillating Mixers Combining Volterra Series and Conversion Matrix Methods Proc. 37th European Microwave Conference 2007 A Novel Balanced Third and Fourth Harmonic Self-Oscillating Mixer with High Conversion Gain 9th European Wireless Technology Conference Gradient and shim technologies for ultra high field MRI. NeuroImage, Schmitt, F., Landes, H., DeBever, J., Wade, T., Alejski, A., Rutt, B. K. On the accurate analysis of vibroacoustics in head insert gradient coils. Magnetic resonance in medicine, Alejski, A., Wade, T., McKenzie, C. A., Rutt, B. K. Direct SAR mapping by thermoacoustic imaging: A feasibility study. Magnetic resonance in medicine, Picot, P. A., Thornton, M. M., Rutt, B. K. On the Accurate Analysis of Vibroacoustics in Head Insert Gradient Coils Magnetic Resonance in Medicine Practical Methods for Improving B-1(+) Homogeneity in 3 Tesla Breast Imaging JOURNAL OF MAGNETIC RESONANCE IMAGING, Rutt, B. K. 2015; 41 (4): Optimized Dielectric Shimming in High-Field Magnetic Resonance Imaging: A Theoretical Approach Scattering by Aggregates on Surfaces, Sbrizzi, A., van den Berg, C. A., Luijten, P. R., Rutt, B. K. edited by Wriedt, T., Eremin, Y. 2014: A Low-Power Third-Harmonic Self-Oscillating Mixer Using Multi-Harmonic Load IEEE Microwave and Wireless Component Letters Chiu, L.,, Xue, Q., Chan, C. H., Wu, K. 2012; 22 (7): Passive Millimeter-Wave Imaging Based On Subharmonic Self-Oscillating Mixing PhD Thesis. Ecole Polytechnique Montreal. Page 4 of 5

5 2011 Broadband and Compact Ridge Substrate Integrated Waveguides IET Microwaves Bozzi, M.,, Wu, K. 2010; 4 (11): Polarization Rotating Frequency Selective Surfaces Based on Substrate Integrated Waveguide Technology IEEE Transactions on Antennas and Propagation, Hong, W., Bozzi, M., Wu, K. 2010; 58 (4): Ultra-High-Order Self-Oscillating Mixers based on a Multiple-Element Technique Electronics Letters 2009; 45 (25) PAST Passive Adaptive Imaging System for Transportation European Microwave Week 2008, Montagna, M Integrated Receiver Based on a High- Order Subharmonic Self-Oscillating Mixer IEEE Transactions on Microwave Theory and Techniques 2007; 54 Research and Development of Innovative Millimeter-Wave Imaging Systems Austrian Academy of Science 2006 Self-oscillating mixing technique and its application to low-cost receiver architectures IEEE Canadian Journal of Electrical and Computer Engineering 2006; 31 (4): Design of a Novel Balanced High-Order Subharmonic Self-Oscillating Mixer Electronics Letters 2006; 42 (24): High-Speed DDS-controlled radar system for the identification of Surface Acoustic Wave Tags during translational motion Master Thesis. Johannes Kepler University of Linz, Austria Auswertung und Ansteuerung eines FSCW-Radars zur Codeidentifikation von SAW-Tags Bachelor Thesis. Johannes Kepler University of Linz, Austria Spezielle Relativitätstheorie: Eine Auseinandersetzung mit Einsteins Originalarbeit, 1905 Scholarly thesis. Austria Page 5 of 5

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