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1 Abstract sodales vulputate auctor. Nam lacus felis, fermentum sit amet nulla ac, tristique ultrices tellus. Integer rutrum aliquet sapien, eu fermentum magna pellentesque vitae. Integer semper viverra mauris vel pulvinar. Suspendisse sagittis malesuada urna. Praesent mauris diam, fringilla id fringilla ac, posuere non lorem. Vestibulum mauris ante, fringilla quis tortor sit amet, accumsan fermentum quam. Nulla dictum consectetur leo. Ut vulputate ipsum purus, a interdum nibh viverra et. Praesent aliquam sapien vel massa sodales bibendum. Nulla interdum accumsan lectus, sed auctor elit accumsan a. Suspendisse quis rhoncus nibh. In hac habitasse platea dictumst. Level 1 Heading for all major sections (Abstract, Introduction, Materials and Methods, Results, Discussion, etc.). Bold type, 0pt font. Only use italics and text formatting where needed (e.g. genus and species names, genes, etc.). NOTE: Do not cite figures, tables, supporting information, or references in the Abstract. Author Summary In in nunc aliquet eros imperdiet sodales. Ut non justo posuere, elementum erat nec, dictum leo. Aliquam semper consequat orci, sit amet tempor nisi pretium quis. Proin viverra hendrerit faucibus. Fusce lobortis nisi ut velit auctor sodales. Duis varius lacus elit, eu tristique tortor aliquam et. Vestibulum iaculis felis id ipsum adipiscing molestie. Cras consectetur sit amet sem id ultrices. Nullam gravida viverra neque, ut ultricies purus commodo id. Proin rhoncus quam ante, eu laoreet justo laoreet nec. Integer in est faucibus, lobortis quam sit amet, ultrices mi. Etiam augue risus, tincidunt eget dui vitae, feugiat malesuada sem. Introduction Author Summary Author Summary should directly follow Abstract Single paragraph in length. Do not include subsections. pharetra quam, vitae convallis nunc. Cras consectetur sit amet sem id ultrices. Nullam gravida viverra neque, ut ultricies purus commodo id. Proin rhoncus quam ante, eu laoreet justo laoreet nec.

2 Materials and Methods Vestibulum adipiscing urna ut lectus gravida, vitae (Figure 1) interdum. Donec tincidunt porta sem nec hendrerit. Vestibulum nec pharetra quam, vitae convallis nunc. Mauris in mattis sapien. Fusce sodales vulputate auctor. Nam lacus, fermentum sit Table 1, tristique ultrices tellus. Integer rutrum aliquet sapien, eu fermentum magna pellentesque vitae. Integer se viverra mauris vel pulvinar Table S1 aliquet sapien, Figure S1 in File S1. Figure/Table Citation Cite figures and tables in order. o Do not cite Figure before Figure 1. Figures and tables will be placed as close as possible to their respective citations. Supporting Information Citation Citations must include S before the number. If multiple pieces of Supporting Information are combined in a single file or appendix, please add in {File Name} to the citation. It is not required to cite each supporting information file. interdum. Donec p et q tincidunt porta sem nec hendrerit. p pq q 1 (1) Vestibulum nec pharetra quam, vitae convallis nunc. Mauris in mattis sapien. Fusce sodales vulputate auctor. Nam lacus felis, fermentum sit amet nulla ac, tristique ultrices tellus. Integer rutrum aliquet sapien, eu fermentum magna pellentesque vitae. Integer semper viverra mauris fermentum vel ( p q) 1. Display/Numbered Equation Format only in Mathtype as a Display Equation. Do not use Equation Tools or Symbol Font. Do not use Graphic Objects. Inline Equation Format in regular text or as an inline equation in Mathtype. Do not use Equation Tools or Symbol Font. Do not use Graphic Objects.

3 Genotyping sodales vulputate auctor. Nam lacus felis, fermentum sit amet nulla ac, tristique ultrices tellus. Integer rutrum aliquet sapien, eu fermentum magna pellentesque vitae. Integer semper viverra mauris vel pulvinar. Whole genome RFLP analysis sodales vulputate auctor. Level Heading Use Level headings for sub-sections of major sections. Bold type, 16pt font. Only use italics and text formatting where needed. Level 3 heading Use Level 3 headings for sub-sections within Level headings. Bold type, 1pt font. Only use italics and text formatting where needed. Results pharetra quam, vitae convalli. Discussion Suspendisse quis ultrices urna. Mauris eleifend consequat sem at semper. Fusce interdum ante metus, eu adipiscing tortor rhoncus et. Fusce eu erat ornare, posuere ligula quis, adipiscing augue. Mauris id velit eget libero ultricies iaculis. In faucibus purus elit, sit amet consectetur massa faucibus sit amet. Vivamus sed aliquam elit, ut pharetra tortor. Donec posuere sollicitudin egestas. Duis vitae malesuada dolor, vitae pulvinar mi. Maecenas non sem vitae risus rhoncus dapibus scelerisque vel quam.

4 Lorem ipsum dolor sit amet, consectetur adipiscing [1-5]. sodales vulputate auctor. Reference Citations Cite references in brackets (for example, [1] or [-5] or [3, 7, 9] ). References must be cited in order at first mention. Acknowledgments interdum. Acknowledgments Do not include funding or competing interests information in Acknowledgments. References References 1. Doe J, Data A, van Stats J, Testperson M, Ribosome D Jr, et al. (014) This is the article title. PLoS Genet 0(0): e0.. Doe J, Data A, van Stats J, Testperson M, Ribosome D Jr, et al. (In Press) Bunny dynamics in cartoon landscapes. PLoS Genet References should be listed after the main text, before the figure legends and supporting information. References with more than five authors should list the first five author names, followed by et al. Please see the PLOS Genetics guide for References here: g/static/guidelines#referen ces Figure Legends Figure 1. This is the Figure 1 Title. This is the Figure 1 legend. Figure. This is the Figure Title. This is the Figure legend. Figure Legends Include a separate section for figure legends after the References section. Use a Level 1 heading Do not include tables within legends. Use bold type for the figure titles.

5 Tables Table 1. This is the Table 1 Title. Chemical W Chemical X Chemical Y Chemical Z Chemical 1 Reaction 1W Reaction 1X Reaction 1Y Reaction 1Z Chemical Reaction W Reaction X Reaction Y Reaction Z Chemical 3 Reaction 3W a Reaction 3X Reaction 3Y b Reaction 3Z Chemical 4 Reaction 4W Reaction 4X Reaction 4Y Reaction 4Z Chemical 5 Reaction 5W Reaction 5X Reaction 5Y Reaction 5Z This is the Table 1 legend. a Table footnotes belong here. b Table footnotes belong here. Tables List tables after figure legends, in their own section. Tables must be cellbased in Microsoft Word. No vertically merged cells. No hard returns. Do not use empty rows to create spacing. Do not include graphic objects, images, or shading patterns. Typeset tables will be formatted to match PLOS Genetics style. See PLOS Genetics Table Guidelines for more complete instructions Supporting Information Legends Figure S1. This is the Figure S1 Title. This is the Figure S1 legend. Figure S. This is the Figure S Title. This is the Figure S legend. Table S1. This is the Table S1 Title. This is the Table S1 legend. Table S. This is the Table S Title. This is the Table S legend. File S1. This is the File S1 Title. This is the File S1 legend. Supporting Information Legends Include a separate section for Supporting Information legends at the end of the manuscript. Use a Level 1 heading. Use bold type for the titles. Supporting Information files do not require full legends, only titles are required. Please also see the PLOS Genetics Guidelines for Figures, Tables, and Supporting Information, which can be found here: For assistance preparing figures, please contact figures@plos.org For assistance with other formatting requirements, contact plosgenetics@plos.org

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