3D OCT-2000 / 3D OCT-2000

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Specifications Observation & Photography of Fundus Image Scan Mode Observation Picture Angle Diopter Scale Range *** Operating Distance Photographable Diameter of Pupil Color, FA*, Red-free** Near IR Equivalent 0 (Digital Zoom ) -1D to +12D (in fundus photography) 0.mm (in fundus photography) :.0mm or more Small pupil diameter:.mm or more Optical Coherence Tomography FA D OCT-2000 / D OCT-2000 Observation & Photography of Fundus Image Scanning Range (On Fundus) (On Cornea) Scan Patterns Macula: D Scan (Recommended) Macula: Radial Scan Macula: Line Raster ****** Disc: D Scan Disc: Circle Scan Scan Speed Scan Depth In-depth Resolution Photographable Diameter of Pupil [Lateral] within 9mm [Vertical] within 9mm [Lateral] within mm [Vertical] within mm 12 128 ( 128 horizontal scan lines comprised of 12 A-scans ), mm 102 or 12 ( or 12 radial scan lines comprised of 102 A-scans ), mm 102 (102 A-scans per B-scan ), mm 12 128 ( 128 horizontal scan lines comprised of 12 A-scans ), mm 102 A-scans,.mm 2,000 A-scans per second 2.mm µm µm 2.mm or more Observation & Photography of Fundus Image / Fundus Tomogram Retinal Layers Identified Macula: ILM, IS/OS, RPE, BM OCT Reference Focus Vitreous and Choroid Fixation Adjustable internal matrix LCD and external fixation device Matrix LCD The display position can be changed and adjusted. The presenting method can be changed. ) Light Source / Power Source / Power Supply Light Source Power Source Power Supply Super Iuminescence diode(sld) Wavelength: 80nm Half Bandwidth: 0nm Output on cornea 0. mw Voltage: 100/110/120/220/20/20V Frequency: 0-0Hz 200VA (Max 00VA) Dimensions / Weight Dimensions Weight *Only for FA models **Display digital Red-free mm(w) mm(d) 00 0mm(H) kg(d OCT-2000) kg(d OCT-2000 FA) ***Without the diopter compensation ****More variable scan patterns available with a combination of different pixel and scan range. Please check with local Topcon dealer for PC specification. TOPCON MEDICAL SYSTEMS, INC. 111 Bauer Drive, Oakland, NJ 0, U.S.A. Phone:+1-201-99-100 Fax:+1-201-99-20 www.topconmedical.com TOPCON CANADA INC. 110 Provencher Avenue, Boisbriand, QC JG 1N1 CANADA Phone:+1-0-0-1 Fax:+1-0-0- www.topcon.ca TOPCON EUROPE MEDICAL B.V. Essebaan 11; 2908 LJ Capelle a/d IJssel; P.O.Box1; 2900 AC Capelle a/d IJssel; THE NETHERLANDS Phone:+1 -(0)10-80 Fax:+1 -(0)10-80 E-mail: medical@topcon.nl; www.topcon.eu ITALY OFFICE Viale dell' Industria 0; 200 Paderno Dugnano; (Milano), ITALY Phone:+9-02-9181 Fax:+9-02-91081091 E-mail: topconitaly@tiscali.it; www.topcon.it DANMARK OFFICE Praestemarksvej 2; 000 Roskilde, DANMARK Phone:+--200 Fax:+--2 E-mail: topcon@topcondanmark.dk www.topcondanmark.dk IRELAND OFFICE Unit 2, Blanchardstown; Corporate Park 2 Ballycoolin Dublin 1, IRELAND Phone:+-189900 Fax:+-182991 E-mail: medical@topcon.ie; www.topcon.ie TOPCON S.A.R.L. 89, rue de Paris 928 Clichy, FRANCE Phone:+-(0)1-1099 Fax:+-(0)1-9021 E-mail:topcon@topcon.fr; www.topcon.fr TOPCON DEUTSCHLAND G.m.b.H. Hanns-Martin-Schleyer Strasse 1; D-8 Willich, GERMANY Phone:+9-(0)21-880 Fax:+9-(0)21-881 E-mail:med@topcon.de; www.topcon.de TOPCON SCANDINAVIA A.B. Neongatan 2; P.O.Box 2; 11 Mölndal, SWEDEN Phone:+-(0)1-109200 Fax:+-(0)1-10929 E-mail:medical@topcon.se; www.topcon.se TOPCON ESPANA S.A. HEAD OFFICE Frederic Mompou Esc. A Bajos, 0890 Sant Just Desvern Barcelona, SPAIN Phone:+-9-0 Fax:+-9-92 E-mail: medica@topcon.es; www.topcon.es PORTUGAL OFFICE Rua da Forte,-A,L-0.22,290-02 Carnaxide,PORTUGAL Phone:+1-210-992 Fax:+1-210-988 www.topcon.pt TOPCON ( GREAT BRITAIN ) LTD. Topcon House,Kennet Side,Bone Lane,Newbury,Berkshire RG1 PX United Kingdom Phone:+-(0)1-1120 Fax:+-(0)1-110 E-mail:medical@topcon.co.uk; www.topcon.co.uk TOPCON POLSKA Sp. z. o. o. ul. Warszawska 2; 2-0 Siewierz, POLAND Phone:+8-(0)2-00 Fax:+8-(0)2-10 www.topcon-polska.pl TOPCON SINGAPORE MEDICAL PTE. LTD. 0 Alexandra Terrace, #08-2 The Comtech, Singapore 11802 Phone:+-8200 Fax:+-10 E-mail:medical_sales@topcon.comm.sg www.topcon.com.sg TOPCON INSTRUMENTS ( MALAYSIA ) SDN.BHD. No. D1, (Ground Floor), Jalan Excella 2, Off Jalan Ampang Putra, Taman Ampang Hilir, 100 Kuala Lumpur,MALAYSIA Phone:+0-(0)-2098 Fax:+0-(0)-209 TOPCON INSTRUMENTS ( THAILAND ) CO.,LTD. /12 Sinnsathorn Tower, th Floor,Krungthonburi Rd.,Klongtonsai, Klongsarn, Bangkok 1000,THAILAND Phone:+(0)2-0-112~ Fax:+-(0)2-0-118 TOPCON CORPORATION BEIJING OFFICE Block No.9, Kangding Street Beijing Economic-Technological Development Area, Beijing,1001,CHINA Phone:+8-(0)10-80-299 Fax:+8-(0)10-80-290 TOPCON CORPORATION SHANGHAI OFFICE 1L Huamin Empire Plaza, No.2, Yan-an Xi Road, Shanghai, 20000, CHINA Phone:+8-(0)21-28-22 Fax:+8-(0)21-2-01 TOPCON CORPORATION BEIRUT OFFICE P.O.Box 0-1002 Antelias,Beirut, LEBANON Phone:+91--22/22 Fax:+91--21119 TOPCON CORPORATION DUBAI OFFICE P.O.Box 290,Dubai Airport Free Zone L.I.U. J-12, Dubai, U.A.E Phone:+91--299-900 Fax:+91--299-901 2002-2011 Printed in Japan 2011 09-10 NP E000-1 S

State-of-the-Art Technology Increase Your Diagnostic Capability Topcon is always striving to provide the best possible products to meet the current and future needs of our customers. The advanced applications of Topcon D OCT will contribute to a better understanding of pathology and staging. FA OCT Color Changing Your View of Retina Red-free New diagnostic indicator could be built by the three-dimensional analysis Macular and disc volume rendering of the D data set provide excellent visualization of structural changes of the retina, vitreoretinal interface, convex elevation, swelling and thinning of layers, allowing clinicians to have quantitative interpretation of retina. Topcon D OCT System is the only Spectral Domain OCT system to incorporate a high resolution retinal camera and a user friendly color touch screen display in a compact, space saving design. The new D OCT-2000 FA model enables fluorescein angiography, color and red-free to be combined with SD OCT to change your view of the retina. Today more than 00 Topcon D OCT systems are used worldwide. Features Integrated, high resolution retinal camera for color, red-free and FA* fundus imaging Color touch screen display Auto disc centering, automatic capture functions and automatic extended depth imaging (Enhanced Choroidal Mode) ensure that anyone can take high quality images with minimal training FastMap software enables dynamic viewing of 2D, D and fundus images simultaneously Historic patient data from Stratus OCT can be easily imported, analyzed and viewed Seamless integration with Synergy Image Management System Comparison function and RNFL trend analysis function These dynamic comparison tools the monitoring of disease and treatment. Precise automatic registration assures examiners are analyzing the same scanned position under the same scanning condition everytime. High resolution, high density SD OCT imaging with IR tracking and automatic eye movement correction produce the highest quality image * available with D OCT 2000 FA model D OCT-2000 FA Optical Coherence Tpmography

Quantitative and Highly Reproducible Data with Extreme Ease of Use Easy Steps Ex) OCT photography 1 2 Register / Select patient Choose scanning pattern using color touch panel interface Capture Image will be automatically exported to PC Register or Select patient Color touch panel interface Color / OCT photography OCT Viewer Register or select patient from the OCT Viewer software. By inputting patient s axial length, corneal curvature, refractive diopter, Topcon Circle Scan Diameter Correction adjusts this circle to keep the consistent size diameter of.mm from the retina. Intuitive color touch panel allows easy selection of a scan pattern icon. Scan icons are easily personalized from the selection of over 00 different scan patterns. Up to 9 scan pattern icons can be displayed one screen. Auto functions ensure that anyone can take high quality images with minimal training. Color retinal photography: OCT photography: FA photography Auto focus / Auto shoot Auto focus / Auto Z&Z lock / Auto polarization Instant comparison of en face OCT projection image and color retinal image is available. To start FA photography. Touch at the same timing of dye injection. Timer starts to count. The photography mode can be easily switched between color and FA during capture without stopping the FA timer. Import Function Ex.D Disc Any fundus image (Color, FA, FAF, ICG, Red-free) can be imported and compared with OCT image. Ex.Import Function

Quantitative and Highly Reproducible Data with Extreme Ease of Use Topcon s advanced OCT technology significantly reduces eye movement artifacts and noise Easy Steps Ex) OCT photography 1 2 IR Tracking Function If the scanned area moves during capture Topcon s IR tracking technology removes suspect scans and automatically rescans missing area. Reference: IR Image Memorize the first scanning position 1 2 Removes Circle Disc Scan Auto disc lock & auto disc search function n provide more precise RNFL thickness results and improve visit to visit and inter/ intra operator reproducibility. Register / Select patient Choose scanning pattern using color touch panel interface If the scan position moves, it automatically removes the image Ex: Check! Additional scan was made Ex: makes it easier to automatically generates Register or Select patient Color touch panel interface D Disc Scan Register or select patient from the OCT Viewer software. By inputting patient s axial length, corneal curvature, refractive diopter, Topcon Circle Scan Diameter Correction adjusts this circle to keep the consistent size diameter of.mm from the retina. Intuitive color touch panel allows easy selection of a scan pattern icon. Scan icons are easily personalized from the selection of over 00 different scan patterns. Up to 9 scan pattern icons can be displayed one screen. Motion Correction / Compensation / Rescanning Function Microsaccades and other fixation issues are a major cause of motion artifacts. To minimize this influence, Motion Correction /Compensation / Rescanning Functions are automatically activated when capturing. Z Direction Motion artifact on Z direction due to microsaccades. X Direction Missed scan slices due to microsaccades. Motion artifact on X direction due to microsaccades. Reproducible Width Scan Width: mm Reproducible Width: mm *Available with disc D scan, mm Y Direction Compensate motion artifact on X direction. When D disc scanning, the red box (.0.0mm) makes it easier to automatically generatesautomatically generates RNFL thickness value extracted from a.mm peripapillary circle of data points centered on the optic disc. The green box shows the.0.0mm scanning area. Motion Correction Corrects the Z direction movement. Compensate motion artifact on Z direction. Automatically rescans the missing part of Y direction. Enhanced Choroidal Mode Enhanced choroidal mode allows the visualization of the choroid. Compensation Function Completed Tracks ocular and scans mm area, then compensates X direction movement. Rescanning Function Y direction movement can sometimes miss scanning area. In such case, the rescanning function automatically activates. Before After * Image

Topcon D OCT reports provide and unprecedented level of information to the clinician with OCT, color, and red-free images placed in one report. All the information you need is here. Enjoy enhanced communication with your patients and clinical care. Rich New Reports D Macula Report D Disc Report 1 1 2 8 2 1 Color Fundus Image Shadowgram 1 Color Fundus Image Red-free Fundus Image (Digital) The green box shows the OCT scanned area. The Surface photograph of the assembled OCT B-scans. The green circle indicates a.mm-diameter circle on Red-free image will more assist in detecting RNFL thinning. 2 blue arrow horizontal) and the pink arrow (vertical) on the color fundus image indicates the displayed tomogram. The displayed tomogram location can be changed. Red-free Fundus Image (Digital) ILM-RPE color map is overlaid. Horizontal & Vertical Tomogram Thickness Average/Center/Total thickness value appears. ILM-RPE Map RPE Surface Easy to observe overall and RPE macular condition. the optic disc. 2 Thickness Map (RNFL) Thicker regions are displayed as yellow, orange and red, whereas thinner regions are displayed as blue and green. Shadowgram Surface photograph of the assembled OCT B scans. Average Thickness Total/Superior/Inferior thickness value appears. RNFL Circular Tomogram Pseudo Color / Gray / Inverted Gray tomogram can be displayed. Pseudo Color / Gray / Inverted Gray tomogram can be displayed. RNFL Thickness Graph The RNFL thickness data can be divided into, 1, regions. ETDRS ETDRS (nine map sectors) thickness value* will be helpful in detecting subtle macular thickening or thinning in microns. * Macular volume can also be shown instead of thickness value. 8 Optic Disc Analysis & R/D Ratio Structure of an optic nerve head and its nerve head cupping can be understood by specific parameters.