Relationships among formal mindfulness practice, mindfulness skills, worry, and quality of life

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Relationships among formal mindfulness practice, mindfulness skills, worry, and quality of life Across an acceptance-based behavior therapy for generalized anxiety disorder Lucas Morgan, Sarah Hayes-Skelton, Lizabeth Roemer (UMass Boston) & Susan Orsillo (Suffolk University) Presented by Lucas Morgan; University of Massachusetts Boston Anxiety Disorders Association of America, 2012, Arlington VA. 4.15.12

Disclosure Principle Investigators: Lizabeth Roemer, UMass Boston Susan Orsillo, Suffolk University Funding: NIMH grant MH074589

Mindfulness Nonjudgmental awareness of present-moment experience Awareness, attention to whatever arises Allowing, letting be, non-changing, opening to Increasingly applied in mindfulness- and acceptancebased clinical interventions: MBSR, MBCT, ACT, DBT, MBRP, etc. Mindfulness as practices & skills

Mindfulness: Skills Skills = the ability to engage mindfully in daily life Difficult to measure: self-report Five Facet Mindfulness Questionnaire (Baer et al. 2006) Describe: I m good at finding the words to describe my feelings Observe: I pay attention to physical experiences, such as the wind in my hair or the sun on my face Nonreact: I watch my feelings without getting carried away by them Nonjudge: I tell myself I shouldn t be thinking the way I m thinking Act with Awareness: it seems I m running on automatic with little awareness of what I m doing

Mindfulness: Skills Higher levels of and increases in skills (FFMQ, MAAS, FMI, KMS, etc.) related to important clinical health constructs Psychological symptoms, perceived stress, psychological well-being, selfcompassion, anxiety, depression, thought suppression, emotion regulation difficulties, experiential avoidance (Baer et al., 2006; Carmody & Baer, 2008) Learned by participants with diverse clinical presenting problems: how are skills learned?

Mindfulness: Practice If mindfulness is a skill, it can be learned, and skills will improve with practice Formal: setting aside time sitting, walking, body-scan, mindful yoga Informal: purposeful application to daily life activities dishes, driving, taking the bus, bathing Mixed relationship between amount of formal between-session practice and outcomes (Vettese et al. 2009): Meta-analysis; MBSR studies; Cross-sectional: 13 of 24 studies found positive relationships

Acceptance Based Behavior Therapy Individual therapy; 16 sessions GAD (uncontrollable worry, difficulty concentrating, irritability, tension, sleep disturbance, fatigue, causes distress or impairment) Core ABBT components Teach mindfulness skills (flexibly) Increase awareness, acceptance, decentering Decrease experiential avoidance Increase valued action

General Question Does practicing formal mindfulness early in treatment lead to increases in mindfulness skills, which then predict clinical improvements for GAD? Longitudinal design: temporal precedence Practice skills, outcomes

Hypotheses 1. Higher frequency of formal mindfulness practice across the first four sessions would predict greater increases in mindfulness skills across treatment 2. Higher frequency of formal mindfulness practice across the first four sessions of therapy would predict greater improvements in worry and quality of life across treatment.

Hypotheses 3. Larger trajectories of change in mindfulness skills would predict greater improvements in worry and quality of life across treatments 4. Increases in the rate of change in mindfulness skills would mediate the relationship between frequency of mindfulness practice across the first four sessions of treatment and changes in symptom variables across treatment

Mediation Model + Temporal Precedence 1 Skills change 3 Early Formal Practice 2 Outcome change

Measures Frequency of formal practice across sessions 2-4 Weekly in session, client report Current sample: mean 18.5 (SD=8.9) total practices or about 6.2 per week Pre, Mid-4, 8, 12, Post Mindfulness Skills: FFMQ Baer et al. (2006) Worry: PSWQ-PW Stober & Bittencourt (1998) Quality of Life: QOLI Frisch, Cornwell, Villanueva, & Retzlaff (1992) 16 life domains: Importance x Satisfaction

Sample 33 people with GAD (principal diagnosis) 77% White; 66% female; 94% heterosexual; mean age = 34; mean # of additional diagnoses = 1.07 (Most common: SAD, depressive disorders, OCD)

Latent Growth Curve Modeling SEM method for calculating estimates of longitudinal change Takes into account individual change variation Mplus software Computes missing data through maximum likelihood replacement

Results: Hypothesis 1 & 2 Step 1: Unconditional Models Slope of change between time points (m4,m8,m12,post) Estimate Standard Error z-value FFMQ (n=33) 6.90 0.71 9.68*** QOLI (n=33) 0.41 0.08 5.47*** PSWQ-PW (n=32) -3.96 0.79-4.66*** Significant improvement between time points across treatment (m4 to Post) Unstandardized: e.g. Skills increased 6.9pts on FFMQ every 4 sessions

Results: Hypothesis 1 & 2 Step 2: Conditional Models: Practice added as time-invariant predictor of slopes Beta z-value p-value FFMQ (n=31) 0.33 0.70 0.48 QOLI (n=31) -0.12-0.28 0.78 PSWQ-PW (n=30) -0.31-0.92 0.36 Early frequency of practice did not predict magnitude of change in skills, quality of life, or worry Hypotheses 1 and 2 were unsupported

Results: Hypothesis 3 (does skill change predict outcome change?) Residual Gains: regression of m4 on Post scores Gives change score above and beyond variation in Post scores predicted by m4 scores Correlations between residual gains of FFMQ and outcomes Pearson s r p-value QOLI (n=30) 0.57.001 PSWQ-PW (n=21) -0.54.01 Hypothesis 4 was unable to be tested

Discussion Frequency of early formal mindfulness practice did not predict observed improvements in mindfulness skills, worry, and QOLI Mindfulness skill increases related to improvements in worry and quality of life mindfulness skill gain is clinically beneficial for people with GAD

Why not formal practice? Low power: Type II error? Did not measure duration (minutes) of practice No measure of quality of practice Meditation as experiential avoidance? ABBT: many avenues of learning mindfulness informal practice, psychoeducation, metaphors, therapist modeling, valued action Cultural/worldview congruence, prior experience,, interactions?

Limitations & Future Directions Imperfect measurement of practice, skills Did not measure informal practice No measure of quality of practice Mindfulness with culturally, racially, and socioeconomically diverse populations Mechanisms of mindfulness; specific facets of mindfulness skills How to optimize mindfulness skill acquisition?

Conclusion Mindfulness skills may be an important target in treatment for people with GAD Related to decreased worry, increased quality of life Not directly related to frequency of early formal practice Indicates multiple (possibly interacting) ways of learning mindfulness skills Provide flexibility for clients backgrounds, life contexts, and preferences

References Baer, R. A., Smith, G. T., Hopkins, J., Krietemeyer, J., & Toney, L. (2006). Using self-report assessment methods to explore facets of mindfulness. Assessment, 13, 27-45. doi: 10.1177/1073191105283504 Carmody, J., & Baer, R. A. (2008). Relationships between mindfulness practice and levels of mindfulness, medical and psychological symptoms and well-being in a mindfulness-based stress reduction program. Journal of Behavioral Medicine 31, 23-33. doi: 10.1007/s10865-007- 9130-7 Frisch, M. B., Cornwell, J., Villanueva, M., Retzlaff, P.J. (1992). Clinical validation of the Quality of Life Inventory: a measure of life satisfaction of use in treatment planning and outcome assessment. Psychological Assessment, 4, 92-101. doi: 10.1037/1040-3590.4.1.92 Stober, J., & Bittencourt, J. (1998). Weekly assessment of worry: An adaptation of the Penn State Worry Questionnarire for monitoring changes during treatment. Behavior Research and Therapy 36, 645-656. doi: 10.1016/S0005-7967(98)00031-X Vettese, L. C., Toneatto, T., Stea, J. N., Nguyen, L., Wang, J. J. (2009). Do mindfulness meditation participants do their homework? And does it make a difference? Review of the empirical evidence. Journal of Cognitive Psychotherapy: An International Quarterly, 23, 198-225. doi: 10.1891/0889-8391.23.3.198