Health Innovations in Horizon 2020: the framework programme for research and innovation ( )

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1 Health Innovations in Horizon 2020: the framework programme for research and innovation ( ) Virginija Dambrauskaite, MD, PhD Scientific Officer, Medical Research Unit, Health Directorate Directorate-General for Research & Innovation European Commission

2 What Horizon 2020 is about Responding to the economic crisis Addressing people s concerns Strengthening the EU s global position

3 Horizon 2020 timeline From 30/11 Parliament and Council negotiations on the basis of the Commission proposals On-going Parliament and Council negotiations on EU budget (including Horizon 2020) By end 2013 Adoption of legislative acts by Parliament and Council on Horizon 2020 January 2014 Horizon 2020 starts; launch of first calls 2014

4 More money for health research in times of austerity? Investing into the right research pays off: Simpler, more personalised and cost-efficient technologies and treatments Fewer chronic patients New technologies, companies and markets Higher share of radical innovation Large returns on investment New skilled jobs in high value-added sectors

5 Horizon 2020 and the Health, Demographic change and Wellbeing challenge Adapting to an ageing population Pursuing the path to more personalised medicine Harnessing and encouraging private sector capability Coordinating national efforts Expanding global cooperation

6 Health, Demographic change & wellbeing -the Commission's proposal for Horizon 2020 Understanding health determinants Improving health promotion & disease prevention Developing effective screening programmes Improving the assessment of disease susceptibility Improving surveillance and preparedness Understanding disease Developing better preventive vaccines Improving diagnosis Using in-silico medicine for improving disease management and prediction Treating disease Transferring knowledge to clinical practice and scalable innovation actions Better use of health data Improving support for policy-making and regulation Active ageing, independent and assisted living Individual empowerment for selfmanagement of health Promoting integrated care Optimising the efficiency and effectiveness of healthcare systems Reducing inequalities through evidence based decision making Dissemination of best practice, and innovative technologies and approaches.

7 The challenges ahead Cancer, chronic and degenerative diseases gain importance in the context of the ageing population More than 70% of healthcare spending on chronic diseases Wanted: ways of keeping our healthcare costs stable and our healthcare systems running EU must catch up with global health innovation leaders and keep its biomedical industry

8 The FP7 Health Programme The largest multi-national fund: to fund collaborative research to fund international consortia and publicprivate partnerships to fund excellent research and innovation in applied fields involving leading players from Europe and across the globe to tackle key health challenges which are too important or large for any one country to address alone

9 FP7 Health state of play 3.3 billion EUR currently invested in 713 on-going projects Some 2,900 organisations from 122 countries involved Leading role in 6 international research consortia 1 billion EUR investment in Europe's largest public-private initiative for better and safer medicines

10 Public Private Partnerships the Innovative Medicines Initiative IMI is the worldlargest Public- Private Partnership in health sciences research

11 508 Academic & research teams 92 SMEs IMI State of play 341 EFPIA teams 603 million EUR IMI JU cash contribution 17 patient org 10 regulators 600 million EUR EFPIA in kind contribution Imaging biomarkers: the next generation of surrogate end points? ~ 3500 researchers > 200 publications Models for target validation of breast, prostate and lung cancers

12 Enhancing the innovation impact of results Boosting the translation of health research projects' results into innovative applications for health (Inno-2). Sergej Khackimullin # Source: Fotolia.com Aimed at exploiting results from projects funded within FP6 and FP7 Providing the viability of new methods, technologies, models or prototypes Up to 5 patners and 6 million SMEs in the driving seat Bridging the gap between successful prior research and the earlierst stage of a marketable innovation 95 million

13 FP7 Health The concept of social innovation To promote better quality of life and improved well-being for the elderly through innovative holistic approaches that meet social needs and create new social relationships Examples: The development of a personalised strategy for reducing risks to developing dementia. The development of personalized electronic tools for effective virtual rehabilitation environment after a stroke. The development of an approach for health literacy for ageing people, through the use of modern media and e-health applications. The development of social innovations to improve the quality of life and well-being of older people.

14 Novel solutions to overcome bottlenecks to innovation Horizon2020 aims to optimise the efficiency and effectiveness of health systems through the development of health technology assessment, health economics and innovative technologies and approaches in the healthcare sector. Identification of the major bottlenecks to innovation in the area of research on health care systems Finding solutions for creating a sustainable, cost effective and efficient health care system

15 Empowering people, driving change Behavioural change is critical to the prevention, management and treatment of many important health conditions and improves health outcomes, as well as cost savings to healthcare systems. Finding the best approach to empower people to make the behavioural changes required

16 Scaling up innovative solutions Horizon 2020 aims to scale up innovative solutions to overcome the challenges and barriers to preventive health and to ensure that innovative and effective products reach the market. Attracting stakeholders such as SMEs, industry and other sectors to innovation and ensure they become part of the solution

17 Implementing Open Innovation Horizon 2020 will support the full spectrum of activities throughout the research and innovation cycle from knowledge and technology transfer to large scale demonstration actions, leading to scalable solutions for Europe and beyond. Implementing Open Innovation in Horizon 2020 Consider the benefits and risks of Open Innovation in EU health research

18 Collaborative projects Simpler Simpler programme architecture, a single set of rules Easy to use cost reimbursement model: one unique funding rate Less paperwork in preparing proposals Reduce time to grant by 100 days More inclusive More support for innovation and activities close to the market Strong focus on creating business opportunities

19 Special support for SMEs ~5 billion EUR in H2020 Inspired by the US model "SBIR" Challenge driven, bottom up A single company can be funded 3 phases / 3 entry points: Concept and feasibility assessment R&D, demonstration, market replication Commercialisation

20 In the pipeline: public-private partnership for innovative health research Based on the successes of the Innovative Medicines Initiative (IMI) Legislative proposals only after Horizon 2020 approval Organisation and structure to be defined Your view matters (public consultation closed on 4 th October)

21 Thank you!

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