Health and Fitness Analog solution. Wenbin Zhu Medical BDM June, 2015

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1 Health and Fitness Analog solution Wenbin Zhu Medical BDM June,

2 A Broad Market TI in Medical Devices Today

3 TI HealthTech Engineering components for life. TI Solutions for Wearable Optical Bio-Sensing - Industry s Lowest Power - Industry s Best PPG signal quality - Fitness parameters beyond just HR

4 What s Pulse Oximeter Pulse oximeters are non-invasive devices used to measure blood-oxygen saturation level. In blood, oxygen is carried by Hemoglobin(Hb), named HbO2, Oximeter uses PPG(Optical) to measure saturation level of HbO2. PPG: Oxygenated blood HbO2 has wavelength dependent absorption characteristic, absorption also depends on oxygen saturation level. Typical value is from 90% to 100%, can be lower to 60%.

5 EE Types of Pulse Oximeter Clinical health Patient Monitor(Pulse Oxi module) Home health / Telehealth Finger clip Pulse Oxi Portable Pulse Ox(including Watch type) Sport and Fitness Wrist trap Pulse Oxi(HRM) Watch type Pulse Oxi(HRM)

6 AFE44xx TI provides complete portfolio of Integrated photometry solution from Clinical/home health SpO2 to sports/fitness HRM. AFE4490 Released AFE4400 Released AFE4403 Released AFE4404 Clinical Monitoring SpO2 Reduced Features Home Health & Fitness SpO2 3.18mm x 3.18mm x 0.5mm WCSP package Vled_sup = Vfb + 0.5V Sports & Fitness HRM 2.6 mm x 1.6 mm, DSBGA I2C Sports & Fitness HRM

7 AFE4403 Integrated Solution for Optical HRM & home pulse-ox) Features Transmitter H-Bridge & Push/Pull LED Driver Config Dynamic range >95dB 8 bit programmable LED current 0 to 100mA Option for 3 rd LED support Min LED on time 50uS Low power transmitter (100uA + Average LED current) Receiver Pulse frequency 62.5Hz to 5000Hz Programmable TIA gain Low Power Receiver (<700uA) with 13 noise free bits. Min Receiver sample time 50uS Dynamic cycle-to-cycle power saving mode Digital ambient estimation and subtraction (separate RED/IR ambient values) Other Features Flexible Pulse Sequencing and Timing Flexible clocking (4-60MHz clock input) Cable On/Off detect Supplies (Rx: 2V to 3.6V, Tx: 3.3V to 5.25V) -20 C to 70 C Compact WCSP (3mm x 3mm x 0.5mm)

8 AFE4404 Ultra-small, Integrated AFE for Wearable Optical Bio-sensing Features Transmitter Supports common anode LED configurations Better than 100 db of dynamic range 6-bit programmable LED current to 50 ma Programmable LED On-time Simultaneous 3rd LED support for optimized SPO2/HRM or multi-wavelength HRM Receiver 24-bit representation of the current input from a photodiode in Twos complement format Individual DC offset subtraction DAC at TIA input for each LED and ambient phase Digital ambient subtraction at ADC output Programmable transimpedance gain from 10K-2M 100 db of dynamic range Dynamic power saving mode to reduce current to less than 300 ua Other Features Pulse frequency 10 SPS to 1000 SPS Flexible pulse sequencing and timing control Flexible clock options: External clocking: 4-60 MHz input clock Internal clocking: 4 MHz oscillator I2C interface Supplies (Rx: 2-3.6V, Tx: 3-5.2V, IO: V) Package: 2.6mmx1.6mm WCSP package, 0.5 mm pitch Specified Temperature Range: 20 C to 70 C

9 Challenges Summary TI Solution Competition Low power for longer battery life Skin tone variation Best signal for Motion cancellation Algorithms Performance with Glass Low temperature performance Ambient noise AFE4404 enables the acquisition of the industry s best PPG signal at wrist across skin tones, enabling the acquisition of robust parameters beyond heart rate at 90% lower LED current than competition!! TI Information - NDA

10 ADS1291/2 ADS1191/2 Heart Rate Monitor Based on Bio-Potential Measurements

11 Reliable Continuous Heart Rate Monitoring : Where and How?? Patch Chest Strap Tread Mill Ear buds Strap Strap Watches Challenges for each approach Bio-potential Two (or 3) contacts with 2 to 4 inch separation Motion artifacts Dry Vs Wet electrodes Location Photometry Optimal sensor placement Ambient light Motion artifact Power consumption Pulse-Ox Clips Key Careabouts - Convenience - Accuracy - Battery life - Connectivity A multi-faceted problem needing innovations in sensors, precision instrumentation and sophisticated algorithms! TI Information - NDA

12 ADS1291 ADS1292 Complete Integrated AFE for Bio-potential based HRM Features Fully Integrated ECG Solution Multiple Channels with low noise PGA and 24-bit ADC ADS1291: 1 channel ADS1292: 2 channels Test Signals, RLD Amp, Oscillator, Reference Noise: 8uV p-p (150Hz BW, G=6) CMRR : 105dB with G = 6 Continuous Lead Off detect option Pace Detect Channel Select (HW / SW) Low Power Less than 350µW Nap mode available on ADS Bit ADS1191 and ADS1192 also available Benefits 95% less PCB space necessary for 8-channel solution over discrete implementations Provides immediate notification if electrode becomes disconnected. Insures correct measurement even if external pacer is present. 95% less power than discrete solutions! Power down and standby options lengthen battery life for Holter and other portable applications. ADS1292 Applications Medical Instrumentation (ECG and EEG) including: Patient monitoring: 1-channel ECG, heart-rate, AED Portable sport and fitness applications ADS1292 Packages: 32-pin TQFP (7mm x 7mm) TI Information - NDA

13 BioPotential AFE Roadmap 8 ADS bit, 8kSPS ADS bit, 32kSPS ADS1298R 24-bit, 32kSPS ADS bit, 16kSPS Number of Channels ADS bit, 8kSPS ADS bit, 8kSPS ADS bit, 32kSPS ADS bit, 32kSPS ADS bit, 6.4kSPS NEW ADS1296R 24-bit, 32kSPS ADS1294R 24-bit, 32kSPS 2 ADS bit, 2kSPS ADS bit, 2kSPS ADS1292R 24-bit, 2kSPS 1 ADS bit, 2kSPS ADS bit, 2kSPS 16-bit Resolution 24-bit Integrated Respiration impedance measurement

14 LMT70: + 0.1ºC Precision Analog Temp Sensor, RTD and Precision NTC Thermistor IC 14

15 LMT70/LMT70A + 0.1ºC Precision Analog Temperature Sensor Features Temperature accuracy/error: ±0.13 C max at 30 C ±0.36 C max from -55 C to 150 C ±0.1 C matching of two LMT70A Power supply 2.0V to 5.5V Power supply current <12uA Linear output slope: -5.19mV/ C Output enable switch 0.88mm x 0.88mm WLCSP package Applications Human Body Temperature Monitor Medical/Fitness Wearables & Thermometer Internet of Things (IoT) Sensor Nodes Industrial RTD (Class AA) or Precision NTC/PTC Thermistor Replacement Heat Cost Allocator Metering Temperature Compensation Benefits Reduce manufacturing cost by eliminating temperature calibration Eliminate sorting of temp sensor for matching drives down production cost Eliminate full-temp range multi-point calibration (unlike RTD/NTC Thermistor) 100x lower power than Precision RTD/NTC Reduce PCB size and system cost LMT70 in WLCSP (4-bump ball grid) 0.88mm x 0.88mm

16 LMT70 / 70A Superior Linearity & Accuracy Linearity: Output vs. Temperature Very linear no needs for complex linearization & expensive sorting of sensors Accuracy vs. Temperature (based on testing of 38 units)

17 LMT70 ±0.1ºC Precision Analog Temp Sensor Medical/Fitness Sport Wearable Application Need or Care About Why LMT70 Super accurate ±0.5ºC from 32ºC to 42ºC Very low power in micro-amp range Smallest footprint Matching accuracy for heat transfer calc ±0.1 C accurate from 32 C to 42 C 12 ua supply current 0.8mm x 0.8mm 4-ball WLCSP 0.1 C matching accuracy [1] Ambient Skin Building [1] LMT70A has device-to-device matching accuracy of 0.1 C

18 Thank you 18

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