MACP TECHNOLOGY STRATEGY DIGITAL HEALTH INITIATIVE

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MACP TECHNOLOGY STRATEGY DIGITAL HEALTH INITIATIVE January 7, 2016

Brief Recap: MACP Technology Strategy & Digital Health Initiative 2 The Challenge and Opportunity: Innovation economy will drive long-term growth in MA Life sciences has seen significant success and growth MA is lagging other states in tech VC funding for tech in MA is lagging both California and New York Early-stage seed capital is also lagging in MA How can Massachusetts through a public private partnership support tech innovation to help create a new cluster similar to biotech? The Process for a Broad Tech Strategy: MACP engaged academic, industry, and VC leaders to develop a strategy to bolster tech in MA MACP developed an 10 point strategy to support tech innovation in MA around key priority areas A critical element of the strategy is a focused effort in Digital Health Plays to our regional strengths in tech Ties in elements from our key priority areas Can serve as an early win for MA.

Massachusetts Digital Health Initiative: What is Digital Health? 3 Digital Health captures the intersection of health-related industries and the ways in which IT is transforming the future of healthcare. $32.4 billion market opportunity in the next decade* Convergence of Trends/Tech Wide Range of Applications Personalized medicine Big data Security and privacy Social networks for healthcare Biosensors Electronic medical records Personal health records mhealth/telehealth Expenses billing and costs Social platforms/gaming Data analytics/integrative solutions Fitness technology *Does not include consumer wearables, IT solutions or data-analytics platforms, all of which are individually muti-billion dollar markets. Goldman, Sachs & Co. report, The Internet of Things Vol. 5, The Digital Revolution Comes to U.S. Healthcare, June 29, 2015.

Digital Health Steering Committee 4 Jeff Leiden, Chair Chairman, President and CEO, Vertex Bill Swanson Chair, MACP Robert Kraft Chairman and CEO, The Kraft Group (MACP) Joe Tucci Chairman, President and CEO, EMC (MACP) John Fish Chairman and CEO, Suffolk Construction Co. (MACP) David Torchiana President and CEO, Partners Healthcare (MACP) Dan O Connell President and CEO, MACP Bryan Jamele Executive Vice President, MACP Steering Committee John Barros Chief of Economic Development, City of Boston John Brownstein Chief Innovation Officer, Boston Children s Hospital Jonathan Bush Co-Founder, CEO and President, athenahealth Jeff Bussgang General Partner, Flybridge Capital Partners Andrew Dreyfus President and CEO, Blue Cross Blue Shield of MA Tom Ferry President and CEO, Curaspan David Fialkow Managing Director, General Catalyst Partners Sharon Gillett Principal Networking Policy Strategist, Microsoft Jeff Golden, M.D. Chair, Pathology, Brigham and Women s Hospital Kerry Healey President, Babson College Digital Health in MA: Overall Goal Steve Kraus Partner, Bessemer Venture Partners Jeff Leerink Founder, Chairman and CEO, Leerink Partners Marty Meehan President, University of Massachusetts Elizabeth Nabel, M.D. President, Brigham and Women s Health Care Amir Nashat Managing Director, Polaris Partners Liz Reynolds Executive Director, MIT IPC Martin Schmidt Provost, MIT Katie Stebbins Assistant Secretary of Innovation, Technology and Entrepreneurship, EOHED Michael Weintraub President and CEO Optum Analytics (Humedica) Krishna Yeshwant General Partner, Google Ventures To identify and support strategies to leverage regional strengths and create a leading global center for Digital Health companies, innovation and practice

Academic Committee 5 The Academic Committee will explore ways to better leverage our universities and the role they play in moving innovative tech ideas into the marketplace Members of the Committee: Kerry Healey, Chair President, Babson College Jeff Leiden Chairman, President and CEO, Vertex Bill Swanson Chair, MACP David Altshuler Executive VP and Chief Scientific Officer, Vertex Abi Barrow Director, The Massachusetts Technology Transfer Center Chris Coburn Vice President, Innovation, Partners Healthcare Karen Gleason Associate Provost and Professor, MIT Isaac Kohlberg Senior Associate Provost and Chief Technology Development Officer, Harvard University Marc Meyer Co-Director of the Center for Entrepreneurship Education and Professor, Northeastern University Amir Nashat Managing Director, Polaris Partners Daniel O Connell President and CEO, MACP David Redlick Senior Counsel, WilmerHale Carmichael Roberts Entrepreneur and General Partner, North Bridge Venture Partners Kumble Subbaswamy Chancellor, University of Massachusetts Amherst Krishna Yeshwant General Partner, Google Ventures Standardized Agreement Templates Working Group: Steve Barrett WilmerHale Daniel Dardani MIT Meghan Fenno Harvard University Sam Liss Harvard University Bob MacWright UMass Amherst Michael Malone UMass Amherst Lita Nelsen MIT Craig Newfield MIT Paige Goodwin Vertex

Massachusetts Digital Health Initiative: Near-term Initiatives 6 Speaker Series at local universities partner large and small company CEOs Mentorship program Elected officials, venture capitalists, academic leaders, private sector and entrepreneurs Sponsorship Mentorship Networking Convening & Legislative Engagement Funding Digital Health in MA Private, state and city funding initiatives Academic Initiatives Accelerator Space Dedicated accelerator space and management for DH startups in MA Standardized templates/processes: Tech transfer Sponsored research collaborations 6

Key Private Sector Announcements 7 1. Funding. To address the need for support for local companies, we are working on an innovative approach to provide private funds for digital health companies that are starting up, located in, or planning to re-locate to Massachusetts. 2. Standardized Digital Health Agreements. We have created standardized template agreements, each accompanied by a user-friendly guide, in the areas of software and technology licensing and sponsored research in digital health. MIT, Harvard, Northeastern, UMass and Partners Healthcare contributed to and approved these agreements. The template agreements and user guides are posted on MeHI's digital health website at http://massehealth.org/industry/agreement-templates 3. Mentorship Speaker Series. MACP will host a second year of its statewide mentorship speaker series to connect high-level, established executives with entrepreneurs of emerging companies to discuss how to start and grow a successful tech business in Massachusetts. This year s series will have a focus on digital health and will include events in Worcester and the Springfield area. 4. Digital Health Innovation Hub. MACP is partnering with the City of Boston, MeHI and MassChallenge to create the Digital Health Innovation Hub that will provide digital health startups with space, programming and a strong industry network to tap into. The space will also serve as a venue for the industry to convene events and host networking opportunities. MassChallenge will be a key partner in managing and operating the Hub.