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Surgical Products New CONNECTING VISIONS

Connecting Visions Topcon and Oculentis - Partners in Intraocular Surgery Oculentis as a company stands for innovativeness, closeness to the customer and flexibility. These attributes have become part of its corporate culture. Oculentis develops, manufactures and distributes intraocular lenses, viscoelastics and other consumables for the ophthalmic surgeon. All products fulfill the highest of standards in safety and quality. Topcon, with its highly innovative line of diagnostic and surgical equipment, delivers the means and the ways to implement these high quality surgical products in your daily operating routine, thereby guaranteeing efficient patient throughput and optimal patient outcomes. Topcon and Oculentis are committed to enabling you to provide state of the art eye care for your patient. Intraocular lenses from Oculentis Oculentis is one of the few remaining independent manufacturers of high precision foldable acrylic intraocular lenses (IOL s) with their own research and development facilities. Oculentis also boasts one of the most modern and advanced manufacturing facilities for these IOL s in Eerbeek, The Netherlands. Automated IOL manufacturing Quality control

Intraocular lenses from Oculentis Proprietary manufacturing technology developed by Oculentis The heart of this manufacturing facility is the proprietary manufacturing process which is termed Sub-Micron-Lathing Technology (SML Technology). SML Technology allows for extremely precise optics and sharp contours without the need for polishing. This is the basis for the extreme precision and high reproducibility of complex optic designs. This precision is also instrumental in achieving the sharp, square edges necessary for preventing cell migration in the posterior capsule and therefore effectively delaying the formation of PCO. SEM image of LENTIS L-312 Hydrosmart Biomaterial Best of Both Worlds Hydrosmart is a material with high water content and hydrophobic surface properties, it therefore combines the best of both hydrophilic and hydrophobic materials. Its most important properties are: Hydrophobic surface Miyake-Apple posterior view of LENTIS L-303 Refractive index 1,46 ~25% water content Hydrophobic surface Ultrapure due to special purification No discoloration in the eye Very low incidence of PCO Hydrosmart is highly biocompatible and has clinically proven to be a very safe and effective material with more than 1 million lenses implanted in Europe alone. Blue light filtering Biomaterial Oculentis also offers in its LENTIS Select range of IOL's biomaterial with blue light filtering capability. The absorption values are ideally profiled for maximum transmittance of the visible light spectrum combined with optimal blocking of high energy light waves that may cause harm to the macula.

The LENTIS Product Range IOL Design Oculentis offers a variety of IOL designs to choose from. The most popular design is the open loop design as one piece (LENTIS L-302) or three piece (LENTIS L-402). The plate design (LENTIS L-303) offers the possibility to be implanted through a sub 2.0 mm incision and is therefore ideally suited for MICS techniques. LENTIS L-303 LENTIS L-302 LENTIS L-402 LENTIS aspheric IOL s also exhibit an additional 360º haptic-optic square edge barrier that thanks to the precision of SML Technology delivers an optimally effective prevention of secondary cataract formation (LENTIS L-312). LENTIS L-312 IOL Optics Aspheric Optics In standard spherical IOL s light rays entering at the periphery of the optic exhibit a higher refraction than light rays entering paraxially. This phenomena is called spherical aberration. With the new concept of adjusting the posterior central thickness of the IOL, an aspheric posterior surface is created. This assures that all light rays are virtually refracted equally in one focal point and therefore the IOL being virtually free of spherical aberration. MTF* spherical IOL (+22 dpt., 4mm aperture) standard optical quality MTF* aspheric IOL (+22 dpt., 4mm aperture) vastly improved optical quality The effect of this on the optical quality is clearly shown in this comparison between these two IOL's. The Modulation Transfer Function (MTF) is an indicator for the optical imaging performance of an IOL. The LENTIS aspheric optical design improves contrast vision, color perception, and still retains a comfortable depth of field. (LENTIS L-312) Toric Optics Toric IOL s are an increasingly important and reliable tool for the surgeon to treat corneal astigmatism during cataract surgery. LENTIS Unico (LU) offers a 100% customized compensation of virtually any corneal astigmatism. An IOL calculator form is provided for the surgeon in order to identify the right IOL parameters for the individual patient. Then the lens will be manufactured to order. The LENTIS Unico is available in the plate and the one piece open loop design. Both lens designs have clinically been proven to be rotationally stable, which is a necessary precondition for providing reliable correction of corneal astigmatism. The LENTIS Unico in plate design (LENTIS LU-313 T) can be inserted through sub 2.0 mm incisions (MICS) thus providing enhanced predictability and reproducibility by using astigmatism-neutral LENTIS Unico LU-313 T incisions. In addition to the astigmatism compensation on the anterior surface, the LENTIS Unico also exhibits an aspheric posterior surface further enhancing the optical image quality of the IOL. (see aspheric optics) * = MTF measurements made with model eye acc. to ISO 11979-2

Lens Delivery Systems & Consumables Lens Delivery Systems IOL handling and implantation is a crucial link in the cataract surgery quality chain. All LENTIS IOL s are offered with systems manufactured by Medicel AG of Switzerland. The Viscoject and Naviject systems can be ordered both in multi-use or single-use. Oculentis consumables product range A complete range of high performance viscoelastics, ultrapure vitreoretinal products and irrigating solutions is available covering every necessary aspect of intraocular surgery: Cooling Free* Viscosurgical Devices Visco 4500 dispersive viscoelastic solution of 2% hydroxypropyl methylcellulose available in sterile disposable syringes of 1,5 ml and 2,3 ml Vitreoretinal Products Vitreo Sil Ultrapure silicone oil for use as temporary or permanent intraocular tamponade for retinal detachment. Available in viscosities of 1000 and 5000 cps and in vials of 15 ml or syringes of 10 ml. Vitreo Deca 100% fluorinated perfluorocarbon for use as intraoperative device for the unfolding of the retina. Available in vials of 5 ml or 7 ml. Visco NaH 2.0 cohesive viscoelastic solution of 2% sodium hyaluronate of biofermentative origin available in sterile disposable syringes of 1,0 ml Visco HYAL 1.0 cohesive viscoelastic solution of 1% sodium hyaluronate of natural origin (rooster combs) available in sterile disposable syringes of 0,55 ml and 0,85 ml Visco HYAL 1.4+ - cohesive viscoelastic solution of 1.4% sodium hyaluronate of natural origin (rooster combs) available in sterile disposable syringes of 0,55 ml and 0,85 ml Irrigating Solutions BSS Irrigation solution for intra- or extraocular surgeries. Mimics the aqueous humor in ph-value, osmolarity and chemical composition. Available in 500 ml glass or plastic container. *All Viscoelastics can be stored at room temperature

Operation microscopes OMS 800/850 Series Ceiling version OMS-800 / 850 Pro Electromagnetic brakes and sophisticated electronics confer the OMS-800 Pro the flexibility to perform virtually any type of ophthalmologic surgical procedure. OMS-800 / 850 OFFISS OFFISS offers a new scope of possibilities in intravitreal surgery. Equipped with the OFFISS front lens mechanism, electromagnetic brakes and sophisticated electronics, this model is the highest standard for intra vitreal surgery, as well as other ophthalmic procedures. Floor stand version OMS 710 Series All purpose microscope covering both the Anterior and Posterior segment Unsurpassed image luminosity with the most natural color and improved Red Reflex. Superb optical performance thanks to its apochromatic optical system that affords bright, vivid images even with reduced illumination intensity. Protection from phototoxicity with low illumination levels and UV/IR cut filters. For technical specifications please see back cover

Additional Information

Specifications 800/850 OFFISS 800/850 PRO Type Magnification selection Eyepiece Binocular tube Objective lens Magnification indications Total magnification Maximum arm load Accessory capacity Power voltage Power input Illumination bulb Weight Offiss Magnetic locking Apochromat Dual focus system 6-18 kg 4,4 kg 250 kg Galileo type Continuous zoom 12.5X Parallel f = 200 mm 4.2 / 5 / 6 / 7 / 8 / 9 / 11 / 13 / 15 / 17 / 19 / 21 4.2X - 21X 6-18 kg 6,1 kg AC100-120 50/60Hz, AC220-240V 50/60Hz 280VA Halogen 100W 247 kg N/A Illumination angle all ±2 (±2,+4 ) / Yellow filter (+4 ) * OMS-800/850 OFFISS and Pro without "Dual Focus system" are also available. * 800 Floor stand version / * 850 Ceiling version 710 9,5-16 kg 5,5 kg 184/185 kg N/A N/A N/A 2,4 Dimensions OMS-800 Dimensions OMS-850 Dimensions OMS-710 Oculentis Topcon 1275 Subject to change in design and/or specifications without advanced notice. In order to obtain the best results with this instrument, please be sure to review all user instructions prior to operation. Topcon Europe Medical B.V. Essebaan 11; 2908 LJ Capelle a/d IJssel; P.O. Box 145; 2900 AC Capelle a/d IJssel; The Netherlands Phone: +31-(0)10-4585077; Fax: +31-(0)10-4585045 E-mail: medical@topcon.nl; www.topcon.eu Topcon España S.A. HEAD OFFICE; Frederic Mompou, 5; 08960 Sant Just Desvern; Barcelona, Spain Phone: +34-93-4734057; Fax: +34-93-4733932 E-mail: medica@topcon.es; www.topcon.es Topcon (Great Britain) Ltd. Topcon House; Kennet Side; Bone Lane; Newbury Berkshire RG14 5PX; United Kingdom Phone: +44-(0)1635-551120; Fax: +44-(0)1635-551170 E-mail: info@topcon.co.uk; www.topcon.co.uk Topcon Portugal Rua da Forte, 6-6A, L-0.22; 2790-072 Carnaxide; Portugal Phone: +351-210-994626 Fax: +351-210-938786 www.topcon.pt Topcon Danmark Praestemarksvej 25; 4000 Roskilde, Danmark Phone: +45-46-327500; Fax: +45-46-327555 E-mail: topcon@topcondanmark.dk www.topcondanmark.dk Topcon Scandinavia A.B. Neongatan 2; P.O. Box 25; 43151 Mölndal, Sweden Phone: +46-(0)31-7109200; Fax: +46-(0)31-7109249 E-mail: medical@topcon.se; www.topcon.se Topcon Italy Viale dell Industria 60; 20037 PADERNO DUGNANO; (MI) ITALY Phone: +39-02-9186671; Fax: +39-02-91081091 E-mail: topconitaly@tiscali.it; www.topcon.it Topcon Deutschland GmbH Giesserallee 31; D-47877 Willich, Germany Phone: +49-(0)2154-8850; Fax: +49-(0)2154-885177 E-mail: info@topcon.de; www.topcon.de Topcon Ireland Unit 276, Blanchardstown; Corporate Park 2 Ballycoolin; Dublin 15 Phone: +353-18975900; Fax: '+353-18293915 Email: medical@topcon.ie; www.topcon.ie Topcon S.A.R.L. HEAD OFFICE; 89, rue de Paris; 92585 Clichy, France Phone: +33-(0)1-41069494; Fax: +33-(0)1-47390251 E-mail: topcon@topcon.fr; www.topcon.fr TOPCON CORPORATION 75-1 Hasunuma-cho, Itabashi-ku, Tokyo 174-8580, Japan. Phone: 3-3558-2523/2522 Fax: 3-3960-4214 www.topcon.co.jp Topcon Polska Sp. z o.o. ul. Warszawska 23; 42-470 Siewierz; Poland Phone: +48-(0)32-670-50-45; Fax: +48-(0)32-671-34-05 www.topcon-polska.pl Item code: 5250371 / printed in Europe