MacroPATH The new line of Digital Imaging Systems for Grossing

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MILESTONE H E L P I N G P A T I E N T S MacroPATH The new line of Digital Imaging Systems for Grossing If the dimensions of the specimen are not recorded, the key section not taken, and the proper special studies not performed at the time of the initial gross examination, the chances of acquiring this information may be lost forever * Surgical Pathology, tenth edition J.Rosai

MacroPATH pro A picture is worth 1 3 4 6 7 5 2 A new innovative tool for macro digital imaging acquisition. With a superior quality camera, improved specifications and built-in LED illuminator, the MacroPATH pro is the ideal solution for high quality photography of gross specimens. The user oriented system enables quick and easy capture, annotation and storage of images for diagnostic support, scientific publications, teaching purposes and research documentation. Users can augment their patient image cases with video and audio capabilities included with the system. The MacroPATH pro camera allows flexibility for installation in all working conditions. Grossing stations, photographic stands, dissection tables, and ventilation hoods are all supported platforms. In addition, our standalone system with its uniquely designed ergonomic stand is a great solution for laboratories with space constraints. Technical specifications 1 - MacroPATH pro Camera Splash resistant camera enclosure with built-in LED illuminator 10 x optical zoom with auto-iris and auto-focus Resolution: up to 10 Mpixels, 15 fps, CMOS sensor Complete with +1, +2 and +4 close up lenses Live resolution: 960X680 uncompressed Adjustable white balance 2 - Foot Pedal Control Medical grade foot pedal controls zoom and save functions 3 - Point-of-care (POC) Control Terminal* 17 TFT 1280X1024 Touch Screen Control terminal Intel Core 2 Duo Processor T7400 2.0 GHZ 4 GB DDR2 RAM - 500 GB Hard Disk 5000 RPM 24X7 Spill and dust resistant front panel IP 65 - NEMA 4 complaint 4 - Metal table top camera stand 5 - Waterproof IP-68 Keyboard* 6 - Wired microphone 7 - Bar code reader* * Options, CPU specifications are subject to change without notice

a thousand words MacroPATH lean 3 1 4 6 7 5 2 An ideal solution for laboratories requiring a lean macro imaging system in multiple workstations. A small form factor, fixed objective lens and digital zoom all contribute to ease of installation and use in the most space constrained environments. Quick image capture and minimization of operator interaction both contribute to efficient processing of patient cases. Robust image annotation features provide pathologists the ability to build the full context of the patient case, thereby enhancing their diagnostic report. The MacroPATH lean camera offers several installation options. Grossing stations, current photographic stands or stand- alone systems can be easily configured for use. Technical specifications 1 - MacroPATH lean Camera Camera with adjustable focus and iris Resolution: up to 10 Mpixels, 15 fps, CMOS sensor Digital zoom Focal length: 12mm Iris range: 1.4 - closed 2 - Foot Pedal Control Medical grade foot pedal controls zoom and save functions 3 - Point-of-care (POC) Control Terminal* 17 TFT 1280X1024 Touch Screen Control terminal Intel Core 2 Duo Processor T7400 2.0 GHZ 4 GB DDR2 RAM - 500 GB Hard Disk 5000 RPM 24X7 Spill and dust resistant front panel IP 65 - NEMA 4 complaint 4 - High-impact polymer camera stand 5 - Waterproof IP-68 Keyboard* 6 - Wired microphone 7- Bar code reader* * Options, CPU specifications are subject to change without notice

MacroPATH is simplicity Enter specimen/patient data by keyboard or scan bar code. Program automatically opens. 1D 2D 1 - Start A CASE Capture real size, close up images of excised specimens in rapid sequence. Saved images appear as thumbnails on the right side of the screen. 2 - SAVING IMAGES 6 - REPORTING The ability for MacroPATH to easily capture, annotate, and store high quality images enables the building of enhanced patient reports with additional context for the clinician, surgeon and oncologist. 5 - DOCUMENTING Eliminates potential mismatching of cassettes labeled/number of blocks, sampled tissues. Valuable documentation in educational/training environment.

NEW FEATURES Image/Case database Easily search and access patient cases by standard and/or custom tag identifiers Select desired image. Choose appropriate Sizing tool (linear, area, perimeter) and select area of interest. The tool will automatically calculate the length or area of your annotation. 3 - MEASURING Prostate dissection Quickly annotate prostate cross sections saving valuable time 4 - SECTIONING Pick the image of interest. Select Sections icon. Draw on specimen to indicate sampled areas. The tool will label sequentially. Preset text Quickly access routinely used terms through pre-built menus Video and audio Complement your case with video and mp3 audio

MacroPATH is flexibility MacroPATH pro and MacroPATH lean offer unique solutions to ensure comfort for all users in every working condition. The system can be configured to operate as stand-alone, on photographic stand or fully integrated in grossing station. Stand-alone operation Grossing station Photographic stand Accessories USB barcode reader Floor type terminal holder Wet area cutting board for a high contrast background Waterproof keyboard with IP-68 dust/water protection PTFE washable touch pen

Stand-alone system MacroPATH is integration In addition to stand-alone operations, MacroPATH can interface with a PACS or LIS through dedicated or TWAIN protocols. Saved locally Saved in a network location Interfacing with LIS (Laboratory Information System) or PACS Use as TWAIN device 4 1 3 2 MacroPATH acts as a secondary application to the LIS. Patient case identifier is held by LIS. 1 LIS launches MacroPATH. 2 User completes image acquisition and annotation. 3 Assets are transferred to the LIS. 4 Additional operations by the user (image manipulation, selection of images for inclusion into patient reports, etc). MacroPATH acts as a secondary application launched via TWAIN protocol. Multiple images are taken and manipulated and then transferred to the primary application (LIS or other program with TWAIN import capability). MileVIEWER: the state-of-the-art digital system for telepathology MileVIEWER MacroPATH can be connected via internet to share all relevant information of the grossing procedures with remotely located pathologists through the new MileVIEWER software package. Mobile device Highest security standard MacroPATH INTERNET Desktop The MacroPATH remote connection features completely secure data channels with key exchange and AES (256 Bit) session encoding, the same security standard used by https/ssl. Laptop

MacroPATH is digital imaging Milestone is committed to developing and introducing forward thinking digital systems to the macro imaging market. Since 1996, the MacroPATH has led the way in enabling pathologists and assistants to standardize and visually document grossing of patient specimens. The new, fourth generation of Milestone s Macro Digital Systems, MacroPATH pro and MacroPATH lean, represents the cutting edge technology of 16 years of experience gained by hundreds of installed units worldwide. The MacroPATH 5 software is the best expression of a userfriendly graphical interface for easy, simple and lean use. Editing Tools Case Images User-friendly graphical interface Customizable area and fonts dimensions Camera live video Images saved with case ID in up to 3 folders Images saved locally or over the network Automatic sizing (linear, areas, perimeter) Automatic sequencing during block labeling Additional digital zooming on saved images Reporting capabilities with images built in Case database MP3 audio and Mpeg video capturing Text insertion with pre configured notes Utility Bar FEATURE Auto-focus/auto-light adjusting camera Simplified user interface LIS integration options (including TWAIN) Automated Image Management (non-lis) Multiple Mounting Options BENEFIT Improve efficiency by reducing manual intervention Easy to adopt and train new personnel Quickly transfer patient case images into your system of choice Save time while standardizing file organization and naming Enables flexibility in camera positioning MILESTONE MILESTONE Srl - Via Fatebenefratelli, 1/5-24010 Sorisole (BG) - Italy Tel: +39 035 4128264 - Fax: +39 035 575498 www.milestonemedsrl.com - email: medical@milestonesrl.com UNI EN ISO 9001: 2008 / UNI EN ISO 13485:2004 CERTIFIED In your country: H E L P I N G P A T I E N T S MILESTONE MEDICAL TECHNOLOGIES, INC. 6475 Technology Avenue, Suite F, Kalamazoo, MI 49009 - USA Tel: 269-488-4950 - Toll-free: 866-995-5300 - Fax: 269-488-4949 www.milestonemed.com - email: info@milestonemed.com CAT332EN-002