Research Infrastructures from FP7 to Horizon 2020

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Research Infrastructures from FP7 to Horizon 2020 Brigitte Sambain DG Research & Innovation Research Infrastructures Unit B3 Research and Innovation Funding opportunities under R&I and Mobility schemes in the Fields of Pharmacuetical and Medical Biotechnologies, ENEA, Brussels, 20 June 2012

Research Infrastructures for the Life Sciences Imaging facilities Biological Resource Centres Genomics and Proteomics facilities Bioinformatics resources Medical research facilities Food and agriculture research facilities

Why a EU approach? To open access to the research infrastructures existing in the individual Member State to all European researchers To avoid duplication of effort and to coordinate and rationalise the use of these research infrastructures To trigger the exchange of best practice, develop interoperability of facilities and resources, develop the training of the next generation of researchers To connect national research communities and increase the overall quality of the research and innovation To help pooling resources so that the Union can also acquire and operate research infrastructures at world level

ESFRI European Strategy Forum on Research Infrastructures Set up by the EU Council of Research Ministers in 2002 Brings together representatives of Ministers of the 27 Member States, 10 Associated States, and of the European Commission Supports a coherent and strategy-led approach to policy making on Research Infrastructures Mandate to develop a Roadmap (2006) and its updates (2008, 2010) Contains 48 projects Requiring major financial investment (~20 b ) and long term commitment for operation (~2 b /year)

Imaging facilities EUROBIOIMAGING Imaging facilities Biological Resource Centres BBMRI - Biobanks and Biomolecular Resources EMBRC - Marine biology resources EU-OPENSCREEN - Chemical libraries INFRAFRONTIER - Mouse archives and clinics MIRRI Microbial resources Genomics and proteomics facilities INSTRUCT - Structural biology facilities Bioinformatics resources ELIXIR Data repositories ISBE Infrastructure for systems biology Medical research facilities EATRIS - Translational research facilities ECRIN - Clinical trial plateform ERINHA - High-security labs

ERIC: European Research Infrastructure Consortium A new legal framework, at EU level, to facilitate the joint establishment and operation of Research Infrastructures of European interest among several countries A legal personality recognised in all EU Member States Current status for Life Sciences: Applications submitted: ECRIN, EATRIS Other applications under preparation: BBRMI

FP7 Research Infrastructures (1.7 B ) Preparatory phases of ESFRI projects (210 M ) Support to the construction of ESFRI projects (90 M ) Integrating Activity networks (670 M ) supporting in particular access e-infrastructure projects (410 M ) Design studies for new research infrastructures (45 M ) Policy measures (75 M ) Contribution to RSFF (200 M )

FP7 projects for Life Sciences (42 projects, ~ 231 M of EU funding) Genomics and proteomics research facilities INSTRUCT, Bio-NMR, East-NMR, Pcube, BioStruct-X, ESGI, Prime-XS, enmr, WeNMR, ERA-Instruments Medical research facilities ERINHA, EATRIS, ECRIN, ECRIN-IA, Transvac, ULICE Imaging facilities Euro-BioImaging, neugrid, outgrid, DECIDE, N4U Biological Resource Centres BBMRI, EMBRC, EU-Openscreen, INFRAFRONTIER EMMAservices, EMBaRC, EVA, Infravec, EUPRIMnet-II, Assemble, InfraComp Food and agriculture research facilities NADIR, AQUAEXCEL, EPPN, Trees4Future, transplant, ERIN Legend: Red: Preparatory Phase project Green: e-infrastructure project Bioinformatics resources Blue: Integrating Activity project Black: Other ELIXIR, SLING, IMPACT, BioMedBridges

Thematic coverage Broad thematic coverage, corresponding to priorities as expressed in several national roadmaps for infrastructures Still, several categories of infrastructures not covered by FP7 projects Plant genetic resources, experimental farms, food analysis facilities, transcriptomics facilities, metabolomics facilities, GMP facilities for therapy, etc. All funded FP7 infrastructures for Life Sciences, including e- infrastructures, do contribute to addressing societal challenges Health, demographic change and wellbeing Food security, sustainable agriculture, marine and maritime research, and the bio-economy

GERD (B, 2009) >25 10-25 5-10 <5 0 0 10 70 232 115 40 263 00 272 8 1 30 71 Access to Life Sciences RIs 4 0 30 2 0 10 40 5 0 2 0 00 00 00 FP7: 169 RIs 121 00 30 11 0 20 0 0 Third countries: 10 0 0 21 00 FP6: 16 RIs

Overall impact The Framework Programme offered an opportunity for infrastructure communities to get structured 2/3 of the infrastructures identified by ESFRI were previously supported by FP projects Users under FP7: ~13 000 estimated hands-on users, >100 000 web-based users

Impact Examples from projects Excellent and innovative research based on access funding Drought resistance: Structure of the plant receptor for abscisic acid published in 2009 in Nature 462:665-668 (PCUBE) Training of users More than 500 users across Europe trained to bioinformatics services (SLING)

Impact Examples from projects Development of unified services Distributed EMMA repository with 2200 mouse strains, and one single entry point (EMMAservices) Development of virtual services A virtual laboratory where to analyze image databases on persons with neurodegenerative diseases (N4U) Sharing best practices Handbook, DVD and more than 30 courses for personnel working with non-human primates (EUPRIM-Net)

Impact Examples from projects Development of common standards and interoperability Towards a unique global infrastructure (EU, USA,CA) for neuro-images (outgrid) Development of innovative prototypes and methods A tracking system prototype for 4D ion radiotherapy (ULICE)

Conclusions from FP7 A leading role for supporting, structuring and integrating European research infrastructures, and thus for building the ERA A trigger for longer-term cooperation A broad scientific coverage A broad geographic coverage An increased and facilitated access Some future challenges Address thematic gaps Address properly the data challenge Reinforce cooperation with other actions to better respond to grand challenges, e.g. FET Flagships and JPIs Develop international cooperation Better measure and communicate the impact of the programme

Horizon 2020 Excellent science (24 598 M, constant 2011 prices) European Research Council (13 268 M ) Future and Emerging Technologies (3 100 M ) Marie Curie actions (5 752 M ) European Research infrastructures (including e-infrastructures) (2 478 M ) Societal challenges (31 743 M ) Health, demographic change and wellbeing (8 028 M ) Food security, sustainable agriculture, marine - maritime research, bio-economy (4 152 M ) Secure, clean and efficient energy (5 782 M ) Smart, green, integrated transport (6 802 M ) Climate action, resource efficiency, raw materials (3 160 M ) Inclusive, innovative and secure societies (3 819 M ) EIT (1 364 B + 1 461 B ) Industrial leadership (17 938 M ) Leadership in enabling and industrial technologies (ICT, space, nanotechnologies, advanced materials and advanced manufacturing and processing, biotechnology) (13 781 M ) Access to risk finance (3 538 M ) Innovation in SMEs (619 M ) JRC (non-nuclear: 1 961 M )

Research Infrastructures 4.1. Developing the European RIs for 2020 and beyond 4.1.1 Developing new world-class RIs 4.1.2 Integrating and opening national RIs of pan-european interest Main actions 4.1.3 Development, deployment and operation of ICT based e-infrastructures 4.2. Fostering the innovation potential of RIs & their human capital Specific actions 4.3. Reinforcing European RI policy and international cooperation Policy actions

From FP7 to Horizon 2020 An increased budget, from around 1.7 billion (FP7) to 2.5 billion (Horizon 2020 2011 constant prices) New activities to support the implementation and operation of world-class infrastructures such as ESFRI infrastructures Continuation of the successful FP7 Integrating Activities Reinforcement of the support to e-infrastructures New objective of better exploiting the innovation potential and human capital of infrastructures

Next steps for Horizon 2020 Ongoing Ongoing Mid 2012 Mid 2013 Parliament and Council negotiations on the basis of the Commission proposals Parliament and Council negotiations on EU budget 2014-2020 (including overall budget for Horizon 2020) Final calls under 7th Framework Programme for research to bridge gap towards Horizon 2020 Adoption of legislative acts by Parliament and Council on Horizon 2020 1/1/2014 Horizon 2020 starts, launch of first calls

Structural Funds Developing synergies between the Structural funds and Horizon 2020 is a priority of the European Commission More specific reference to research infrastructures "of European interest" is made in the European Commission proposal for the European Regional Development Fund Also, Horizon 2020 foresees support to activities dedicated to developing cooperation between research infrastructures and other Union policies, such as Cohesion, through relevant studies and communication tasks

For further information Europe 2020 http://ec.europa.eu/eu2020 Innovation Union http://ec.europa.eu/research/innovation-union Horizon 2020 http://ec.europa.eu/research/horizon2020 FP7 http://cordis.europa.eu/fp7/ EC Research Infrastructures and ESFRI http://ec.europa.eu/research/infrastructures EC Regional Policy http://ec.europa.eu/regional_policy