The Netherlands Life Sciences Gateway to Europe

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1 The Netherlands Life Sciences Gateway to Europe

2 WHY FOREIGN LIFE SCIENCE COMPANIES INVEST IN THE NETHERLANDS Centrally located between Germany, France and the UK with a highly efficient (logistics) infrastructure Strong network of excellent R&D partners and medical care clusters Innovative life sciences infrastructure and knowledge base Attractive R&D incentives; R&D Tax Credits Innovation Loan Innovation Box with effective tax rate of 5% Favorable tax system with competitive tax rate and interesting IP tax planning possibilities Outstanding International Business Climate Availability of highly educated and multilingual personnel

3 CENTRAL TO MARKETS Europe is the 2nd largest health care market worldwide (33%) The Netherlands is located in the center of the largest health care markets in Europe The Netherlands has more than 16,6 million inhabitants and, moreover, app. 170 million people live within a 300-mile radius of Amsterdam. Amsterdam Schiphol Airport is Europe s 3rd largest cargo airport Seaport Rotterdam is Europe s biggest container port United Kingdom: 20bln France: 10bln The Netherlands Germany: 20bln Italy: 7bln Spain: 5,5bln Health care spend 2010: Top 5 Countries (in Euro) Source: Eucomed 2010

4 KNOWLEDGE BASE Integrated life sciences innovation First rate academia, hundreds of SMEs and global players in med-/biotech and pharma within a 120 mile radius 120 mile radius Focal points Amsterdam Eindhoven/Maastricht Groningen Leiden/Delft/Rotterdam Medical Delta Utrecht Nijmegen/Enschede World class The Medical Delta is 5th in the European Top 15 regions for medtech patent applications Global players & high concentration of SMEs Excellent biobanks and real life data infrastructure Source: OECD REGPAT database

5 HIGH QUALITY RESEARCH 12 Research Universities Average ranks 8 th in the world 8 University Medical Centers (UMC s) Employees 60,000 Medical students 31,000 Publications 7,500 (annually) Clinical studies 2,000 (annually) Areas of expertise in Medical technology Minimally invasive techniques Medical optics Medical imaging and image processing High precision instruments Safe extramural care Source: Ranking Web of World universities l NFU.nl l FP7

6 FAVORABLE TAX CLIMATE Favorable tax treaty with the US, and extensive tax treaty network worldwide Relatively low statutory corporate income tax rate of: 25% (20% on the first ) Possibility of obtaining advanced tax rulings from the Dutch tax authorities giving certainty on future tax positions R&D specific incentives Innovation box: 5% effective tax rate on result of the income derived from IP R&D allowance (WBSO): compensation for R&D labor costs Innovation loan Source : Source: NFIA

7 DUTCH MEDICALTECHNOLOGY COMPANIES Listed on the Stock Exchange with world leading positions: Philips Healthcare DSM Delft Imaging Royal Philips Electronics of the Netherlands is a diversified Health and Well-being company. As a world leader in healthcare, lifestyle and lighting, Philips integrates technologies and design into people-centric solutions. It focuses on a wide range of therapeutic areas. DSM is a Life Sciences and Materials Sciences Company and has four strategic business units with relevance to medical technology, which are DSM Biomedical (builds on the expertise and strengths of DSM in polymers, coating technology, materials science and life sciences to meet the upcoming needs of the medical and biotech industries), DSM Medical Coatings, DSM Dyneema (developed a new strong high performance polyethylene fibre), and DSM Engineering Plastics (produces thermoplastics for barrier packaging, closures and components). Delft Imaging Systems is part of Delft Diagnostic Imaging and finds its origin from Oldelft, the company that introduced the world-famous Odelca chest screening camera system in Delft Imaging Systems is constantly developing new services and products for customers around the globe, has sufficient and adequate facilities and highly qualified personnel to carry out the specific training and application courses for the equipment involved. Delft Imaging Systems is the only imaging company worldwide to invest in solutions that assist the medical community in the fight against tuberculosis.

8 FOREIGN MEDICAL TECHNOLOGY COMPANIES IN THE NETHERLANDS European headquarters Sales and Marketing Research and Development American Medical Systems Boston Scientific American Medical Systems Distribution Center Biomet Atrium Cordis BSN Medical Datascope Biomet Datascope Conmed Hollister Cameron Health Dionex Minntech Idexx Laboratories Coherent GE Medical Systems Idexx Laboratories Ophthalmic Imaging Systems Cryocath Technologies Hollister Medicom Medicom Idexx Laboratories Imaging Dynamics Medtronic Medtronic Medrad Kinetic Concepts Merge Healthcare Performance Systematix Merge Healthcare (EMEA) Ophthalmic Imaging Systems Oliver Medical Packaging Minntech Medtronic Osteotech Stryker Pioneer Surgical Technology Pioneer Surgical Technology Palomar Medical Technologies Pioneer Surgical Technology Sunrise Medical Scanlan International Raymedical Toshiba Medical Systems Thermo Fisher Scientific Spectranetics ResMed Uroplasty Toshiba Medical Systems Toshiba Medical Systems Spectrum Vitatron Transmedics

9 ABOUT THE NFIA Founded 30 years ago, the NFIA is an operational unit of the Dutch Ministry of Economic Affairs, Agriculture and Innovation. Throughout the years it has supported thousands of companies from all over the world to successfully establish their business in the Netherlands. NFIA can help your soft landing in Europe by providing tailor made advice, information and practical assistance, free and confidentially. We can help among others with: site selection, introductions to partners, local government and business leaders. Contact us to learn more about opportunities for your company in Holland! Katja Berkhout Area Director New England and Eastern Canada Netherlands Foreign Investment Agency Boston, MA T C F katja@nfia.com