Apprendre des succès et des échecs de l innovation

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Chaire d innovation technologique Liliane Bettencourt Apprendre des succès et des échecs de l innovation Elias Zerhouni 22 février 2011 1

Converging Principles Separate funding from operating or executing science and innovation programs Keep accountability by independent and credible systems of evaluation Allow full autonomy with least administrative burden but for periods of time with full review Focus resources on scientists during «creative» period bt provide alternate career pathways Avoid rigid employment system Encourage interactions with educational and business sectors

Modeles institutionels des sciences et de l innovation MIT 1861 founder and first president, William Barton Rogers, designed MIT as a powerful mechanism for discovery and innovation. By teaching science and engineering as hands-on activities, Rogers helped gave the world a compelling model of an innovation machine. Allowed professors to work with industry

L impact du MIT 1930 s Stanford University recruited Fred Terman from MIT. He replicated the MIT model He helped establish Fairchild industries and Hewlett-Packard by young assistant professors which seeded the creation of the Silicon Valley Cluster Started the tradition of «Garage enterprises»

L impact du MIT World War II saw the beginning of academia- Governement partnerships led by presidents of major universities including Carl Compton and Vannevar Bush from MIT who led the creation of NSF and NIH Dr Compton convinces Boston bankers to create the first ever venture capital fund One of the first start up is Digital Eqipment Corporation seeding the technology cluster in Boston and leading to the development of venture capital firms for early stage ventures 61 Nobel Laureates

L institut Pasteur Created by Pasteur with philanthropic donations First institute to promote the concept of research and education directly linked to innovation on an international basis. With Merieux creates the first base of the Vaccine industry 10 Nobel Prizes

Johns Hopkins University First US graduate research university Created through a gift of Johns Hopkins a merchant in Baltimore on the concept of the research University inspired by the German model of intertwined Education; research and its applications First dean of the Medical School Henry Welch recruits worldwide leading scholars Osler, Kelly, Flexner They create the HOPKINS MODEL of side by side Research, Practice and Education which became the US model of medical research and training- 35 Nobel Prizes trained at Hopkins Inspired the creation of the Rockefeller University including the Peking Union Medical College

Essential characteristics A passionate visionary founder or group of founders Passion for excellence at the junction of research, education and practice Unconventional approach at the time Creation of an ecosystem of innovation through social influencing Highly selective institutions recruiting the best and brightest at all levels Providing high degree of freedom and autonomy They train the next generation of leaders

3,114 New Technologies Brought to Market By 185 US Research Institutions (1998-2004) Funding to Develop Technologies Provided by Both US Government and Private Industry 4,543 New Companies Formed Around Technologies from US Research Institutions (1980-2004) 2,671 Companies Still in Operation as of 12/2004 Alaska Data: Assoc of University Technology Managers (AUTM) Survey 2004

The concept of innovation cluster Innovation occurs in geographic clusters Chemical cluster in Lyon and Basel Device alley in Minnesota Automobile cluster Detroit, Turin Wine clusters France, California A concentration of all the critical elements in one region to accomplish the highly complex integration needed for breakthrough innovations A supportive financial, legal and cultural environment A set of core institutions of research that enrich the mix by attracting and selecting the best students and faculty