REPORT ON THE RESEARCH UNIT: UNDER THE SUPERVISION OF THE FOLLOWING INSTITUTIONS AND RESEARCH BODIES:

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Research evaluation REPORT ON THE RESEARCH UNIT: Laboratoire Physico-Chimie Curie PCC UNDER THE SUPERVISION OF THE FOLLOWING INSTITUTIONS AND RESEARCH BODIES: Université Pierre et Marie Curie Institut Curie Centre National de la Recherche Scientifique - CNRS EVALUATION CAMPAIGN 2017-2018 GROUP D Report published on April, 06 2018

In the name of Hcéres 1 : In the name of the expert committee 2 : Michel Cosnard, President Pierre-François Lenne, Chairman of the committee Under the decree No.2014-1365 dated 14 November 2014, 1 The president of HCERES "countersigns the evaluation reports set up by the expert committees and signed by their chairman." (Article 8, paragraph 5); 2 The evaluation reports "are signed by the chairman of the expert committee". (Article 11, paragraph 2).

Laboratoire Physico-Chimie Curie, PCC, U PARIS 6, INST CURIE, CNRS, Mr Maxime DAHAN This report is the sole result of the unit s evaluation by the expert committee, the composition of which is specified below. The assessments contained herein are the expression of an independent and collegial reviewing by the committee. UNIT PRESENTATION Unit name: Unit acronym: Requested label: Application type: Laboratoire Physico-Chimie Curie PCC UMR Renewal Current number: UMR 168 Head of the unit (2017-2018): Project leader (2019-2023): Mr Maxime DAHAN Mr Maxime DAHAN Number of teams or themes: 14 COMMITTEE MEMBERS Chair: Mr Pierre-François LENNE, CNRS Marseille Experts: Mr Jordi GARCIA-OJALVO, Universitat Pompeu Fabra, Barcelone, Espagne Mr Pascal HEBRAUD, CNRS Strasbourg, (representative of CoNRS) Ms Kinneret KEREN, Technion, Israel Institute of Technology, Israel Ms Agnès PIEDNOIR, CNRS Villeurbanne (supporting personnel) Mr Olivier THEODOLY, CNRS Marseille Mr Roland WEDLICH-SÖLDNER, Universität Münster, Allemagne Ms Nathalie WESTBROOK, Université Paris Sud, (representative of CNU) HCERES scientific officer: Mr Christian BORDAS Representatives of supervising institutions and bodies: Ms Geneviève ALMOUZNI, Institut Curie Mr Alexandre LEGRIS, CNRS Mr Bernard PERRIN, université Pierre et Marie Curie 3

Laboratoire Physico-Chimie Curie, PCC, U PARIS 6, INST CURIE, CNRS, Mr Maxime DAHAN INTRODUCTION HISTORY AND GEOGRAPHICAL LOCATION OF THE UNIT The laboratory Physico-Chimie Curie (PCC, UMR168) was created in 1996 with the aim of developing and applying physical concepts, particularly soft-matter and statistical physics, to the study of living systems. The unit is located at the heart of the Paris site of the Institut Curie, specifically in the Pavillon Curie, one of the two original buildings of the Institut du Radium founded by Marie Curie in 1909. Over the past 20 years, under the successive leadership of Mr Jacques PROST, Mr Jean-François JOANNY and Mr Maxime DAHAN, the unit has increased significantly in size and now counts about 110 people. MANAGEMENT TEAM Mr Maxime DAHAN (director) and Mr Axel BUGUIN (deputy-director). HCERES NOMENCLATURE ST2 Physics SVE Life and environment sciences SCIENTIFIC DOMAIN The research unit aims at understanding the physical and physicochemical mechanisms that underpin biological systems. Within this framework, the research topics cover biomimetic and reconstituted systems to cell biology, physical approaches to developmental biology, nuclear biology, immunology as well as translational research and clinical applications. 4

Laboratoire Physico-Chimie Curie, PCC, U PARIS 6, INST CURIE, CNRS, Mr Maxime DAHAN UNIT WORKFORCE Unit workforce Number 30/06/2017 Number 01/01/2019 Permanent staff Full professors and similar positions 2 2 Assistant professors and similar positions 4 4 Full time research directors (Directeurs de recherche) and similar positions Full time research associates (Chargés de recherche) and similar positions Other scientists ( Conservateurs, cadres scientifiques des EPIC, fondations, industries, etc. ) 13 13 10 9 0 0 High school teachers 0 0 Supporting personnel (ITAs, BIATSSs and others, notably of EPICs) 11 11 TOTAL permanent staff 40 39 Non-permanent staff Non-permanent professors and associate professors, including emeritus 3 Non-permanent full time scientists, including emeritus, post-docs 28 Non-permanent supporting personnel 6 PhD Students 31 TOTAL non-permanent staff 68 TOTAL unit 108 GLOBAL ASSESSMENT OF THE UNIT The PCC unit is a vibrant unit gathering physicists, physical chemists and biologists that aim to uncover the physical principles that govern biological systems. By combining theoretical expertise, statistical physics in particular, with sophisticated experimental approaches, they have significantly contributed to the understanding of living matter, after decades dominated by molecular genetics. The combination of a solid theoretical framework and elegant experiments is still quite unique in the world and therefore attracts talented young researchers. Recent recruitments and turnover of the groups have led to the development of new themes since the last evaluation. By maintaining also internationally recognized topics, the unit has thus succeeded to maintain a leading position in a rapidly evolving field. The ability to develop sophisticated experimental approaches and technologies for fundamental and medical research is also a strong and recognized asset to the unit. The unit should maintain its strategic position by reinforcing and extending work combining, as much as possible, experiments and theory, which is the recognized strength of the unit. 5

The evaluation reports of Hceres are available online: www.hceres.com Evaluation of clusters of higher education and research institutions Evaluation of higher education and research institutions Evaluation of research Evaluation of doctoral schools Evaluation of programmes International evaluation and accreditation