Life Sciences Outlook. Long Island 2016

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1 Life Sciences Outlook Long Island 2016

2 Long Island The Long Island life sciences landscape will continue to fuel the economy as firms emerge from Cold Spring Harbor Laboratory in Nassau County, as well as Stony Brook University and Brookhaven National Lab in Suffolk County. Broadhollow Bioscience Foundation is actively seeking space across Long Island for growing biotech firms, cementing Long Island as a leading research corridor. 25A Major lab supply: Clusters of established lab stock with long-time industry presence Huntington 25A Longisland Emerging lab supply: Areas with limited lab stock today that are poised for growth Hempstead 106 Bayshore Life Sciences manufacturing supply: Clusters of manufacturing space devoted to pharmaceutical, biological or medical device & instrument manufacturing 27 Freeport Nassau County The life sciences industry in Nassau County is well positioned for growth as innovation-focused funding from the state solidifies groundbreaking bioscience initiatives and research projects. Nassau County serves as headquarters for Cold Spring Harbor Laboratory, a 125-year-old biomedical nonprofit laboratory, and is home to many lab-based companies such as Mirimus and Certerra. Great Neck-based Northwell Health, the largest employer on Long Island, is expanding rapidly along with its research wing, The Feinstein Institute for Medical Research.The Nassau County life sciences market is mainly comprised of owner-occupied laboratory facilities. Suffolk County Stony Brook University serves as an integral part of the research corridor initiative of Long Island. The National Institutes of Health has awarded Stony Brook University s Center for Biotechnology a three-year, $3 million grant to create the Long Island Bioscience Hub along with Cold Spring Harbor, Brookhaven Laboratories, Codagenix, Traverse Biosciences and Marrowsource. Suffolk County is also home to Brookhaven National Laboratory, a 4 million-square-foot multipurpose research lab facility funded by the U.S. Department of Energy, founded in The majority of life sciences establishments are in owner-occupied facilities in a campus setting. In recent years, pharmaceutical companies have dominated commercial activity growth with the majority concentrated in Western and Central Suffolk. JLL Long Island Life Sciences Outlook

3 Economic scorecard % life sciences to private Year-overyear growth WORKFORCE Total life sciences employment Employment 28, % -2.3% Establishments % 0.9% FUNDING Total life sciences % to total U.S. VC funding $167.4M 2.44% NIH funding $126.4M 1.19% SUPPLY Rentable lab supply % direct vacancy 596,399 s.f. 13.9% Cluster score: 30.0 The number of pharmaceutical and medicine manufacturing establishments in Suffolk increased more than 25 percent since The expanding chemical manufacturing industry in Long Island is the largest of 10 regions in the state and has the second-fastest employment growth rate. Long Island biotech jobs have grown approximately 60 percent since 1960, according to the Long Island Index. Pharmaceutical and medicine manufacturing employment lead life sciences employment growth, having increased more than 50 percent since 2004 in Suffolk. In Nassau, employment in medical and diagnostic laboratories increased more than 40 percent since Life sciences employment composition 29.4% 12.7% Life sciences employment 28, % 17.0% 35.1% non-lab using lab using Pharma Electromedical Instrument MFG Medical Equipment & Supplies MFG Testing Laboratories R&D Medical & Diagnostic Laboratories Life sciences establishment composition 50.6% Life sciences establishments % 3.8% 19.2% Pharma & Medicine MFG Electromedical Instrument MFG Medical Equipment & Supplies MFG Testing Laboratories R&D Medical & Diagnostic Laboratories Life sciences patents for drug, bio-affecting and body treating compositions increased more than 20 percent since 2000 in the metro area. Stony Brook University faculty accounts for numerous patents, and in 2014, the University received 157 rewards from the NIH, worth $48.1 million. 0.5% 7.1% JLL Long Island Life Sciences Outlook

4 Long Island Nassau County Northwell Health fuels economic growth on Long Island The Feinstein Institute for Medical Research, the research wing of Northwell Health, recently joined the Long Island Bioscience Hub. They are the fourth member institution of the national REACH initiative as of April The $300 million Center for Bioelectronic Medicine is being planned for the Nassau Hub area in Uniondale, and will convene scientists and medical experts to commercialize non-drug treatments and research neurodegenerative diseases and cancer. In April 2015, Cold Spring Harbor Laboratory and Northwell Health formed a cancer research partnership in Lake Success, Western Nassau. Northwell Health has invested more than $175 million to expand cancer treatment centers throughout Long Island. Suffolk County Pharmaceutical industry thrives in Hauppauge, drives sales activity Bactolac Pharmaceutical and sister company Sciegen Pharmaceuticals plan to renovate and add 50,000 square feet of storage space onto their recently purchased 92,000-square-foot facility at 330 Oser Ave. in Hauppauge. A&Z Pharmaceutical is planning a $4.9 million expansion at its two buildings in the Hauppauge Industrial Park. The firm wants to add 26,700 square feet to its facility at 350 Wireless Blvd., purchased in 2014, for use as a headquarters. A&Z also plans to lease 6,500 square feet at 180 Oser Ave., where it has offices and manufacturing. Fougera Pharmaceuticals plans to consolidate its local operations into a new $88 million Melville plant that will retain nearly 400 jobs and provide room for additional growth. The project includes expanding, renovating and constructing 30,000 square feet at the Melville facility, and is scheduled to break ground at the end of 2016 to be completed in Canon USA, Inc. is looking to open a genetic testing research center on Long Island in a strategic effort to enter a burgeoning healthcare market amid slowing sales revenues. The proposed laboratory would be part of Canon BioMedical, Inc., a Melville-based subsidiary formed in Facilities scorecard SUPPLY Nassau County Suffolk County Rentable lab stock (% of total stock) Direct vacancy (Change year-over-year) ANGION BIOMEDICA CORP. 51 Charles Lindbergh Blvd. Uniondale 40,000 square feet Term: 15 years Broadhollow Bioscience Park West Cambridge 60,000 square feet Class B Direct Options Activity key: 261,276 s.f. 77.0% 14.8% (0.4) ppts 335,123 s.f. 22.6% 13.2% (0.1) ppts # of large blocks over 100,000 s.f. 0 0 Under construction (s.f.) 0 270,000.f. DEMAND # of requirements Total s.f. requirements PRICING Average asking rent (NNN) (Change year-over-year) Leasing Sales 0 0 s.f. $25.50 p.s.f. 0.7% 2 180,000 s.f. $16.95 p.s.f. 0.0% Bactolac Pharmaceutical 330 Oser Ave. Hauppauge 100,000 square feet Class C $110 per square foot INVAGEN PHARMACEUTICALS 275 Carleton Ave. Islip 125,000 square feet Expected delivery: 2016 Under construction Large blocks of space JLL Long Island Life Sciences Outlook

5 For more information, please contact: Sarah Bouzarouata Research Analyst +1 (631) About JLL JLL (NYSE: JLL) is a professional services and investment management firm offering specialized real estate services to clients seeking increased value by owning, occupying and investing in real estate. A Fortune 500 company with annual fee revenue of $5.2 billion and gross revenue of $6.0 billion, JLL has more than 280 corporate offices, operates in more than 80 countries and has a global workforce of more than 60,000. On behalf of its clients, the firm provides management and real estate outsourcing services for a property portfolio of 4.0 billion square feet, or 372 million square meters, and completed $138 billion in sales, acquisitions and finance transactions in Its investment management business, LaSalle Investment Management, has $58.3 billion of real estate assets under management. JLL is the brand name, and a registered trademark, of Jones Lang LaSalle Incorporated. For further information, visit About JLL Research JLL s research team delivers intelligence, analysis and insight through market-leading reports and services that illuminate today s commercial real estate dynamics and identify tomorrow s challenges and opportunities. Our more than 400 global research professionals track and analyze economic and property trends and forecast future conditions in over 60 countries, producing unrivalled local and global perspectives. Our research and expertise, fueled by real-time information and innovative thinking around the world, creates a competitive advantage for our clients and drives successful strategies and optimal real estate decisions. This publication is the sole property of Jones Lang LaSalle IP, Inc. and must not be copied, reproduced or transmitted in any form or by any means, either in whole or in part, without prior written consent of Jones Lang LaSalle IP, Inc. COPYRIGHT JONES LANG LASALLE IP, INC. 2016

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