Medical Intelligence:

Transcription

1 Medical Intelligence: Big Data, Predictive Analytics, Machine Learning, and Artificial Intelligence Anthony C. Chang, MD, MBA, MPH Chief Intelligence and Innovation Officer Children s Hospital of Orange County Medical Director, Sharon Disney Lund Medical Intelligence and Innovation Institute Honors Cooperative Program in Biomedical Informatics/ Artificial Intelligence

2 Artificial Intelligence

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4 ANTHONY CHANG

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9 Artificial Intelligence Artificial Intelligence in Medicine ( Medical Intelligence )

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11 Missing Data

12 Unstructured Data

13 Excessive Data

14 Future Data

15 Genomic Medicine: Next Generation Sequencing

16 Precision Medicine: Continuous Data From Birth Nicholson J et al. Discovery Medicine, 7/2009.

17 PharmacoGenomic s: Personalized Medicine

18 Internet of EveryThing Patient Care Data Continuum

19 Little Information

20 Disparate Information Knowledge and Intelligence Network Disparate types of information are linked into multiscalar, multilateral, multidimensional relationships

21 The end of theory: The data deluge makes the scientific method (randomized controlled trials) obsolete. Chris Anderson, Wired

22 Algorithms

23 Big Data

24 Computational Power

25 Cloud Computing

26 Cognitive Computing: Natural Language Processing

27 Data Mining: New Knowledge from Big Data

28 Deep Learning: Machine Learning/ Neural Networks

29 Do We Humans REALLY Need AI?

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31 The Artificial Intelligence Brain

32 EME STREAMING ANALYTICS ARCHITECTURE Patient Bedside Monitoring Network Hospital Network ICU Monitors Med Surg Monitors Excel Medical BedMasterEx & BedComm IBM Infosphere Streams Various dashboards or notifications for clinicians & investigators OR Monitors ED Monitors Telemetry System Ancillary Monitoring Devices (vents, oximeters, video, etc) Hospital EMR and other data sources

33 The Artificial Intelligence Brain

34 The Artificial Intelligence Brain

35 Acquiring real-time / replay SQL/NoSQL/HTTP BMEX Runtime SQL Server Adaptation Layer Analytical Layer Delivery Layer InfoSphere Streams

36 The Artificial Intelligence Brain

37 The Artificial Intelligence Brain

38 The Artificial Intelligence Brain

39 function newimg = myconv2(img, kernel) newimg = zeros(size(img)); imgrow = size(img,1); imgcol = size(img,2); shift = (size(kernel,1)-1)/2; % maximum of how far we may go past border of img for row = 1:imgRow for col = 1:imgCol newimgval = 0; for x = -shift:shift for y = -shift:shift newrow = row - x; if (newrow < 1) continue; elseif (newrow > imgrow) continue; end newcol = col - y; if (newcol < 1) continue; elseif (newcol > imgcol) continue; end newimgval = newimgval + img(newrow, newcol)*kernel(x+shift+1,y+shift+1); end end newimg(row,col) = newimgval; end end

40 The Artificial Intelligence Brain

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43 The Artificial Intelligence Brain

44 Cortical Infrastructure

45 Cortical Infrastructure

46 BioIntelligence Framework

47 BioIntelligence Framework: A Living Expert Neural Network

48 Making the visible invisible

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51 Making the invisible visible

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54 HyperGraph Architecture

55 Intelligence-Based Medicine

56 Intelligence-Based Medicine

57 Intelligence-as-a- Service (IaaS)

58 Collective SuperIntelligence

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60 VERY SPECIAL THANKS TO: Sharon Disney Lund Medical Intelligence and Innovation Institute (MI3)

61 VERY SPECIAL THANKS TO: Sharon Disney Lund Medical Intelligence and Innovations Institute (MI3) Honors Cooperative Program in Biomedical Informatics/ Artificial Intelligence

62 VERY SPECIAL THANKS TO: Sharon Disney Lund Medical Intelligence and Innovations Institute (MI3) Honors Cooperative Program in Biomedical Informatics/ Artificial Intelligence and Scientist-in-Residence and Computer Science Department

63 VERY SPECIAL THANKS TO: Sharon Disney Lund Medical Intelligence and Innovations Institute (MI3) Honors Cooperative Program in Biomedical Informatics/ Artificial Intelligence and Scientist-in-Residence and Computer Science Department

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