RETOUR D EXPÉRIENCE SUR LE MONTAGE DE PROJET INFRA-IA STARTING COMMUNITIES

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RETOUR D EXPÉRIENCE SUR LE MONTAGE DE PROJET INFRA-IA STARTING COMMUNITIES Projet SmartCow, J.Levin (INRA) Projet EU_FT-ICR_MSC, Rolando (CNRS) Journée nationale d information 17/10/2017, Paris (MESRI)

SmartCow Retour d expérience Jonathan Levin Infrastructures de Recherche Infoday national, Paris, 17/10/2017

SmartCow An integrated infrastructure for increased research capability and innovation in the European cattle sector 2018-2022 Coordinator René Baumont Topic INFRAIA-02-2017 (Starting Communities) Provisional starting date : 1st February 2018 17/10/17 Infrastructures de Recherche Infoday national, Paris.03

17/10/17 Infrastructures de Recherche Infoday national, Paris.04

Un projet d infrastructure n'est pas un projet qui vise à résoudre une question scientifique 17/10/17 Infrastructures de Recherche Infoday national, Paris.05

Three types of activities in INFRAIA projects NA: Networking activities to foster a culture of co-operation between research infrastructures, scientific communities, industries and other stakeholders as appropriate, and to help develop a more efficient and attractive European Research Area JRA: Joint Research Activities to improve, in quality and/or quantity, the integrated services provided at European level by the infrastructures TNA: Transnational Access (or VA: Virtual Access) to support scientific communities in their access to the identified key research infrastructures 17/10/17 Infrastructures de Recherche Infoday national, Paris.06

Overall organisation of the SmartCow project. 17/10/17 Infrastructures de Recherche Infoday national, Paris.07

Networking activities An interactive map of national and regional cattle RIs across Europe (WP1); Inventory of cattle databases and samples banks (WP1) A TNA program that places SmartCow RIs at the centre of addressing key European research challenges in a coordinated way (WP2) A cloud-based data platform to gather and share research data on cattle (WP3) A book of methods to harmonise protocols and define common guidelines for research and routine data recordings on cattle (WP3) An improved trait ontology (ATOL and EOL) to define and disseminate a common language in cattle research (WP3) Effective and sustainable dissemination and knowledge transfer to stakeholders and training of a new generation of scientists, students and technicians to foster innovation (WP4). 17/10/17 Infrastructures de Recherche Infoday national, Paris.08

Prends le temps de bien travailler le TNA et ses coûts d accès SmartCoW TNA: Access to 10 RIs 20 installations Around 2500 dairy and 1000 beef cows Diversity of breeds and of environmental conditions High quality measurements (feed efficiency, gas emissions, digestion, metabolism ) Expertise in animal science, cattle husbandry and research methodologies TNA 1.5 M : Cover the cost of 33 experiments 10000 cow.week Two types of comprehensive experiments 1. Experiments on animals in production focusing on animal performances and trade-offs between functions ; 2. Experiments investigating underlying digestive and metabolic processes on limited amount of animals. 17/10/17 Infrastructures de Recherche Infoday national, Paris.09

Proposer des JRAs qui améliorent les services de recherche proposés par les infrastructures Par exemple amélioration des méthodologies. SmartCow Joint research activities Evaluation and refinement the state of the art in vivo methods in the field of nutrient efficiency and emissions of cattle in order to improve their accuracy and reduce the number of experimental animals in cattle research (WP5). Development, where possible, of proxies (biomarquers from NIR and MIR technology) and non-invasive methods to increase phenotyping capabilities and reduce constraints on experimental animals (WP6). Development of a multivariate approach from data coming from sensors in SmartCow infrastructures to phenotype health, welfare and feed efficiency in cattle (WP7) Implementation of the 3 R (Replace, Reduce, Refine) principles 17/10/17 Infrastructures de Recherche Infoday national, Paris.010

Veiller à une bonne répartition des ressources Budget SmartCow 5M 17/10/17 Infrastructures de Recherche Infoday national, Paris.011

Governance General Assembly Scientific Advisory Board Coordination assistance team Coordinator Access management team Executive Committee Stakeholder Platform JRA WPs NA WPs TNA WPs Selection Panel Ethical Board 17/10/17 Infrastructures de Recherche Infoday national, Paris.012

C est un appel blanc Evaluation Votre projet doit être compréhensible pour tous. Il peut être évalué par des «experts» qui ne connaissent pas votre domaine 17/10/17 Infrastructures de Recherche Infoday national, Paris.013

Merci 17/10/17 Infrastructures de Recherche Infoday national, Paris.014

EU_FT-ICR_MS European Network of Fourier-Transform Ion-Cyclotron- Resonance Mass Spectrometry Centers An INFRA for Starting Communities network Christian Rolando Christian.Rolando@univ-lille1.fr Infrastructures de Recherche Journée nationale d information, mardi 17 octobre

Summary 1 2 3 4 5 6 7 8 Why an FT-ICR MS network? Geographical repartition and financial model The site specificities and the different workpackages The two steps and our evaluation Funding the preparatory phase: ANR MRESI The project team Look to available documents! Think to the future! Page 2 Infrastructures de Recherche Infoday national, Paris, 17/10/2017

Why an FT-ICR Mass Spectrometers network? 15 Tesla FT-ICR MS at the Czech Academy of Science, Institute of Microbiology (Prague) funded in part with EU ERDF funds (highest commercial magnetic field). The most resolving mass spectrometer ( 10 versus the best other MS) Ubiquitous use in different scientific field Cost between 1.5 and 3 million euros Page 3 But requires a skilled team Infrastructures de Recherche Infoday national, Paris, 17/10/2017

Geographical repartition and financial model Ten academic centers from 8 European countries and Russia 2 SMEs (software development and project management) 1 instrumentation company Page 4 A financial model with almost equivalent funding for all academic partners

The site specificities and the different workpackages And the very important WP Open Data and e-infrastructure Page 5 Infrastructures de Recherche Infoday national, Paris, 17/10/2017

The two steps and our evaluation INFRAIA-02-2017: Integrating Activities for Starting Communities 30 Mar 2016 (First stage): 20 pages only Excellence and Impact 29 Mar 2017 (Second stage): 100 pages Excellence, Impact and dissemination + the description of the partners (50 pages, not limited) The template for the Excellence part of the Second stage is not well adapted to an INFRA call and induces a recursive writing. Excellence 1.1 Objectives Describe the specific objectives for the project, which should be clear, measurable, realistic and achievable within the duration of the project. Objectives should be consistent with the expected exploitation and impact of the project (see section 2). 1.2 Relation to the work programme Page 6 Indicate the work programme topic to which your proposal relates, and explain how your proposal addresses the specific challenge and scope of that topic, as set out in the work programme.

The two steps and our evaluation The main objectives of the project are to develop an European state of the art network enabling high resolution FT ICR mass spectrometry providing superior analyses and offering transnational access (TNA). The objectives are clearly demonstrated, well explained and justified. The procedure in which the partners with FT ICR-MS facilities will join forces to offer the most up to date TNA to the European scientific community is convincingly shown. The TNA and the JRA will be completed by Network Activities, which are well described and will be performed at three different levels dedicated to different groups. The proposal addresses multidisciplinary aspects. The coordination with a US infrastructure is a strong point as well. Additionally, long-term sustainability is also taken into account. The focus on the quality of the measurement techniques, exchange of expertise as well as establishing high quality standards for the community are strong and convincingly described in Page the 7 proposal. Infrastructures de Recherche Infoday national, Paris, 17/10/2017

The two steps and our evaluation The community will be provided with simplified, harmonised access to the state-of-the-art technique, and count on the support of experts. Research organizations and industry will both benefit from the network. The measures to improve data management as well as training activities are well described in the proposal. The involvement of industrial partners who will use the facility in the project and their representation in the Stakeholder Committee will help to enhance dissemination of the results. However, the effective involvement of manufactures is not fully described. The dissemination and exploitation plans are well presented and include measurable indicators. The communication plan is appropriate. The work plan is well described. The management plan is well presented, and decisionmaking structures are adequate to the objectives and WPs. The allocation of resources is appropriate and well balanced. The participants are quite complementary, with recognized scientific authorities among them. However, the risk management is not described in detail. The innovation and exploitation plans are too generic and lack in details. Page 8 Infrastructures de Recherche Infoday national, Paris, 17/10/2017

Funding the preparatory phase: ANR MRSEI Montage de réseaux scientifiques européens ou internationaux (MRSEI) Construction de l Espace européen de la recherche (EER) et attractivité internationale de la France Submission on January 2016, acceptation in May 2016 Funding (30 k ) of: The European project consulting company (10 k ) The meetings of the consortium during the preparatory phase in an easily accessed place The travels of the PI for the set-up of the project Web site Page 9

The project team French FT-ICR network, FR CNRS 3624 National Research Infrastructure http://www.fticr.org/ Pr Guillaume VAN DER REST European project s engineer In charge of budget and especially TNA Maude PERIER-CAMBY European consulting company Writing assistance and supervision WP dissemination and management Céline BLANCHON & Hervé MUGUERA Page 10 Infrastructures de Recherche Infoday national, Paris, 17/10/2017

Look to available documents! Guidelines for implementing TransNational Access www.desca-2020.eu/ DESCA 2020 model consortium agreement https://portal.meril.eu/meril/ The MERIL (Mapping of the European Research Infrastructure Landscape) portal provides access to a database that stores information about openly accessible research infrastructures (RIs) in Europe, across all scientific domains, including the social sciences and humanities. https://ec.europa.eu/jrc/en/research-facility/open-access/framework Access of users to JRC research infrastructures will be regulated by the "Framework of Access to Joint Research Centre physical Research Infrastructures" ('Framework') drafted by the JRC and based on European Charter for Access to Research Infrastructures. https://ec.europa.eu/research/infrastructures/pdf/2016_charterforaccessto-ris.pdf European Charter for Access to Research Infrastructures: Principles and Guidelines Page 11 for Access and Related Services Infrastructures de Recherche Infoday national, Paris, 17/10/2017

Think to the future! The message from Gaëlle DECROIX and Jean-Pierre CAMINADE An INFRA starting communities should be seen as a starting point and not as Page an 12 end point Infrastructures de Recherche Infoday national, Paris, 17/10/2017

The EU_FT-ICR_MS at a glance Start: 1 st January 2018 Website Page 13 (project submission): www.eu-fticr.eu Infrastructures de Recherche Infoday national, Paris, 17/10/2017