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Transcription:

Medical Intelligence: Big Data, Predictive Analytics, Machine Learning, and Artificial Intelligence Anthony C. Chang, MD, MBA, MPH Chief Intelligence and Innovation Officer Children s Hospital of Orange County Medical Director, Sharon Disney Lund Medical Intelligence and Innovation Institute Honors Cooperative Program in Biomedical Informatics/ Artificial Intelligence

Artificial Intelligence

ANTHONY CHANG

Artificial Intelligence Artificial Intelligence in Medicine ( Medical Intelligence )

Missing Data

Unstructured Data

Excessive Data

Future Data

Genomic Medicine: Next Generation Sequencing

Precision Medicine: Continuous Data From Birth Nicholson J et al. Discovery Medicine, 7/2009.

PharmacoGenomic s: Personalized Medicine

Internet of EveryThing Patient Care Data Continuum

Little Information

Disparate Information Knowledge and Intelligence Network Disparate types of information are linked into multiscalar, multilateral, multidimensional relationships

The end of theory: The data deluge makes the scientific method (randomized controlled trials) obsolete. Chris Anderson, Wired

Algorithms

Big Data

Computational Power

Cloud Computing

Cognitive Computing: Natural Language Processing

Data Mining: New Knowledge from Big Data

Deep Learning: Machine Learning/ Neural Networks

Do We Humans REALLY Need AI?

The Artificial Intelligence Brain

EME STREAMING ANALYTICS ARCHITECTURE Patient Bedside Monitoring Network Hospital Network ICU Monitors Med Surg Monitors Excel Medical BedMasterEx & BedComm IBM Infosphere Streams Various dashboards or notifications for clinicians & investigators OR Monitors ED Monitors Telemetry System Ancillary Monitoring Devices (vents, oximeters, video, etc) Hospital EMR and other data sources

The Artificial Intelligence Brain

The Artificial Intelligence Brain

Acquiring real-time / replay SQL/NoSQL/HTTP BMEX Runtime SQL Server Adaptation Layer Analytical Layer Delivery Layer InfoSphere Streams

The Artificial Intelligence Brain

The Artificial Intelligence Brain

The Artificial Intelligence Brain

function newimg = myconv2(img, kernel) newimg = zeros(size(img)); imgrow = size(img,1); imgcol = size(img,2); shift = (size(kernel,1)-1)/2; % maximum of how far we may go past border of img for row = 1:imgRow for col = 1:imgCol newimgval = 0; for x = -shift:shift for y = -shift:shift newrow = row - x; if (newrow < 1) continue; elseif (newrow > imgrow) continue; end newcol = col - y; if (newcol < 1) continue; elseif (newcol > imgcol) continue; end newimgval = newimgval + img(newrow, newcol)*kernel(x+shift+1,y+shift+1); end end newimg(row,col) = newimgval; end end

The Artificial Intelligence Brain

The Artificial Intelligence Brain

Cortical Infrastructure

Cortical Infrastructure

BioIntelligence Framework

BioIntelligence Framework: A Living Expert Neural Network

Making the visible invisible

Making the invisible visible

HyperGraph Architecture

Intelligence-Based Medicine

Intelligence-Based Medicine

Intelligence-as-a- Service (IaaS)

Collective SuperIntelligence

VERY SPECIAL THANKS TO: Sharon Disney Lund Medical Intelligence and Innovation Institute (MI3)

VERY SPECIAL THANKS TO: Sharon Disney Lund Medical Intelligence and Innovations Institute (MI3) Honors Cooperative Program in Biomedical Informatics/ Artificial Intelligence

VERY SPECIAL THANKS TO: Sharon Disney Lund Medical Intelligence and Innovations Institute (MI3) Honors Cooperative Program in Biomedical Informatics/ Artificial Intelligence and Scientist-in-Residence and Computer Science Department

VERY SPECIAL THANKS TO: Sharon Disney Lund Medical Intelligence and Innovations Institute (MI3) Honors Cooperative Program in Biomedical Informatics/ Artificial Intelligence and Scientist-in-Residence and Computer Science Department