Philips Key advantages including improved image quality and with AC offers improved image quality, interpretative certainty, diagnostic Alternatively, simplify patient care by exposing patients to reduced radiation
This proven technology uses a patented matched dual- uniformity. with AC allows for the use of an attenuation corrections in addition to resolution recovery. Incorporating imaging physics into allows reconstructions with fewer counts (via reduced time or reduced dose). has been validated in a multi- Interpretive certainty data reconstructed with enables equivalent interpretive certainty compared with full-count data reconstructed 60 p=0.181 40 20 0 Equivocal Better image quality data reconstructed with allows improvements in image quality beyond that provided by full-count data reconstructed using. 10 5 3 2 1 p<0.001 10 5 3 2 1 Excellent/Good Fair/Poor Excellent/Good Fair/Poor 2
with AC improves both interpretive certainty and diagnostic accuracy. Interpretive certainty Full count 60 40 20 0 Equivocal with AC Half count 60 40 20 0 Equivocal with AC 3
Diagnostic accuracy Full count 10 5 3 2 1 Half count p=0.07 p=0.015 p=0.007 10 p=0.469 p=0.001 p=<0.001 70 5 3 2 1 Sensitivity Specificity Normalcy Sensitivity Specificity Normalcy with AC with AC imaging with improves accuracy. Reducing patient imaging time can help achieve higher throughput. Stress-only protocols are enabled by combining AC by reducing the need for rest imaging in patients with stress studies. Do more with less because half-count imaging and stress-only protocols allow you to maintain diagnostic accuracy while lowering the effect of the rising costs of radiopharmaceuticals on your department's budget. 10 5 3 2 1 p=0.442 p=0.113 p=0.079 Sensitivity Specificity Normalcy 4
Focus on patients helps you simplify patient care by allowing you to inject half the dose and imaging at full time, exposing patients to reduced radiation doses while maintaining accuracy. Alternatively, shorter scan times using full injected dose may improve patient comfort and convenience. with AC also may eliminate the need for rest imaging, helping to improve the patient experience. Measured collimator-depth resolution properties and radial distance Filtering method to preserve resolution and minimize noise Modeled for multiple radionucleotides* Flexible imaging times Half-time cardiac (for both perfusion and function), Tc-99m and TI-201 Flexible injected dose Integrated into processing workstation Compatible with correction for patient motion SPECT procedures Attenuation correction with CT-based attenuation maps Attenuation correction with Vantage-based attenuation maps Model-based scatter correction (with available attenuation map) 5
References for improved image quality. Nuclear Science Symposium Record, 2006. IEEE Volume 4, Issue Oct 29, 2006. pp 2285-2287. 2 Venero CV, Ahlberg AW, Bateman TM, et al. Enhancement of nuclear cardiac with depth-dependent collimator resolution applied to full and half-time acquisitions. Presented at ACC 2008, Chicago, IL, USA. 3 Bateman TM, Heller GV, McGhie AI, et al. Application of simultaneous Gd-153 line source attenuation correction to half-time stress-only SPECT acquisitions: a multi-center clinical evaluation. Presented at ACC 2008, Chicago, IL, USA. 4 Bateman TM, Heller GV, McGhie AI, et al. Multicenter investigation comparing a rest-stress Tc-99m SPECT imaging. Presented at ASNC 2008, Boston, MA, USA. 5 Venero CV, Ahlberg AW, Bateman TM, et al. Enhancing nuclear cardiac laboratory dependent collimator resolution applied to full- and half-time acquisitions with simultaneously acquired Gd-153 line source attenuation correction. Presented at ASNC 2008, Boston, MA, USA. 6 Cullom SJ, Saha K, Case JA, et al. An optimized iterative reconstruction and myocardial perfusion SPECT. Presented at ASNC 2008, Boston, MA, USA. 7 Venero CV, Heller GV, Bateman TM, et. al. A multicenter evaluation of a new post-processing method with depth-dependent collimator resolution applied to full and half-time acquisitions without and with simultaneously acquired attenuation. Journal of Nuclear Cardiology, in press, 2009. 8 Bateman TM, Heller GV, McGhie AI. Multicenter investigation comparing a highly rest-stress Tc-99m SPECT imaging. Journal of Nuclear Cardiology, in press, 2009. 2009 Koninklijke Philips Electronics N.V. All rights are reserved. or to discontinue any product at any time without notice or obligation and will not be liable for any consequences resulting from the use of this publication. Philips Healthcare is part of Royal Philips Electronics healthcare@philips.com fax: +31 40 27 64 887 Printed in The Netherlands 4522 962 52821 * JUL 2009 Philips Healthcare Global Information Center P.O. Box 1286 5602 BG Eindhoven The Netherlands