Nicolet Almega XR. High Performance Micro and Macro Dispersive Raman Analysis Systems

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m o l e c u l a r s p e c t r o s c o p y Nicolet Almega XR High Performance Micro and Macro Dispersive Raman Analysis Systems Materials Research Identification/Verification Characterization Failure Analysis High-Throughput Screening Mapping in 3 Dimensions Part of Thermo Fisher Scientific

C UTTING-EDGE S OLUTIONS

Thermo Scientific Nicolet Almega XR Dispersive Raman Powerful, cutting-edge solutions for Raman High-performance Raman is coming of age as an analytical technique, and the Thermo Scientific Nicolet Almega XR system captures the full potential of this technique by offering a powerful research and development tool. Combining Raman performance with extremely flexible configurations and incredible ease of use, the system provides a wide range of solutions to analytical problems related to molecular structure. Wide-Ranging Applications and Sampling Flexibility Pharmaceuticals Semiconductor Devices Forensics Gems & Minerals Polymers Protective Coatings S AMPLING V ERSATILITY

P RODUCTIVE The innovative technology behind the Nicolet Almega XR dispersive Raman spectrometer lets you get the answers you need faster and with greater ease. Automated features engineered throughout the system mean your time is spent getting accurate results. Versatile sampling options designed to handle a wide variety of samples further increase productivity and lab efficiency. Automated Saves You Time and Makes Analysis Less Subjective Excitation laser and Rayleigh rejection filter switching Patented automatic laser alignment Automatic grating switching Automatic software configuration of instruments settings corresponds to laser and resolution selections Automating sampling experiments saves time and makes profiling larger areas easy Intuitive Operation and Short Learning Curve Simple software instrument controls Laser-safety interlocks for simple and safe operation Fast Real time feedback for manipulating instrument settings Switch between lasers as well as micro and macro sampling in seconds without any tools Autosampling options Complete Solutions Get All the Equipment and Support from One Source Everything integrated in one software and hardware package No laborious manual alignment or calibration routines Dependable Dependable and objective results with on board automated calibration Depend on safety with the full class 1 laser safe configuration Dependable operation with field proven design US. Patent 6,661,509, US Patent 7,233,870, other patents pending Advanced Sampling Options Maximize the power of the Nicolet Almega XR system with specialized sampling options for your specific analysis needs. Well-plate Autosampling Liquid Autosampling Powder Autosampling Capillary Tube Autosampling Remote Sampling

P OWERFUL The powerful set of tools provided by the Nicolet Almega XR system provides you with a wide selection of methods to interrogate your samples, and to generate the best possible data along with the software tools you will need to reveal all the information the data contains. The Nicolet Almega XR system gives you confidence that your lab is getting everything that the Raman technique has to offer. Powerful Software Toolkit Completely integrated package Total instrument control Data collection and advanced data manipulation tools Advanced library searching algorithms to give you better matches Extensive quantitative tools including multivariate and principle component-based methods for sophisticated quant Advanced chemical profiling option to view your results from multiple perspectives single wavenumber images peak ratio images quantitative analysis images Powerful Performance Simple custom report generation for displaying your results Data audit trails for regulation compliance Online help at every step to guide you Superior spatial resolution Broad spectral range Extremely low noise Superior fluorescence rejection Excellent sensitivity even with small samples Fast and accurate laser switching and alignment High throughput no fiber-coupled optics Powerful Hardware High-brightness lasers deliver more energy to your samples High-quality, visual viewing optics distinguish the small details of your sample TE-cooled, high-sensitivity, Si CCD for the best Raman detection Seamless switching between two excitation lasers Infinity-corrected optics Gratings optimized for each laser True confocal microscope optics for depth profiling Automatic alignment with all lasers so you always know where you are sampling without exposing your eyes to dangerous laser light Powerful Sampling Options Excellent small sample capabilities Nondestructive depth profiling Mapping in 3 dimensions with complete spectral information no sacrifices Mosaic mapping of sample areas larger than the field of view Polarization studies Automated white-light background correction High throughput auto-sampling Orientation independent crystalline studies using the depolarization kit Rapid sample interrogation with multiple excitation lasers Remote sampling

Versatile Configurations Open Architecture Fully Class-I Laser Safe Supports robotic sample delivery Comprehensive software tools Large selection of libraries Large selection of excitation lasers Large selection of visual viewing options transmission and reflection bright field and dark field polarized light Large selection of stages motorized stages heated and subambient sampling stages wafer stages Micro and macro sampling without compromises Autosampling well-plate autosampling options NMR tube and test tube autosampling Fully upgradeable to add capabilities as you need them and make sure you always have access to the technology you might need Every feature described is not included in every configuration. Many features are provided as options allowing you to configure a system to meet your specific requirements at the best possible price. Consult your sales representative for more information.

Laboratory Solutions Backed by Worldwide Service and Support The Nicolet Almega XR dispersive Raman system is backed up by the support staff of the largest analytical instrument company in the world, Thermo Fisher Scientific. Service and support is available almost everywhere in the world. We have more Raman-trained field service engineers and Raman-trained applications people to support you than any other company. Meeting all of your support needs is our highest priority. Comprehensive Support for Your Raman Needs: On-site visits from factory-trained field service engineers Technical phone support Internet-based technical support Performance maintenance programs Classroom and on-site training programs Contract method and application development programs In addition to these offices, Thermo Fisher Scientific maintains a network of representative organizations throughout the world. Africa +43 1 333 5034 127 analyze.emea@thermo.com Australia +61 2 8844 9500 analyze.au@thermo.com Austria +43 1 333 50340 analyze.at@thermo.com Belgium +32 2 482 30 30 analyze.be@thermo.com Canada +1 800 530 8447 analyze.ca@thermo.com China +86 10 5850 3588 analyze.cn@thermo.com Denmark +45 70 23 62 60 analyze.dk@thermo.com Europe-Other +43 1 333 5034 127 analyze.emea@thermo.com France +33 1 60 92 48 00 analyze.fr@thermo.com Germany +49 6103 408 1014 analyze.de@thermo.com India +91 22 6742 9434 analyze.in@thermo.com Italy +39 02 950 591 analyze.it@thermo.com Japan +81 45 453 9100 analyze.jp@thermo.com Latin America +1 608 276 5659 analyze.la@thermo.com Middle East +43 1 333 5034 127 analyze.emea@thermo.com Netherlands +31 76 587 98 88 analyze.nl@thermo.com South Africa +27 11 570 1840 analyze.sa@thermo.com Spain +34 914 845 965 analyze.es@thermo.com Sweden / Norway / Finland +46 8 556 468 00 analyze.se@thermo.com Switzerland +41 61 48784 00 analyze.ch@thermo.com UK +44 1442 233555 analyze.uk@thermo.com USA +1 800 532 4752 analyze.us@thermo.com www.thermo.com Thermo Electron Scientific Instruments LLC, Madison, WI USA is ISO Certified. If the Class I option is not selected then the system is a Class IIIb laser product. 2007 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific Inc. and its subsidiaries. Specifications, terms and pricing are subject to change. Not all products are available in all countries. Please consult your local sales representative for details. BR50446_E 12/07M