ETHICON Wound Closure Suture Products. ETHICON Wound Closure Suture Products. International Market Development

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1 ETHICON Wound Closure Suture Products ETHICON Wound Closure Suture Products International Market Development 2004

2 TAPERCUT* Needle Precision Point The ETHICON Wound Closure Products Information Booklet is provided by ETHICON International Market Development Precision Cosmetic- Conventional Cutting PRIME MICRO-POINT* Spatula Needle International Market Development Conventional Spatula CS ULTIMA* Spatula Needle VISI-BLACK* Needle SABRELOC* Spatula Needle MICRO-POINT* Reverse Cutting Needle

3 Surgical Suture Needles Needle Shapes ¼ Circle ⅜ Circle ½ Curve ½ Circle Taper Point Needle Conventional Cutting ⅝ Circle Straight Needle Types ETHIGUARD* Blunt Point Needle Reverse Cutting Contents Page ABSORBABLE Sutures Surgical Gut Suture Plain 2 Surgical Gut Suture Chromic 3 Coated VICRYL* Rapide (polyglactin 910) Suture 4 MONOCRYL* (poliglecaprone 25) Suture 5 Coated VICRYL* (polyglactin 910) Suture 6 Coated VICRYL* Monofilament Suture 7 Coated VICRYL* Plus Antibacterial (polyglactin 910) Suture 8 PDS II* (polydioxanone) Suture 9 Wound Closure Chart NON-ABSORBABLE Sutures PERMA-HAND* Silk Suture 12 Surgical Steel Suture 13 NUROLON* Braided Nylon Suture 14 ETHILON* Nylon Suture 15 MERSILENE* Polyester Fiber Suture 16 ETHIBOND* Excel Polyester Suture 17 PROLENE* Polypropylene Suture 18 PRONOVA* poly (hexafluoropropylene-vdf) Suture 19 Surgical Suture Needles * Trademark

4 Surgical Gut Suture - Plain PRONOVA Suture Surgical Gut Suture - Plain Beef Serosa or Sheep Submucosa Natural Virtual Monofilament Absorbable Yellowish - Tan Available Size Range 3 7/0, Fast Absorbing Gut sizes 5/0-6/0 Strength Retention Approximately 7-10 days post-op Fast Absorbing Gut = Approximately 5 7 days post-op Absorbed in 70 days, Fast Absorbing Gut in days Proteolytic enzymatic digestion Ligation of superficial vessels; suture subcutaneous and that heal rapidly. Ophthalmology. Fast Absorbing Gut for external use only. Provides effective short-term wound support. Consistently smooth strands allow for easy tie down, minimizing fraying. PRONOVA Suture Polymer blend of poly (vinylidene fluoride) and poly (vinylidene fluoride-cohexafluoropolypropylene) Monofilament Blue and Clear Available Size Range 2 through 10/0 Strength Retention Indefinite Non-absorbable Vascular anastomoses and general surgical indications Less susceptible to handling damage than other monofilament sutures. Minimal package memory. Strong, smooth monofilament suture

5 PROLENE Suture Surgical Gut Suture - Chromic Polypropylene PROLENE Suture Surgical Gut Suture - Chromic Beef Serosa or Sheep Submucosa Monofilament Natural Virtual Monofilament Absorbable Chromic Salts to retard absorption Blue and Clear Available Size Range 2 through 10/0 Strength Retention Indefinite Non-absorbable General, plastic, cardiovascular surgery and skin closure; ophthalmology Unique CONTROLLED LINEAR ELONGATION gives the surgeon a built-in indicator of appropriate knot tension when tying. Plastic knot deformity provides for secure surgical knots. PROLENE suture is the most commonly used polypropylene cardiovascular suture in the world. Natural Brown and Dyed Blue Available Size Range 3 7/0 Strength Retention Strength retention for approximately days post-op Absorbed in 90 days Proteolytic enzymatic digestion Ligation of superficial vessels; suturing of subcutaneous and other rapid healing. Ophthalmology. TRU-GUAGING ensures consistent strand from batch to batch. TRU-CHROMICIZING ensures consistent, predictable absorption. Dyed blue for ophthalmic surgery

6 Coated VICRYL RAPIDE Suture ETHIBOND Excel Suture Coated VICRYL RAPIDE Suture Polyglactin 910. Copolymer of 90% glycolide and 10% L-lactide Braided Absorbable 50% Polyglactin 370 and 50% Calcium Stearate Undyed Natural Beige Available Size Range 1 through 5/0 Strength Retention 50% of original strength 5 days post-op 14 days post-op Completely absorbed in 42 days Hydrolysis Superficial soft tissue approximation of the skin and mucosa where short term wound support is required Provides effective short-term wound support. Fastest absorbing synthetic absorbable suture available from ETHICON. Soft, comfortable suture in delicate. ETHIBOND Excel Suture Polyester / Dacron Braided Polybutilate Green and White Available Size Range 5 through 7/0 Strength Retention Indefinite General surgery, cardiovascular and plastic surgery; retention ETHIBOND Excel suture is stronger than any other braided polyester suture. Superior pliability when compared to competitive products. has a natural affinity to the suture, will not flake off like silicone coatings. Unique polybutilate coating provides for optimal tie down

7 MERSILENE Suture MONOCRYL Suture MERSILENE Suture Polyester / Dacron Braided and Monofilament MONOCRYL Suture Poliglecaprone 25 (copolymer of glycolide and e-caprolactone) Monofilament Absorbable Green and White Available Size Range Braided 5 through 6/0 Monofilament 10/0 11/0 Strength Retention Indefinite General surgery, cardiovascular and plastic surgery; retention EXCLUSIVE size 10/0 and 11/0 for ophthalmic surgery. Outstanding strength and reliability. White MERSILENE suture is the common suture of choice for tendon surgery. Undyed - Beige and Dyed - Violet Available Size Range 2 through 6/0 Strength Retention Undyed - 7 days post-op 14 days post-op Dyed - 7 days post-op 14 days post-op Completely absorbed in days Hydrolysis General soft tissue approximation and/or ligation. MONOCRYL suture is pliable and easy to handle and tie. Provides effective short to medium-term wound support. Excellent knot security for a monofilament suture

8 Coated VICRYL Suture ETHILON* Nylon Suture Coated VICRYL Suture Polyglactin 910 (copolymer of glycolide and lactide) Braided Absorbable 50% Polyglactin 370 and 50% Calcium Stearate Violet and Undyed Natural Beige Available Size Range 3 through 8/0 Strength Retention 75% of original 14 days post-op 50% of original 21 days post-op 25% of original 28 days post-op (Sizes 6/0 and larger) Absorbed in days, 63 days on average Hydrolysis General soft tissue approximation and/or ligation, including use in ophthalmology Coated VICRYL suture is the most commonly used synthetic absorbable suture in the world. Easy, secure knot tying, as knots snug into place and hold tight. Unique 28-day Strength Retention claim. Referenced in over 2000 clinical papers Nylon 6 ETHILON Nylon Suture Monofilament Black, Green and Clear Available Size Range 2 through 11/0 Strength Retention Approximately 20% loss per year. Skin closure: retention; Plastic surgery, ophthalmology and microsurgery Pliabilised for ease of handling and tying. Medical grade nylon is strongest available for sutures. Attached to outstanding ETHICON Surgical needles

9 NUROLON Braided Nylon Suture Monofilament Nylon 6 NUROLON Braided Nylon Suture Braided Black Available Size Range 1 through 6/0 Strength Retention Approximately 20% loss per year Ligation and general closure; neurosurgery Nylon 6 is the strongest nylon available for medical use. Available on CONTROL RELEASE* surgical needles. Originally developed exclusively for the neurosurgeon as a synthetic alternative to silk suture for use around the brain, but has been utilized in many other surgical specialties Coated VICRYL Suture Coated VICRYL Suture Polyglactin 910 (copolymer of glycolide and lactide) Monofilament Absorbable Violet and Undyed Natural Beige Available Size Range 9/0 and 10/0 Strength Retention 75% of original 14 days post-op 40% of original 21 days post-op Absorbed in days, 63 days on average Hydrolysis Ophthalmic and microsurgery indications Monofilament provides smooth passage through soft, delicate

10 Surgical Steel Suture Coated VICRYL Plus Suture Polyglactin 910 (copolymer of glycolide and lactide) Braided Absorbable Polyglactin 370 and IRGACARE MP (triclosan) Violet and Undyed Natural Beige Available Size Range 1 through 6/0 Strength Retention 75% of original 14 days post-op 50% of original 21 days post-op 25% of original 28 days post-op Absorbed in days, 63 days on average Hydrolysis General soft tissue approximation and/or ligation Offers protection against bacteria colonization of the suture. Suture contains IRGACARE MP, the purist form of the broadspectrum antibacterial agent triclosan. First and only anti-bacterial suture. Surgical Steel Suture 316L Stainless Steel Metal Alloy Metallic Silver Available Size Range 7 10/0 Strength Retention Indefinite Monofilament Abdominal wall and skin closure; retention; tendon repair; orthopaedic & neurosurgery. Sternum closure in cardiovascular surgery Wire is drawn at ETHICON to ensure highest quality product from raw material to finished goods. Available on unique CCS and CCS-1 sternum closure needles. Packaged in multi-stand put-ups for user convenience and minimal waste

11 PERMA-HAND Silk Suture PDS II Suture PERMA-HAND Silk Suture Natural protein fibre of raw silk spun by silkworms Polydioxanone PDS II Suture Natural Braided Bees wax Monofilament Absorbable Black and White Available Size Range 5 through 9/0 Strength Retention Strength retention for approximately 1 year Ligation and general closure; general surgery. Ophthalmology, plastic surgery and neurosurgery Slow controlled braiding for consistency of diameter smooth easy passage through. All strands are de-gummed strength and consistency. Silk is sourced from our own manufacturing plant at Johnson & Johnson Medical in China. Available Size Range Strength Retention Undyed Clear and Dyed Violet 2 through 9/0 dyed 1 through 7/0 undyed 75% of original 2 weeks post-op 50% of original 4 weeks post-op 25% of original 6 weeks post-op Absorbed in days Hydrolysis Soft tissue approximation, including use in pediatric cardiovascular tissue where growth is expected to occur; ophthalmic surgery At 42 days post-op, PDS II suture has more than twice as much strength as Maxon and Biosyn. Smooth easy passage through. Less out-of-package memory than competition. Outstanding pliability in a monofilament suture

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