Model BPG-1P Biphasic Pulse Generator

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MicroProbes for Life Science Model BPG-1P Biphasic Pulse Generator Owner Manual Version: January, 2018 18247-D Flower Hill Way Gaithersburg, MD 20879 Phone: +1 301 330-9788 Fax: +1 301 330-9667 w w w.microprobes.com support@microprobes.com

Table Of Contents Description 3 Specifications 4 Control Layout Front Panel Measurement Display 5 5 6 Setting up for Use 7 About Illogical Settings Using the BPG-1P 8 9 Servicing the BPG-1P 11 Certification 11 Warranty 12 Service 12 Contact information 12 2

Description The BPG-1P is a portable pulse generator for neuroscientific experimentation. The unit is lightweight, versatile and battery operated for convenience. It can generate single or dual pulses of either positive or negative polarity as well as alternating positive and negative pulses. The output amplitude is adjustable from 0 Volts to +/ 10V peak. It operates in either free-running mode or triggered mode. When in triggered mode, a single pulse train will be generated for each trigger pulse inputted or for each press of the manual trigger button. To trigger a pulse-train1, either press the manual trigger button or connect a signal 2.5V (minimum) to the ext. trig port. The output can also be gated (allowed) only when an externally connected signal is above the 2.5 Volt threshold. Like our legacy BPG-1, if a pulse-train (single or double pulse) began and the gate signal goes low, the BPG-1P will complete the (already started) pulse-train. When first powered on, the graphic liquid-crystal display turns on and shows the waveform selected, pulse width, interval (for double pulses), period (when in free run mode) and the battery status. When in triggered (TRIG D) mode, the delay time (trigger pulse start of pulse-train) is also displayed. All parameters are user adjustable by pressing one of the four next parameter, last parameter, increment, or decrement buttons. The signal is present at the output connector after the output signal is pressed (Output: On displayed on LCD). 3

Specifications Pulse Width Accuracy of Pulse width Period Accuracy of period Interval Delay (start of train after trigger) Waveforms Output Voltage (peak) Rise Time/Fall Time Input impedance (trig & enable) Minimum Trigger Pulse Width Power Current Draw Battery Life Dimensions Weight 10us to 980ms in 4 ranges 10us 99us - 100us 990us, 1ms 99ms - 100ms 980ms within 1 percent of selected value 1ms to 990ms in 3 ranges 1ms 9.9ms - 10ms 99ms, 100ms 990ms within 1 percent of selected value 10us to 99ms in 4 ranges 10us 99us - 100us 990us, 1ms 9.9ms - 10ms 99ms (time between two double pulses) 10us -> 990ms in 4 ranges Single Positive, Single Negative Alternating negative and positive, Double positive or Double negative continuously variable from 0 to 10V (+/-) < 50 ns from 0 to +10V or 0 to -10V 100 kilo Ohms 5 microseconds (2) 3.6 Volt lithium-metal C-cell batteries 73mA (typical) >90 hrs. Continuous duty (typical) 9 (22.9cm) W x 3.5 (8.9cm) H x 7.5 (19cm) D 1 lb. (454mg) 4

Control Layout 1 4 9 11 BPG-1P BIPHASIC PULSE GENERATOR LAST NEXT PARAM SELECT AMPLITUDE EXT TRIGGER 2 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. MANUAL GATE OUTPUT TRIGGER 3 5 6 MADE IN THE USA 7 8 OUTPUT 10 Power Button Ext. Trigger Input Gate Input Measurement Display Output Enable Manual/Trigger Button Last Button Next Button Mode Toggle Signal Output Amplitude Knob 5

Measurement Display 1 2 3 5 6 8 4 1. 2. 3. 4. 5. 6. 7. 8. Battery status Waveform Period Triggered/free run mode Pulse-width Interval (double pulses) Delay (when in triggered mode) Output status (on or off) External Gate input duration Period pulse interval pulse width Triggered delay Trigger Pulse 6

Setting up for Use After turning on the power by pressing the power button and holding it for ½ second, the arrow points to the waveform as shown in panel display above. This indicates the waveform is selected and pressing the up or down buttons will change the selected waveform. Press the up or down buttons until you see the waveform that you want. Press the Next button and the arrow now points to the mode (free run or triggered). Press up for free run and down for triggered. Press the Next button again and the arrow will point to the period range. Here you will select the range of the period. Press the up or down buttons to select the range of the period you want. Press the Next button again and the arrow will point to the period. Press the up or down buttons to adjust the period. Press the Next button again and the arrow will point to the pulse-width range. Here you will select the range of the pulse-width. Press the up or down buttons to select the range of the PW that you want. Press the Next button again and the arrow will point to the PULSE. Press the up or down buttons to adjust the pulse-width. Pressing the Next button again will select the interval range. Again, choose the range by pressing either the up or down buttons. The Next button will the move the arrow to the interval. Again, use the up or down buttons to adjust the interval. If you want to go back and change a previously set parameter, press the Last button until the arrow points to the parameter that you wish to change. If you shut the unit off, it will recall the last settings upon power up. 7

Press the Run button and the waveform will be present at the output. While running, the waveform cannot be altered (except for the amplitude). If you wish to trigger the start of pulse trains from an external source (for synchronization, as an example), this is accomplished by connecting a positive going trigger pulse to the external trigger input and having already selected triggered mode. The trigger pulse must be at least 2us in duration to trigger the BPG-1P but we recommend 5us (or greater). The BPG-1P uses a microcontroller to operate the display, enable the operator s button switches and generate the different waveforms. The firmware has internal routines that prevent the operator from entering values that are illogical. About Illogical Settings An example of an illogical input would be for example, a pulse-width or pulse-widths (double pulse waveforms) and an interval whose total time is greater than the period. It is impossible to enter something like that as the BPG-1P will not allow it. Also, for example, assume that you have selected a single pulse waveform of say 5ms and a period of 10ms. This would work fine but if you attempt to change the waveform to a double pulse, the firmware will not allow it. This is because two pulses of 5ms each plus any interval exceeds the period (in this example, 10ms). Total Pulse-width(s) + Interval must be < the Period. In a case like the one above and you want to change to a double pulse waveform, you should first increase the Period Range to maximum. This will allow you to change from a single pulse to a double pulse. Next select the desired waveform. Then adjust the pulse-widths and intervals. After these have been set, go back and set the period range and period. 8

Using the BPG-1P Once the parameters are set and you re ready for the signal, press the output button and you ll see the words Output: On have replaced Output: Off. The output is now active and if the unit is in free run mode, a repeating pulse or pulse pair is present on the output. If the unit is in Trig d mode, an output pulse or pulse pair will be present at the output after receiving an externally applied trigger pulse. In triggered mode, only one pulse or pulse pair is generated for each trigger pulse present at the Ext Trigger port. A manual trigger will also generate a single pulse or pulse pair with each press of the manual trigger button. For safety reasons, when switching from triggered mode to free running mode, the period will change to 990ms but can be changed. This is to reduce the chance of inadvertently selecting a high pulse rate after having used the triggered mode. The Gate input also allows the user to enable or disable the output by applying a positive voltage to the Gate input. The positive voltage can be anything from 3 to 50 Volts. Apply a low voltage (0 to 0.7 Volt) to the Gate port to disable it. If a waveform has already started when the Gate signal goes low, the waveform will complete its cycle before stopping. This is especially helpful when using bi-phasic waveforms as the number and duration of positive and negative pulses will be equal. EXAMPLE 1: Desired Period (or 1/F) = 20ms (Since you have selected a period, you must first set the BPG-1P to free running as opposed to triggered.) Desired Waveform = biphasic negative then positive Desired Pulse width = 500us Desired Interval (time between the pulse pairs) = 300us Procedure: Press and hold the power button until the display comes up. 9

Using the BPG-1P 1. 2. 3. 4. 5. Notice that the small arrow points to the waveform. Press the or button until the desired waveform is displayed. In this example, you want the negative pulse followed by the positive pulse. Press the parameter Next button and the arrow will point to either triggered or free run. If it points to triggered, press the button and the arrow will point to free run. (pressing the button selects triggered mode). Press the parameter Next button and the arrow points to the period Range. Press the or button until 10-99ms is displayed. Press the parameter Next button and the arrow points to Period. Here you will set (using the or buttons) until the period = 20ms. Press the parameter Next button and the arrow points to pulse-width Range. As before, press the or buttons until the PW Range = 100-990us. 6. Press the parameter Next button and the arrow points to Pulse. Press the arrows until the Pulse = 500us. or 7. 8. 9. Press the parameter Next button and the arrow points to interval Range. As before, press the or buttons until the interval Range = 100-990us. Press the parameter Next button and the arrow points to Interval. Press the or arrows until the Pulse = 500us. Adjust the 10-turn knob until the desired peak voltage is set. 10

Using the BPG-1P 10. In the lower right of the display, you ll see Output: Off. Press and hold BRIEFLY the output button until the display changes to Output: On. The output is now present at the output BNC connector. 11. Press the Output button to stop the output or if the experiment is complete, press the Power button. When the unit switches off, it first saves the parameters that were last set. This saves time when an experiment is to be performed several times with the same parameters. When the output is ON, the parameters and buttons are disabled. The only controls that are useable now are: Amplitude, Output (ON/OFF) and Power (ON/OFF). Servicing the BPG-1P The batteries are the only items that are user serviceable. When the battery level indicator shows only one bar, it s time for a fresh set of batteries. To replace them, unscrew the cap on the rear of the unit and remove the two c-cells. These are 3.6V lithium-metal batteries so don t try to use 1.5Volt batteries as the unit will not function. Be sure to install them with the positive terminals facing outward. Certification Microprobes for Life Science certifies that this instrument has been tested and inspected thoroughly and was found to meet all published specifications before shipment from the factory. 11

Warranty All Microprobes for Life Science products are warranted against defects in materials and workmanship for one full year from the date of delivery. Products that prove to be defective during the warranty period will be repaired or replaced without charge provided they are returned to the factory. No other warranty is expressed or implied. We are not liable for consequential damages. Service Microprobes for Life Science will provide for servicing and calibration after the warranty period for a reasonable service charge. The instrument should be shipped to the factory postage prepaid. There is a minimum service charge of one hundred dollars ($100.00) and all instruments will be repaired, calibrated and returned promptly. Please enclose a cover letter with the instrument explaining deficiencies and identify by serial number in all correspondence pertaining to any instrument. Contact Information MicroProbes for Life Science 18247-D Flower Hill Way Gaithersburg, MD 20879 Phone: +1 (301) - 330-9788 Fax: +1 (301) - 330-9667 support@microprobes.com www.microprobes.com Microprobes for Life Science Inc. 2018 All rights reserved 12